"Combined landscape of single-nucleotide variants and copy-number alterations in clonal hematopoiesis"
Nature Medicine オンライン版 2021年7月8日 doi:10.1038/s41591-021-01411-9
クローン性造血の臨床予後への影響を解明 ―遺伝子変異とコピー数異常の統合的な知見―
解説
論文情報
Ryunosuke Saiki1, Yukihide Momozawa2, Yasuhito Nannya1, Masahiro M Nakagawa1,3, Yotaro Ochi1,Tetsuichi Yoshizato1, Chikashi Terao4, Yutaka Kuroda 5, Yuichi Shiraishi6, Kenichi Chiba6, Hiroko Tanaka7, Atsushi Niida8, Seiya Imoto9, Koichi Matsuda10, Takayuki Morisaki11, Yoshinori Murakami11, Yoichiro Kamatani4,10, Shuichi Matsuda5, Michiaki Kubo12, Satoru Miyano7, Hideki Makishima1, Seishi Ogawa1,3,13
所属機関：1Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, 3Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan, 4Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, 5Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan, 7Department of Integrated Data Science, M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan, 8Laboratory of Molecular Medicine, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan, 9Division of Health Medical Intelligence, Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan, 10Department of Computational Biology and Medical Sciences, Graduate school of Frontier Sciences, The University of Tokyo, Tokyo, Japan, 11Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan, 12RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, 13Department of Medicine, Centre for Haematology and Regenerative Medicine, Karolinska Institute, Stockholm, Sweden
所属機関：1Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, 3Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan, 4Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, 5Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan, 7Department of Integrated Data Science, M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan, 8Laboratory of Molecular Medicine, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan, 9Division of Health Medical Intelligence, Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan, 10Department of Computational Biology and Medical Sciences, Graduate school of Frontier Sciences, The University of Tokyo, Tokyo, Japan, 11Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan, 12RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, 13Department of Medicine, Centre for Haematology and Regenerative Medicine, Karolinska Institute, Stockholm, Sweden
