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Antibody titers against SARS-CoV-2 decline, but do not disappear for several months

Description

A research group led by Professor Yoshihiro Kawaoka and Associate Professor Seiya Yamayoshi of the Institute of Medical Science, the University of Tokyo (IMSUT) found that antibodies induced by SARS-CoV-2 virus infection can persist for at least 3 to 6 months after onset. They showed that the antibody levels peak on the 20th day after induction and gradually decrease over time, with the rate of decrease slowing over time and allowing the antibodies to persist for a long time. The results of this study were published in "EClinical Medicine"  on February 12, 2021.

Press release (Japanese only)

Published Article

"Antibody titers against SARS-CoV-2 decline, but do not disappear for several months"

EClinicalMedicine Volume 32, February 2021, 100734 doi:10.1016/j.eclinm.2021.100734

Seiya Yamayoshi*, Atsuhiro Yasuhara, Mutsumi Ito, Osamu Akasaka, Morio Nakamura, Ichiro Nakachi, Michiko Koga, Keiko Mitamura, Kazuma Yagi, Kenji Maeda, Hideaki Kato, Masanori Nojima, David Pattinson, Takayuki Ogura, Rie Baba, Kensuke Fujita, Hiroyuki Nagai, Shinya Yamamoto, Makoto Saito, Eisuke Adachi, Junichi Ochi, Shin-ichiro Hattori, Tetsuya Suzuki, Yusuke Miyazato, Shiho Chiba, Moe Okuda, Jurika Murakami, Taiki Hamabata, Kiyoko Iwatsuki-Horimoto, Hideaki Nakajima, Hiroaki Mitsuya, Norio Omagari, Norio Sugaya, Hiroshi Yotsuyanagi, and Yoshihiro Kawaoka*(*corresponding-authers)

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