FY2022 Research Reports (International Joint Research Projects)

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Completed Project
Project No.	PI	Project Title
K1001	John F. Tisdale	Development of a small-size b-globin vector for efficient vector production and gene marking
K1002	Masato Yamamoto	Development of a CD133-targeted adenoviral vector system
K1007	Jianda HU	Development of novel investigational HLA-A24 restrictive cancer vaccine for multiple myeloma
K2001	Jacob Corn	Development of a novel off-target detection tool for CRISPR-Cas3
K2002	Konrad Hochedlinger	Modulating epigenetic regulation to promote muscle regeneration and rejuvenation
K2003	Hyeseong Cho	Elucidation of mechanisms underlying eukaryotic DNA repair and transcription
K2006	Watcharin Loilome	Multi-omic analysis toward an understanding of therapeutic response for a precision medicine in cholangiocarcinoma
K2007	Miguel Esteban	Dissecting the molecular roadmap of in vivo reprogramming
K2009	Jiangning Song	Artificial intelligence-enabled cancer diagnosis, type classification and mutation prediction by leveraging deep learning and histopathology image analysis
K2102	Leyi Wei	Dual learning based generative adversarial networks for imputation of single-cell RNA-seq data
K3002	Daniel SAUTER	Regulation of cellular gene expression by endogenous retroviruses in infectious and non-infectious diseases
K3004	Eicke Latz	The impact of DNases on alveolar hemorrhage
K3005	Omar Abdel-Wahab	Clonal hematopoiesis and a variety of related disorders in the aged population


Continuing Project
Project No.	PI	Project Title
K22-1039	Yan Xiyun	Ferritin nanocaged doxorubicin for targeted hepatocellular carcinoma therapy
K22-1040	鄭允文	Reconstruction of human liver in Fah–/–Rag2–/–IL2rg–/– rats with hiPSC derived liver organoids
K22-1041	DUPREZ Estelle	Inflammation, hematopoietic aging, and clonal drift: deciphering the role of the transcription factor PLZF
K22-1059	COQ Jacques-Olivier	Mesenchymal Stromal Cell Therapy to Prevent Neurodevelopmental Disorders related to Low-Birth-Weight
K22-1072	Passegue Emmanuelle	Development of novel therapeutics targeting hematopoietic stem cell (HSC) aging
K22-1073	Wilkinson Adam	Hematopoietic stem cell rejuvenation therapies
K22-2043	Patrick Tan	Understanding of epigenetic heterogeneity in intractable cancers
K22-2056	何暁東	Functional polarization of tumour-associated macrophages by tumor microenvironment
K22-2057	Leonhardt Heinrich	Regulation and Function of DNA methylation
K22-2103	Yeh Iwei	The development of acral melanoma model and a novel early diagnostic method based on stem cell dynamics
K22-3045	Ernst Peter	Development of mucosal vaccines designed for infant based on the understanding of the infantile nasopharyngeal and gut mucosal immune system
K22-3046	Leonard Warren	Control of T cell and NK cell exhaustion to overcome viral infection and cancer development
K22-3058	Ginhoux Florent	Investigating Putative Dendritic Cell Precursors (pre-DC) with Neutrophil Progenitor Properties
K22-3062	Tsai Catherine	Harnessing the group A streptococcus pilus to develop novel universal influenza vaccines
K22-3063	Katsikis Peter	Human Systems Immunology of vaccine and immunotherapy
K22-3068	Hirasawa Kensuke	Programmed cell death induced by human coronavirus infection
K22-3069	Qin Zhihai	To study the molecular mechanism of COVID-19 protein ORF3a to stimulate the production of cytokine in macrophages
K22-3076	Simon Anna	Elucidation of mechanisms involved in tissue specific immunity during infection and vaccination
K22-3082	Mi Kaixia	Analysis of the mechanisms of co-infection with Mycobacterium and HIV in human macrophage linage cells

FY2022 Research Reports (International Joint Research Projects)

Completed Project

Continuing Project