We performed brain imaging of mouse cerebral malaria after CUBIC clearance and found that P. bergheiANKA parasites accumulate in olfactory bulb of mouse.

What would happen if olfactory bulb is removed?
Answer can be found at:
Matsuo-Dapaah J, Lee MSJ, Ishii KJ, Tainaka K, Coban C. Using a new three-dimensional CUBIC tissue-clearing method to examine the brain during experimental cerebral malaria. International Immunology, 2021, dxab060
Link:https://doi.org/10.1093/intimm/dxab060

https://immunology.sciencemag.org/content/2/12/eaam8093.long

Zhao H, Aoshi T, Kawai S, Mori Y, Konishi A, Ozkan M, Fujita Y, Haseda Y, Shimizu M, Kohyama M, Kobiyama K, Eto K, Nabekura J, Horii T, Ishino T, Yuda M, Hemmi H, Kaisho T, Akira S, Kinoshita M, Tohyama K, Yoshioka Y, Ishii KJ, Coban C. Olfactory Plays a Key Role in Spatiotemporal Pathogenesis of Cerebral Malaria. Cell Host Microbe, 2014, 15(5): 551-63. DOI:10.1016/j.chom.2014.04.008