S. Liu, Y. Maruzuru, K. Takeshima, N. Koyanagi, A. Kato, Y. Kawaguchi. (2024) Impact of the interaction between herpes simplex virus 1 ICP22 and FACT on viral gene expression and pathogenesis. J. Virol. 98: e00737-24.
A. Kato, R. Iwasaki, K. Takeshima, Y. Maruzuru, N. Koyanagi, T. Natsume, H. Kusano, S. Adachi, S. Kawano, Y. Kawaguchi. (2024) Identification of a novel neurovirulence factor encoded by the cryptic orphan gene UL31.6 of herpes simplex virus 1. J. Virol. 98: e00747-24. Editor’s Pickに選出 Link⇒
M. Nobe, Y. Maruzuru, K. Takeshima, N. Koyanagi, A. Kato, Y. Kawaguchi. (2024) MYBBP1A is required for efficient replication and gene expression of herpes simplex virus 1. Microbiol. Immunol. 68: 148-154.
2023
A. Fukui, Y. Maruzuru, S. Ohno, M. Nobe, S. Iwata, K. Takeshima, N. Koyanagi, A. Kato, S. Kitazume, Y. Yamaguchi, Y. Kawaguchi. (2023) Dual impacts of a glycan shield on the envelope glycoprotein B of HSV-1: evasion from human antibodies in vivo and neurovirulence. mBio 14: e00992-23.
A. Fukui, Y. Maruzuru, K. Takeshima, N. Koyanagi, A. Kato, Y. Kawaguchi. (2023) Establishment of a system to quantify wild-type herpes simplex virus-induced cell-cell fusion reveals a role of N-glycosylation of HSV-1 envelope glycoprotein B in cell-cell fusion. Microbiol. Immunol. 67: 114-119.
Y. Kuchitsu, K. Mukai, R. Uematsu, Y. Takaada, A. Shinojima, R. Shindo, T. Shoji, S. Hamano, E. Ogawa, R. Sato, K. Miyake, A. Kato, Y. Kawaguchi, M. Nishitani-Isa, K. Izawa, R. Nishikomori, T. Yasumi, T. Suzuki, N. Dohmae, T. Uemura, G. N. Barber, H. Arai, S. Waguri, T. Taguchi. (2023) STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes. Nat. Cell Biol. 25: 453-466.
J. K. S. Duncan, D. Xu, M. Licursi, M. A. Joyce, H. A. Saffran, K. Liu, J. Gohda, D. L. Tyrrell, Y. Kawaguchi, K. Hirasawa. (2023) Interferon regulatory factor 3 mediates effective antiviral responses to human coronavirus 229E and OC43 infection. Front. Immunol. 14: 930086.
A. H. E. Hassan, S. M. El-Sayed, M. Yamamoto, J. Gohda, T. Matsumoto, M. Shirouzu, J. Inoue, Y. Kawaguchi, R. M. A. Mansour, A. Anvari, A. A. Farahat. (2023) In silico and in vitro evaluation of some amidine derivatives as hit compounds towards development of inhibitors against coronavirus diseases. Viruses 15: 1171.
K. Nagai, Y. Muto, S. Miura, K. Takahashi, Y. Naruse, R. Hiruta, Y. Hashimoto, M. Uzuki, Y. Haga, R. Fujii, K. Ueda, Y. Kawaguchi, M. Fujii, S. Kitazume. (2023) Brain-specific glycosylation enzyme GnT-IX maintains levels of protein tyrosine phosphatase receptor PTPRZ, thereby mediating glioma growth PTPRZ glycosylation regulates glioma growth. J. Biol. Chem. 299: 105128.
K. Takahashi, K. Kanekiyo, K. Sakuda, Y. Muto, M. Iguchi, N. Matsuda, Y. Hashimoto, K. Kanai, H. Ogawa, H. Hirase, A. Kakita, N. Bizen, H. Takebayashi, Y. Kawaguchi, M. Uzuki, S. Kitazume. (2023) Brain-specific glycosylation of protein tyrosine phosphatase receptor type Z (PTPRZ) marks a demyelination-associated astrocyte subtype. J. Neurochem. 166: 547-559.
2022
K. Takeshima, Y. Maruzuru, N. Koyanagi, A. Kato, Y. Kawaguchi. (2022) Redundant and specific roles of A-type lamins and lamin B receptor in herpes simplex virus 1 infection. J. Virol. 96: e01429-22.
F. Maeda, A. Kato, K. Takeshima, M. Shibazaki, R. Sato, T. Shibata, K. Miyake, H. Kozuka-Hata, M. Oyama, E. Shimizu, S. Imoto, S. Miyano, S. Adachi, T. Natsume, K. Takeuchi, Y. Maruzuru, N. Koyanagi, J. Arii, Y. Kawaguchi. (2022) Role of the orphan transporter SLC35E1 in the nuclear egress of herpes simplex virus 1. J. Virol. 96: e00306-22.
J. Arii, K. Takeshima, Y. Maruzuru, N. Koyanagi, Y. Nakayama, A. Kato, Y. Mori and Y. Kawaguchi. (2022) Role of the arginine cluster in the disordered domain of Herpes Simplex Virus 1 UL34 for the recruitment of ESCRT-III for viral primary envelopment. J. Virol. 96: e01704-21.
H. Ogura, J. Gohda, X. Lu, M. Yamamoto, Y. Takesue, A. Son, S. Doi, K. Matsushita, F. Isobe, Y. Fukuda, T. Huang, T. Ueno, N. Mambo, H. Murakami, Y. Kawaguchi, J. Inoue, K. Shirai, S. Yamasaki, J. Hirata, S. Ishido. (2022) Dysfunctional Sars-CoV-2 M protein-specific cytotoxic T lymphocytes in patients recovering from severe COVID-19. Nat. Commun. 13: 7063.
M. Yamamoto, J. Gohda, A. Kobayashi, K. Tomita, Y. Hirayama, N. Koshikawa, M. Seiki, K. Semba, T. Akiyama, Y. Kawaguchi and J. Inoue. (2022) Metalloproteinase-dependent and 1 TMPRSS2-independnt cell surface entry pathway of SARS-CoV-2 requires the furin-cleavage site and the S2 domain of spike protein. mBio 13: e00519-22.
Y. Tachida, S. Miura, Y. Muto, H. Takuwa, N. Sahara, A. Shindo, Y. Matsuba, T. Saito, N. Taniguchi, Y. Kawaguchi, H. Tomimoto, T. Saido, S. Kitazume. (2022) Endothelial expression of human amyloid precursor protein leads to amyloid β in the blood and induces cerebral amyloid angiopathy in knock-in mice. J. Biol. Chem. 298: 101880.
Y. Inayoshi, S. Oguro, E. Tanahashi, Z. Lin, Y. Kawaguchi, T. Kodama, C. Sasakawa. (2022) Bacterial artificial chromosome-based reverse genetics system for cloning and manipulation of the full-length genome of infectious bronchitis virus. Curr. Res. Microb. Sci. 3: 100155.
2021
Y. Maruzuru, N. Koyanagi, A. Kato, and Y. Kawaguchi. (2021) Role of the DNA binding activity of herpes simplex virus 1 VP22 in evading AIM2-dependent inflammasome activation induced by the virus. J. Virol. 95: e02172-20.
M. Watanabe, J. Arii, K. Takeshima, A. Fukui, M. Shimojima, H. Kozuka-Hata, M. Oyama, T. Minamitani, T. Yasui, Y. Kubota, M. Takekawa, I. Kosugi, Y. Maruzuru, N. Koyanagi, A. Kato, Y. Mori, and Y. Kawaguchi. (2021) Prohibitin-1 contributes to the cell-to-cell transmission of herpes simplex virus 1 via the MAPK/ERK signaling pathway. J. Virol. 95: e01413-20.
A. Adachi, T. Honda, T. Dainichi, G. Egawa, Y. Yamamoto, T. Nomura, S. Nakajima, A. Otsuka, M. Maekawa, N. Mano, N. Koyanagi, Y. Kawaguchi, T. Ohteki, T. Nagasawa, K. Ikuta, A. Kitoh, and K. Kabashima. (2021) Prolonged high-intensity exercise induces fluctuating immune responses to herpes simplex virus infection via glucocorticoids. J. Allergy Clin. Immunol. 148: 1575-1588.
Y. Hayashi, H. Suzuki, W. Nakajima, I. Uehara, A. Tanimura, T. Himeda, S. Koike, T. Katsuno, S. Kitajiri, N. Koyanagi, Y. Kawaguchi, K. Onomoto, H. Kato, M. Yoneyama, T. Fujita, N. Tanaka. (2021) Virus-infection in cochlear supporting cells induces audiosensory receptor hair cell death by TRAIL-induced necroptosis. PLoS One 16: e0260443.
M. Kandeel, M. Yamamoto, B. K. Park, A. AI-Taher, A. Watanabe, J. Gohda, Y. Kawaguchi, K. Oh-hashi, H. Kwon and J. Inoue. (2021) Discovery of new potent anti-MERS CoV fusion inhibitors. Front. Pharmacol. 12: 685161.
M. Kandeel, M. Yamamoto, H. Tani, A. Kobayashi, J. Gohda, Y. Kawaguchi, B. K. Park, H. Kwon, J. Inoue, A. Alkattan. (2021) Discovery of New Fusion Inhibitor Peptides against SARS-CoV-2 by Targeting the Spike S2 Subunit. Biomol. Ther. 29: 282-289.
2020
A. Kato, S. Adachi, S. Kawano, K. Takeshima, M. Watanabe, S. Kitazume, R. Sato, H. Kusano, N. Koyanagi, Y. Maruzuru, J. Arii, T. Hatta, T. Natsume, and Y. Kawaguchi. (2020) Identification of a Herpes Simplex Virus 1 Gene Encoding Neurovirulence Factor by Chemical Proteomics. Nat. Commun. 11: 4894. プレスリリース/解説 Link⇒
J. Arii, A. Fukui, Y. Shimanaka, N. Kono, H. Arai, Y. Maruzuru, N. Koyanagi, A. Kato, Y. Mori and Y. Kawaguchi. (2020) Role of phosphatidylethanolamine biosynthesis in herpes simplex virus 1 infected cells on progeny virus morphogenesis in the cytoplasm and on viral pathogenicity in vivo. J. Virol. 94: e01572-20. Spotiightとして巻頭で紹介 Link⇒
M. Shibazaki, A. Kato, K. Takeshima, J. Ito, M. Suganami, N. Koyanagi, Y. Maruzuru, K. Sato and Y. Kawaguchi. (2020) Phosphoregulation of a conserved herpesvirus tegument protein by a virally encoded protein kinase in viral pathogenicity and potential linkage between its evolution and viral phylogeny. J. Virol. 94: e01055-20.
J. Arii, F. Maeda, Y. Maruzuru, N. Koyanagi, A. Kato, Y. Mori and Y. Kawaguchi. (2020) ESCRT-III controls nuclear envelope deformation induced by progerin. Sci. Rep. 10: 18877.
N. Koyanagi and Y. Kawaguchi. (2020) Evasion of the cell-mediated immune response by alphaherpesviruses. Viruses 12: 1354.
M. Moriyama, M. Nagai, Y. Maruzuru, T. Koshiba, Y. Kawaguchi, T. Ichinohe. (2020) Influenza virus-induced oxidized DNA activates inflammasomes. iScience 23: 101270.
M. Yamamoto, T. Ichinohe, A. Watanabe, A. Kobayashi, R. Zhang, J. Song, Y. Kawaguchi, Z. Matsuda and J. Inoue. (2020) The antimalarial compound atovaquone inhibits zika and dengue virus infection by blocking E protein-mediated membrane fusion. Viruses 12: 1475.
M. Yamamoto, M. Kiso, Y. Sakai-Tagawa, K. Iwatsuki-Horimoto, M. Imai, M. Takeda, N. Kinoshita, N. Ohmagari, J. Gohda, K. Semba, Z. Matsuda, Y. Kawaguchi, Y. Kawaoka, J. Inoue. (2020) The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner. Viruses 12: 629.
S. Shirahama, R. Onoguchi-Mizutani, K. Kawata, K. Taniue, A. Miki, A. Kato, Y. Kawaguchi, R. Tanaka, T. Kaburaki, H. Kawashima, Y. Urade, M. Aihara, N. Akimitsu. (2020) Long noncoding RNA U90926 is crucial for herpes simplex virus type 1 proliferation in murine retinal photoreceptor cells. Sci. Rep. 10: 19406.
Y. Hayashi, H. Suzuki, W. Nakajima, I. Uehara, A. Tanimura, T. Himeda, S. Koike, T. Katsuno, S. Kitajiri, N. Koyanagi, Y. Kawaguchi, K. Onomoto, H. Kato, M. Yoneyama, T. Fujita, N. Tanaka. (2020) Cochlear supporting cells function as macrophage-like cells and protect audiosensory receptor hair cells from pathogens. Sci. Rep. 10: 6740.
2019
K. Takeshima, J. Arii, Y. Maruzuru, N. Koyanagi, A. Kato and Y. Kawaguchi. (2019) Identification of the Capsid Binding Site in the Herpes Simplex Virus 1 Nuclear Egress Complex and Its Role in Viral Primary Envelopment and Replication. J. Virol. 93: e01290-19.
J. Arii, K. Takeshima, Y. Maruzuru, N. Koyanagi, A. Kato, Y. Kawaguchi. (2019) Roles of the Interhexamer Contact Site for Hexagonal Lattice Formation of Herpes Simplex Virus 1 Nuclear Egress Complex in Viral Primary Envelopment and Replication. J. Virol. 93: e00498-19.
S. Joo, A. Suwanto, A. Sato, R. Nakahashi-Ouchida, H. Mori, Y. Uchida, S. Sato, Y. Kurashima, Y. Yuki, K. Fujihashi, Y. Kawaguchi & H. Kiyono. (2019) A role for the CCR5–CCL5 interaction in the preferential migration of HSV-2-specific effector cells to the vaginal mucosa upon nasal immunization. Mucosal Immunol. 12: 1391-1403.
M. Yamamoto, Q. Du, J. Song, H. Wang, A. Watanabe, Y. Tanaka, Y. Kawaguchi, J.I. Inoue and Z. Matsuda. (2019) Cell-cell and virus-cell fusion assay-based analyses of alanine insertion mutants in the distal α9 portion of the JRFL gp41 subunit from HIV-1. J. Biol. Chem. 294: 5677-5687.
T. Watanabe, N. Suzuki, K. Tomonaga, H. Sawa, Y. Matsuura, Y. Kawaguchi, H. Takahashi, K. Nagasaki, Y. Kawaoka. (2019) Neo-virology: The raison d’etre of viruses. Virus Res. 274: 197751.
2018
Y. Maruzuru, T. Ichinohe, R. Sato, K. Miyake, T. Okano, T. Suzuki, T. Koshiba, N. Koyanagi, S. Tsuda, M. Watanabe, J. Arii, A. Kato, and Y. Kawaguchi. (2018) Herpes Simplex Virus 1 VP22 Inhibits AIM2-dependent Inflammasome Activation to Enable Efficient Viral Replication. Cell Host & Microbe 23: 254-265. プレスリリース/解説 Link⇒
J. Arii, M. Watanabe, F. Maeda, N. Tokai-Nishizumi, T. Chihara, M. Miura, Y. Maruzuru, N. Koyanagi, A. Kato and Y. Kawaguchi. (2018) ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity. Nat. Commun. 9: 3379. プレスリリース/解説 Link⇒
R. Sato,* A. Kato,* T. Chimura, S.-I. Saitoh, T. Shibata, Y. Murakami, R. Fukui, K. Liu, Y. Zhang, J. Arii, G.-H. Sun-Wada, Y. Wada, T. Ikenoue, G. N Barber, T. Manabe, Y. Kawaguchi,** and K. Miyake.** (2018) Combating herpesvirus encephalitis by potentiating a TLR3-mTORC2 axis. Nat. Immunol. 19: 1071-1082. 解説 Link⇒
*Co-first authors, **Co-corresponding authors
A. Kato, S. Oda, M. Watanabe, M. Oyama, H. Kozuka-Hata, N. Koyanagi, Y. Maruzuru, J. Arii, and Y. Kawaguchi. (2018) Roles of the Phosphorylation of Herpes Simplex Virus 1 UL51 at a Specific Site in Viral Replication and Pathogenicity. J. Virol. 92: e01035-18.
N. Koyanagi, A. Kato, K. Takeshima, Y. Maruzuru, H. Kozuka-Hata, M. Oyama, J. Arii, and Y. Kawaguchi. (2018) Regulation of Herpes Simplex Virus 2 Protein Kinase UL13 by Phosphorylation and Its Role in Viral Pathogenesis. J. Virol. 92: e00807-18.
Y. Kawaguchi, Y. Mori and H. Kimura. (2018) Human herpesviruses. Adv. Exp. Med. Biol. (Springer Nature) Vol. 1045.
A. Kato and Y. Kawaguchi. (2018) Us3 protein kinase encoded by HSV: the precise function and mechanism on viral life cycle. Adv. Exp. Med. Biol. (Springer Nature) Vol. 1045: 45-62. Human herpesviruses. Y. Kawaguchi et al., (Eds).
J. Arii and Y. Kawaguchi. (2018) The Role of Herpes Simplex Virus Glycoproteins in Mediating Cell Entry. Adv. Exp. Med. Biol. (Springer Nature) Vol. 1045: 3-21. Human herpesviruses. Y. Kawaguchi et al., (Eds).
D. Liu, H. Wang, M. Yamamoto, J. Song, R. Zhang, Q. Du, Y. Kawaguchi, J. Inoue and Z. Matsuda. (2018) Six-helix bundle completion in the distal C-terminal heptad repeat region of gp41 is required for efficient human immunodeficiency virus type 1 infection. Retrovirology 15:27.
J. Gohda, K. Suzuki, L. Kai, X. Xie, H. Takeuchi, J. Inoue, Y. Kawaguchi, and T. Ishida. (2018) BI-2536 and BI-6727, dual Polo-like kinase / bromodomain inhibitors, effectively reactivate latent HIV-1. Sci. Rep. 8: 3521.
2017
N. Koyanagi, T. Imai, K. Shindo, A. Sato, W. Fujii, T. Ichinohe, N. Takemura, S. Kakuta, S. Uematsu, H. Kiyono, Y. Maruzuru, J. Arii, A. Kato and Y. Kawaguchi. (2017) Herpes simplex virus-1 evasion of CD8+ T cell accumulation contributes to viral encephalitis. J. Clin. Invest. 127: 3784-3795. プレスリリース/解説 Link⇒
R. Kobayashi, A. Kato, H. Sagara, M. Watanabe, Y. Maruzuru, N. Koyanagi, J. Arii and Y. Kawaguchi. (2017) Herpes Simplex Virus 1 Small Capsomere-Interacting Protein VP26 Regulates Nucleocapsid Maturation. J. Virol. 91: e01068-17.
F. Maeda, J. Arii, Y. Hirohata, Y. Maruzuru, N. Koyanagi, A. Kato and Y. Kawaguchi. (2017) Herpes Simplex Virus 1 UL34 Protein Regulates the Global Architecture of the Endoplasmic Reticulum in Infected Cells. J. Virol. 91: e00271-17.
Y. Inoue, T. Saga, T. Aikawa, M. Kumagai, A. Shimada, Y. Kawaguchi, K. Naruse, S. Morishita, A. Koga and H. Takeda. (2017) OPEN Complete fusion of a transposon and herpesvirus created the Teratorn mobile element in medaka fish. Nat. Commun. 8:551.
R. Akkina, H. Ellerbrok, W. Hall, H. Hasegawa, Y. Kawaguchi, H. Kleanthous, E. McSweegan, N. Mercer, V. Romanowski, H. Sawa, A. Vahlne. (2017) 2016 International meeting of the Global Virus Network. Antiviral Res. 142: 21-29.
2016
J. Arii, K. Shindo, N. Koyanagi, A. Kato and Y. Kawaguchi. (2016) Multiple Roles of the Cytoplasmic Domain of Herpes Simplex Virus 1 Envelope Glycoprotein D in Infected Cells. J. Virol. 90: 10170-10181.
S. Oda, J. Arii, N. Koyanagi, A. Kato, and Y. Kawaguchi. (2016) The Interaction between Herpes Simplex Virus 1 Tegument Proteins UL51 and UL14 and Its Role in Virion Morphogenesis. J. Virol. 90: 8754-8767.
Y. Maruzuru, N. Koyanagi, N. Takemura, S. Uematsu, D. Matsubara, Y. Suzuki, J. Arii, A. Kato and Y. Kawaguchi. (2016) p53 is a Host Cell Regulator during Herpes Simplex Encephalitis. J. Virol. 90: 6738-6745.
A. Kato, T. Ando, S. Oda, M. Watanabe, N. Koyanagi, J. Arii and Y. Kawaguchi. (2016) Roles of Us8A and its Phosphorylation Mediated by Us3 in Herpes Simplex Virus 1 Pathogenesis. J. Virol. 90: 5622-5635.
Y. Sato, A. Kato, Y. Maruzuru, M. Oyama, H. Kozuka-Hata, J. Arii and Y. Kawaguchi. (2016) Cellular Transcriptional Coactivator RanBP10 and Herpes Simplex Virus 1 ICP0 Interact and Synergistically Promote Viral Gene Expression and Replication. J. Virol. 90: 3173-3186.
K. Shindo, A. Kato, N. Koyanagi, H. Sagara, J. Arii, and Y. Kawaguchi. (2016) Characterization of a herpes simplex virus 1 (HSV-1) chimera in which the Us3 protein kinase gene is replaced with the HSV-2 Us3 gene. J. Virol. 90: 457-473.
Y. Sato, A. Kato, J. Arii, N. Koyanagi, H. Kozuka-Hata, M. Oyama and Y. Kawaguchi. (2016) Ubiquitin-Specific Protease 9X in Host Cells Interacts with Herpes Simplex Virus 1 ICP0. J. Vet. Med. Sci. 78: 405-410.
N. Maeda, A. Furukawa, K. Kakita, M. Anada, S. Hashimoto, S. Matsunaga, K. Kuroki, T. Ose, A. Kato, J. Arii, Y. Kawaguchi, H. Arase, and K. Maenaka. (2016) Rapid screening by cell-based fusion assay for identifying novel antivirals of glycoprotein B-mediated herpes simplex virus type 1 infection. Biol. Pharm. Bull. 39: 1897-1902.
M. Yamamoto, S. Matsuyama, X. Li, M. Takeda, Y. Kawaguchi, J. Inoue, Z. Matsuda. (2016) Identification of Nafamostat as a Potent Inhibitor of Middle East Respiratory Syndrome Coronavirus S Protein-Mediated Membrane Fusion Using the Split-Protein-Based Cell-Cell Fusion Assay. Antimicrobial Agents and Chemotherapy 60: 6532-6539.
2015
Z. Liu, A. Kato, M. Oyama, H. Kozuka-Hata, J. Arii, and Y. Kawaguchi. (2015) Role of Host Cell p32 in Herpes Simplex Virus 1 De-envelopment During Viral Nuclear Egress. J. Virol. 89: 8982-8998. Spotiightとして巻頭で紹介 Link⇒
Y. Hirohata, J. Arii, Z. Liu, K. Shindo, M. Oyama, H. Kozuka-Hata, H. Sagara, A. Kato, and Y. Kawaguchi. (2015) Herpes simplex virus 1 recruits CD98 heavy chain and β1 integrin to the nuclear membrane for viral de-envelopment. J. Virol. 89: 7799-7812.
R. Kobayashi, A. Kato, S. Oda, N. Koyanagi, M. Oyama, H. Kozuka-Hata, J. Arii, and Y. Kawaguchi. (2015) Function of the Herpes Simplex Virus 1 Small Capsid Protein VP26 is Regulated by Phosphorylation at a Specific Site. J. Virol. 89: 6141-6147.
J. Arii, Y. Hirohata, A. Kato and Y. Kawaguchi. (2015) Nonmuscle Myosin Heavy Chain IIB Mediates Herpes Simplex Virus 1 Entry. J. Virol. 89: 1879-1888.
A. Kato, J. Arii, Y. Koyanagi, and Y. Kawaguchi. (2015) Phosphorylation of Herpes Simplex Virus 1 dUTPase Regulates Viral Virulence and Genome Integrity by Compensating for Low Cellular dUTPase Activity in the Central Nervous System. J. Virol. 89: 241-248.
Y. Hirohata, A. Kato, M. Oyama, H. Kozuka-Hata, N. Koyanagi, J. Arii and Y. Kawaguchi. (2015) Interactome Analysis of Herpes Simplex Virus 1 Envelope Glycoprotein H. Microbiol. Immunol. 59: 331-337.
2014
H. Fujii, A. Kato, M. Mugitani, Y. Kashima, M. Oyama, H. Kozuka-Hata, J. Arii, and Y. Kawaguchi. (2014) The UL12 Protein of Herpes Simplex Virus 1 Is Regulated by Tyrosine Phosphorylation. J. Virol. 88: 10624-10634.
A. Kato, Y. Hirohata, J. Arii, and Y. Kawaguchi. (2014) Phosphorylation of Herpes Simplex Virus 1 dUTPase Up-regulated Viral dUTPase Activity to Compensate for Low Cellular dUTPase Activity for Efficient Viral Replication. J. Virol.88: 7776-7785.
Y. Maruzuru, K. Shindo, Z. Liu, M. Oyama, H. Kozuka-Hata, J. Arii, A. Kato and Y. Kawaguchi. (2014) The Role of Herpes Simplex Virus 1 Immediate-Early Protein ICP22 in Viral Nuclear Egress. J. Virol. 88: 7445-7454.
Z. Liu, A. Kato, K. Shindo, T. Noda, H. Sagara, Y. Kawaoka, J. Arii, and Y. Kawaguchi. (2014) Herpes simplex virus 1 UL47 interacts with viral nuclear egress factors UL31, UL34 and Us3, and regulates viral nuclear egress. J. Virol. 88: 4657-4667.
A. Kato, K. Shindo, Y. Maruzuru, and Y. Kawaguchi. (2014) Phosphorylation of a herpes simplex virus 1 dUTPase by a viral protein kinase Us3 dictates viral pathogenicity in the central nervous system but not at the periphery. J. Virol.88: 2775-2785. (Faculty of 1000 Biologyで 'Very Good' の評価)
H. Fujii, M. Mugitani, N. Koyanagi, Z. Liu, S. Tsuda, J. Arii, A. Kato and Y. Kawaguchi.(2014) Role of the Nuclease Activities Encoded by Herpes Simplex Virus 1 UL12 in Viral Replication and Neurovirulence. J. Virol. 88: 2359-2364.
A. Kato, S. Tsuda, Z. Liu, H. Kozuka-Hata, M. Oyama and Y. Kawaguchi.(2014) Herpes simplex virus 1 protein kinase Us3 phosphorylates viral dUTPase and regulates its catalytic activity in infected cells. J. Virol. 88: 655-666.
N. Koyanagi, T. Imai, J. Arii, A. Kato and Y. Kawaguchi. (2014) Roles of herpes simplex virus 1 Us3 in viral neuroinvasiveness. Microbiol. Immunol. 58: 31-37.
K. Imamura, N. Imamachi, G. Akizuki, M. Kumakura, A. Kawaguchi, K. Nagata, A. Kato, Y. Kawaguchi, H. Sato, M. Yoneda, C. Kai, T. Yada, Y. Suzuki, T. Yamada, T. Ozawa, K. Kaneki, T. Inoue, M. Kobayashi, T. Kodama, Y. Wada, K. Sekimizu, N. Akimitsu. (2014) Long noncoding RNA NEAT1-dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli. Mol. Cell 53: 393-406.
A. Sato, A. Suwanto, M. Okabe, S. Sato, T. Nochi, T. Imai, N. Koyanagi, J. Kunisawa, Y. Kawaguchi and H. Kiyono. (2014) Vaginal memory T cells induced by intranasal vaccination are critical for protective T cell recruitment and prevention of genital HSV-2 disease. J. Virol. 88: 13699-13708.
2013
Y. Maruzuru, H. Fujii, M. Oyama, H. Kozuka-Hata, A. Kato and Y. Kawaguchi. (2013) Roles of p53 in herpes simplex virus 1 replication. J. Virol. 87: 9323-9332.
T. Imai, N. Koyanagi, R. Ogawa, K. Shindo, T. Suenaga, A. Sato, J. Arii, A. Kato, H. Kiyono, H. Arase, and Y. Kawaguchi. (2013) Us3 Kinase encoded by Herpes Simplex Virus 1 Mediates Downregulation of Cell Surface Major Histocompatibility Complex Class I and Evasion of CD8+ T cells. PLoS One 8: e72050
Y. Kawaguchi. (2013) Us3, a Multi-Functional Protein kinase Encoded by Herpes Simplex Virus 1:How does it Function In Vivo? Cornea 32: S22-S27.
V. L. Sage, M. Jung, J. D. Alter, E. G. Wills, S. M. Johnston, Y. Kawaguchi, J. D. Baines and B. W. Banfield. (2013) The Herpes Simplex Virus Type 2 UL21 Protein is Essential for Virus Propagation. J. Virol. 87: 5904-5915.
2012
M. Tanaka, A. Kato, Y. Satoh, T. Ide, K. Sagou, K. Kimura, H. Hasegawa and Y. Kawaguchi. (2012) Herpes Simplex Virus 1 VP22 Regulates Translocation of Multiple Viral and Cellular Proteins and Promotes Neurovirulence. J. Virol. 86: 5264-5277. (Faculty of 1000 Biologyで 'Must Read' の評価)
2011
A. Kato, Z. Liu, A. Minowa, T. Imai, M. Tanaka, K. Sugimoto, Y. Nishiyama, J. Arii, and Y. Kawaguchi. (2011) Herpes Simplex Virus 1 Protein Kinase Us3 and Major Tegument Protein UL47 Reciprocally Regulate Their Subcellular Localization in Infected Cells. J. Virol. 85: 9599-9613. (Faculty of 1000 Biologyで 'Recommended' の評価)
T. Imai, J. Arii, A. Minowa, A. Kakimoto, N. Koyanagi, A. Kato and Y. Kawaguchi. (2011) Role of the Herpes Simplex Virus 1 Us3 Kinase Phosphorylation Site and Endocytosis Motifs in Envelope Glycoprotein B in Its Intracellular Transport and Neurovirulence. J. Virol. 85: 5003-5015. (Faculty of 1000 Biologyで 'Must Read' の評価)
P. Gee, Y. Ando, H. Kitayama, S. Yamamoto, Y. Kanemura, H. Ebina, Y. Kawaguchi and Y. Koyanagi. (2011) APOBEC1-mediated editing and attenuation of HSV-1 DNA implicates an antiviral role in neurons during encephalitis. J. Virol. 85: 9726-9736.
T. W. Wisner, K. Sugimoto, P. Howard, Y. Kawaguchi and D. C. Johnson. (2011) Anterograde transport of herpes simplex virus capsids in neurons by Separate and Married mechanisms. J. Virol. 85: 5919-5928.
2010
J. Arii, H. Goto, T. Suenaga, M. Oyama, H. Kozuka-Hata, T. Imai, A. Minowa, H. Akashi, H. Arase, Y. Kawaoka and Y. Kawaguchi. (2010) Non-muscle myosin IIA is a functional entry receptor for herpes simplex virus 1. Nature 467: 859-862. (Faculty of 1000 Biologyで 'Must Read' の評価)プレスリリース/解説 Link⇒
J. Arii, J. Wang, T. Morimoto, T. Suenaga, H. Akashi, H. Arase, and Y. Kawaguchi. (2010) A Single Amino Acid Substitution in Herpes simplex virus 1 Envelope Glycoprotein B at a Site Required for Binding to the Paired Immunoglobulin-like Type 2 Receptor a (PILRa) Abrogates PILRa-dependent Viral Entry and Reduces Pathogenesis. J. Virol. 84: 10773-10783.
K. Sagou, M. Uema and Y. Kawaguchi. (2010) Nucleolin is required for efficient nuclear egress of herpes simplex virus 1 nucleocapsids. J. Virol. 84: 2110-2121.
T. Imai, K. Sagou, J. Arii and Y. Kawaguchi. (2010) Effects of Phosphorylation of Herpes Simplex Virus 1 Envelope Glycoprotein B by Us3 Kinase In Vivo and In Vitro. J. Virol. 84: 153-162.
T. Suenaga, T. Satoh, P. Somboonthum, Y. Kawaguchi, Y. Mori, and H. Arase. (2010) Myelin-associated glycoprotein mediates membrane fusion and entry of neurotropic herpesviruses. Proc. Natl. Acad. Sci. USA107: 866-871.
K. Gotoh, Y. Tanaka, A. Nishikimi, R. Nakamura, H. Yamada, N. Maeda, T. Ishikawa, K. Hoshino, T. Uruno, Q. Cao, S. Higashi, Y. Kawaguchi, M. Enjoji, R. Takayanagi, T. Kaisho, Y. Yoshikai, and Y. Fukui. (2010) Selective control of type I IFN induction by the Rac activator DOCK2 during TLR–mediated plasmacytoid dendritic cell activation. J. Exp. Med. 207: 721-730.
W. Azab, K. Tsujimura, K. Kato, J. Arii, T. Morimoto, Y. Kawaguchi, Y. Tohya, T. Matsumura and H. Akashi. (2010) Characterization of a thymidine kinase-deficient mutant of equine herpesvirus 4 and in vitro susceptibility of the virus to antiviral agents. Antiviral Res. 85: 389-395.
2009
T. Morimoto, J. Arii, M. Tanaka, T. Sata, H. Akashi, M. Yamada, Y. Nishiyama, M. Uema and Y. Kawaguchi. (2009) Differences in the Regulatory and Functional Effects of the Us3 Protein Kinase Activities of Herpes Simplex Virus 1 and 2. J. Virol. 83: 11624-11634.
K. Sagou, T. Imai, H. Sagara, M. Uema, and Y. Kawaguchi. (2009) Regulation of the Catalytic Activity of Herpes Simplex Virus 1 Protein Kinase Us3 by Auto-Phosphorylation and Its Role in Pathogenesis. J. Virol. 83: 5773-5783.
J. Arii, M. Uema, T. Morimoto, H. Sagara, H. Akashi, E. Ono, H. Arase, and Y. Kawaguchi. (2009) Entry of herpes simplex virus 1 and other alphaherpesviruses via the paired immunoglobulin-like type 2 receptor a. J. Virol. 83:4520-4527. Spotiightとして巻頭で紹介 Link⇒
A. Kato, J. Arii, I. Shiratori, H. Akashi, H. Arase and Y. Kawaguchi. (2009) Herpes simplex virus 1 protein kinase Us3 phosphorylates viral envelope glycoprotein B and regulates its expression on the cell surface. J. Virol. 83: 250-261. (Faculty of 1000 Biologyで 'Must Read' の評価)
R. Asai, A. Kato and Y. Kawaguchi. (2009) Epstein-Barr Virus Protein Kinase BGLF4 Interacts with Viral Transactivator BZLF1 and Regulates Its Transactivation Activity. J. Gen. Virol. 90: 1575-1581.
J. Wang, F. Fan, T. Satoh, J. Arii, L. L. Lanier, P. G. Spear, Y. Kawaguchi, H. Arase. (2009) Binding of herpes simplex virus glycoprotein B (gB) to PILRa depends on specific sialylated O-linked glycans on gB. J. Virol. 83: 13042-13045.
T. W. Wisner, C. C. Wright, A. Kato, Y. Kawaguchi, F. Mou, J. D. Baines, R. J. Roller, and D. C. Johnson. (2009) Herpesvirus gB-induced fusion between the virion envelope and outer nuclear membrane during virus egress is regulated by the viral US3 kinase. J. Virol. 83: 3115-3126.
T. Morimoto, J. Arii, H. Akashi and Y. Kawaguchi. (2009) Identification of multiple sites in herpes simplex virus genomes suitable for insertion of foreign genes. Microbiol. Immunol. 53: 155-161.
H. Konno, T. Yamamoto, K. Yamazaki, J. Gohda, T. Akiyama, K. Semba, H. Goto, A. Kato, T. Yujiri, T. Imai, Y. Kawaguchi, B. Su, O. Takeuchi, S. Akira, Y. Tsunetsugu-Yokota, and J. Inoue. (2009) TRAF6 establishes innate immune responses by activating NF-kB and IRF7 upon sensing cytosolic viral RNA and DNA. PLoS ONE 4: e5674.
J. Arii, K. Kato, Y. Kawaguchi, Y. Tohya, H. Akashi. (2009) Analysis of herpesvirus host specificity determinants using herpesvirus genomes as bacterial artificial chromosomes. Microbiol. Immunol. 53: 433-441.
T. Nojima, T. Oshiro-Ideue, H. Nakanoya, H. Kawamura, T. Morimoto, Y. Kawaguchi, N. Kataoka,, M. Hagiwara. (2009) Herpesvirus protein ICP27 switches PML isoform by altering mRNA splicing. Nucleic Acids Res. 37: 6515-6527.
2008
A. Kato, M. Tanaka, M. Yamamoto, R. Asai, T. Sata, Y. Nishiyama and Y. Kawaguchi. (2008) Identification of a physiological phosphorylation site of the Herpes simplex virus 1-encoded protein kinase Us3 which regulates its optimal catalytic activity in vitro and influences its function in infected cells. J. Virol. 82: 6172-6189.
K. Sugimoto, M. Uema, H. Sagara, M. Tanaka, T. Sata, Y. Hashimoto, and Y. Kawaguchi. (2008) Simultaneous Tracking of Capsid, Tegument and Envelope Protein Localization in Living Cells Infected with Triple Fluorescent Herpes Simplex Virus 1. J. Virol. 82: 5198-5211. Spotiightとして巻頭で紹介 Link⇒
T. Satoh, J. Arii, T. Suenaga, J. Wang, A. Kogure, J. Uehori, N. Arase, I. Shiratori, S. Tanaka, Y. Kawaguchi, P. G. Spear, L. L. Lanier and H. Arase. (2008) PILRa is a herpes simplex-1 entry co-receptor that associates with glycoprotein B. Cell 132: 1-10.
Y. Orihara, H. Hamamoto, H. Kasuga, T. Shimada, Y. Kawaguchiand K. Sekimizu. (2008) Evaluation of therapeutic effects of antiviral agents using a silkworm baculovirus infection model. J. Gen. Virol. 89: 188-194.
Y. Ando, H. Kitayama, Y. Kawaguchi and Y. Koyanagi. Primary target cells of herpes simplex virus type 1 in the hippocampus. Microbes and Infection 10: 1514-1523.
Kamakura, M., Nawa, A., Ushijima, Y., Goshima, F., Kawaguchi, Y., Kikkawa, F., Nishiyama, Y. (2008) Microarray analysis of transcriptional responses to infection by herpes simplex virus types 1 and 2 and their US3-deficient mutants. Microbes and Infection 10: 405-413.
M. Tanaka, T. Sata and Y. Kawaguchi. (2008) The product of UL7 gene of herpes simplex virus type 1 interacts with a mitochondria protein, adenine nucleotide translocator 2. Virology J. 5: 125-137.
2007
S. Iwahori, N. Shirata, Y. Kawaguchi, S. K. Weller, Y. Sato, A. Kudoh, S. Nakayama, H. Isomura, and T. Tsurumi. (2007) Enhanced Phosphorylation of Transcription Factor Sp1 dependent on Ataxia Telangiectasia-Mutated (ATM) in response to Herpes Simplex Virus Type I Infection. J. Virol. 81: 9653-9664.
R. Asai, T. Ohno, A. Kato and Y. Kawaguchi. (2007) Identification of proteins directly phosphorylated by UL13 protein kinase from herpes simplex virus 1. Microbes and Infection 9: 1434-1438.
T. Koshizuka, Y. Kawaguchi, N. Nozawa, I. Mori, and Y. Nishiyama. (2007) Herpes simplex virus protein UL11 but not UL51 is associated with lipid rafts. Virus Genes 35: 571-575.
Y. F. Chiu, C. P. Tung, Y. H. Lee, W. H. Wang, C. Li, J. Y. Hung, C. Y. Wang, Y. Kawaguchi, and S. T. Liu. (2007) A comprehensive library of mutations of Epstein Barr virus. J. Gen. Virol. 88: 2463-2472.
J. Garibal, E. Hollville, A. I. Bell, G. L. Kelly, B. Renouf, Y. Kawaguchi, A. B. Rickinson, and J. Wiels. (2007) Truncated form of the Epstein-Barr virus protein EBNA-LP protects against caspase-dependent apoptosis by inhibiting protein phosphatase 2A. J. Virol. 81: 7598-7607.
2006
A. Kato, M. Yamamoto, T. Ohno, M. Tanaka, T. Sata, Y. Nishiyama, and Y. Kawaguchi. (2006) Herpes Simplex Virus 1-Encoded Protein Kinase UL13 Phosphorylates the Viral Us3 Protein Kinase and Regulates nuclear Localization of Viral Envelopment Factors UL34 and UL31. J. Virol. 80: 1476-1486.
R. Asai, A. Kato, K. Kato, M. Kanamori-Koyama, K. Sugimoto, T. Sairenji, Y. Nishiyama, and Y. Kawaguchi. (2006) Epstein-Barr Virus Protein Kinase BGLF4 Is a Virion Tegument Protein That Dissociate From Virions in a Phosphorylation Dependent Process and Phosphorylates the Viral Imediate-Early Protein BZLF1. J. Virol. 80: 5125-5134.
A. Kudoh, T. Daikoku, Y. Ishimi, Y. Kawaguchi, N. Shirata, S. Iwahori, H. Isomura, and T. Tsurumi. (2006) Phosphorylation of MCM4 at Sites Inactivating DNA Helicase Activity of the MCM4-6-7 Complex during Epstein-Barr Virus Productive Replication. J.Virol. 80: 10064-10072.
J. Arii, O. Hushur, K. Kato, Y. Kawaguchi, Y. Tohya and H. Akashi. Construction of an infectious clone of canine herpesvirus genome as a bacterial artificial chromosome. (2006) Microbes and Infection 8: 1054-1063.
2005
A. Kato, M. Yamamoto, T. Ohno, H. Kodaira, Y. Nishiyama, and Y. Kawaguchi. (2005) Identification of proteins phosphorylated directly by the Us3 protein kinase encoded by herpes simplex virus 1. J. Virol. 79: 9325-9331.
M. Tanaka, Y. Nishiyama, T. Sata, and Y. Kawaguchi. (2005) The role of protein kinase activity expressed by the UL13 gene of herpes simplex virus 1: The activity is not essential for optimal expression of ICP0 and UL41.Virology 341: 301-312.
N. Nozawa, Y. Kawaguchi, M. Tanaka, A. Kato, A. Kato, H. Kimura, and Y. Nishiyama. (2005) Herpes Simplex Virus Type 1 UL51 Protein Is Involved in Maturation and Egress of Virus Particles. J. Virol. 79: 6947-6956.
T. Koshizuka, Y. Kawaguchi, and Y. Nishiyama. (2005) The HSV-2 membrane protein UL56 associates with the kinesin motor protein KIF1A. J. Gen. Virol. 86: 527-533.
A. Matsuzaki, Y. Yamauchi, A. Kato, F. Goshima, Y. Kawaguchi, T. Yoshikawa, and Y. Nishiyama. (2005) The Us3 protein kinase of herpes simplex virus type 2 is required for the stability of the UL46-encoded tegument protein and its association with virus particles. J. Gen. Virol. 86: 1979-1985.
F. Shaku, G. Matsuda, R. Furuya, C. Kamagata, M. Igarashi, M. Tanaka, M. Kanamori, Y. Nishiyama, N. Yamamoto, and Y. Kawaguchi (2005) Development of a Monoclonal Antibody against Epstein-Barr Virus Nuclear Antigen Leader Protein (EBNA-LP) that Can Detect EBNA-LP Expressed in P3HR1 Cells. Microbiol. Immunol. 49: 477-483.
2004
M. Kanamori, S. Watanabe, R. Honma, M. Kuroda, S. Imai, K. Takada, N. Yamamoto, Y. Nishiyama, and Y. Kawaguchi. (2004) Epstein-Barr Virus Nuclear Antigen Leader Protein Induces Expression of Thymus and Activation-Regulated Chemokine in B Cells. J. Virol. 78: 3984-3993.
M. Tanaka, H. Kodaira, Y. Nishiyama, T. Sata and Y. Kawaguchi. (2004) Construction of recombinant herpes simplex virus type 1 expressing green fluorescence protein without loss of any viral genes. Microbes and Infection 6: 485-493.
L. Liang, M. Tanaka, Y. Kawaguchi, and J. D. Baines. (2004) Cell lines that support replication of a novel herpes simplex 1 UL31 deletion mutant can properly target UL34 protein to the nuclear rim in the absence of UL31. Virology 329: 68-76.
N. Nozawa, Y. Yamauchi, K. Ohtsuka, Y. Kawaguchi and Y. Nishiyama. (2004) Formation of aggresome-like structures in herpes simplex virus type 2-infected cells and a potential role in virus assembly. Exp. Cell Res.299: 486-497.
2003
Y. Kawaguchi, K. Kato, M. Tanaka, M. Kanamori, Y. Nishiyama, and Y. Yamanashi. (2003) Conserved Protein Kinases Encoded by Herpesviruses and a Cellular Protein Kinase Cdc2 Target the Same Phosphorylation Site In Eukaryotic Elongation Factor 1d. J. Virol. 77: 2359-2368.
M. Tanaka, H. Kagawa, Y. Yamanashi, T. Sata and Y. Kawaguchi.(2003) Construction of an Excisable Bacterial Artificial Chromosome Containing a Full-Length Infectious Clone of Herpes Simplex Virus Type 1: Viruses Reconstituted from the Clone Exhibits Wild-Type Properties In Vitro and In Vivo. J. Virol. 77: 1382-1391.
Y. Kawaguchi and K. Kato. (2003) Protein kinases conserved in herpesviruses potentially share a function mimicking the cellular protein kinase cdc2. Rev. Med. Virol. 13: 331-340.
K. Kato, A. Yokoyama, Y. Tohya, H. Akashi, Y. Nishiyama, and Y. Kawaguchi. (2003) Identification of protein kinases responsible for phosphorylation of Epstein-Barr virus nuclear antigen leader protein at serine 35 that regulates its coactivator function. J. Gen. Virol. 84: 3381-3392.
M. Igarashi, Y. Kawaguchi*, K. Hirai, and F. Mizuno. (2003) Physical interaction of Epstein-Barr Virus (EBV) nuclear antigen leader protein (EBNA-LP) with human estrogen-related receptor 1 (hERR1): hERR1 interacts with a conserved domain of EBNA-LP that is critical for EBV-induced B-cell immortalization. J. Gen. Virol. 84: 319-327. *Corresponding author
G. Matsuda, K. Nakajima, Y. Kawaguchi*, Y. Yamanashi and K. Hirai. (2003) Epstein-Barr virus (EBV) nuclear antigen leader protein (EBNA-LP) forms complexes with a cellular anti-apoptosis protein bcl-2 or its EBV counterpart BHRF1 through HS1-associated protein X-1. Microbiol. Immunol. 47: 91-99. *Corresponding author
2002
M. Tanaka, A. Yokoyama, M. Igarashi, G. Matsuda, K. Kato, M. Kanamori, H. Yamada, K. Hirai, Y. Kawaguchi* and Yuji Yamanashi. (2002) The Conserved region CR2 of Epstein-Barr Virus Nuclear Antigen Leader Protein Is a Multifunctional Domain that mediates Self-Association As Well As Nuclear Localization and Nuclear Matrix Association. J. Virol. 76: 1025-1032. *Corresponding author
K. Kato, Y. Izumiya, Y. Tohya, E. Takahashi, K. Hirai, and Y. Kawaguchi. (2002) Characterization of the regulatory function of the Marek’s disease virus serotype 1 ICP22 homologue. Vet. Microbiol. 85: 305-313.
R. Katsu, H. Onogi, K. Wada, Y. Kawaguchi, and M. Hagiwara. (2002) Novel SR-rich-related protein Clasp specifically interacts with inactivated Clk4 and induces the exon inclusion of Clk. J. Biol. Chem. 277: 44220-44228.
2001
Y. Kawaguchi, M. Tanaka, A. Yokoyama, G. Matsuda, K. Kato, H. Kagawa, K. Hirai, and B. Roizman. (2001) Herpes Simplex Virus Type 1 a Regulatory Protein ICP0 Functionally Interacts with a Cellular Transcription Factor BMAL1. Proc. Natl. Acad. Sci. USA 98: 1877-1882 .
Yokoyama, M. Tanaka, G. Matsuda, K. Kato, M. Kanamori, H. Kawasaki, H. Hirano, I. Kitabayashi, M. Ohki, K. Hirai, and Y. Kawaguchi. (2001) Identification of major phosphorylation sites of Epstein-Barr virus nuclear antigen leader protein (EBNA-LP): The function of EBNA-LP to induce latent membrane protein 1 co-operatively with EBNA-2 is regulated by phosphorylation. J. Virol. 75: 5119-5128.
Yokoyama, Y. Kawaguchi*, I. Kitabayashi, M. Ohki, and K. Hirai. (2001) The Conserved Domain CR2 of Epstein-Barr Virus Nuclear Antigen Leader Protein is Responsible Not Only for Nuclear Matrix Association But Also for Nuclear Localization. Virology 279: 401-413. *Corresponding author
K. Kato, Y. Kawaguchi*, M. Tanaka, Mie Igarashi, Akihiko Yokoyama, Go Matsuda, Mikiko Kanamori, Kaori Nakajima, Yorihiro Nishimura, Masayuki Shimojima, Hang T. T. Phung, Eiji Takahashi, and Kanji Hirai. (2001) Epstein-Barr Virus Encoded-Protein Kinase BGLF Mediates Hyper-phosphorylation of Cellular Elongation Factor1d (EF-1d): EF-1d Is Universally Modified by Conserved Protein Kinases of Herpesviruses. J. Gen. Virol. 82: 1457-1463. *Corresponding author
2000
Y. Kawaguchi, K. Nakajima, M. Igarashi, T. Morita, M. Tanaka, M. Suzuki, A. Yokoyama, G. Matsuda, K. Kato, M. Kanamori, and K. Hirai. (2000) Interaction of Epstein-Barr Virus Nulear Antigen Leader Protein (EBNA-LP) with HS1-associated protein X-1: Implication of cytoplasmic function of EBNA-LP. J. Virol. 74: 10104-10111.
K. Sonoda, M. Sakaguchi, H. Okamura, K. Yokogawa, E. Tokunaga, S. Tokiyoshi, Y. Kawaguchi, and K. Hirai. (2000). Development of effective polyvalent vaccine against both Marek's and Newcastle diseases based on recombinant Marek's disease virus type 1 in commercial chickens with maternal antibodies. J. Virol. 74: 3217-3226.
1999年以前
Y. Kawaguchi, T. Matsumuta, B. Roizman, and K. Hirai. (1999) The cellular elongation factor 1d is modified in cells infected with representative alpha-, beta, or gamma herpesviruses. J. Virol. 73: 4456-4460.
C. Van Sant, Y. Kawaguchi, and B. Roizman. (1999) A single amino acid substitution in the cyclin D binding domain of the infected cell protein No.0 abrogates the neuroinvasiveness of herpes simplex virus without affecting its ability to replicate. Proc. Natl. Acad. Sci. USA 96: 8184-8189.
Y. Kawaguchi, C. Van Sant, and B. Roizman. Eukaryotic elongation factor 1d is hyperphosphorylated by the protein kinase encoded by the UL13 gene of herpes simplex virus 1. (1998) J. Virol. 72: 1731-1736.
Y. Ikeda, Y. Inoshima, Y. Kawaguchi, K. Maeda, M. Kohmoto, T. Miyazawa, C. Kai, and T. Mikami. (1998) Protein-binding properties of the putative AP-1 and ATF sequence in the feline immunodeficiency virus long terminal repeat. J. Gen. Virol. 78: 95-99.
Y. Kawaguchi, R. Bruni, and B. Roizman. (1997) Interaction of herpes simplex virus 1 a regulatory protein ICP0 with elogation factor 1d: ICP0 affects translational machinery. J. Virol. 71: 1019-1024.
Y. Kawaguchi, C. Van Sant, and B. Roizman. (1997) Herpes simplex virus-1 a regulatory protein ICP0 interacts with and stabilizes cell cycle regulator cyclin D3. J. Virol. 71: 7328-7336.
K. Hirasawa, H. S. Jun, K. Maeda, Y. Kawaguchi, S. Itagaki, T. Mikami, H. S. Baek, K. Doi, and J. W. Yoon. (1997) Possible role of macrophage-derived soluble mediators in the pathogenesis of encephalomyocarditis virus-induced diabetes in mice. J. Virol. 71: 4024-4031.
Y. Tohya, N. Yokoyama, K. Maeda, Y. Kawaguchi and T. Mikami. (1997) Mapping of antigenic sites involved in neutralization on the capsid protein of feline calicivirus. J. Gen. Virol. 78: 303-305.
Y. Kawaguchi, K. Maeda, N. Yokoyama, K. Fujita, M. Ono, Y. Tohya, and T. Mikami. (1997) Expression of feline herpesvirus type 1 ICP4 gene is controlled by two alternative promoters. Arch Virol. 142: 239-253.
Y. Inoshima, M. Kohmoto, Y. Ikeda, H. Yamada, Y. Kawaguchi, K. Tomonaga, T. Miyazawa, T. Umemura, C. Kai and T. Mikami. (1996) Roles of the auxiliary genes and AP-1 binding sites in the long terminal repeat of feline immunodeficiency virus in early stage of infection in cats. J. Virol. 70: 8518-8526.
Y. Ikeda, K. Tomonaga, Y. Kawaguchi, M. Kohmoto, Y. Inoshima, Y. Tohya, C. Kai, T. Miyazawa, and T. Mikami. (1996) Cell-free feline immunodeficiency virus can infect a human cell line (MOLT-4 cells) but is a state of an absolute latency in the cells. J. Gen. Virol. 77: 1623-1630.
M. R. Pecoraro, K. Tomonaga, T. Miyazawa, Y. Kawaguchi, S. Sugita, Y. Tohya, C. Kai, M. E. Etcheverrigaray, and T. Mikami. (1996) Genetic diversity of Argentine isolates of feline immunodeficiency virus. J. Gen. Virol. 77: 2031-2035.
M. R. Pecoraro, Y. Kawaguchi, K. Maeda, Y. Inoshima, C. Kai, and T. Mikami. (1996) Molocular cloning of the feline CD8b chain. Immunology 89: 84-88.
N. Yokoyama, K. Maeda, Y. Tohya, 47. Y. Kawaguchi, K. Fujita, and T. Mikami. (1996) Recombinant feline herpesvirus type 1 expressing immunogenic proteins inducible vieus neutralizing antibody against feline calicivirus in cats. Vaccine. 14: 1657-1663.
Y. Kawaguchi, K. Maeda, M. Ono, N. Yokoyama, K. Fujita, Y. Tohya, C. Kai, and T. Mikami. (1996) Characterization of the feline herpesvirus type 1 immediate-early gene expression. J. Vet. Med. Sci. 58: 715-721.
Y. Kawaguchi, K. Tomonaga, K. Maeda, M. Ono, T. Miyazawa, M. Kohmoto, Y. Tohya, and T. Mikami. (1995) The C/EBP site in the feline immunodeficiency virus (FIV) long terminal repeat (LTR) is necessary for its efficient replication and is also involved in the inhibition of FIV LTR-directed gene expression by pseudorabies virus ICP4.Virology 208: 492-499.
K. Maeda, Y. Kawaguchi, M. Ono, T. Tajima and T. Mikami. (1995) Restriction endonuclease analysis of field isolates of feline herpes virus type 1 and identification of the heterogenous regions. J. Clin. Microbiol. 33: 217-221.
Y. Kawaguchi, K. Maeda, M. R. Pecoraro, Y. Inoshima, H.-K. Jang, M. Kohmoto, K. Iwatsuki, Y. Ikeda, M. Shimojima, Y. Tohya, C. Kai and T. Mikami. (1995) Feline herpesvirus type 1 ICP4 down-regulate feline immunodeficiency virus long terminal repeat (LTR)-directed gene expression via the C/EBP site in the LTR. J. Vet. Med. Sci. 57: 1129-1131.
Y. Kawaguchiand T. Mikami. (1995) Molecular interactions between retrocviruses and herpesviruses. J. Vet. Med. Sci. 57: 801-811.
Y. Kawaguchi, K. Maeda, T. Miyazawa, M. Ono, C. Kai, and T. Mikami. (1994) Nucleotide sequence and characterization of the feline herpesvirus type 1 immediate early gene. Virology 204: 430-435.
Y. Kawaguchi, K. Maeda, T. Miyazawa, M. Ono, K. Tsubota, K. Tomonaga, and T. Mikami (1994) Inhibition of feline immunodeficiency virus gene expression and replication by alphaherpesvirus ICP4 homologues. J. Gen. Virol.75: 2783-2787.
M. R. Pecoraro, Y. Kawaguchi, T. Miyazawa, J. Norimine, K. Maeda, T. Toyosaki, Y. Tohya, C. Kai, and T. Mikami. (1994) Isolation, sequence and expression of a cDNA encoding the a-chain of the feline CD8. Immunology 81: 127-131.
M. Ono, Y. Kawaguchi, K. Maeda, N. Kamiya, Y. Tohya, C. Kai, and T. Mikami. (1994) Nucleotide sequence analysis of Marek's didease virus (MDV) serotype 2 homolog of MDV serotype 1 pp38, an antigen associated with transformed cells. Virology 201: 142-146.
K. Maeda, Y. Kawaguchi, M. Ono, Y. Inoshima, T. Miyazawa, Y. Tohya, C. Kai, and T. Mikami. (1994) A gD homologous gene of feline herpesvirus type 1 encodes a hemagglutinin (gp60). Virology 202: 1034-1038.
M. Kohmoto, T. Miyazawa, K. Tomonaga, Y. Kawaguchi, T. Mori, Y. Tohya, C. Kai, and T. Mikami (1994) Comparison of biological properties of feline immunodeficiency virus isolates using recombinant chimera viruses. J. Gen. Virol. 75: 1935-1942.
Y. Kawaguchi, Y. Tohya, T. Horimoto, K. Maeda, T. Miyazawa, and T. Mikami. (1994) Carrier-state infection of feline T-lymphoblastoid cells with feline calicivirus. Vet. Micobiol. 40: 379-386.
T. Miyazawa, M. Kohmoto, Y. Kawaguchi, K. Tomonaga, T. Toyosaki, K. Ikuta, A. Adachi, and T. Mikami. (1993) The AP-1 binding iste in the feline immunodeficiency virus long terminal repeat is not required for virus replication in feline T lymphocytes. J. Gen. Virol. 74: 1573-1580.
Y. Kawaguchi, J. Norimine, T. Miyazawa, C. Kai, and T. Mikami. (1992) Sequences within the feline immunodeficiency virus long terminal repeat that regulate gene expression and respond to activation by feline herpesvirus type 1. Virology 190: 465-468.
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