論文

2021年

  1. Yamaguchi K, Kasajima R, Takane K, Hatakeyama S, Shimizu E, Yamaguchi R, Katayama K, Arai M, Ishioka C, Iwama T, Kaneko S, Matsubara N, Moriya Y, Nomizu T, Sugano K, Tamura K, Tomita N, Yoshida T, Sugihara K, Nakamura Y, Miyano S, Imoto S, Furukawa Y, Ikenoue T. Application of targeted nanopore sequencing for the screening and determination of structural variants in patients with Lynch syndrome. J Hum Genet. 2021 Nov;66(11):1053-1060. doi: 10.1038/s10038-021-00927-9.
  2. Murakami Y, Fukui R, Tanaka R, Motoi Y, Kanno A, Sato R, Yamaguchi K, Amano H, Furukawa Y, Suzuki H, Suzuki Y, Tamura N, Yamashita N, Miyake K. Anti-TLR7 antibody protects against lupus nephritis in NZBWF1 mice by targeting B cells and patrolling monocytes. Frontiers in Immunology. 2021 Nov 11;12:777197. doi:10.3389/fimmu.2021.777197.
  3. Liu X, Yamaguchi K, Takane K, Zhu C, Hirata M, Hikiba Y, Maeda S, Furukawa Y, Ikenoue T. Cancer-associated IDH mutations induce Glut1 expression and glucose metabolic disorders through a PI3K/Akt/mTORC1-Hif1α axis. PLoS One, Sep 13;16(9):e0257090　2021. doi: 10.1371/journal.pone.0257090.
  4. Ishizaka A, Koga M, Mizutani T, Parbie PK, Prawisuda D, Yusa N, Sedohara A, Kikuchi T, Ikeuchi K, Adachi E, Koibuchi T, Furukawa Y, Tojo A, Imoto S, Suzuki Y, Tsutsumi T, Kiyono H, Matano T, Yotsuyanagi H. Unique Gut Microbiome in HIV Patients on Antiretroviral Therapy (ART) Suggests Association with Chronic Inflammation. Microbiol Spectr. 2021 Sep 3;9(1):e0070821. doi: 10.1128/Spectrum.00708-21.
  5. Konishi H, Yamaguchi R, Yamaguchi K, Furukawa Y, Imoto S. Halcyon: an accurate basecaller exploiting an encoder-decoder model with monotonic attention. Bioinformatics. 2021 Jun 9;37(9):1211-1217. doi: 10.1093/bioinformatics/btaa953.
  6. Fujimoto K, Kimura Y, Allegretti JR, Yamamoto M, Zhang YZ, Katayama K, Tremmel G, Kawaguchi Y, Shimohigoshi M, Hayashi T, Uematsu M, Yamaguchi K, Furukawa Y, Akiyama Y, Yamaguchi R, Crowe SE, Ernst PB, Miyano S, Kiyono H, Imoto S, Uematsu S. Functional restoration of bacteriomes and viromes by fecal microbiota transplantation. Gastroenterology. 2021 May;160(6):2089-2102.e12. doi: 10.1053/j.gastro.2021.02.013.
  7. Yasui, R., Sekine, K., Yamaguchi, K., Furukawa, Y. and Taniguchi, H. Robust parameter design of human induced pluripotent stem cell differentiation protocols defines lineage-specific induction of anterior-posterior gut tube endodermal cells. Stem Cells. 2021 Apr;39(4):429-442. doi: 10.1002/stem.3326. PMID: 33400835.
  8. Fujino T, Goyama S, Sugiura Y, Inoue D, Asada S, Yamasaki S, Matsumoto A, Yamaguchi K, Isobe Y, Tsuchiya A, Shikata S, Sato N, Morinaga H, Fukuyama T, Tanaka Y, Fukushima T, Takeda R, Yamamoto K, Honda H, Nishimura E, Furukawa Y, Shibata T, Abdel-Wahab O, Suematsu M, Kitamura T. Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway. Nat Commun, 2021 Mar 23;12(1):1826. doi: 10.1038/s41467-021-22053-y
  9. Suzuki N, Johmura Y, Wang TW, Migita T, Wu W, Noguchi R, Yamaguchi K, Furukawa Y, Nakamura S, Miyoshi I, Yoshimori T, Ohta T, Nakanishi M. TP53/p53-FBXO22-TFEB controls basal autophagy to govern hormesis. Autophagy. 2021 Mar 11:1-18. doi: 10.1080/15548627.2021 Mar 11:1-18. doi: 10.1080/15548627.2021.1897961.
  10. Suzuki M, Kasajima R, Yokose, Ito H, Shimizu E, Hatakeyama S, Yokoyama K, Yamaguchi R, Furukawa Y, Miyano S, Imoto S, Yoshioka E, Washimi K, Okubo Y, Kawachi K, Sato S, Miyagi Y. T Comprehensive molecular analysis of genomic profiles and PD-L1 expression in lung adenocarcinoma with a high-grade fetal adenocarcinoma component. Transl Lung Cancer Res, 10, No 3, 1292-1304. 2021 vol 10, No 3, 1292-1304. doi: 10.21037/tlcr-20-1158
  11. Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M. Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders. Science, 371(6526):265-270. 2021.
  12. Innocenti F, Sibley A, Patil S, Etheridge A, Jiang C, Ou FS, Howell S, Plummer S, Casey G, Bertagnolli M, McLeod H, Auman J, Blanke C, Furukawa Y, Venook A, Kubo M, Lenz HJ, Parker J, Ratain M. Genomic analysis of germline variation associated with survival of colorectal cancer patients treated with chemotherapy plus biologics in CALGB/SWOG 80405 (Alliance). Clin Cancer Res, 27(1):267-275, 2021.
  13. Nakatsuka T, Tateishi K, Kato H, Fujiwara H, Yamamoto K, Kudo Y, Nakagawa H, Tanaka Y, Ijichi H, Ikenoue T, Ishizawa T, Hasegawa K, Tachibana M, Shinkai Y, Koike K. Inhibition of histone methyltransferase G9a attenuates liver cancer initiation by sensitizing DNA-damaged hepatocytes to p53-induced apoptosis. Cell Death Dis, 12(1):99, 2021.
  14. Maeda S, Hikiba Y, Fujiwara H, Ikenoue T, Sue S, Sugimori M, Matsubayashi M, Kaneko H, Irie K, Sasaki T, Chuma M. NAFLD exacerbates cholangitis and promotes cholangiocellular carcinoma in mice. Cancer Sci, 112(4):1471-1480, 2021. doi: 10.1111/cas.14828.
  15. Hayata Y, Nakagawa H, Kurosaki S, Kawamura S, Matsushita Y, Hayakawa Y, Suzuki N, Hata M, Tsuboi M, Kinoshita H, Miyabayashi K, Mizutani H, Nakagomi R, Ikenoue T, Hirata Y, Arita J, Hasegawa K, Tateishi K, Koike K. Axin2+ peribiliary glands in the periampullary region generate biliary epithelial stem cells that give rise to ampullary carcinoma. Gastroenterology, 160(6):2133-2148.e6, 2021. doi: 10.1053/j.gastro.2021.01.028.

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