Journal Club
@ Dept. of Cell Signaling & Molecular Medicine
July 13, 2010
Interplay between Cdh1 and JNK activity during the cell cycle.
Gustavo J. et al
Nature Cell Biology, 12: 686-695 (2010) [Abstract]
June 29, 2010
ERK2 but not ERK1 induces epithelial-to-mesenchymal transformation via DEF motif-dependent signaling events.
Shin S. et al
Molecular Cell, 38: 114-127 (2010) [Abstract]
June 15, 2010
NLRC5 negatively regulates the NF-kB and type I interferon signaling pathways.
Cui J. et al
Cell, 141: 483-496 (2010) [Abstract]
June 1, 2010
Kinase-dead Braf and oncogenic Ras cooperate to drive tumor progression through Craf.
Heidorn SJ. et al
Cell, 140: 209-221 (2010) [Abstract]
Sep 14, 2010
Characterization of a domain that transiently converts class 2 DYRKs into intramolecular tyrosine kinases.
Kinstrie. et al
Science Signaling, 3, ra16:1-8 (2010) [Abstract]
Sep 28, 2010
Peroxisomes are signaling platforms for antiviral innate immunity.
Dixit. et al
Cell, 141: 668-681 (2010) [Abstract]
Oct 12, 2010
Control of endothelial sprouting by a Tel-CtBP complex.
Roukens MG. et al
Nature Cell Biology, 12: 933-942 (2010) [Abstract]
Oct 26, 2010
Asterless is a scaffold for the onset of centriole assembly.
Dzhindzhev NS. et al
Nature, 467: 714-718 (2010) [Abstract]
Nov 9, 2010
SUMOylation of the GTPase Rac1 is required for optimal cell migration.
Castillo-Lluva S. et al
Nature Cell Biology, 12: 1078-1085 (2010) [Abstract]
Nov 30, 2010
Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity.
Zhen W. et al
Cell, 141: 315-330 (2010) [Abstract]
Dec 21, 2010
A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration.
Smolen GA. et al
Genes & Development, 24: 2654-2665 (2010) [Abstract]
Jan 25, 2011
PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle.
Chang J. et al
EMBO J, 29: 2395-2406 (2010) [Abstract]
Feb 22, 2011
Activation of IFN-β expression by a viral mRNA through RNase L and MDA5.
Luthra et al
PNAS, 108: 2118-2123 (2011) [Abstract]
Mar 22, 2011
O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1.
Capotosti F. et al
Cell, 144: 376-388 (2011) [Abstract]
Apr 12, 2011
Retinoic acid-induced gene-1 (RIG-1) associates with the actin cytoskeleton via caspase activation and recruitment domain-dependent interactions.
Mukherjee A. et al
J. Biol. Chem., 284: 6486-6494 (2011) [Abstract]
Apr 26, 2011
Structural basis of the 9-fold symmetry of centrioles.
Kitagawa D. et al
Cell, 144: 364-375 (2011)
Structures of SAS-6 suggest its organization in centrioles.
van Breugel M. et al
Science, 331: 1196-1199 (2011)
May 17, 2011
ERK and PDE4 cooperate to induce RAF isoform switching in melanoma. Marquette A. et al
Nature Struct. Mol. Biol., 18: 584-591 (2011)
June 17, 2011
A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly.
Ohn T. et al
Nature Cell Biol., 10: 1224-1231 (2008)
June 21, 2011
Centriolar kinesin Kif24 interacts with CP110 to remodel microtubles and regulate ciliogenesis.
Kobayashi T. et al
Cell, 145: 914-925 (2011)
July 12, 2011
Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation.
Hsu JM. et al
Nature Cell Biol., 13: 174-181 (2011)
July 26, 2011
Klotho suppresses RIG-I-mediated senescence-associated inflammation.
Liu F. et al
Nature Cell Biol., 13: 254-262 (2011)
Sep 6, 2011
The ATAC acetyltransferase complex coordinates MAP kinases to regulate JNK target genes.
Suganuma T. et al
Cell, 142: 726-736 (2010)
Sep 20, 2011
The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSA-6 to control centrosome duplication.
Puklowski A. et al
Nature Cell Biol., 13: 1004-1009 (2011)
Oct 11, 2011
p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasis.
Lee J. et al
Nature Medicine, 17: 1251-1260 (2011)
Oct 25, 2011
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response.
Hou F. et al
Cell, 146: 448-461 (2011)
Nov 8, 2011
Metalloprotease type III effectors that specifically cleave JNK and NF-kB.
Baruch et al.
EMBO J, 30: 221-231 (2011)
Dec 6, 2011
Chromosome segregation errors as a cause of DNA damage and structural chromosome Janssen et al.
Science, 333: 1895-1898 (2011)
Dec 20, 2011
Conformational-sensing antibodies stabilize the oxidized form of PTP1B and inhibits its phosphatase activity.
Haque et al.
Cell, 147: 185-198 (2011)
Jan 10, 2012
PCBP2 mediates degradation of the adaptor MAVS via the HCT ubiquitin ligase AIP4.
You et al.
Nature Immunology, 10: 1300-1308 (2009)
Jan 30, 2012
JNK1 phosphorylation of Cdt1 inhibits recruitment of HBO1 histone acetylase and blocks replication licensing in response to stress.
Miotto B. et al.
Molecular Cell, 44: 62-71 (2011)
Feb 28, 2012
O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release.
Pathak S. et al.
EMBO J, 31: 1394-1404 (2012)
Apr 10, 2012
Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis.
Tarrant MK. et al.
Nature Chem Biol, 8: 262-269 (2012)
