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Fitness flux in SARS-CoV-2 and seasonal influenza H3N2

学友会セミナー

開催情報

開催日時 2025 年 9 月 19日(金)16:00 ~ 17:00
開催場所 1号館講堂
講師 Trevor Bedford, Ph.D.
所属・職名 Fred Hutchinson Cancer Center and Howard Hughes Medical Institute・ Professor
演題 Fitness flux in SARS-CoV-2 and seasonal influenza H3N2
世話人 〇主たる世話人:佐藤佳(システムウイルス学分野)
世話人:石井健(ワクチン科学分野)
 

概要

SARS-CoV-2 and seasonal influenza rapidly evolve to escape from human immunity. This manifests as the emergence and spread of variant viruses. Here I characterize this process of viral population turnover, quantify the rate of fitness change in the viral population and relate this to the influx of new fitness altering mutations. I also characterize genomic changes that predict changes in viral fitness.