業績

主要論文

Yoshioka D, Nakamura T, Kubota Y, and Takekawa M.
Formation of the NLRP3 inflammasome inhibits stress granule assembly by multiple mechanisms.
J. Biochem. mvae009, https://doi.org/10.1093/jb/mvae009 (2024)

Fujikawa D, Nakamura T, Yoshioka D, Li Z, Moriizumi H, Taguchi M, Tokai-Nishizumi N, Kozuka-Hata H, Oyama M, and Takekawa M. 論文解説
Stress granule formation inhibits stress-induced apoptosis by selectively sequestering executioner caspases.
Current Biology 33: 1967-1981.e8. doi: 10.1016/j.cub.2023.04.012 (2023)

Amada K, Hijiya N, Ikarimoto S, Yanagihara K, Hanada T, Hidano S, Kurogi S, Tsukamoto Y, Nakada C, Kinoshita K, Hirashita Y, Uchida T, Shin T, Yada K, Hirashita T, Kobayashi T, Murakami K, Inomata M, Shirao K, Aoki M, Takekawa M, Moriyama M.
Involvement of clusterin expression in the refractory response of pancreatic cancer cells to a MEK inhibitor.
Cancer Science
. doi.org/10.1111/cas.15735 (2023)

Moriizumi H, Kubota Y, Tsuchiya T, Naka R, and Takekawa M.
Caspase 3-specific cleavage of MEK1 suppresses ERK signaling and sensitizes cells to stress-induced apoptosis.
FEBS Open Bio. doi.org/10.1002/2211-5463.13574 (2023)

Ohe S, Kubota Y, Yamaguchi K, Takagi Y, Nashimoto J, Kozuka-Hata H, Oyama M, Furukawa Y, and Takekawa M. 論文解説
ERK-mediated NELF-A phosphorylation promotes transcription elongation of immediate-early genes by releasing promoter-proximal pausing of RNA polymerase II.
Nature Commun. 13:7476. doi: 10.1038/s41467-022-35230-4 (2022)

Kubota Y, Fujioka Y, Patil A, Takagi Y, Matsubara D, Iijima M, Momose I, Naka R, Nakai K, Noda N.N., and Takekawa M.論文解説
Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.
Nature Commun. 13: 4063 doi: 10.1038/s41467-022-31690-w (2022)

Tsukamoto Y, Kurogi S, Shibata T, Suzuki K, Hirashita Y, Fumoto S, Yano S, Yanagihara K, Nakada C, Mieno F, Kinoshita K, Fuchino T, Mizukami K, Ueda Y, Etoh T, Uchida T, Hanada T, Takekawa M, Daa T, Shirano K, Hironaka S, Murakami K, Inomata M, Hijiya N, and Moriyama M.
Enhanced phosphorylation of c-Jun by cisplatin treatment as a potential predictive biomarker for cisplatin response in combination with patient-derived tumor organoids.
Lab Invest. doi:10.1038/s41374-022-00827-2 (2022)

Watanabe M, Arii J, Takeshima K, Fukui A, Shimojima M, Kozuka-Hata H, Oyama M, Minamitani T, Yasui T, Kubota Y, Takekawa M, Kosugi I, Maruzuru Y, Koyanagi N, Kato A, Mori Y, and Kawaguchi Y.
Prohibitin-1 contributes to the cell-to-cell transmission of herpes simplex virus 1 via the MAPK/ERK signaling pathway.
Journal of Virology 95: e01413-20 doi: 10.1128/JVI.01413-20 (2021)

Matsushita M, Nakamura T, Moriizumi H, Miki H, and Takekawa M.論文解説
Stress-responsive MTK1 SAPKKK serves as a redox sensor that mediates delayed and sustained activation of SAPKs by oxidative stress.
Science Advances 6:eaay9778 doi:10.1126/sciadv.aay9778 (2020) *紹介記事 【 Link

Weng JS, Nakamura T, Moriizumi H, Takano H, Yao R, and Takekawa M.論文解説
MCRIP1 promotes the expression of lung-surfactant proteins in mice by disrupting CtBP-mediated epigenetic gene silencing.
Commun Biol. 2:227 doi:10.1038/s42003-019-0478-3 (2019)

Fujioka K, Kubota Y, and Takekawa M.
A novel method for the detection of O-GlcNAc-modified proteins by Lectin affinity gel electrophoresis.
Bio-protocol. 8: e3098, doi:10.21769/BioProtoc.3098 (2018)

Ichimanda M, Hijiya N, Tsukamoto Y, Uchida T, Nakada, C, Akagi T, Etoh T, Iha H, Inomata M, Takekawa M and Moriyama M.
Downregulation of DUSP4 enhances cell proliferation and invasiveness in colorectal carcinomas.
Cancer Sci. 109: 250-258 (2018)

Kubota Y, Fujioka K and Takekawa M.
WGA-based lectin affinity gel electrophoresis: a novel method for the detection of O-GlcNAc-modified proteins.
PLoS ONE 12: e0180714. doi:10.1371/journal.pone.0180714 (2017)

Iijima M, Kubota Y, Sawa R, Kubota Y, Hatano M, Igarashi M, Kawada M, Momose I, Takekawa M and Shibasaki M.
A guanine derivative as a new MEK inhibitor produced by Streptomuces sp. MK63-43F2.
J Antibiot. 71: 135-138 (2017)

Arimoto-Matsuzaki K, Saito H and Takekawa M.
TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis.
Nature Commun. 7: 10252 doi:10.1038/ncomms10252 (2016)

Hijiya N, Tsukamoto Y, Nakada C, Tung NL, Kai T, Matsuura K, Shibata K, Inomata M, Uchida T, Tokunaga A, Amada K, Shirao K, Yamada Y, Mori H, Takeuchi I, Seto M, Aoki M, Takekawa M, and Moriyama M.
Genomic loss of DUSP4 contributes to the progression of intraepitherial neoplasm of pancreas to invasive carcinoma.
Cancer Res. 76: 2612-2625 (2016)

Kinoshita E, Kinoshita-Kikuta E, Kubota Y, Takekawa M and Koike T.
A Phos-tag SDS-PAGE method that effectively uses phosphoproteomic data for profiling the phosphorylation dynamics of MEK1.
Proteomics 16: 1825-1836 (2016)

Kubota Y and Takekawa M.
Detection and functional analysis of SUMO-modified MEK.
Methods in Molecular Biology, Springer Press, in press (2016)

Ichikawa K, Kubota Y, Nakamura T, Weng JS, Tomida T, Saito H and Takekawa M.論文解説
MCRIP1, an ERK substrate, mediates ERK-induced gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP.
Molecular Cell 58: 35-46 (2015) [Abstract] [Faculty of 1000]

Tomida T, Takekawa M and Saito H.
Oscillation of p38 activity controls efficient pro-inflammatory gene expression.
Nature Commun. 6: 8350 doi:10.1038/ncomms9350 (2015)

Ohshima D, Arimoto-Matsuzaki K, Tomida T, Takekawa M and Ichikawa K.
Spatio-temporal dynamics and mechanisms of stress-granule assembly.
PLoS Comput. Biol. 11: e1004326 doi:10.1371/journal.pcbi.1004326 (2015)

Takekawa M and Kubota Y.
Mitogen-activated protein kinase signaling and cancer.
Protein Modifications in Pathogenic Dysregulation of Signaling, Springer Press, 211-231 (2015)

Ohshima D, Arimoto-Matsuzaki K, Tomida T, Takekawa M and Ichikawa K.
Stochastic Simulation of Stress Granules.
Protein Modifications in Pathogenic Dysregulation of Signaling, Springer Press, 77-93 (2015)

Sato Y, Goto E, Shibata Y, Kubota Y, Yamagata A, Goto-Ito S, Kubota K, Inoue J, Takekawa M, Tokunaga F,
Fukai S.
Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity.
Nature Struct. & Mol. Biol. 22: 222-229 (2014)

Nakamura T, Saito H and Takekawa M.論文解説
SAPK pathways and p53 cooperatively regulate PLK4 activity and centrosome integrity under stress.
Nature Commun. 4:1775 doi:10.1038/ncomms2752 (2013)

Tomida T, Osa S, Takekawa M, Iino Y and Saito H.
The temporal pattern of stimulation determines the extent and duration of MAPK activation in a caenorhabditis elegans sensory neuron.
Science Signaling 5, ra76 (2012)

Kubota Y, O’Grady P, Saito H and Takekawa M.論文解説
Oncogenic Ras abrogates MEK SUMOylation that suppresses the ERK pathway and cell transformation.
Nature Cell Biol. 13, 282-291 (2011) [Abstract] [Faculty of 1000]
*紹介記事【 Link 】: “ Editor’s Choice ” in Science Signaling / “ Highlights ” in A-IMBN Research 他

Otsuka M, Takata A, Yoshikawa T, Kojima K, Kishikawa T, Shibata C, Takekawa M, Yoshida H, Omata M, and Koike K.
Receptor for activated protein kinase C: Requirement for efficient microRNA function and reduced expression in hepatocellular carcinoma.
PLoS ONE 6, e24359 (2011)

Takekawa M, Kubota Y, Nakamura T and Ichikawa K.
Regulation of stress-activated MAP kinase pathways during cell fate decisions. (review)
Nagoya J. Med. Sci. 73, 1-14 (2010)

Tomida T, Takekawa M, O’Grady P and Saito H.
Stimulus-specific distinctions in spatial and temporal dynamics of stress-activated protein kinase kinase kinases revealed by FRET biosensor.
Mol. Cell. Biol. 29, 6117-6127 (2009)

Arimoto K, Fukuda H, Imajoh-Ohmi S, Saito H, and Takekawa M.
Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways.
Nature Cell Biol. 10, 1324-1332 (2008)
*紹介記事【 Link 】: “ Editor’s Choice ” in Science / Science Signaling / Nature Signaling Gateway

Miyake Z, Takekawa M, Ge Q and Saito H.
Activation of MTK1/MEKK4 by GADD45 through induced N-C dissociation and dimerization-mediated trans-autophosphorylation of the MTK1 kinase domain.
Mol. Cell. Biol. 27, 2765-2776 (2007)

Nakajima A, Komazawa-Sakon S, Takekawa M, Sasazuki T, Yeh W-C, Yagita H, Okumura K and Nakano H.
An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway.
EMBO J. 25, 5549–5559 (2006)

Fujimoto H, Onishi N, Kato N, Takekawa M, Xu X-Z, Kosugi A, Kondo T, Imamura M, Yoda A, Oishi I, and Minami Y.
Regulation of the anti-oncogenic Chk2 kinase by the oncogenic Wip1 phosphatase.
Cell Death Differ. 13, 1170-1180 (2006)

Takekawa, M., Tatebayashi, K., and Saito, H.
Conserved docking site is essential for activation of mammalian MAP kinase kinases by specific MAP kinase kinase kinases.
Molecular Cell 18, 295-306 (2005)

Chi H, Lu B, Takekawa M, Davis RJ, and Flavell RA.
GADD45β/GADD45γ and MEKK4 comprise a genetic pathway mediating STAT-independent IFNγ production in T cells.
EMBO J. 23, 1576–1586 (2004)

Takagaki K, Satoh T, Tanuma N, Masuda K, Takekawa M, Shima H and Kikuchi K.
Characterization of a novel low-molecular-mass dual-specificity phosphatase 3 (LDP-3) that enhances activation of JNK and p38.
Biochemical J. 383, 447-455 (2004)

Sakon S, Xue X, Takekawa M, Sasazuki T, Okazaki T, Kojima Y, Pia J-H, Yagita H, Okumura K, Doi T and Nakano H.
NF-κB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death.
EMBO J. 22, 3898-3909 (2003)

Tatebayashi K, Takekawa M and Saito H.
A docking site determining specificity of Pbs2 MAPKK to Ssk2/Ssk22 MAPKKKs in yeast HOG pathway.
EMBO J. 22, 3624-3634, (2003)

Mitsuhashi S, Shima H, Tanuma N, Matsuura N, Takekawa M, Urano T, Kataoka T, Ubukata M and Kikuchi K. Usage of tautomycetin, a novel inhibitor of protein phosphatase 1 (PP1) reveals that PP1 is a positive regulator of Raf-1 in COS-7 cells.
J. Biol. Chem. 278, 82-88, (2003)

Takekawa M, Tatebayashi K, Itoh F, Adachi M, Imai K and Saito H.
Smad-dependent GADD45β expression mediates delayed activation of p38 MAP kinase by TGF-β.
EMBO J. 21, 6473-6482 (2002) 【 Full-scan画像 】

Mita H, Tsutsui J, Takekawa M, Witten EA and Saito H.
Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding.
Mol. Cell. Biol. 22, 4544-4555, (2002)

Shonai T, Adachi M, Sakata K, Takekawa M, Endo T, Imai K and Hareyama M.
MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells.
Cell Death Differ. 9, 963-971, (2002)

Itoh M, Adachi M, Yasui H, Takekawa M, Tanaka H and Imai K.
Nuclear export of glucocorticoid receptor is enhanced by JNK-mediated phosphorylation.
Mol. Endocrinol. 16, 2382-2392, (2002)

Matsunaga T, Ishida T, Takekawa M, Nishimura S, Adachi M and Imai K.
Analysis of gene expression during maturation of immature dendritic cells derived from peripheral blood monocytes.
Scand. J. Immunol. 56, 593-601, (2002)

Nakamura K, Tanoue K, Satoh T, Takekawa M, Watanabe M, Shima H and Kikuchi K.
A novel low-molecular-mass dual-specificity phosphatase, LDP-2, with a naturally occurred substitution that affects substrate specificity.
J. Biochem. 132, 463-470 (2002)

Takekawa M, Adachi M, Nakahata A, Nakayama I, Itoh F, Tsukuda H, Taya Y and Imai K.
p53-inducible Wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation.
EMBO J., 19, 6517-6526, (2000)

Koyama Y, Adachi M, Sekiya M, Takekawa M and Imai K.
Histone deacetylase inhibitors suppress IL-2-mediated gene expression prior to induction of apoptosis.
Blood 96, 1490-1495, (2000)

Kaneki M, Kharbanda S, Pandey P, Yoshida K, Takekawa M, Liou J-R, Stone R and Kufe D.
Functional role for protein kinase Cβ as a regulator of stress-activated protein kinase activation and monocytic differentiation of myeloid leukemia cells.
Mol. Cell. Biol. 19, 461-470, (1999)

Takekawa M and Saito H.
A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK.
Cell 95, 521-530, (1998)

Takekawa M, Maeda T and Saito H.
Protein phosphatase 2Cα inhibits the human stress-responsive p38 and JNK MAPK pathways.
EMBO J. 17, 4744-4752, (1998)

Posas F, Takekawa M and Saito H.
Signal transduction by MAP kinase cascades in budding yeast.
Curr. Opin. Microbiol. 1, 175-182, (1998)

Takekawa M, Posas F and Saito H.
A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinase, MTK1, mediates stress-induced activation of the p38 and JNK pathways.
EMBO J. 16, 4973-4982, (1997)

Maeda T, Takekawa M and Saito H.
Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor.
Science 269, 554-558, (1995)

Takekawa M, Itoh F, Hinoda Y, Adachi M, Ariyama T, Inazawa J, Imai K and Yachi A.
Chromosomal localization of protein tyrosine phosphatase G1 gene and characterization of aberrant transcripts in human colon cancer cells.
FEBS Lett. 339, 222-228, (1994)

Adachi M, Maeda K, Takekawa M, Hinoda Y, Imai K, Sugiyama S and Yachi A.
High expression of CD56 (N-CAM) in a patient with cutaneous CD4-positive lymphoma.
Am. J. Hematol. 47, 278-282, (1994)

Adachi M, Sekiya M, Arimura Y, Takekawa M, Itoh F, Hinoda Y, Imai K and Yachi A.
Protein-tyrosine phosphatase expression in pre-B cell NALM-6.
Cancer Res. 52, 737-740, (1992)

Takekawa M, Itoh F, Hinoda Y, Arimura Y, Toyota M, Sekiya M, Adachi M, Imai K and Yachi A.
Cloning and characterization of a human cDNA encoding a novel putative cytoplasmic protein tyrosine phosphatase.
Biochem. Biophys. Res. Commun. 189, 1223-1230, (1992)

Arimura Y, Hinoda Y, Itoh F, Takekawa M, Tsujisaki M, Adachi M, Imai K and Yachi A.
cDNA cloning of new protein-tyrosine-phosphatases in human colon.
Tumor Biol. 13, 180-186, (1992)

Takekawa M, Imai K, Adachi M, Aoki S, Maeda K, Hinoda Y and Yachi A.
Hypereosinophilic syndrome accompanied with necrosis of finger tips.
Internal Med. 31, 1262-1266, (1992)

和文総説他

武川睦寛、久保田裕二
ERKシグナル伝達ネットワークと疾患
生化学 95巻5号 579-593 (2023)

吉岡大介、中村貴紀、武川睦寛 
ストレス顆粒によるストレス応答シグナルの制御と癌 
実験医学増刊「相分離 メカニズムと疾患」39巻10号 93-101 (2021)

武川睦寛
発癌シグナルによる癌抑制遺伝子のジーン・サイレンシング機構
文部科学省/日本学術振興会 科研費NEWS 2017年度 Vol.1 p18 (2017).

武川睦寛
未来をつなぐ風:数理科学を活用し、人体をシステムとして理解する
実験医学 34巻16号 2752 (2016).

武川睦寛
MAPキナーゼ情報伝達経路の活性制御機構と疾患発症機構の解明
生物物理化学 電気泳動 60巻 7-10 (2016).

武川睦寛
ストレス顆粒形成によるストレス誘導アポトーシスの制御と活性酸素によるその破綻
生物物理化学 電気泳動 60巻 s24 (2016).

久保田裕二, 松崎(有本)京子, 武川睦寛
ストレス顆粒の生理機能と疾患
医学のあゆみ 「特集:ストレスシグナルと疾患ー細胞恒常性維持機構の破綻と病態」
254巻5号 409-415 (2015).

武川睦寛
ストレス応答MAPK経路およびp53による中心体複製の制御
生化学 86巻 666-670 (2014).

松崎(有本)京子, 武川睦寛, 斎藤春雄
細胞質内ストレス顆粒の形成と細胞生存への寄与
放射線生物学 49巻3号 248-262 (2014).

久保田祐二, 武川睦寛
Ras/MAPK症候群および孤発性癌で認められるMEK遺伝子変異体の異常活性化機構と疾患発症メカニズムの解明
生物物理化学 57巻 s21(2013).

久保田祐二, 武川睦寛
p38とそのカスケード
Clinical Neuroscience 特集「神経系のMAPキナーゼ」31巻 657-660 (2013).

中村貴紀, 武川睦寛
JNK/p38-AP1経路とストレス反応系
日本臨床増刊号「分子標的薬:がんから他疾患までの治癒をめざして」 70巻 218-224 (2012).

中村貴紀, 武川睦寛
細胞内シグナル伝達と分子標的薬剤の作用機構
Medical Science Digest「特集:分子標的薬」 38巻 14-17 (2012).

久保田祐二, 中亮介, 武川睦寛
ユビキチンおよびユビキチン様タンパク質によるMAPキナーゼ経路の制御
実験医学増刊「シグナル伝達研究最前線2012ー翻訳後修飾,解析技術,疾患との連関から創薬応用までー」30巻 72-79 (2012).

武川睦寛
MAPキナーゼ・シグナル伝達システムの活性制御機構と癌におけるその破綻
生物物理化学 56巻 s85 (2012)

武川睦寛, 久保田裕二
がん遺伝子産物RasはMEKのSUMO化によるERK経路の不活性化を阻止し発がんを導く
ライフサイエンス 新着論文レビュー(オンラインジャーナル)(2011)

武川睦寛
ストレス顆粒によるストレス応答シグナルの制御と癌
実験医学増刊「秒進分歩する癌研究と分子標的治療」29巻2号 125-131 (2011)

武川睦寛
宇宙環境ストレスに応答するp38/JNKシグナル伝達経路の活性制御機構の解明
ー 細胞はどの様にして環境ストレス刺激を細胞内シグナルへと変換するか ー
宇宙環境利用に関する公募地上研究ニュース Vol. 8 (2007)

武川睦寛
ドッキング・サイトを介したMAPキナーゼ情報伝達経路のシグナル特異性決定機構
日本アルコール・薬物医学会雑誌 40巻4号  (2005)

武川睦寛, 舘林和夫, 斎藤春雄
ストレス応答MAPキナーゼ
蛋白質・核酸・酵素「MAPキナーゼ研究 現状と展望」47巻11号 1379-1389 (2002)

中山一郎, 武川睦寛, 小関至, 築田浩幸, 佐々木茂, 今井浩三
マウス・ヒトキメラ抗erbB-2抗体を用いたアポトーシス誘導機序の検討
日本分子腫瘍マーカー研究会誌 Vol. 18: 41-42 (2002)

武川睦寛, 斎藤春雄
プロテインホスファターゼによるp53の生理機能の制御
実験医学増刊「p53研究の新たな挑戦」19巻9号 1074-1079 (2001)

佐々木茂, 小関至, 中山一郎, 武川睦寛, 石田禎夫, 辻崎正幸, 今井浩三
癌遺伝子産物に対する抗体を用いた悪性腫瘍の治療
臨床免疫 35巻3号 371-376 (2001)

小畑俊郎, 佐藤亜由美, 南貴恵, 水越常徳, 村上里絵子, 山本博幸, 武川睦寛, 菅谷壽晃, 高橋裕樹, 今井浩三
大動脈炎症候群を合併した若年性関節リウマチの一例
日本内科学会雑誌90巻12号 2475-2476 (2001)

小関至, 佐々木茂, 武川睦寛, 中山一郎, 三原真美, 安達靖代, 岩田徳和, 金戸宏行, 石田禎夫, 伊東文生, 辻崎正幸, 今井浩三
erbB-2陽性胃癌細胞株JRSTに対する抗erbB-2マウス・ヒトキメラモノクローナル抗体によるアポトーシスの誘導
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中心性漿液性網脈絡膜症を呈した強皮症合併蛋白漏出性胃腸症の1例
日本臨床免疫学会会誌 24巻3号 125-132 (2001)

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中枢神経症状を伴い急性発症を呈したベーチェット病の1例
リウマチ科 25巻5号 457-462 (2001)

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関節症状を主徴としたACTH単独欠損症の1症例
リウマチ 40巻6号 904-909 (2001)

武川睦寛, 今井浩三
MAPキナーゼスーパーファミリーのシグナル伝達における役割
イラスト医学&サイエンスシリーズ「細胞内シグナル伝達がわかる」(羊土社)20-27 (2000)

佐々木茂, 武川睦寛, 小関至, 金戸宏行, 岩田徳和, 石田禎夫, 辻崎正幸, 今井浩三
抗ErbB-2マウス・ヒトキメラモノクローナル抗体のアポトーシス誘導による腫瘍増殖抑制
Biotherapy 14巻5号 490-492 (2000)

佐々木茂, 小関至, 武川睦寛, 辻崎正幸, 今井浩三
新しい免疫の啓蟄 外科学とのかかわり 癌の抗体治療
日本外科学会雑誌 101巻9号 607-611 (2000)

斎藤春雄, 武川睦寛
ヒトストレス応答MAPキナーゼ情報伝達系の制御機構
生物物理化学 43巻2号 49-55 (1999)

高岡朝子, 伊東文生, 垣内英樹, 武川睦寛, 有村佳昭, 生田茂夫, 日野田裕治, 今井浩三
大腸癌におけるprotein tyrosine phosphatasesの発現検討
腫瘍マーカー研究会誌 12巻, 73-75 (1998)

高岡晃教, 垣内英樹, 伊東文生, 有村佳昭, 武川睦寛, 日野田裕治, 今井浩三.
大腸癌におけるprotein tyrosine phosphatasesの発現検討.
消化器癌 6, 123-129 (1996)

中村英明, 淡川照仁, 山本博幸, 武川睦寛, 今井浩三, 笠井美智子, 川原田信, 佐藤保則.
高齢者における経口腸管洗浄剤ニフレックによる大腸内視鏡検査前処置の検討.
薬理と臨床 23, 265-273 (1995)

武川睦寛, 今井浩三
接着分子異常
血液・腫瘍科 29巻1号 35-44 (1994)

武川睦寛, 今井浩三, 谷内昭
Immunotoxinの現況
病態生理 11巻6号 432-438 (1992)

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