Unveiling the protective role of ribosomal RNA against auto-immunity
学友会セミナー
開催情報
| 開催日時 | 2024年7月4日（木）16：00 ～ 17：30 |
|---|---|
| 開催場所 | 4号館 3階 会議室 |
| 講師 | Michael P. Gantier |
| 所属・職名 | Research Group Leader, Nucleic Acids and Innate Immunity Laboratory, Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research |
| 演題 | Unveiling the protective role of ribosomal RNA against auto-immunity |
| 世話人 | 主たる世話人：
三宅 健介（感染遺伝学分野）
川口 寧（ウイルス病態制御分野）
|
概要
A/Prof Gantier's team has pioneered discoveries of the immunosuppressive effects of synthetic oligonucleotides. In ground-breaking studies which he will present today, they recently discovered that cleavage products of these oligonucleotides into very short fragments could block TLR7/8 sensing, a finding which has widespread implications for RNA therapeutics such as mRNA vaccines, and our broad understanding of inflammation in autoimmunity.