About usOverview
Our laboratory explores two major themes at the heart of life science.
1. We seek to understand development and reproduction, fundamental biological processes, by connecting perspectives across molecules, cells, tissues, and organisms. We investigate germ cell formation, the tissue environment that supports spermatogenesis, and the regulatory mechanisms of early development to uncover how life is passed on to the next generation.
2. By combining genome editing, genetically engineered mouse and rat models, pluripotent stem cells, and single-cell analysis, we develop new animal experimental systems for testing biological mechanisms at the organismal level. In particular, through next-generation model animal technologies that reproduce human gene structures and regulatory mechanisms in mice, we aim to understand human diseases and reproductive and developmental abnormalities that have been difficult to analyze using conventional models.
NewsLatest
View all- 2026/6/24
- An article explaining full-length gene-humanization technology was published in the Close-up Experimental Methods section of Yodosha's Jikken Igaku (Experimental Medicine), July 2026 issue.
- 2026/6/17
- A collaborative study with the Kawaoka Laboratory at the University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA) was published in Cell.
- 2026/5/10
- Associate Professor Ozawa's paper on the role of Sertoli cell PTBP1 in controlling spermatogenesis was featured on Nature Japan's X account.
- 2026/5/1
- Dr. Aya Kitabayashi joined the laboratory as a project researcher on May 1, 2026.
- 2026/4/24
- Associate Professor Ozawa gave a presentation and joined a discussion on full-length gene-humanization technology, the TECHNO method, on Channel JBA: Japan Bioindustry Association. Please take a look.
- 2026/4/1
- Dr. Shino Nagata received her Ph.D. and continues her research as a project researcher.
- 2026/4/1
- Project Assistant Professor Junpei Taguchi moved to the Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University, as a lecturer on April 1, 2026. We wish him continued success in his new position.
- 2026/2/20
- Associate Professor Ozawa gave a luncheon seminar at the FY2025 AdAMS Research Achievement Meeting, held at the Biwako Hotel on February 19 and 20, 2026.
- 2026/2/4
- Associate Professor Ozawa's paper on the role of Sertoli cell PTBP1 in controlling spermatogenesis was published in Communications Biology.
- 2026/1/15
- Project Assistant Professor Taguchi's paper on the development of full-length gene-humanized mouse technology was published in Nature Communications. The work was also featured in an IMSUT press release.
See collaborative publications here