Scientific Papers

Transmissibility, infectivity, and immune resistance of the SARS-CoV-2 BA.2.86 variant
The Lancet Infectious Diseases (online) September 18,2023
doi:10.1016/S1473-3099(23)00575-3
Keiya Uriu#, Jumpei Ito#, Yusuke Kosugi, Yuri L Tanaka, Yuka Mugita, Ziyi Guo, Alfredo HINAY, Jr, Olivia Putri, Yoonjin Kim, Ryo Shimizu, MST Monira Begum, Michael Jonathan, The Genotype to Phenotype Japan (G2P-Japan) Consortium, Akatsuki Saito, Terumasa Ikeda, Kei Sato*.
（#Equal contribution; *Corresponding author）

Antiviral efficacy of the SARS-CoV-2 XBB breakthrough infection sera against Omicron subvariants including EG.5 
The Lancet Infectious Diseases (online) September 11,2023
doi:10.1016/S1473-3099(23)00553-4
Yu Kaku#, Yusuke Kosugi#, Keiya Uriu#, Jumpei Ito#, Alfredo A Hinay Jr., Jin Kuramochi, Kenji Sadamasu, Kazuhisa Yoshimura, Hiroyuki Asakura, Mami Nagashima, The Genotype to Phenotype Japan (G2P-Japan) Consortium, Kei Sato*.
（#Equal contribution; *Corresponding author）

In vitro and in vivo characterization of SARS-CoV-2 resistant to ensitrelvir
Nature Communications (online) July 15,2023
doi:10.1038/s41467-023-40018-1
Maki Kiso*, Seiya Yamayoshi¶, Shun Iida, Yuri Furusawa, Yuichiro Hirata, 
Ryuta Uraki, Masaki Imai, Tadaki Suzuki, Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

In vitro and in vivo characterization of SARS-CoV-2 strains resistant to nirmatrelvir
Nature Communications (online) July 4,2023
doi:10.1038/s41467-023-39704-x
Maki Kiso*, Yuri Furusawa, Ryuta Uraki, Masaki Imai, Seiya Yamayoshi¶, and Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

High body temperature increases gut microbiota-dependent host resistance to influenza A virus and SARS-CoV-2 infection
Nature Communications (online) June 30, 2023
doi:10.1038/s41467-023-39569-0 
Minami Nagai#, Miyu Moriyama#, Chiharu Ishii#, Hirotake Mori, Hikaru Watanabe, Taku Nakahara, Takuji Yamada, Dai Ishikawa, Takamasa Ishikawa, Akiyoshi Hirayama, Ikuo Kimura, Akihito Nagahara, Toshio Naito*, Shinji Fukuda*, Takeshi Ichinohe*
#Equal contribution; *Corresponding author

Transmission and re-infection of Omicron variant XBB.1.5 in hamsters
eBioMedicine (online) June 21, 2023
doi:10.1016/j.ebiom.2023.104677
Peter J. Halfmann*, Ryuta Uraki*, Makoto Kuroda, Kiyoko Iwatsuki-Horimoto, Seiya Yamayoshi, Mutsumi Ito, Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

Efficacy of antivirals and mRNA vaccination against an XBF clinical isolate
The Lancet Regional Health - Western Pacific (online) May 11, 2023
doi:10.1016/j.lanwpc.2023.100777
Ryuta Uraki*, Mutsumi Ito*, Maki Kiso*, Seiya Yamayoshi, Kiyoko Iwatsuki-Horimoto, Yuko Sakai-Tagawa, Masaki Imai, Michiko Koga, Shinya Yamamoto, Eisuke Adachi, Makoto Saito, Takeya Tsutsumi, Amato Otani, Yukie Kashima, Tetsuhiro Kikuchi, James Theiler, Hiroshi Yotsuyanagi, Yutaka Suzuki, Bette Korber, and Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants
Nature Communications (online) May 16, 2023
doi:10.1038/s41467-023-38435-3
Tomokazu Tamura#, Jumpei Ito#, Keiya Uriu#, Jiri Zahradnik#, Izumi Kida#, Yuki Anraku#, Hesham Nasser#, Maya Shofa#, Yoshitaka Oda#, Spyros Lytras#, Naganori Nao, Yukari Itakura, Sayaka Deguchi, Rigel Suzuki, Lei Wang, MST Monira Begum, Shunsuke Kita, Hisano Yajima, Jiei Sasaki, Kaori Sasaki-Tabata, Ryo Shimizu, Masumi Tsuda, Yusuke Kosugi, Shigeru Fujita, Lin Pan, Daniel Sauter, Kumiko Yoshimatsu, Saori Suzuki, Hiroyuki Asakura, Mami Nagashima, Kenji Sadamasu, Kazuhisa Yoshimura, Yuki Yamamoto, Tetsuharu Nagamoto, Gideon Schreiber, Katsumi Maenaka, The Genotype to Phenotype Japan (G2P-Japan) Consortium, Takao Hashiguchi, Terumasa Ikeda, Takasuke Fukuhara, Akatsuki Saito, Shinya Tanaka*, Keita Matsuno*, Kazuo Takayama* & Kei Sato*
（#Equal contribution; *Corresponding author）

Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ.1.1 variant
Nature Communications (online) May 11, 2023
doi:10.1038/s41467-023-38188-z
Jumpei Ito#, Rigel Suzuki#, Keiya Uriu#, Yukari Itakura#, Jiri Zahradnik#, Kanako Terakado Kimura#, Sayaka Deguchi#, Lei Wang#, Spyros Lytras#, Tomokazu Tamura, Izumi Kida, Hesham Nasser, Maya Shofa, Mst Monira Begum, Masumi Tsuda, Yoshitaka Oda, Tateki Suzuki, Jiei Sasaki, Kaori Sasaki-Tabata, Shigeru Fujita, Kumiko Yoshimatsu, Hayato Ito, Naganori Nao, Hiroyuki Asakura, Mami Nagashima, Kenji Sadamasu, Kazuhisa Yoshimura, Yuki Yamamoto, Tetsuharu Nagamoto, Jin Kuramochi, Gideon Schreiber, The Genotype to Phenotype Japan (G2P-Japan) Consortium, Akatsuki Saito, Keita Matsuno, Kazuo Takayama, Takao Hashiguchi*, Shinya Tanaka*, Takasuke Fukuhara*, Terumasa Ikeda* & Kei Sato*
（#Equal contribution; *Corresponding author）

Virological characteristics of the SARS-CoV-2 Omicron XBB.1.16 variant
 The Lancet Infectious Diseases (online) May 3, 2023
doi:10.1016/S1473-3099(23)00278-5
Daichi Yamasoba#,Keiya Uriu#,Arnon Plianchaisuk#,Yusuke Kosugi#,Lin Pan#,Jiri Zahradnik,The Genotype to Phenotype Japan (G2P-Japan) Consortium,Jumpei Ito,Kei Sato*
（#Equal contribution; *Corresponding author）

Replicative capacity of SARS-CoV-2 omicron variants BA.5 and BQ.1.1 at elevated temperatures
The Lancet Microbe (online) April 24, 2023
doi:10.1016/S2666-5247(23)00100-3
Yukiko Muramoto*, Senye Takahashi, Peter J. Halfmann, Shimpei Gotoh, Takeshi Noda¶, Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

In SARS-CoV-2 delta variants, Spike-P681R and D950N promote membrane fusion, Spike-P681R enhances spike cleavage, but neither substitution affects pathogenicity in hamsters
eBioMedicine (online) April 10, 2023
doi:10.1016/j.ebiom.2023.104561
Yuri Furusawa*, Maki Kiso, Shun Iida, Ryuta Uraki, Yuichiro Hirata, Masaki Imai, Tadaki Suzuki, Seiya Yamayoshi, and Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

Characterization of SARS-CoV-2 Omicron BA.2.75 clinical isolates
Nature Communications (online) March 23, 2023
doi:10.1038/s41467-023-37059-x
Ryuta Uraki*, Shun Iida*, Peter J. Halfmann*, Seiya Yamayoshi*, Yuichiro Hirata, Kiyoko Iwatsuki-Horimoto, Maki Kiso, Mutsumi Ito, Yuri Furusawa, Hiroshi Ueki, Yuko Sakai-Tagawa, Makoto Kuroda, Tadashi Maemura, Taksoo Kim, Sohtaro Mine, Noriko Iwamoto, Rong Li, Yanan Liu, Deanna Larson, Shuetsu Fukushi, Shinji Watanabe, Ken Maeda, Zhongde Wang, Norio Ohmagari, James Theiler, Will Fischer, Bette Korber¶, Masaki Imai¶, Tadaki Suzuki¶, and Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

Efficacy of Antiviral Agents and Bivalent mRNA Vaccines against a CH.1.1 isolate
Lancet Infectious Diseases (online) March 7, 2023
doi:10.1016/S1473-3099(23)00132-9
Ryuta Uraki*, Mutsumi Ito*, Maki Kiso*, Seiya Yamayoshi, Kiyoko Iwatsuki-Horimoto, Yuko Sakai-Tagawa, Yuri Furusawa, Masaki Imai, Michiko Koga, Shinya Yamamoto, Eisuke Adachi3, Makoto Saito, Takeya Tsutsumi, Amato Otani, Yukie Kashima, Tetsuhiro Kikuchi, Hiroshi Yotsuyanagi, Yutaka Suzuki, and Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

Antiviral and bivalent vaccine efficacy against an omicron XBB.1.5 isolate
Lancet Infectious Diseases (online) February 8, 2023
doi:10.1016/S1473-3099(23)00070-1
Ryuta Uraki*, Mutsumi Ito*, Maki Kiso*, Seiya Yamayoshi, Kiyoko Iwatsuki-Horimoto, Yuri Furusawa, Yuko Sakai-Tagawa, Masaki Imai, Michiko Koga, Shinya Yamamoto, Eisuke Adachi, Makoto Saito, Takeya Tsutsumi, Amato Otani, Tetsuhiro Kikuchi, Hiroshi Yotsuyanagi, Peter J. Halfmann, Andrew Pekosz, Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

Enhanced transmissibility, infectivity and immune resistance of the SARS-CoV-2 Omicron XBB.1.5 variant
The Lancet Infectious Diseases (online) January 31, 2023
doi:10.1016/S1473-3099(23)00051-8
Keiya Uriu#,Jumpei Ito#,Jiri Zahradnik#,Shigeru Fujita,Yusuke Kosugi,Gideon Schreiber,The Genotype to Phenotype Japan (G2P-Japan) Consortium,Kei Sato*
（#Equal contribution; *Corresponding author）

Sensitivity of rapid antigen tests for COVID-19 during the Omicron variant outbreak among players and staff members of the Japan Professional Football League and clubs: A retrospective observational study
BMJ Open  (online) January 30, 2023
doi:10.1136/bmjopen-2022-067591
Michio Murakami, Hitoshi Sato, Tomoko Irie, Masashi Kamo, Wataru Naito, Tetsuo Yasutaka, Seiya Imoto

SARS-CoV-2 transmission from virus-infected dead hamsters
mSphere  (online) January 10, 2023
doi:10.1128/msphere.00411-22
Kiyoko Iwatsuki-Horimoto*, Hiroshi Ueki, Mutsumi Ito, Sayaka Nagasawa, Yuichiro Hirata, Kenichiro Hashizume, Kazuho Ushiwata, Hirotaro Iwase, Yohsuke Makino, Tetsuo Ushiku, Shinji Akitomi, Masaki Imai, Hisako Saitoh, Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

Are twindemics occurring?
「Influenza and Other Respiratory Viruses」  (online) December 25, 2022
doi:10.1111/irv.13090
Emi Takashita*¶, Shinji Watanabe, Hideki Hasegawa, Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

Humoral immune evasion of the omicron subvariants BQ.1.1 and XBB
Lancet Infectious Diseases  (online) December 7, 2022
doi:10.1016/S1473-3099(22)00816-7
Ryuta Uraki*, Mutsumi Ito*, Yuri Furusawa*, Seiya Yamayoshi, Kiyoko Iwatsuki-Horimoto, Eisuke Adachi, Makoto Saito, Michiko Koga, Takeya Tsutsumi, Shinya Yamamoto, Amato Otani, Maki Kiso, Yuko Sakai-Tagawa, Hiroshi Ueki, Hiroshi Yotsuyanagi, Masaki Imai, and Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

Efficacy of Antiviral Agents against Omicron BQ.1.1 and XBB Subvarians 
New England Journal of Medicine (NEJM)  (online) December 7, 2022
doi:10.1056/NEJMc2214302
Masaki Imai*, Mutsumi Ito*, Maki Kiso*, Seiya Yamayoshi*, Ryuta Uraki, Shuetsu Fukushi, Shinji Watanabe, Tadaki Suzuki, Ken Maeda, Yuko Sakai-Tagawa, Kiyoko Iwatsuki-Horimoto, Peter Halfmann, Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

In Vitro Efficacy of Antiviral Agents against the Omicron Subvariant BA.4.6
New England Journal of Medicine (NEJM)   (online) November 16, 2022
doi:10.1056/NEJMc2211845
Emi Takashita*, Seiya Yamayoshi*, Peter Halfmann, Nancy Wilson, Hunter Ries, Alex Richardson, Max Bobholz, William Vuyk, Robert Maddox, David A. Baker, Thomas C. Friedrich, David H. O’Connor, Ryuta Uraki, Mutsumi Ito, Yuko Sakai-Tagawa, Eisuke Adachi, Makoto Saito, Michiko Koga, Takeya Tsutsumi, Kiyoko Iwatsuki-Horimoto, Maki Kiso, Hiroshi Yotsuyanagi, Shinji Watanabe, Hideki Hasegawa, Masaki Imai, Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

Characterization of SARS-CoV-2 Omicron BA.4 and BA.5 isolates in rodents
Nature  (online) November 2, 2022
doi:10.1038/s41586-022-05482-7
Ryuta Uraki*, Peter J. Halfmann*, Shun Iida*, Seiya Yamayoshi*, Yuri Furusawa, Maki Kiso, Mutsumi Ito, Kiyoko Iwatsuki-Horimoto, Sohtaro Mine, Makoto Kuroda, Tadashi Maemura, Yuko Sakai-Tagawa, Hiroshi Ueki, Rong Li, Yanan Liu, Deanna Larson, Shuetsu Fukushi, Shinji Watanabe, Ken Maeda, Andrew Pekosz, Ahmed Kandeil, Richard J Webby, Zhongde Wang, Masaki Imai¶, Tadaki Suzuki¶, Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant
Cell Host & Microbe  (online) October 9, 2022
doi:10.1016/j.chom.2022.10.003
Akatsuki Saito#,Tomokazu Tamura#,Jiri Zahradnik#,Sayaka Deguchi#,Koshiro Tabata#,Yuki Anraku#,Izumi Kimura#,Jumpei Ito#,Daichi Yamasoba#,Hesham Nasser,Mako Toyoda,Kayoko Nagata,Keiya Uriu,Yusuke Kosugi,Shigeru Fujita,Maya Shofa,MST Monira Begum,Ryo Shimizu,Yoshitaka Oda,Rigel Suzuki,Hayato Ito,Naganori Nao,Lei Wang,Masumi Tsuda,Kumiko Yoshimatsu,Jin Kuramochi,Shunsuke Kita,Kaori Sasaki-Tabata,Hideo Fukuhara,Katsumi Maenaka,Yuki Yamamoto,Tetsuharu Nagamoto,Hiroyuki Asakura,Mami Nagashima,Kenji Sadamasu,Kazuhisa Yoshimura,Takamasa Ueno,Gideon Schreiber,Akifumi Takaori-Kondo,The Genotype to Phenotype Japan (G2P-Japan) Consortium,Kotaro Shirakawa,Hirofumi Sawa,Takashi Irie,Takao Hashiguchi,Kazuo Takayama,Keita Matsuno,Shinya Tanaka*,Terumasa Ikeda*,Takasuke Fukuhara*,Kei Sato*
（#Equal contribution; *Corresponding author）

Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants including BA.4 and BA.5
Cell (online) September 13, 2022
doi:10.1016/j.cell.2022.09.018
Izumi Kimura#,Daichi Yamasoba#,Tomokazu Tamura#,Naganori Nao#,Tateki Suzuki#,Yoshitaka Oda#,Shuya Mitoma#,Jumpei Ito#,Hesham Nasser#,Jiri Zahradnik#,Keiya Uriu,Shigeru Fujita,Yusuke,Kosugi,Lei Wang,Masumi Tsuda,Mai Kishimoto,Hayato Ito,Rigel Suzuki,Ryo Shimizu,MST Monira Begum,Kumiko Yoshimatsu,Kanako Terakado Kimura,Jiei Sasaki,Kaori Sasaki-Tabata,Yuki Yamamoto,Tetsuharu Nagamoto,Jun Kanamune,Kouji Kobiyama,Hiroyuki Asakura,Mami Nagashima,Kenji Sadamasu,Kazuhisa Yoshimura,Kotaro Shirakawa,Akifumi Takaori-Kondo,Jin Kuramochi,Gideon Schreiber,Ken J. Ishii,The Genotype to Phenotype Japan (G2P-Japan) Consortium,Takao Hashiguchi*,Terumasa Ikeda*,Akatsuki Saito*,Takasuke Fukuhara*,Shinya Tanaka*,Keita Matsuno*,Kei Sato*
（#Equal contribution; *Corresponding author）

Efficacy of Antiviral Agents against the Omicron Subvariant BA.2.75
New England Journal of Medicine (NEJM) (online) September 7, 2022
doi: 10.1056/NEJMc2209952
Emi Takashita*, Seiya Yamayoshi*, Shuetsu Fukushi, Tadaki Suzuki, Ken Maeda, Yuko Sakai-Tagawa, Mutsumi Ito, Ryuta Uraki, Peter Halfmann, Shinji Watanabe, Makoto Takeda, Hideki Hasegawa, Masaki Imai, Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author


Effectiveness of HEPA filters at removing infectious SARS-CoV-2 from the air
mSphere (online) August 10, 2022
doi:10.1128/msphere.00086-22
Hiroshi Ueki*, Michiko Ujie*, Yosuke Komori, Tatsuo Kato, Masaki Imai, and Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force
Nature Communications (online) August 22, 2022
doi:10.1038/s41467-022-32276-2
Wang, Q.S. et al. 

Association of SARS-CoV-2 load in wastewater with reported COVID-19 cases in the Tokyo 2020 Olympic and Paralympic Village from July to September 2021
JAMA Network Open (online) August 22, 2022
doi:10.1001/jamanetworkopen.2022.26822
 Masaaki Kitajima，Michio Murakami，Syun-suke Kadoya，Hiroki Ando，Tomohiro Kuroita，Hiroyuki Katayama，Seiya Imoto

DOCK2 is involved in the host genetics and biology of severe COVID-19
Nature (online) August 8, 2022
doi:10.1038/s41586-022-05163-5
Namkoong H and Edahiro R et al.

Cross-border transmissions of the Delta substrain AY.29 during Tokyo Olympic and Paralympic Games
Frontiers in Microbiology (online) August 3, 2022
doi:10.3389/fmicb.2022.883849
Takahiko Koyama*,  Reitaro Tokumasu, Kotoe Katayama, Ayumu Saito, Michiharu Kudo and Seiya Imoto
*Corresponding author Efficacy of Antibodies and Antiviral Drugs against Omicron BA.2.12.1, BA.4, and BA.5 Subvariants
New England Journal of Medicine (NEJM) (online) July 20, 2022
doi:10.1056/NEJMc2207519
Emi Takashita*, Seiya Yamayoshi*, Viviana Simon, Harm van Bakel, Emilia Mia Sordillo, Andrew Pekosz, Shuetsu Fukushi, Tadaki Suzuki, Ken Maeda, Peter Halfmann, Yuko Sakai-Tagawa, Mutsumi Ito, Shinji Watanabe, Masaki Imai, Hideki Hasegawa, Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

Metalloproteinase-dependent and TMPRSS2-independent cell surface entry pathway of SARS-CoV-2 requires the furin-cleavage site and the S2 domain of spike protein
mBio (online) June 16, 2022
doi:10.1128/mbio.00519-22
Mizuki Yamamoto, Jin Gohda, Ayako Kobayashi, Keiko Tomita, Youko Hirayama, Naohiko Koshikawa, Motoharu Seiki, Kentaro Semba, Tetsu Akiyama, Yasushi Kawaguchi and Jun-ichiro Inoue*
(*Corresponding author)

Therapeutic efficacy of monoclonal antibodies and antivirals against SARS-CoV-2 Omicron BA.1 in Syrian hamsters
Nature Microbiology (online) June 15, 2022
doi:10.1038/s41564-022-01170-4
Ryuta Uraki*, Maki Kiso*, Masaki Imai*, Seiya Yamayoshi, Mutsumi Ito, Seiichiro Fujisaki, Emi Takashita, Michiko Ujie, Yuri Furusawa, Atsuhiro Yasuhara, Kiyoko Iwatsuki-Horimoto, Yuko Sakai-Tagawa, Shinji Watanabe, Hideki Hasegawa, and Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

Neutralisation sensitivity of SARS-CoV-2 omicron subvariants to therapeutic monoclonal antibodies
The Lancet Infectious Diseases (online) June 8, 2022
doi:10.1016/S1473-3099(22)00365-6
Daichi Yamasoba#,Yusuke Kosugi#,Izumi Kimura#,Shigeru Fujita,Keiya Uriu,Jumpei Ito,Kei Sato*
（#Equal contribution; *Corresponding author）

Characterization of the emerging SARS-CoV-2 B.1.621 (Mu) variant
Science Translational Medicine(online) May 17, 2022
doi:10.1126/scitranslmed.abm4908
Peter J. Halfmann*, Makoto Kuroda, Tammy Armbrust, James Theiler, Ariane Balaram, Gage K. Moreno, Molly A. Accola, Kiyoko Iwatsuki-Horimoto, Riccardo Valdez, Emily Stoneman, Katrina Braun, Seiya Yamayoshi, Elizabeth Somsen, John J. Baczenas, Keiko Mitamura, Masao Hagihara, Eisuke Adachi, Michiko Koga, Matthew McLaughlin, William Rehrauer, Masaki Imai, Shinya Yamamoto, Takeya Tsutsumi, Makoto Saito, Thomas C. Friedrich, Shelby L. O’Connor, David H. O’Conner, Aubree Gordon, Bette Korber, and Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

Characterization and antiviral susceptibility of SARS-CoV-2 Omicron/BA.2
Nature (online) May 16, 2022
doi:10.1038/s41586-022-04856-1
Ryuta Uraki*, Maki Kiso*, Shun Iida*, Masaki Imai*, Emi Takashita*, Makoto Kuroda*, Peter J. Halfmann, Samantha Loeber, Tadashi Maemura, Seiya Yamayoshi, Seiichiro Fujisaki, Zhongde Wang, Mutsumi Ito, Michiko Ujie, Kiyoko Iwatsuki-Horimoto, Yuri Furusawa, Ryan Wright, Zhenlu Chong, Seiya Ozono, Atsuhiro Yasuhara, Hiroshi Ueki, Yuko Sakai-Tagawa, Rong Li, Yanan Liu, Deanna Larson, Michiko Koga, Takeya Tsutsumi, Eisuke Adachi, Makoto Saito, Shinya Yamamoto, Masao Hagihara, Keiko Mitamura, Tetsuro Sato, Masayuki Hojo, Shin-ichiro Hattori, Kenji Maeda, Riccardo Valdez, IASO study team, Moe Okuda, Jurika Murakami, Calvin Duong, Sucheta Godbole, Daniel C. Douek, Ken Maeda, Shinji Watanabe, Aubree Gordon, Norio Ohmagari, Hiroshi Yotsuyanagi, Michael S. Diamond, Hideki Hasegawa, Hiroaki Mitsuya, Tadaki Suzuki, and Yoshihiro Kawaoka¶
*:First author
¶:Corresponding author

Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike
Cell (online) May1, 2022
doi:10.1016/j.cell.2022.04.035
Daichi Yamasoba#,Izumi Kimura#,Hesham Nasser#,Yuhei Morioka#,Naganori Nao#,Jumpei Ito#,Keiya Uriu#,Masumi Tsuda#,Jiri Zahradnik#,Kotaro Shirakawa,Rigel Suzuki,Mai Kishimoto,Yusuke Kosugi,Kouji Kobiyama,Teppei Hara,Mako Toyoda,Yuri L. Tanaka,Erika P. Butlertanaka,Ryo Shimizu,Hayato Ito,Lei Wang,Yoshitaka Oda,Yasuko Orba,Michihito Sasaki,Kayoko Nagata,Kumiko Yoshimatsu,Hiroyuki Asakura,Mami Nagashima,Kenji Sadamasu,Kazuhisa Yoshimura,Jin Kuramochi,Motoaki Seki,Ryoji Fujiki,Atsushi Kaneda,Tadanaga Shimada,Taka-aki Nakada,Seiichiro Sakao,Takuji Suzuki,Takamasa Ueno,Akifumi Takaori-Kondo,Ken J. Ishii,Gideon Schreiber,The Genotype to Phenotype Japan (G2P-Japan) Consortium,Hirofumi Sawa,Akatsuki Saito*,Takashi Irie*,Shinya Tanaka*,Keita Matsuno*,Takasuke Fukuhara*,Terumasa Ikeda*,Kei Sato*
（#Equal contribution; *Corresponding author）
  
Efficacy of vaccination and previous infection against the Omicron BA.1 variant in Syrian hamsters
Cell Reports  (online) March 27, 2022
doi:10.1016/j.celrep.2022.110688
Peter J. Halfmann*¶, Makoto Kuroda, Tadashi Maemura, Shiho Chiba, Tammy Armbrust,
Ryan Wright, Ariane Balaram, Kelsey R. Florek, Allen C. Bateman, and Yoshihiro
Kawaoka¶
*:First author
¶:Corresponding author

A 265-Nanometer High-Power Deep-UV Light-Emitting Diode Rapidly Inactivates SARS-CoV-2 Aerosols
mSphere  (online) March 17, 2022
doi:10.1128/msphere.00941-21
Hiroshi Ueki, Mutsumi Ito, Yuri Furusawa, Seiya Yamayoshi, Shin-ichiro Inoue*, and Yoshihiro Kawaoka*

Correlation Analysis between Gut Microbiota Alterations and the Cytokine Response in Patients with Coronavirus Disease during Hospitalization
Microbiology Spectrum  (online) March 7, 2022
doi:10.1128/spectrum.01689-21
Taketoshi Mizutani, Aya Ishizaka, Michiko Koga, Kazuhiko Ikeuchi, Makoto Saito, Eisuke Adachi, Seiya Yamayoshi, Kiyoko Iwatsuki-Horimoto, Atsuhiro Yasuhara, Hiroshi Kiyono, Tetsuro Matano, Yutaka Suzuki, Takeya Tsutsumi, Yoshihiro Kawaoka, Hiroshi Yotsuyanagi

Efficacy of Antiviral Agents against the SARS-CoV-2 Omicron Subvariant BA.2
New England Journal of Medicine (NEJM)  (online) March 9, 2022
doi:10.1056/NEJMc2201933
Emi Takashita*, Noriko Kinoshita, Seiya Yamayoshi, Yuko Sakai-Tagawa, Seiichiro Fujisaki, Mutsumi Ito, Kiyoko Iwatsuki-Horimoto, Peter Halfmann, Shinji Watanabe, Kenji Maeda, Masaki Imai, Hiroaki Mitsuya, Norio Ohmagari, Makoto Takeda, Hideki Hasegawa, Yoshihiro Kawaoka*

Long-term, infection-acquired immunity against the SARS-CoV-2 Delta variant in a hamster model
Cell repots  (online) February 15, 2022
doi: 10.1016/j.celrep.2022.110394
 Peter J. Halfmann*, Makoto Kuroda, Tammy Armbrust, Molly Accola, Riccardo Valdez, Theresa Kowalski-Dobson, William Rehrauer, Aubree Gordon, and Yoshihiro Kawaoka*
*Corresponding author

COVID-19 wastewater surveillance implemented in the Tokyo 2020 Olympic and Paralympic Village
Journal of Travel Medicine (online) February 3, 2022
doi:10.1093/jtm/taac004
Masaaki Kitajima，Michio Murakami，Ryo Iwamoto，Hiroyuki Katayama，Seiya Imoto

Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity
Nature (online) February 1, 2022
doi:10.1038/s41586-022-04474-x
Bo Meng#, Isabella A.T.M Ferreira#, Adam Abdullahi#, Niluka Goonawardane#, Akatsuki Saito#, Izumi Kimura#, Daichi Yamasoba#, Pehuén Perera Gerba, Saman Fatihi, Surabhi Rathore, Samantha K Zepeda, Guido Papa, Steven A. Kemp,  Terumasa Ikeda, Mako Toyoda,  Toong Seng Tan, Jin Kuramochi, Shigeki Mitsunaga, Takamasa Ueno, Kotaro Shirakawa, Akifumi Takaori-Kondo, Teresa Brevini, Donna L. Mallery, Oscar J. Charles, CITIID-NIHR BioResource COVID-19 Collaboration, The Genotype to Phenotype Japan (G2P-Japan) Consortium, Ecuador-COVID19 Consortium, John E Bowen, Anshu Joshi, Alexandra C. Walls, Laurelle Jackson, Sandile Cele, Darren Martin, Kenneth G.C. Smith, John Bradley, John A. G. Briggs, Jinwook Choi, Elo Madissoon, Kerstin Meyer, Petra Mlcochova, Lourdes Ceron-Gutierrez, Rainer Doffinger, Sarah Teichmann, Matteo Pizzuto, Anna de Marco, Davide Corti, Alex Sigal, Leo James, David Veesler, Myra Hosmillo, Joo Hyeon Lee, Fotios Sampaziotis, Ian G Goodfellow, Nicholas J. Matheson, Lipi Thukral, Kei Sato*, Ravindra K. Gupta*
（#Equal contribution; *Corresponding author） 

Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant
Nature (online) Febuary 1, 2022
doi:10.1038/s41586-022-04462-1
Rigel Suzuki#, Daichi Yamasoba#, Izumi Kimura#, Lei Wang#, Mai Kishimoto#, Jumpei Ito#, Yuhei Morioka, Naganori Nao, Hesham Nasser, Keiya Uriu, Yusuke Kosugi, Masumi Tsuda, Yasuko Orba, Michihito Sasaki, Ryo Shimizu, Ryoko Kawabata, Kumiko Yoshimatsu, Hiroyuki Asakura, Mami Nagashima, Kenji Sadamasu, Kazuhisa Yoshimura, The Genotype to Phenotype Japan (G2P-Japan) Consortium, Hirofumi Sawa, Terumasa Ikeda, Takashi Irie, Keita Matsuno*, Shinya Tanaka*, Takasuke Fukuhara* & Kei Sato*
（#Equal contribution; *Corresponding author）

CRISPR-Cas3-based diagnostics for SARS-CoV-2 and influenza virus
iScience (online) January 30, 2022
doi:10.1016/j.isci.2022.103830
Kazuto Yoshimi, Kohei Takeshita, Seiya Yamayoshi, Satomi Shibumura, Yuko Yamauchi, Masaki Yamamoto, Hiroshi Yotsuyanagi, Yoshihiro Kawaoka, Tomoji Mashimo

Efficacy of antibodies and antivirals against a SARS-CoV-2 Omicron variant
New England Journal of Medicine (NEJM) (online) January 26, 2022 doi:10.1056/NEJMc2119407
Emi Takashita, Noriko Kinoshita, Seiya Yamayoshi, Yuko Sakai-Tagawa, Seiichiro Fujisaki, Mutsumi Ito, Kiyoko Iwatsuki-Horimoto, Shiho Chiba, Peter Halfmann, Hiroyuki Nagai, Makoto Saito, Eisuke Adachi, David Sullivan, Andrew Pekosz, Shinji Watanabe, Kenji Maeda, Masaki Imai, Hiroshi Yotsuyanagi, Hiroaki Mitsuya, Norio Ohmagari, Makoto Takeda, Hideki Hasegawa, Yoshihiro Kawaoka 

SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters
Nature (online) January 21, 2022
ⅾoi:10.1038/s41586-022-04441-6
Peter J. Halfmann*, Shun Iida*, Kiyoko Iwatsuki-Horimoto*, Tadashi Maemura*, Maki Kiso*, Suzanne M. Scheaffer, Tamarand L. Darling, Astha Joshi, Samantha Loeber, Gagandeep Singh, Stephanie L. Foster, Baoling Ying, James Brett Case, Zhenlu Chong, Bradley Whitener, Juan Moliva, Katharine Floyd, Michiko Ujie, Noriko Nakajima, Mutsumi Ito, Ryan Wright, Ryuta Uraki, Prajakta Warang, Matt Gagne, Rong Li, Yuko Sakai-Tagawa, Yanan Liu, Deanna Larson, Jorge E. Osorio, Juan P. Hernandez-Ortiz, Amy R. Henry, Karl Ciouderis, Kelsey Florek, Mit Patel, Abby Odle, Lok-Yin Roy Wong, Allen C. Bateman, Zhongde Wang, Venkata-Viswanadh Edara, Zhenlu Chong, John Franks, Trushar Jeevan, Thomas Fabrizio, Jennifer DeBeauchamp, Lisa Kercher, Patrick Seiler, Ana Silvia Gonzalez-Reiche, Emilia Mia Sordillo, Lauren A Chang, Harm van Bakel, Viviana Simon, PSP study group, Daniel C. Douek, Nancy J. Sullivan, Larissa B. Thackray, Hiroshi Ueki, Seiya Yamayoshi, Masaki Imai, Stanley Perlman, Richard J. Webby, Robert A. Seder, Mehul S. Suthar, Adolfo Garcia-Sastre, Michael Schotsaert, Tadaki Suzuki, Adrianus C.M. Boon¶, Michael S. Diamond¶, and Yoshihiro Kawaoka¶
*: First author
¶:Corresponding author

The SARS-CoV-2 Lambda variant exhibits enhanced infectivity and immune resistance
Cell Reports (online) December 18, 2021
doi:10.1016/j.celrep.2021.110218
Izumi Kimura#, Yusuke Kosugi#, Jiaqi Wu#, Jiri Zahradnik, Daichi Yamasoba, Erika P. Butlertanaka, Yuri L. Tanaka, Keiya Uriu, Yafei Liu, Nanami Morizako, Kotaro Shirakawa, Yasuhiro Kazuma, Ryosuke Nomura, Yoshihito Horisawa, Kenzo Tokunaga, Takamasa Ueno, Akifumi Takaori-Kondo, Gideon Schreiber, Hisashi Arase, The Genotype to Phenotype Japan (G2P-Japan) Consortium, Chihiro Motozono, Akatsuki Saito, So Nakagawa*, Kei Sato*
（#Equal contribution; *Corresponding authors；＄Lead contact） 

Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation
Nature (online) November 25, 2021
doi:10.1038/s41586-021-04266-9
Akatsuki Saito#, Takashi Irie#, Rigel Suzuki#, Tadashi Maemura#, Hesham Nasser#, Keiya Uriu#, Yusuke Kosugi#, Kotaro Shirakawa, Kenji Sadamasu, Izumi Kimura, Jumpei Ito, Jiaqi Wu, Kiyoko Iwatsuki-Horimoto, Mutsumi Ito, Seiya Yamayoshi, Samantha Loeber, Masumi Tsuda, Lei Wang, Seiya Ozono, Erika P. Butlertanaka, Yuri L. Tanaka, Ryo Shimizu, Kenta Shimizu, Kumiko Yoshimatsu, Ryoko Kawabata, Takemasa Sakaguchi, Kenzo Tokunaga, Isao Yoshida, Hiroyuki Asakura, Mami Nagashima, Yasuhiro Kazuma, Ryosuke Nomura, Yoshihito Horisawa, Kazuhisa Yoshimura, Akifumi Takaori-Kondo, Masaki Imai, The Genotype to Phenotype Japan (G2P-Japan) Consortium, Shinya Tanaka*, So Nakagawa*, Terumasa Ikeda*, Takasuke Fukuhara*, Yoshihiro Kawaoka* & Kei Sato*
（#Equal contribution; *Corresponding author） 
 
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion
Nature (online) september 6, 2021
doi:10.1038/s41586-021-03944-y
Petra Mlcochova*, Steven Kemp*, Mahesh Shanker Dhar*, Guido Papa, Bo Meng, Isabella A.T.M Ferreira, Rawlings Datir, Dami A. Collier, Anna Albecka, Sujeet Singh, Rajesh Pandey, Jonathan Brown, Jie Zhou, Niluka Goonawardane, Swapnil Mishra, Charles Whittaker, Thomas Mellan , Robin Marwal, Meena Datta, Shantanu Sengupta, Kalaiarasan Ponnusamy, Venkatraman Srinivasan Radhakrishnan, Adam Abdullahi, Oscar Charles, Partha Chattopadhyay, Priti Devi, Daniela Caputo, Tom Peacock, Dr Chand Wattal, Neeraj Goel, Ambrish Satwik, Raju Vaishya, Meenakshi Agarwal, The Indian SARS-CoV-2 Genomics Consortium (INSACOG), The CITIID-NIHR BioResource COVID-19 Collaboration, 
The Genotype to Phenotype Japan (G2P-Japan) Consortium, Antranik Mavousian, Joo Hyeon Lee, Jessica Bassi , Chiara Silacci-Fegni, Christian Saliba, Dora Pinto,Takashi Irie, Isao Yoshida, William L. Hamilton, Kei Sato, Samir Bhatt, Seth Flaxman, Leo C. James, Davide Corti, Luca Piccoli, Wendy S. Barclay, Partha Rakshit*, Anurag Agrawal*, Ravindra K. Gupta*

Inactivation of Novel Coronavirus and Alpha Variant by Photo-renewable CuxO/TiO2 Nanocomposites
ChemRxiv (online) July 16, 2021
doi:10.33774/chemrxiv-2021-tnrs7 
Tetsu Tatsuma, Makoto Nakakido, Takeshi Ichinohe, Yoshinori Kuroiwa, Kengo Tomioka, Chang Liu, Nobuhiro Miyamae, Tatsuya Onuki, Kouhei Tsumoto, Kazuhito Hashimoto, Toru Wakihara

SARS-CoV-2 B.1.617 mutations L452R and E484Q are not synergistic for antibody evasion
Journal of Infectious Diseases (online) July 14, 2021
doi:10.1093/infdis/jiab368 
Isabella Ferreira#, Steven Kemp#, Rawlings Datir#,  Akatsuki Saito, Bo Meng, Partha Rakshit,  Akifumi Takaori-Kondo, Yusuke Kosugi, Keiya Uriu, Izumi Kimura, Kotaro Shirakawa, Adam Abdullahi, The CITIID-NIHR BioResource COVID-19 Collaboration, The Indian SARS-CoV-2 Genomics Consortium (INSACOG), Anurag Agarwal,  Seiya Ozono, Kenzo Tokunaga, The Genotype to Phenotype Japan (G2P-Japan) Consortium, Kei Sato*, Ravindra K. Gupta*（#Equal contribution; *Corresponding authors） 

Mapping the human genetic architecture of COVID-19
Nature (online) July 8, 2021
doi:10.1038/s41586-021-03767-x
The COVID-19 Host Genetics Initiative

The human microbiome and COVID-19: A systematic review
PLoS One 2021 Jun 23;16(6):e0253293
doi:10.1371/journal.pone.0253293
Yamamoto S, Saito M, Tamura A, Prawisuda D, Mizutani T, Yotsuyanagi H 

Characterization of a new SARS-CoV-2 variant that emerged in Brazil
Proceedings of the National Academy of Sciences of the United States of America (online)
June 17, 2021
doi:10.1073/pnas.2106535118
Masaki Imai*, Peter J. Halfmann, Seiya Yamayoshi, Kiyoko Iwatsuki-Horimoto, Shiho Chiba, Tokiko Watanabe, Noriko Nakajima, Mutsumi Ito, Makoto Kuroda, Maki Kiso, Tadashi Maemura, Kenta Takahashi, Samantha Loeber, Masato Hatta, Michiko Koga, Hiroyuki Nagai, Shinya Yamamoto, Makoto Saito, Eisuke Adachi, Osamu Akasaka, Morio Nakamura, Ichiro Nakachi, Takayuki Ogura, Rie Baba, Kensuke Fujita, Junichi Ochi, Keiko Mitamura, Hideaki Kato, Hideaki Nakajima, Kazuma Yagi, Shinichiro Hattori, Kenji Maeda, Tetsuya Suzuki, Yusuke Miyazato, Riccardo Valdez, Carmen Gherasim, Yuri Furusawa, Moe Okuda, Michiko Ujie, Tiago J. S. Lopes, Atsuhiro Yasuhara, Hiroshi Ueki, Yuko SakaiTagawa, Amie J. Eisfeld, John J. Baczenas, David A. Baker, Shelby L. O’Connor, David H. O’Connor, Shuetsu Fukushi, Tsuguto Fujimoto, Yudai Kuroda, Aubree Gordon, Ken Maeda, Norio Ohmagari, Norio Sugaya, Hiroshi Yotsuyanagi, Hiroaki Mitsuya, Tadaki Suzuki, Yoshihiro Kawaoka*

SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity
Cell Host & Microbe (online) June 14, 2021
doi:10.1016/j.chom.2021.06.006 
Chihiro Motozono,Mako Toyoda#,Jiri Zahradnik#,Akatsuki Saito#,Hesham Nasser#,Toong Seng Tan,Isaac Ngare,Izumi Kimura,Keiya Uriu,Yusuke Kosugi,Yuan Yue,Ryo Shimizu,Jumpei Ito,Shiho Torii,Akiko Yonekawa,Nobuyuki Shimono,Yoji Nagasaki,Rumi Minami,Takashi Toya,Noritaka Sekiya,Takasuke Fukuhara,Yoshiharu Matsuura,Gideon Schreiber,The Genotype to Phenotype Japan (G2P-Japan) Consortium,Terumasa Ikeda*,So Nakagawa*,Takamasa Ueno*,Kei Sato*
（#Equal contribution; *Corresponding authors）

N-(4-Hydroxyphenyl) retinamide suppresses SARS-CoV-2 spike protein-mediated cell-cell fusion by a dihydroceramide Δ4-desaturase 1-independent mechanism
Journal of Virology （online）June 9, 2021
doi:10.1128/JVI.00807-21
Hayashi Y, Tsuchiya K, Yamamoto M, Nemoto-Sasaki Y, Tanigawa K, Hama K, Ueda Y, Tanikawa T, Gohda J, Maeda K, Inoue J, Yamashita A

COVID-19 risk assessment at the opening ceremony of the Tokyo 2020 Olympic Games
Microbial Risk Analysis（online）March 21, 2021
doi:10.1016/j.mran.2021.100162
Michio Murakami*, Fuminari Miura, Masaaki Kitajima, Kenkichi Fujii, Tetsuo Yasutaka, Yuichi Iwasaki, Kyoko Ono, Yuzo Shimazu, Sumire Sorano, Tomoaki Okuda, Akihiko Ozaki, Kotoe Katayama, Yoshitaka Nishikawa, Yurie Kobashi, Toyoaki Sawano, Toshiki Abe, Masaya M.Saito, Masaharu Tsubokura, Wataru Naito, Seiya Imoto (*corresponding author)

Sarbecovirus ORF6 proteins hamper the induction of interferon signaling
Cell Reports（online） March 12, 2021
doi:10.1016/j.celrep.2021.108916
Izumi Kimura, Yoriyuki Konno, Keiya Uriu, Kristina Hopfensperger, Daniel Sauter, So Nakagawa, Kei Sato* (*corresponding author)

Increased risk of rhinovirus infection in children during the coronavirus disease-19 pandemic
Influenza and Other Respiratory Viruses（online）2021;00:1–7.
doi:10.1111/irv.12854
Emi Takashita, Chiharu Kawakami, Tomoko Momoki, Miwako Saikusa, Kouhei Shimizu, Hiroki Ozawa, Makoto Kumazaki, Shuzo Usuku, Nobuko Tanaka, Ichiro Okubo, Hiroko Morita, Shiho Nagata, Shinji Watanabe, Hideki Hasegawa, Yoshihiro Kawaoka 
  Protective Immunity and Persistent Lung Sequelae in Domestic Cats after SARS-CoV-2 Infection
Emerging Infectious Diseases (online)  January 7, 2021 doi:10.3201/eid2702.203884
Shiho Chiba, Peter J. Halfmann, Masato Hatta, Tadashi Maemura, Shufang Fan, Tammy Armbrust, Olivia M. Swartley, LaTasha K. Crawford, Yoshihiro Kawaoka
Description

SARS-CoV-2 D614G Variant Exhibits Efficient Replication ex vivo and Transmission in vivo
Science (online)  November 12, 2020 doi:10.1126/science.abe8499
Yixuan J. Hou, Shiho Chiba, Peter Halfmann, Camille Ehre, Makoto Kuroda, Kenneth H Dinnon III, Sarah R. Leist, Alexandra Schäfer, Noriko Nakajima, Kenta Takahashi, Rhianna E. Lee, Teresa M. Mascenik, Rachel Graham, Caitlin E. Edwards, Longping V. Tse, Kenichi Okuda, Alena J. Markmann, Luther Bartelt, Aravinda de Silva, David M. Margolis, Richard C. Boucher, Scott H. Randell, Tadaki Suzuki, Lisa E. Gralinski, Yoshihiro Kawaoka* and Ralph S. Baric* 
Description 

コロナ禍におけるリスクコミュニケーションと偏見・差別  *only in Japanese
月刊福祉, 103(10):15-18, 全国社会福祉協議会, 2020/11 
MUTO Kaori (武藤香織)

Effectiveness of face masks in preventing airborne transmission of SARS-CoV-2
mSphere (online) October 21, 2020 doi:10.1128/mSphere.00637-20
Hiroshi Ueki, Yuri Furusawa, Kiyoko Iwatsuki-Horimoto, Masaki Imai, Hiroki Kabata, Hidekazu Nishimura, and Yoshihiro Kawaoka* (*corresponding author) 

The association of coagulopathy with liver dysfunction in patients with COVID-19  
Hepatol Res. doi:10.1111/hepr.13577
Tsutsumi T, Saito M, Nagai H, Yamamoto S, Ikeuchi K, Lim LA, Adachi E, Koga M, Okushin K, Akai H, Kunimatsu A, Yotsuyanagi H. (Division of Infectious Diseases, Advanced Clinical Research Center)

「新型コロナ専門家有志の会」の全世代に向けた情報発信の活動より  *only in Japanese
保健の科学, 62(10); 652-657, 2020/10.
MUTO Kaori (武藤 香織), 仁木 崇嗣, 田中 幹人

Antibody Response to SARS-CoV-2 in people living with HIV  
Journal of Microbiology, Immunology and Infection  doi:10.1016/j.jmii.2020.09.005
Yamamoto S, Saito M, Nagai E, Toriuchi K, Nagai H, Yotsuyanagi H, Nakagama Y, Kido Y, Adachi E. (Department of Infectious Diseases and Applied Immunology, IMSUT Hospital and Department of Parasitology, Graduate School of Medicine,Osaka City University)

Seroconversion against SARS-CoV-2 occurred after the recovery in patients with COVID-19  
Journal of Medical Virology  September 8, 2020  doi:10.1002/jmv.26495
Yamamoto S, Saito M, Nagai E, Toriuchi K, Nagai H, Yotsuyanagi H, Nakagama Y, Kido Y, Adachi E. (Department of Infectious Diseases and Applied Immunology, IMSUT Hospital and Department of Parasitology, Graduate School of Medicine,Osaka City University)

Professional Commitment to Ethical Discussions Needed From Epidemiologists in the COVID-19 Pandemic
Journal of Epidemiology, 30(9); 375 – 376 2020  doi:10.2188/jea.JE20200278
Kenji Matsui, Keiichiro Yamamoto, Yusuke Inoue. 

SARS-CoV-2 ORF3b Is a Potent Interferon Antagonist Whose Activity Is Increased by a Naturally Occurring Elongation Variant
Cell Reports (online)  September 4, 2020  doi:10.1016/j.celrep.2020.108185
Yoriyuki Konno#, Izumi Kimura#, Keiya Uriu, Masaya Fukushi, Takashi Irie, Yoshio Koyanagi, Daniel Sauter, Robert J. Gifford, USFQ-COVID19 consortium, So Nakagawa, Kei Sato*
(#Equal contribution; *corresponding author)　
Description

Infiltrative Shadows in COVID-19: Pneumonia or Pulmonary Embolism?  
Internal Medicine  August 12, 2020  doi:10.2169/internalmedicine.5380-20
Nagai H, Yamamoto S, Saito M, Adachi E.  (Department of Infectious Diseases and Applied Immunology, IMSUT Hospital)

COVID-19パンデミック下の人工呼吸器トリアージ問題にどう取り組むべきかー学際的協働に向けた医事法学からのアプローチ  *only in Japanese
病院 79(8); 610-616，2020/8．
一家 綱邦, Funabashi Akiko (船橋 亜希子)

対話を通じ共通目標の模索を  *only in Japanese
新聞研究, 827:34-35, 日本新聞協会, 2020/8.
MUTO Kaori (武藤 香織)

Cases of coronavirus disease-2019 in HIV-infected transgender women
AIDS  July 15, 2020  doi:10.1097/QAD.0000000000002573
Adachi E, Saito M, Ikeuchi K, Hoshina T, Yotsuyanagi H.  (Department of Infectious Diseases and Applied Immunology, IMSUT Hospital andThe Jikei University Hospial) 

Relative Bradycardia in Patients with Mild-to-Moderate Coronavirus Disease, Japan  
Emerging infectious diseases  July 1, 2020  doi:10.3201/eid2610.202648 
Ikeuchi K, Saito M, Yamamoto S, Nagai H, Adachi E.  (Department of Infectious Diseases and Applied Immunology, IMSUT Hospital)

Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development
Proc Natl Acad Sci USA (online)  June 22, 2020  doi:10.1073/pnas.2009799117
Masaki Imai, Kiyoko Iwatsuki-Horimoto, Masato Hatta, Samantha Loeber, Peter J. Halfmann, Noriko Nakajima, Tokiko Watanabe, Michiko Ujie, Kenta Takahashi, Mutsumi Ito, Shinya Yamada, Shufang Fan, Shiho Chiba, Makoto Kuroda, Lizheng Guan, Kosuke Takada, Tammy Armbrust, Aaron Balogh, Yuri Furusawa, Moe Okuda, Hiroshi Ueki, Atsuhiro Yasuhara, Yuko Sakai-Tagawa, Tiago J. S. Lopes, Maki Kiso, Seiya Yamayoshi, Noriko Kinoshita, Norio Ohmagari, Shin-ichiro Hattori, Makoto Takeda, Hiroaki Mitsuya, Florian Krammer, Tadaki Suzuki, Yoshihiro Kawaoka. 

The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner
Viruses, 2020 Jun 10;12(6):629. doi:10.3390/v12060629
Mizuki Yamamoto, Maki Kiso, Yuko Sakai-Tagawa, Kiyoko Iwatsuki-Horimoto, Msaki Imai, Makoto Takeda, Noriko Kinoshita, Norio Omagari, Jin Gohda, Kentaro Semba, Zene  Matsuda, Yasushi Kawaguchi, Yoshihiro Kawaoka, Jun-ichiro Inoue.

Japanese citizens' behavioral changes and preparedness against COVID-19: An online survey during the early phase of the pandemic
PLOS ONE, 15(6); e0234292, 2020/6, doi:10.1371/journal.pone.0234292
Kaori Muto, Isamu Yamamoto, Miwako Nagasu, Mikihito Tanaka, Koji Wada. 

Rapid and accurate detection of novel coronavirus SARS-CoV-2 using CRISPR-Cas3
medRxivew  June 2, 2020  doi:10.1101/2020.06.02.20119875
Kazuto Yoshimi, Kohei Takeshita, Seiya Yamayoshi, Satomi Shibumura, Yuko Yamauchi, Masaki Yamamoto, Hiroshi Yotsuyanagi, Yoshihiro Kawaoka, Tomoji Mashimo. 

Transmission of SARS-CoV-2 in Domestic Cats
New England Journal of Medicine (NEJM)  May 13, 2020  doi:10.1056/NEJMc2013400
Peter J. Halfmann, Masato Hatta, Shiho Chiba, Tadashi Maemura, Shufang Fan, Makoto Takeda, Noriko Kinoshita, Shin-ichiro Hattori, Yuko Sakai-Tagawa, Kiyoko Iwatsuki-Horimoto, Masaki Imai, Yoshihiro Kawaoka.

Gargle Lavage as a Safe and Sensitive Alternative to Swab Samples to Diagnose COVID-19: A Case Report in Japan.
Clinical Infectious Diseases  April 2, 2020  doi:10.1093/cid/ciaa377
Saito M, Adachi E, et al. (Department of Infectious Diseases and Applied Immunology, IMSUT Hospital)