【斎藤 泉　文献リスト】

【2015〜】
1.
Suzuki M., Kondo S., Pei Z., Maekawa A., Saito I. and Kanegae Y.
Preferable sites and orientations of transgene inserted in the adenovirus vector genome: the E3 site may be unfavorable for transgene position
Gene Ther., 22:421-429, 2015


【2010〜2014】
1.
Kondo S., Yoshida K., Suzuki M., Saito I., and Kanegae Y.
Adenovirus-encoding virus-associated RNAs suppress HDGF gene expression to support efficient viral replication
Plos One., 9: e108627, 2014

2.
Lystad AH, Ichimura Y, Takagi K, Yang Y, Pankiv S, Kanegae Y, Kageyama S, Suzuki M, Saito I, Mizushima T, Komatsu M, Simonsen A.
Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures.
EMBO Rep.,15:557-565, 2014

3.
Pei Z, Shi G, Kondo S, Ito M, Maekawa A, Suzuki M, Saito I, Suzuki T and Kanegae Y.
Adenovius vectors lacking virus-associated RNA expression enhance shRNA atctivity to suppress hepatitis C virus replication., Scientific Rep., 3:3575, 2013

4.
Maekawa A., Pei Z., Suzuki M., Fukuda F., Kondo S., Saito I., and Kanegae Y.
Efficient production of adenovirus vector lacking genes of virus-associated RNAs that disturb cellular RNAi machinery., Scientific Rep., 3: 1136, 2013.

5.
Kanegae Y., Ishimura M., Kondo S., and Saito I.
Influence of loxP insertion upstream of the cis-acting packaging domain on adenovirus packaging efficiency., Microbiol. Immunol., 56: 447-455, 2012

6.
Suzuki R, Saito K, Kato T, Shirakura M, Akazawa D, Ishii K, Aizaki H, Kanegae Y, Matsuura Y, Saito I, Wakita T, Suzuki T.
Trans-complemented hepatitis C virus particles as a versatile tool for study of virus assembly and infection. Virology., 432:29-38, 2012

7.
Pei Z., Kondo S., Kanegae Y., and Saito I.
Copy number of adenoviral vector genome transduced into target cells can be measured using quantitative PCR: Application to vector titration., Biochem. Biophys. Res. Communi., 417: 945-950, 2012.

8.
Takata Y., Kondo S. (equal contribution), Goda N., Kanegae Y., and Saito I.
Comparison of efficiency between FLPe and Cre for recombinase-mediated cassette exchange in vitro and in adenovirus vector production., Genes to Cells, 16: 765-777, 2011.

9.
Chiyo T, Sekiguchi S, Hayashi M, Tobita Y, Kanegae Y, Saito I, Kohara M.
Conditional gene expression in hepatitis C virus transgenic mice without induction of severe liver injury using a non-inflammatory Cre-expressing adenovirus. Virus Res., 160: 89-97, 2011.

10.
Ishijima N, Suzuki M, Ashida H, Ichikawa Y, Kanegae Y, Saito I, Borén T, Haas R, Sasakawa C, Mimuro H.
BabA-mediated adherence is a potentiator of the Helicobacter pylori type IV secretion system activity. J Biol Chem., 286: 25256-25264, 2011.

11.
Sakamoto S, Yazawa T, Baba Y, Sato H, Kanegae Y, Hirai T, Saito I, Goto T, Kurahashi K.
Keratinocyte growth factor gene transduction ameliorates pulmonary fibrosis induced by bleomycin in mice. Am J Respir Cell Mol Biol., 45: 489-497, 2011.

12.
Kanegae Y., Terashima M., Kondo S., Fukuda H., Maekawa A., Pei Z., and Saito I.
High-level expression by tissue/cancer-specific promoter with strict specificity using a single-adenoviral vector., Nucleic Acids Res., 39: e7, 2010.



【2005〜2009】
1.
Fukamachi K, Tanaka H, Hagiwara Y, Ohara H, Joh T, Iigo M, Alexander,D. B, Xu J, Long N, Takigahira M, Yanagihara K, Hino O, Saito I and Tsuda H.
An animal model of preclinical diagnosis of pancreatic ductal adenocarcinomas.　Biochem. Biophys. Res. Commun., 390: 636-641, 2009

2.
Kondo S, Tanaka Y, Nakano M, Saito I, & Kanegae Y.
Activities of various FLP recombinases expressed by adenovirus vectors in mammalian cells., J. Mol. Biol. 390: 221-230, 2009.

3.
Shibata H, Takano H, Ito M, Shioya H, Hirota M , Matsumoto H , Kakudo Y, Ishioka C, Akiyama T, Kanegae Y, Saito I, Noda T.
α-Catenin is essential in intestinal adenoma formation. Proc Natl Acad Sci U S A, 104: 18199-204, 2007.

4.
Nakai M, Komiya K, Murata M, Kimura T, Kanaoka M, Kanegae Y, and Saito I.
Expression of pIX Gene Induced by Transgene Promoter: Possible Cause of Host Immune Response in First-Generation Adenoviral Vectors. Hum Gene Ther. 18: 925-36, 2007.

5.
Baba Y, Yazawa T, Kanegae Y, Sakamoto S, Saito I, Morimura N, Goto T, Yamada Y, Kurahashi K.
Keratinocyte growth factor transduction ameliorates acute lung injury and mortality in mice. Hum Gene Ther. 18: 130-141, 2007.

6.
Ueda S, Fukamachi K, Matsuoka Y, Takasuka N, Takeshita F, Naito A, Iigo M, Alexander DB, Moore MA, Saito I, Ochiya T, Tsuda H.
Ductal origin of pancreatic adenocarcinomas induced by conditional activation of a human Ha-ras oncogene in rat pancreas. Carcinogenesis. 27: 2497-2510, 2006.

7.
Cheong J, Yamada Y, Yamashita R, Irie T, Kanai A, Wakaguri H, Nakai K, Ito T, Saito I, Sugano S, Suzuki Y.
Diverse DNA methylation statuses at alternative promoters of human genes in various tissues. DNA Research. 13: 155-167, 2006.

8.
Kondo S, Takahashi Y, Shiozawa S, Ichise H, Yoshida N, Kanegae Y, and Saito I.
Efficient sequential gene regulation via FLP - and Cre - recombinase using adenovirus vector in mammalian cells including mouse ES cells. Microbiol Immunol. 50: 831-843, 2006.

9.
Fukuda H, Terashima M, Koshikawa M, Kanegae Y, and Saito I.
Possible mechanism of adenovirus generation from a viral genome tagged with nucleotides at its ends. Microbiol Immunol. 50: 643-654, 2006.

10.
Baba Y, Nakano M, Yamada Y, Saito I, and Kanegae Y.
Practical range of effective dose for Cre recombinase-expressing recombinant adenovirus without cell toxicity in mammalian cells. Microbiol Immunol, 49: 559-570, 2005.

11.
Kido T, Arata S, Suzuki R, Hosono T, Nakanishi Y, Miyazaki J, Saito I, Kuroki T, and Shioda S.
The testicular fatty acid binding protein PERF15 regulates the fate of germ cells in PERF15 transgenic mice. Dev Growth Differ, 47: 15-24, 2005.

12.
Miyamoto T, Kaneko T, Yamashita M, Tenda Y, Inami M, Suzuki A, Ishii S, Kimura M, Hashimoto K, Shimada H, Yahata H, Ochiai T, Saito I, DeGregori J, and Nakayama T.
Prolonged skin allograft survival by IL-10 gene-introduced CD4 T cell administration. Int Immunol, 17: 759-768, 2005.

13.
Nakano M, Odaka K, Takahashi Y, Ishimura M, Saito I, and Kanegae Y.
Production of viral vectors using recombinase-mediated cassette exchange. Nucleic Acids Res, 33: e76, 2005.

14.
Ugai H, Murata T, Nagamura Y, Ugawa Y, Suzuki E, Nakata H, Kujime Y, Inamoto S, Hirose M, Inabe K, Terashima M, Yamasaki T, Liu B, Nakade K, Pan J, Kimura M, Saito I, Hamada H, Obata Y, and Yokoyama K. K.
A database of recombinant viruses and recombinant viral vectors available from the RIKEN DNA bank. J Gene Med, 7: 1148-1157, 2005.


【2000〜2004】
1.
Kondo S, Okuda A, Sato H, Tachikawa N, Terashima M, Kanegae Y, and Saito I.
Simultaneous on/off regulation of transgenes located on a mammalian chromosome with Cre-expressing adenovirus and a mutant loxP. Nucleic Acids Res, 31: e76, 2003.

2.
Horie R, Watanabe T, Morishita Y, Ito K, Ishida T, Kanegae Y, Saito I, Higashihara M, Mori S, and Kadin M. E.
Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin-Reed-Sternberg cells. Oncogene, 21: 2493-2503, 2002.

3.
Kim J. M, Nakao K, Nakamura K, Saito I, Katsuki M, Arai K, and Masai H.
Inactivation of Cdc7 kinase in mouse ES cells results in S-phase arrest and p53-dependent cell death. Embo J, 21: 2168-2179, 2002.

4.
Yamamoto H, Ochiya T, Takeshita F, Toriyama-Baba H, Hirai K, Sasaki H, Sakamoto H, Yoshida T, Saito I, and Terada M.
Enhanced skin carcinogenesis in cyclin D1-conditional transgenic mice: cyclin D1 alters keratinocyte response to calcium-induced terminal differentiation. Cancer Res, 62: 1641-1647, 2002.

5.
Yamamoto H, Ochiya T, Tamamushi S, Toriyama-Baba H, Takahama Y, Hirai K, Sasaki H, Sakamoto H, Saito I, Iwamoto T, Kakizoe T, and Terada M.
HST-1/FGF-4 gene activation induces spermatogenesis and prevents adriamycin-induced testicular toxicity. Oncogene, 21: 899-908, 2002.

6.
Haruta M, Kosaka M, Kanegae Y, Saito I, Inoue T, Kageyama R, Nishida A, Honda Y, and Takahashi M.
Induction of photoreceptor-specific phenotypes in adult mammalian iris tissue. Nat Neurosci, 4: 1163-1164, 2001.

7.
Hirano T, Kaneko S, Kaneda Y, Saito I, Tamaoki T, Furuyama J, Kobayashi K, Ueki T, and Fujimoto J.
HVJ-liposome-mediated transfection of HSVtk gene driven by AFP promoter inhibits hepatic tumor growth of hepatocellular carcinoma in SCID mice. Gene Ther, 8: 80-83, 2001.

8.
Iino M, Goto K, Kakegawa W, Okado H, Sudo M, Ishiuchi S, Miwa A, Takayasu Y, Saito I, Tsuzuki K, and Ozawa S.
Glia-synapse interaction through Ca2+-permeable AMPA receptors in Bergmann glia. Science, 292: 926-929, 2001.

9.
Ijima K, Murakami M, Okamoto H, Inobe M, Chikuma S, Saito I, Kanegae Y, Kawaguchi Y, Kitabatake A, and Uede T.
Successful gene therapy via intraarticular injection of adenovirus vector containing CTLA4IgG in a murine model of type II collagen- induced arthritis. Hum Gene Ther, 12: 1063-1077, 2001.

10.
Nakano M, Ishimur M, Chiba J, Kanegae Y, and Saito I.
DNA substrates influence the recombination efficiency mediated by FLP recombinase expressed in mammalian cells. Microbiol Immunol, 45: 657-665, 2001.

11.
Nakano M, Odaka K, Ishimura M, Kondo S, Tachikawa N, Chiba J, Kanegae Y, and Saito I.
Efficient gene activation in cultured mammalian cells mediated by FLP recombinase-expressing recombinant adenovirus. Nucleic Acids Res, 29: E40, 2001.

12.
Sakai Y, Kaneko S, Sato Y, Kanegae Y, Tamaoki T, Saito I, and Kobayashi K.
Gene therapy for hepatocellular carcinoma using two recombinant adenovirus vectors with alpha-fetoprotein promoter and Cre/lox P system. J Virol Methods, 92: 5-17., 2001.

13.
Takehara M, Murakami M, Inobe M, Tanaka K, Chikuma S, Saito I, Kanegae Y, Yasunami Y, Nakano M, Yamashita K, Todo S, and Uede T.
Long-term acceptance of allografts by in vivo gene transfer of regulatable adenovirus vector containing CTLA4IgG and loxP. Hum Gene Ther, 12: 415-426., 2001.

14.
Fujita-Kusano A, Naito Y, Saito I, and Kobayashi I. Mutation correction by homologous recombination with an adenovirus vector. Methods Mol Biol, 133: 101-109, 2000.

15.
Morimura T, Goitsuka R, Zhang Y, Saito I, Reth M, and Kitamura D.
Cell-cycle arrest and apoptosis induced by Notch1 in B cells. J Biol Chem, 2000.

16.
Takiguchi M, Murakami M, Nakagawa I, Saito I, Hashimoto A, and Uede T.
CTLA4IgG gene delivery prevents autoantibody production and lupus nephritis in MRL/lpr mice. Life Sci, 66: 991-1001, 2000.

17.
Wakita T, Katsume A, Kato J, Taya C, Yonekawa H, Kanegae Y, Saito I, Hayashi Y, Koike M, Miyamoto M, Hiasa Y, and Kohara M.
Possible role of cytotoxic T cells in acute liver injury in hepatitis C virus cDNA transgenic mice mediated by Cre/loxP system [In Process Citation]. J Med Virol, 62: 308-317, 2000.



【1995〜1999】
1.
Bilbao G, Zhang H, Contreras J. L, Zhou T, Feng M, Saito I, Mountz J. D, and Curiel D. T.
Construction of a recombinant adenovirus vector encoding Fas ligand with a CRE/Loxp inducible system. Transplant Proc, 31: 792-793, 1999.

2.
Chiba T, Kogishi K, Wang J, Xia C, Matsushita T, Miyazaki J, Saito I, Hosokawa M, and Higuchi K.
Mouse senile amyloid deposition is suppressed by adenovirus-mediated overexpression of amyloid-resistant apolipoprotein A-II. Am J Pathol, 155: 1319-1326, 1999.

3.
Ishii A, Hagiwara Y, Saito Y, Yamamoto K, Yuasa K, Sato Y, Arahata K, Shoji S, Nonaka I, Saito I, Nabeshima Y, and Takeda S.
Effective adenovirus-mediated gene expression in adult murine skeletal muscle. Muscle Nerve, 22: 592-599, 1999.

4.
Kobayashi M, Nagata S, Iwasaki T, Yanagihara K, Saito I, Karouji Y, Ihara S, and Fukui Y.
Dedifferentiation of adenocarcinomas by activation of phosphatidylinositol 3-kinase. Proc Natl Acad Sci U S A, 96: 4874-4879, 1999.

5.
Nagasaki Y, Matsubara Y, Takano H, Fujii K, Senoo M, Akanuma J, Takahashi K, Kure S, Hara M, Kanegae Y, Saito I, and Narisawa K.
Reversal of hypopigmentation in phenylketonuria mice by adenovirus-mediated gene transfer. Pediatr Res, 45: 465-473, 1999.

6.
Nakamura T, Akiyoshi H, Saito I, and Sato K.
Adenovirus-mediated gene expression in the septal cells of cirrhotic rat livers. J Hepatol, 30: 101-106, 1999.

7.
Ogasawara Y, Mizukami H, Urabe M, Kume A, Kanegae Y, Saito I, Monahan J, and Ozawa K.
Highly regulated expression of adeno-associated virus large Rep proteins in stable 293 cell lines using the Cre/loxP switching system. J Gen Virol, 80: 2477-2480, 1999.

8.
Shintani Y, Yotsuyanagi H, Moriya K, Fujie H, Tsutsumi T, Kanegae Y, Kimura S, Saito I, and Koike K.
Induction of apoptosis after switch-on of the hepatitis B virus X gene mediated by the Cre/loxP recombination system. J Gen Virol, 80: 3257-3265, 1999.

9.
Sudo M, Okado H, Iino M, Tsuzuki K, Miwa A, Kanegae Y, Saito I, and Ozawa S.
Postsynaptic expression of Ca2+-permeable AMPA-type glutamate receptor channels by viral-mediated gene transfer. Brain Res Mol Brain Res, 65: 176-185, 1999.

10.
Yamabe K, Shimizu S, Ito T, Yoshioka Y, Nomura M, Narita M, Saito I, Kanegae Y, and Matsuda H.
Cancer gene therapy using a pro-apoptotic gene, caspase-3. Gene Ther, 6: 1952-1959, 1999.

11.
Yamabe K, Shimizu S, Ito T, Yoshioka Y, Nomura M, Narita M, Saito I, Kanegae Y, and Matsuda H.
Cancer gene therapy using a pro-apoptotic gene, caspase-3. Gene Ther, 6: 1952-1959, 1999.

12.
Aoki Y, Aizaki H, Shimoike T, Tani H, Ishii K, Saito I, Matsuura Y, and Miyamura T.
A human liver cell line exhibits efficient translation of HCV RNAs produced by a recombinant adenovirus expressing T7 RNA polymerase. Virology, 250: 140-150, 1998.

13.
Arai T, Matsumoto K, Saitoh K, Ui M, Ito T, Murakami M, Kanegae Y, Saito I, Cosset F. L, Takeuchi Y, and Iba H. A new system for stringent, high-titer vesicular stomatitis virus G protein-pseudotyped retrovirus vector induction by introduction of Cre recombinase into stable prepackaging cell lines. J Virol, 72: 1115-1121, 1998.

14.
Hiasa Y, Horiike N, Akbar S. M, Saito I, Miyamura T, Matsuura Y, and Onji M.
Low stimulatory capacity of lymphoid dendritic cells expressing hepatitis C virus genes. Biochem Biophys Res Commun, 249: 90-95, 1998.

15.
Kano M, Igarashi H, Saito I, and Masuda M.
Cre-loxP-mediated DNA flip-flop in mammalian cells leading to alternate expression of retrovirally transduced genes. Biochem Biophys Res Commun, 248: 806-811, 1998.

16.
Lee G. and Saito I.
Role of nucleotide sequences of loxP spacer region in Cre-mediated recombination. Gene, 216: 55-65, 1998.

17.
Lu D, Tamemoto H, Shibata H, Saito I, and Takeuchi T.
Regulatable production of insulin from primary-cultured hepatocytes: insulin production is up-regulated by glucagon and cAMP and down-regulated by insulin. Gene Ther, 5: 888-895, 1998.

18.
Nakagawa I, Murakami M, Ijima K, Chikuma S, Saito I, Kanegae Y, Ishikura H, Yoshiki T, Okamoto H, Kitabatake A, and Uede T.
Persistent and secondary adenovirus-mediated hepatic gene expression using adenovirus vector containing CTLA4IgG [see comments]. Hum Gene Ther, 9: 1739-1745, 1998.

19.
Nishimura I, Uetsuki T, Dani S. U, Ohsawa Y, Saito I, Okamura H, Uchiyama Y, and Yoshikawa K.
Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus-mediated gene transfer. J Neurosci, 18: 2387-2398, 1998.

20.
Okuyama T, Fujino M, Li X. K, Funeshima N, Kosuga M, Saito I, Suzuki S, and Yamada M.
Efficient Fas-ligand gene expression in rodent liver after intravenous injection of a recombinant adenovirus by the use of a Cre-mediated switching system. Gene Ther, 5: 1047-1053, 1998.

21.
Sato Y, Tanaka K, Lee G, Kanegae Y, Sakai Y, Kaneko S, Nakabayashi H, Tamaoki T, and Saito I.
Enhanced and specific gene expression via tissue-specific production of Cre recombinase using adenovirus vector. Biochem Biophys Res Commun, 244: 455-462, 1998.

22.
Shinoura N, Ohashi M, Yoshida Y, Asai A, Kirino T, Saito I, and Hamada H.
Construction, propagation, and titer estimation of recombinant adenoviruses carrying proapoptotic genes. Hum Gene Ther, 9: 2683-2689, 1998.

23.
Tsubota K, Inoue H, Ando K, Ono M, Yoshino K, and Saito I.
Adenovirus-mediated gene transfer to the ocular surface epithelium. Exp Eye Res, 67: 531-538, 1998.

24.
Wakita T, Taya C, Katsume A, Kato J, Yonekawa H, Kanegae Y, Saito I, Hayashi Y, Koike M, and Kohara M.
Efficient conditional transgene expression in hepatitis C virus cDNA transgenic mice mediated by the Cre/loxP system. J Biol Chem, 273: 9001-9006, 1998.

25.
Yasuda H, Nagata M, Arisawa K, Yoshida R, Fujihira K, Okamoto N, Moriyama H, Miki M, Saito I, Hamada H, Yokono K, and Kasuga M.
Local expression of immunoregulatory IL-12p40 gene prolonged syngeneic islet graft survival in diabetic NOD mice. J Clin Invest, 102: 1807-1814, 1998.

26.
Zhang H. G, Bilbao G, Zhou, T, Contreras J. L, Gomez-Navarro J, Feng M, Saito I, Mountz J. D, and Curiel D. T.
Application of a Fas ligand encoding a recombinant adenovirus vector for prolongation of transgene expression. J Virol, 72: 2483-2490, 1998.

27.
Endo F, Kubo S, Awata H, Kiwaki K, Katoh H, Kanegae Y, Saito I, Miyazaki J, Yamamoto T, Jakobs C, Hattori S, and Matsuda I.
Complete rescue of lethal albino c14CoS mice by null mutation of 4-hydroxyphenylpyruvate dioxygenase and induction of apoptosis of hepatocytes in these mice by in vivo retrieval of the tyrosine catabolic pathway. J Biol Chem, 272: 24426-24432, 1997.

28.
Gojo S, Kitamura S, Hatano O, Takakusu A, Hashimoto K, Kanegae Y, and Saito I.
Transplantation of genetically marked cardiac muscle cells. J Thorac Cardiovasc Surg, 113: 10-18, 1997.

29.
Hayashi S, Koike C, Namii Y, Nagasaka T, Katayama A, Saito I, Okada H, Yokoyama I, Ohtsuka S, Uchida K, and Takagi H.
Adenovirus-mediated gene transfer to the xenogeneic liver in liver xenotransplantation: the transduction of complement regulatory factor genes (DAF and HRF20). Transplant Proc, 29: 2211, 1997.

30.
Hayashi S, Nagasaka T, Katayama A, Saito I, Hamada H, Kobayashi T, Yokoyama I, Ohtsuka S, Uchida K, and Takagi H.
Adenovirus-mediated gene transfer of antisense ribozyme for alpha (1,3)galactosyltransferase gene and alpha (1,2)fucosyltransferase gene in xenotransplantation. Transplant Proc, 29: 2213, 1997.

31.
Hayashi S, Namii Y, Kozima T, Kobayashi T, Yokoyama I, Saito I, Hamada H, Ohtsuka S, Uchida K, and Takagi H.
Effect of CTLA4-Ig gene transfer using adenoviral vector in organ and cell transplantation. Transplant Proc, 29: 2212, 1997.

32.
Heike Y, Takahashi M, Kanegae Y, Sato Y, Saito I, and Saijo N.
Interleukin-2 gene transduction into freshly isolated lung adenocarcinoma cells with adenoviral vectors. Hum Gene Ther, 8: 1-14, 1997.

33.
Kobayashi M, Nagata S, Kita Y, Nakatsu N, Ihara S, Kaibuchi K, Kuroda S, Ui M, Iba H, Konishi H, Kikkawa U, Saito I, and Fukui Y.
Expression of a constitutively active phosphatidylinositol 3-kinase induces process formation in rat PC12 cells. Use of Cre/loxP recombination system. J Biol Chem, 272: 16089-16092, 1997.

34.
Kubo S, Kiwaki K, Awata H, Katoh H, Kanegae Y, Saito I, Yamamoto T, Miyazaki J, Matsuda I, and Endo F.
In vivo correction with recombinant adenovirus of 4-hydroxyphenylpyruvic acid dioxygenase deficiencies in strain III mice. Hum Gene Ther, 8: 65-71, 1997.

35.
Shibata H, Toyama K, Shioya H, Ito M, Hirota M, Hasegawa S, Matsumoto H, Takano H, Akiyama T, Toyoshima K, Kanamaru R, Kanegae Y, Saito I, Nakamura Y, Shiba K, and Noda T.
Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. Science, 278: 120-123, 1997.

36.
Shoji I, Aizaki H, Tani H, Ishii K, Chiba T, Saito I, Miyamura T, and Matsuura Y.
Efficient gene transfer into various mammalian cells, including non-hepatic cells, by baculovirus vectors. J Gen Virol, 78: 2657-2664, 1997.

37.
Terashima T, Miwa A, Kanegae Y, Saito I, and Okado H.
Retrograde and anterograde labeling of cerebellar afferent projection by the injection of recombinant adenoviral vectors into the mouse cerebellar cortex. Anat Embryol (Berl), 196: 363-382, 1997.

38.
Hashimoto M, Aruga J, Hosoya Y, Kanegae Y, Saito I, and Mikoshiba K.
A neural cell-type-specific expression system using recombinant adenovirus vectors. Hum Gene Ther, 7: 149-158, 1996.

39.
Ishihara H, Nakazaki M, Kanegae Y, Inukai K, Asano T, Katagiri H, Yazaki Y, Kikuchi M, Miyazaki J, Saito I, and Oka Y.
Effect of mitochondrial and/or cytosolic glycerol 3-phosphate dehydrogenase overexpression on glucose-stimulated insulin secretion from MIN6 and HIT cells. Diabetes, 45: 1238-1244, 1996.

40.
Kanai F, Shiratori Y, Yoshida Y, Wakimoto H, Hamada H, Kanegae Y, Saito I, Nakabayashi H, Tamaoki T, Tanaka T, Lan K. H, Kato N, Shiina S, and Omata M.
Gene therapy for alpha-fetoprotein-producing human hepatoma cells by adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene. Hepatology, 23: 1359-1368, 1996.

41.
Kanegae Y, Takamori K, Sato Y, Lee G, Nakai M, and Saito I.
Efficient gene activation system on mammalian cell chromosomes using recombinant adenovirus producing Cre recombinase. Gene, 181: 207-212, 1996.

42.
Kiwaki K, Kanegae Y, Saito I, Komaki S, Nakamura K, Miyazaki J. I, Endo F, and Matsuda I.
Correction of ornithine transcarbamylase deficiency in adult spf(ash) mice and in OTC-deficient human hepatocytes with recombinant adenoviruses bearing the CAG promoter. Hum Gene Ther, 7: 821-830, 1996.

43.
Makimura M, Miyake S, Akino N, Takamori K, Matsuura Y, Miyamura T, and Saito I.
Induction of antibodies against structural proteins of hepatitis C virus in mice using recombinant adenovirus. Vaccine, 14: 28-36, 1996.

44.
Miyake S, Makimura M, Kanegae Y, Harada S, Sato Y, Takamori K, Tokuda C, and Saito I.
Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc Natl Acad Sci U S A, 93: 1320-1324, 1996.

45.
Miyake S, Saito I, Kobayashi H, and Yamashita S.
Identification of two Xenopus laevis genes, xMCM2 and xCDC46, with sequence homology to MCM genes involved in DNA replication. Gene, 175: 71-75, 1996.

46.
Ohashi T, Watabe K, Sato Y, Saito I, Barranger J. A, Matalon R, and Eto Y.
Gene therapy for metachromatic leukodystrophy. Acta Paediatr Jpn, 38: 193-201, 1996.

47.
Ozaki K, Yoshida T, Ide H, Saito I, Ikeda Y, Sugimura T, and Terada M.
Use of von Willebrand factor promoter to transduce suicidal gene to human endothelial cells, HUVEC. Hum Gene Ther, 7: 1483-1490, 1996.

48.
Sekiguchi H, Isobe K, Akiyama S, Yi H, Takeshita H, Watanabe T, Kasai Y, Ito K, Kanegae Y, Saito I, Nakashima I, and Takagi H.
Efficient adenovirus-mediated gene transfer into human cancer cell lines derived from digestive tract. Int. J. Oncol., 8: 283-287, 1996.

49.
Suzuki T, Matsuura Y, Harada T, Suzuki R, Saito I, and Miyamura T.
Molecular basis of subcellular localization of HCV core protein. Liver, 16: 221-224, 1996.79. Tsukui T, Kanegae Y, Saito I, and Toyoda Y. Transgenesis by adenovirus-mediated gene transfer into mouse zona-free eggs. Nat Biotechnol, 14: 982-985, 1996.

50.
Chang H, Katoh T, Noda M, Kanegae Y, Saito I, Asano S, and Kurokawa K.
Highly efficient adenovirus-mediated gene transfer into renal cells in culture. Kidney Int, 47: 322-326, 1995.

51.
Fujita, A., Sakagami, K., Kanegae, Y., Saito, I., and Kobayashi, I.
Gene targeting with a replication-defective adenovirus vector. J Virol, 69: 6180-6190, 1995.

52.
Harada, S., Suzuki, R., Ando, A., Watanabe, Y., Yagi, S., Miyamura, T., and Saito, I.
Establishment of a cell line constitutively expressing E2 glycoprotein of hepatitis C virus and humoral response of hepatitis C patients to the expressed protein. J Gen Virol, 76: 1223-1231, 1995.

53.
Harada, T., Kim, D. W., Sagawa, K., Suzuki, T., Takahashi, K., Saito, I., Matsuura, Y., and Miyamura, T.
Characterization of an established human hepatoma cell line constitutively expressing non-structural proteins of hepatitis C virus by transfection of viral cDNA. J Gen Virol, 76: 1215-1221, 1995.

54.
Kanegae, Y., Lee, G., Sato, Y., Tanaka, M., Nakai, M., Sakaki, T., Sugano, S., and Saito, I.
Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase. Nucleic Acids Res, 23: 3816-3821, 1995.

55.
Koike, K., Moriya, K., Ishibashi, K., Matsuura, Y., Suzuki, T., Saito, I., Iino, S., Kurokawa, K., and Miyamura, T.
Expression of hepatitis C virus envelope proteins in transgenic mice. J Gen Virol, 76: 3031-3038, 1995.

56.
Kojima, H., Inuzuka, S., Miwa, T., Furukawa, S., Hayashi, K., Kanegae, Y., Saito, I., Ohishi, N., Takamori, M., and Yagi, K.
Construction and characterization of adenoviral vector expressing biologically active brain-derived neurotrophic factor. Biochem Biophys Res Commun, 212: 712-717, 1995.

57.
Konishi, H., Ochiya, T., Sakamoto, H., Tsukamoto, M., Saito, I., Muto, T., Sugimura, T., and Terada, M.
Effective prevention of thrombocytopenia in mice using adenovirus-mediated transfer of HST-1 (FGF-4) gene [published erratum appears in J Clin Invest 1995 Nov;96(5):2543]. J Clin Invest, 96: 1125-1130, 1995.

58.
Li, J. J., Ueno, H., Pan, Y., Tomita, H., Yamamoto, H., Kanegae, Y., Saito, I., and Takeshita, A.
Percutaneous transluminal gene transfer into canine myocardium in vivo by replication-defective adenovirus. Cardiovasc Res, 30: 97-105, 1995.

59.
Li, J. J., Ueno, H., Tomita, H., Yamamoto, H., Kanegae, Y., Saito, I., and Takeshita, A.
Adenovirus-mediated arterial gene transfer does not require prior injury for submaximal gene expression. Gene Ther, 2: 351-354, 1995.

60.
Ohashi, T., Watabe, K., Sato, Y., Saito, I., Barranger, J. A., and Eto, Y.
Successful transduction of oligodendrocytes and restoration of arylsulfatase A deficiency in metachromatic leukodystrophy fibroblasts using an adenovirus vector. Gene Ther, 2: 443-449, 1995.

61.
Suzuki, R., Matsuura, Y., Suzuki, T., Ando, A., Chiba, J., Harada, S., Saito, I., and Miyamura, T.
Nuclear localization of the truncated hepatitis C virus core protein with its hydrophobic C terminus deleted. J Gen Virol, 76: 53-61, 1995.

62.
Tsukui, T., Miyake, S., Azuma, S., Ichise, H., Saito, I., and Toyoda, Y.
Gene transfer and expression in mouse preimplantation embryos by recombinant adenovirus vector. Mol Reprod Dev, 42: 291-297, 1995.

63.
Ueno, H., Li, J. J., Tomita, H., Yamamoto, H., Pan, Y., Kanegae, Y., Saito, I., and Takeshita, A.
Quantitative analysis of repeat adenovirus-mediated gene transfer into injured canine femoral arteries. Arterioscler Thromb Vasc Biol, 15: 2246-2253, 1995.

64.
Yamaguchi, S., Wakimoto, H., Yoshida, Y., Kanegae, Y., Saito, I., Aoyagi, M., Hirakawa, K., Amagasa, T., and Hamada, H.
Enhancement of retrovirus-mediated gene transduction efficiency by transient overexpression of the amphotropic receptor, GLVR-2. Nucleic Acids Res, 23: 2080-2081, 1995.

65.
Yoshida, M., Sakuma, J., Hayashi, S., Abe, K., Saito, I., Harada, S., Sakatani, M., Yamamoto, S., Matsumoto, N., Kaneda, Y., and et al.
A histologically distinctive interstitial pneumonia induced by overexpression of the interleukin 6, transforming growth factor beta 1, or platelet-derived growth factor B gene. Proc Natl Acad Sci U S A, 92: 9570-9574, 1995.



【1990〜1994】
1.
Aizaki, H., Watanabe, Y., Sarashina, T., Sakurai, T., Nagamori, S., Suzuki, T., Matsuura, Y., Saito, I., and Miyamura, T.
Genotyping of heapatitis C virus by simple ELISA method. Clinical and Diagnostic Virology, 3: 105-109, 1994.

2.
Kanegae, Y., Makimura, M., and Saito, I.
A simple and efficient method for purification of infectious recombinant adenovirus. Jpn J Med Sci Biol, 47: 157-166, 1994.

3.
Kim, D. W., Suzuki, R., Harada, T., Saito, I., and Miyamura, T.
Trans-suppression of gene expression by hepatitis C viral core protein. Jpn J Med Sci Biol, 47: 211-220, 1994.

4.
Matsuura, Y., Suzuki, T., Suzuki, R., Sato, M., Aizaki, H., Saito, I., and Miyamura, T.
Processing of E1 and E2 glycoproteins of hepatitis C virus expressed in mammalian and insect cells. Virology, 205: 141-150, 1994.

5.
Nakamura, Y., Wakimoto, H., Abe, J., Kanegae, Y., Saito, I., Aoyagi, M., Hirakawa, K., and Hamada, H.
Adoptive immunotherapy with murine tumor-specific T lymphocytes engineered to secrete interleukin 2. Cancer Res, 54: 5757-5760, 1994.

6.
Sakamoto, H., Ochiya, T., Sato, Y., Tsukamoto, M., Konishi, H., Saito, I., Sugimura, T., and Terada, M.
Adenovirus-mediated transfer of the HST-1 (FGF4) gene induces increased levels of platelet count in vivo. Proc Natl Acad Sci U S A, 91: 12368-12372, 1994.

7.
Kim, D. W., Harada, T., Saito, I., and Miyamura, T.
An efficient expression vector for stable expression in human liver cells. Gene, 134: 307-308, 1993.

8.
Matsuura, Y., Suzuki, R., Watanabe, Y., Suzuki, T., Miyamura, T., Kohara, M., Harada, S., and Saito, I.
Expression of E1 and E2/NS1 proteins of HCV in mammalian and insect cells. Vaccines93: Modern approaches to new vaccines including prevention of AIDS. Ginsberg, H.S., Brown, F., Chanock, R.M., and Lerner, R.A. (eds). Cold Spring Harbor Laboratory Press, New York, U.S.A. pp. 289-294. In, 1993.

9.
Miyake, S., Okishio, N., Samejima, I., Hiraoka, Y., Toda, T., Saito, I., and Yanagida, M.
Fission yeast genes nda1+ and nda4+, mutations of which lead to S-phase block, chromatin alteration and Ca2+ suppression, are members of the CDC46/MCM2 family. Mol Biol Cell, 4: 1003-1015, 1993.

10.
Sarashina, T., Sakurai, T., Watanabe, Y., Kashima, K., Suzuki, T., Chiba, J., Kita, Y., Horiuchi, T., Saito, I., and Miyamura, T.
Nucleotide sequence of the hepatitis C virus genome from a patient negative for anti-HCV by the first generation antibody assay. Nucleic Acids Res, 21: 1037, 1993.

11.
Ueno, T., Miyamura, T., Saito, I., and Mizuno, K.
Immortalization of differentiated human hepatocytes by a combination of a viral vector and collagen gel culture. Hum Cell, 6: 126-136, 1993.

12.
Dourakis, S., Brown, J., Kumar, U., Karayiannis, P., Kernoff, P., Chiba, J., Ohba, H., Miyamura, T., Saito, I., Monjardino, J., and et al.
Serological response and detection of viraemia in acute hepatitis C virus infection. J Hepatol, 14: 370-376, 1992.

13.
Inoue, Y., Suzuki, R., Matsuura, Y., Harada, S., Chiba, J., Watanabe, Y., Saito, I., and Miyamura, T.
Expression of the amino-terminal half of the NS1 region of the hepatitis C virus genome and detection of an antibody to the expressed protein in patients with liver diseases. J Gen Virol, 73: 2151-2154, 1992.

14.
Inoue, Y., Takeuchi, K., Chou, W. H., Unayama, T., Takahashi, K., Saito, I., and Miyamura, T.
Silent mother-to-child transmission of hepatitis C virus through two generations determined by comparative nucleotide sequence analysis of the viral cDNA. J Infect Dis, 166: 1425-1428, 1992.

15.
Katayama, T., Mazda, T., Kikuchi, S., Harada, S., Matsuura, Y., Chiba, J., Ohba, H., Saito, I., and Miyamura, T.
Improved serodiagnosis of non-A, non-B hepatitis by an assay detecting antibody to hepatitis C virus core antigen. Hepatology, 15: 391-394, 1992.

16.
Kikuchi, T., Onji, M., Michitaka, K., Saito, I., Miyamura, T., and Ohta, Y.
Anti-HCV immunoglobulin M antibody in patients with hepatitis C. J Gastroenterol Hepatol, 7: 246-248, 1992.

17.
Kohara, M., Tsukiyama-Kohara, K., Maki, N., Asano, K., Yamaguchi, K., Miki, K., Tanaka, S., Hattori, N., Matsuura, Y., Saito, I., and et al.
Expression and characterization of glycoprotein gp35 of hepatitis C virus using recombinant vaccinia virus. J Gen Virol, 73: 2313-2318, 1992.

18.
Matsuura, Y., Harada, S., Suzuki, R., Watanabe, Y., Inoue, Y., Saito, I., and Miyamura, T.
Expression of processed envelope protein of hepatitis C virus in mammalian and insect cells. J Virol, 66: 1425-1431, 1992.

19.
Boonmar, S., Takeuchi, K., Kubo, Y., Katayama, T., Harada, H., Ohbayashi, A., Choo, Q.-L., Kuo, G., Houghton, M., Saito, I., and Miyamura, T.
Molecular cloning of hepatitis C virus cDNA from plasma of an implicated donor of post-transfusion non-A, non-B hepatitis. Viral hepatitis and liver diseases, Hollinger, F. B. (ed). Alan R. Liss Co, Ltd., pp. 371-374. In, 1991.

20.
Chiba, J., Ohba, H., Matsuura, Y., Watanabe, Y., Katayama, T., Kikuchi, S., Saito, I., and Miyamura, T.
Serodiagnosis of hepatitis C virus (HCV) infection with an HCV core protein molecularly expressed by a recombinant baculovirus. Proc Natl Acad Sci U S A, 88: 4641-4645, 1991.

21.
Chou, W. H., Sheu, L., Cheng, S. F., Sheu, S. H., Lu, C. F., Saito, I., Miyamura, T., Lin, S. Y., and Wu, J. S.
Molecular cloning of cDNA of hepatitis C virus (HCV) genome from a healthy carrier in an aboriginal community in Taiwan with high prevalence of HCV infection. Jpn J Med Sci Biol, 44: 147-157, 1991.

22.
Chou, W. H., Yoneyama, T., Takeuchi, K., Harada, H., Saito, I., and Miyamura, T.
Discrimination of hepatitis C virus in liver tissues from different patients with hepatocellular carcinomas by direct nucleotide sequencing of amplified cDNA of the viral genome. J Clin Microbiol, 29: 2860-2864, 1991.

23.
Harada, S., Watanabe, Y., Takeuchi, K., Suzuki, T., Katayama, T., Takebe, Y., Saito, I., and Miyamura, T.
Expression of processed core protein of hepatitis C virus in mammalian cells. J Virol, 65: 3015-3021, 1991.

24.
Inoue, Y., Miyamura, T., Unayama, T., Takahashi, K., and Saito, I.
Maternal transfer of HCV. Nature, 353: 609, 1991.

25.
Kajino, K., Ohta, Y., Miyamura, T., and Saito, I.
Efficient cloning of hepatitis B virus DNA from single-stranded replicative intermediates and its application to S1 mapping of viral RNA in human liver tissue. J Med Virol, 33: 33-38, 1991.

26.
Kim, C. M., Koike, K., Saito, I., Miyamura, T., and Jay, G.
HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature, 351: 317-320, 1991.

27.
Michitaka, K., Onji, M., Horiike, N., Kajino, K., Saito, I., Miyamura, T., and Ohta, Y.
Intrafamilial transmission of hepatitis C virus in Japan. Gastroenterol Jpn, 26: 619-622, 1991.

28.
Miyamura, T., Saito, I., Yoneyama, T., Takeuchi, K., Ohbayashi, A., Watanabe, Y., Choo, Q.-L., Houghton, M., and Kuo, G.
Role of hepatitis C virus in hepatocellular carcinoma. Viral hepatitis and liver diseases, Hollinger, F. B. (ed)., Alan R. Liss Co, Ltd., pp. 559-562. In, 1991.

29.
Miyamura, T., Takeuchi, K., Takebe, Y., Harada, S., Matsuura, Y., Watanabe, Y., Yoneyama, T., Saito, I., and Chiba, J.
Cloning and expression of the structural gene of hepatitis-C virus obtained from healthy virus carriers in Japan. Vaccines 91: Modern approaches to new vaccines including prevention of AIDS. Brown, F., Chanock, R. M., Ginsberg, H. S., and Lerner, R. A. (eds). Cold Spring Harbor Laboratory Press, New York, USA., pp. 227-231. In, 1991.

30.
Onji, M., Kikuchi, T., Michitaka, K., Saito, I., Miyamura, T., and Ohta, Y.
Detection of hepatitis C virus antibody in patients with autoimmune hepatitis and other chronic liver diseases. Gastroenterol Jpn, 26: 182-186, 1991.

31.
Watanabe, Y., Harada, S., Saito, I., and Miyamura, T.
Prevalence of antibody against the core protein of hepatitis C virus in patients with hepatocellular carcinoma. Int J Cancer, 48: 340-343, 1991.

32.
Yuasa, T., Kajino, K., Saito, I., and Miyamura, T.
Preferential expression of the large hepatitis B virus surface antigen gene by an adenovirus-hepatitis B virus recombinant. J Gen Virol, 72: 1927-1934, 1991.

33.
Boonmar, S., Pojanagaroon, B., Watanabe, Y., Tanaka, Y., Saito, I., and Miyamura, T.
Prevalence of hepatitis C virus antibody among healthy blood donors and non-A, non-B hepatitis patients in Thailand. Jpn J Med Sci Biol, 43: 29-36, 1990.

34.
Hino, O., Nomura, K., Ohtake, K., Saito, I., Abe, K., Rogler, C. E., Sugano, H., and Kitagawa, T.
Development of transgenic mice containing woodchuck hepatitis virus DNA. Gastroenterol Jpn, 25: 53-56, 1990.

35.
Katayama, T., Kikuchi, S., Tanaka, Y., Saito, I., Miyamura, T., Choo, Q. L., Houghton, M., and Kuo, G.
Blood screening for non-A, non-B hepatitis by hepatitis C virus antibody assay. Transfusion, 30: 374-376, 1990.

36.
Miyamura, T., Saito, I., Katayama, T., Kikuchi, S., Tateda, A., Houghton, M., Choo, Q. L., and Kuo, G.
Detection of antibody against antigen expressed by molecularly cloned hepatitis C virus cDNA: application to diagnosis and blood screening for posttransfusion hepatitis. Proc Natl Acad Sci U S A, 87: 983-987, 1990.

37.
Saito, I., Miyamura, T., Ohbayashi, A., Harada, H., Katayama, T., Kikuchi, S., Watanabe, Y., Koi, S., Onji, M., Ohta, Y., and et al.
Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proc Natl Acad Sci U S A, 87: 6547-6549, 1990.

38.
Suzuki, T., Kajino, K., Masui, N., Saito, I., and Miyamura, T.
Alternative splicing of hepatitis B virus RNAs in HepG2 cells transfected with the viral DNA. Virology, 179: 881-885, 1990.

39.
Takeuchi, K., Boonmar, S., Kubo, Y., Katayama, T., Harada, H., Ohbayashi, A., Choo, Q. L., Kuo, G., Houghton, M., Saito, I., and et al.
Hepatitis C viral cDNA clones isolated from a healthy carrier donor implicated in post-transfusion non-A, non-B hepatitis. Gene, 91: 287-291, 1990.

40.
Takeuchi, K., Kubo, Y., Boonmar, S., Watanabe, Y., Katayama, T., Choo, Q. L., Kuo, G., Houghton, M., Saito, I., and Miyamura, T.
The putative nucleocapsid and envelope protein genes of hepatitis C virus determined by comparison of the nucleotide sequences of two isolates derived from an experimentally infected chimpanzee and healthy human carriers. J Gen Virol, 71: 3027-3033, 1990.

41.
Takeuchi, K., Kubo, Y., Boonmar, S., Watanabe, Y., Katayama, T., Choo, Q. L., Kuo, G., Houghton, M., Saito, I., and Miyamura, T.
Nucleotide sequence of core and envelope genes of the hepatitis C virus genome derived directly from human healthy carriers. Nucleic Acids Res, 18: 4626, 1990.

42.
Yoneyama, T., Takeuchi, K., Watanabe, Y., Harada, H., Ohbayashi, A., Tanaka, Y., Yuasa, T., Saito, I., and Miyamura, T.
Detection of hepatitis C virus cDNA sequence by the polymerase chain reaction in hepatocellular carcinoma tissues. Jpn J Med Sci Biol, 43: 89-94, 1990.



【1985〜1989】
1.
Kamitsukasa, H., Harada, H., Yakura, M., Fukuda, A., Ohbayashi, A., Saito, I., Miyamura, T., Choo, Q. L., Houghton, M., and Kuo, G.
Intrafamilial transmission of hepatitis C virus [letter] [see comments]. Lancet, 2: 987, 1989.

2.
Kubo, Y., Takeuchi, K., Boonmar, S., Katayama, T., Choo, Q. L., Kuo, G., Weiner, A. J., Bradley, D. W., Houghton, M., Saito, I., and et al.
A cDNA fragment of hepatitis C virus isolated from an implicated donor of post-transfusion non-A, non-B hepatitis in Japan. Nucleic Acids Res, 17: 10367-10372, 1989.

3.
Onji, M., Lever, A. M., Saito, I., and Thomas, H. C.
Defective response to interferons in cells transfected with the hepatitis B virus genome. Hepatology, 9: 92-96, 1989.

4.
Saito, I., Groves, R., Giulotto, E., Rolfe, M., and Stark, G. R.
Evolution and stability of chromosomal DNA coamplified with the CAD gene. Mol Cell Biol, 9: 2445-2452, 1989.

5.
Suzuki, T., Masui, N., Kajino, K., Saito, I., and Miyamura, T.
Detection and mapping of spliced RNA from a human hepatoma cell line transfected with the hepatitis B virus genome. Proc Natl Acad Sci U S A, 86: 8422-8426, 1989.

6.
Debatisse, M., Saito, I., Buttin, G., and Stark, G. R.
Preferential amplification of rearranged sequences near amplified adenylate deaminase genes. Mol Cell Biol, 8: 17-24, 1988.

7.
Ikeda, H., Trowsdale, J., and Saito, I.
Mulcos: a vector for amplification and simultaneous expression of two foreign genes in mammalian cells. Gene, 71: 19-27, 1988.

8.
Giulotto, E., Saito, I., and Stark, G. R.
Structure of DNA formed in the first step of CAD gene amplification. Embo J, 5: 2115-2121, 1986.

9.
Kuge, S., Saito, I., and Nomoto, A.
Primary structure of poliovirus defective-interfering particle genomes and possible generation mechanisms of the particles. J Mol Biol, 192: 473-487, 1986.

10.
Saito, I., Oya, Y., and Shimojo, H.
Novel RNA family structure of hepatitis B virus expressed in human cells, using a helper-free adenovirus vector. J Virol, 58: 554-560, 1986.

11.
Saito, I. and Stark, G. R.
Charomids: cosmid vectors for efficient cloning and mapping of large or small restriction fragments. Proc Natl Acad Sci U S A, 83: 8664-8668, 1986.

12.
Saito, I., Oya, Y., Yamamoto, K., Yuasa, T., and Shimojo, H.
Construction of nondefective adenovirus type 5 bearing a 2.8-kilobase hepatitis B virus DNA near the right end of its genome. J Virol, 54: 711-719, 1985.


【1980〜1984】
1.
Fukui, Y., Saito, I., Shiroki, K., and Shimojo, H.
Isolation of transformation-defective, replication-nondefective early region 1B mutants of adenovirus 12. J Virol, 49: 154-161, 1984.

2.
Fukui, Y., Shiroki, K., Saito, I., and Shimojo, H.
Characterization of a host range mutant of human adenovirus 12 defective in early region 1B. J Virol, 50: 132-136, 1984.

3.
Shiroki, K., Hashimoto, S., Saito, I., Fukui, Y., Kato, H., and Shimojo, H.
Expression of the E4 gene is required for establishment of soft-agar colony-forming rat cell lines transformed by the adenovirus 12 E1 gene. J Virol, 50: 854-863, 1984.

4.
Fukui, Y., Saito, I., Shiroki, K., Shimojo, H., Takebe, Y., and Kaziro, Y.
The 19-kDal protein encoded by early region 1b of adenovirus type 12 is synthesized efficiently in Escherichia coli only as a fused protein. Gene, 23: 1-13, 1983.

5.
Oda, K., Fukui, Y., Saito, I., Masuda, M., Shiroki, K., and Shimojo, H.
Hyperproduction of adenovirus type 12 E1B gene product in monkey cells, using a simian virus 40 vector. J Virol, 45: 420-427, 1983.

6.
Oda, K., Kato, H., Saito, I., Sugano, S., Maruyama, K., Masuda, M., Shiroki, K., and Shimojo, H.
Expression of adenovirus type 12 E1A gene in monkey cells, using a simian virus 40 vector. J Virol, 45: 408-419, 1983.

7.
Saito, I., Shiroki, K., and Shimojo, H.
mRNA species and proteins of adenovirus type 12 transforming regions: identification of proteins translated from multiple coding stretches in 2.2 kb region 1B mRNA in vitro and in vivo. Virology, 127: 272-289, 1983.

8.
Shiroki, K., Saito, I., Maruyama, K., Fukui, Y., Imatani, Y., Oda, K. I., and Shimojo, H.
Expression of adenovirus type 12 early region 1 in KB cells transformed by recombinants containing the gene. J Virol, 45: 1074-1082, 1983.

9.
Shiroki, K., Saito, I., Maruyama, K., and Shimojo, H.
Isolation of a nondefective recombinant between adenovirus type 5 and early region 1A of adenovirus type 12. J Virol, 46: 632-637, 1983.

10.
Shiroki, K., Maruyama, K., Saito, I., Fukui, Y., Yazaki, K., and Shimojo, H.
Dependence of tumor-forming capacities of cells transformed by recombinants between adenovirus types 5 and 12 on expression of early region 1. J Virol, 42: 708-718, 1982.

11.
Saito, I., Sato, J., Handa, H., Shiroki, K., and Shimojo, H.
Mapping of RNAs transcribed from adenovirus type 12 early and VA RNA regions. Virology, 114: 379-398, 1981.

12.
Shiroki, K., Maruyama, K., Saito, I., Fukui, Y., and Shimojo, H.
Incomplete transformation of rat cells by a deletion mutant of adenovirus type 5. J Virol, 38: 1048-1054, 1981.

13.
Segawa, K., Saito, I., Shiroki, K., and Shimojo, H.
In vitro translation of adenovirus type 12-specific mRNA complementary to the transforming gene. Virology, 107: 61-70, 1980.

14.
Shiroki, K., Segawa, K., Saito, I., Shimojo, H., and Fujinaga, K.
Products of the adenovirus-12 transforming genes and their functions. Cold Spring Harb Symp Quant Biol, 44: 533-540, 1980.

15.
Sugisaki, H., Sugimoto, K., Takanami, M., Shiroki, K., Saito, I., Shimojo, H., Sawada, Y., Uemizu, Y., Uesugi, S., and Fujinaga, K.
Structure and gene organization in the transformed Hind III-G fragment of Ad12. Cell, 20: 777-786, 1980.