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2000

  1. Y. Utada, S. Haga, T. Kajiwara, F. Kasumi, F. Akiyama, G. Sakamoto, Y. Nakamura, and M. Emi: Allelic loss at the 8p22 region as a prognostic factor in large and estrogen receptor negative breast carcinomas. Cancer, 88:1410-1416, 2000
  2. Y. Utada, S. Haga, T. Kajiwara, F. Kasumi, F. Akiyama, G. Sakamoto, Y. Nakamura, and M. Emi: Mapping of target regions of allelic loss in primary breast cancers to 1-cM intervals on genomic contigs at 6q21 and 6q25.3. Jpn. J. Cancer Research, 91:293-300, 2000
  3. S. Isaka, Y. Takei, T. Tokino, Y. Miyoshi, K. Koyama, M. Suzuki, E. Takahashi, C. Azuma, Y. Murata, and Y. Nakamura: Isolation and characterization of a nobel TP53-inducible gene, TP53TG5, which suppresses growth and shows cell cycle-dependent transition of expression. Genes Chromosomes and Cancer, 27:345-352, 2000
  4. T. Tokino, Y. Nakamura: The role of p53-target genes in human cancer. Crinical reviews in Oncology/Hematology, 33:1-6, 2000
  5. H. Nakagawa, K. Koyama, Y. Murata, M. Morito, T. Akiyama,and Y. Nakamura: EB3, a novel member of the EB1 family preferentially expressed in the central nervous system, binds to a CNS-specific APC homologue. Oncogene, 19:210-216, 2000
  6. T. Nishiwaki, Y. Daigo, T. Kawasoe, and Y. Nakamura: Isolation and mutational analysis of a novel human cDNA, DEC1 (deleted in esophageal cancer 1), derived from the tumor suppressor locus in 9q32. Genes Chromosomes and Cancer, 27:169-176, 2000
  7. H. Akashi, H.-J. Han, M. Iizaka, Y. Nakajima, S. Sugano, K. Imai and Y. Nakamura: Isolation and characterization of a human cDNA encoding a protein homologous to the 7.2-kDa protein (subunit X) of bovine ubiquinol-cytochrome C reductase. Journal of Human Genetics, 45:43-46, 2000
  8. H. Nakagawa, K. Koyama, Y. Murata, M. Morito, T. Akiyama, Y. Nakamura: APCL, a CNS-specific homologue of APC, Binds to p53-Binding protein 2 and translocates it to the perinucleus. Cancer Research, 60:101-105, 2000
  9. T. Kinjo, M. Isomura, T. Iwamasa, and Y. Nakamura: Molecular cloning and characterization of two novel genes on chromosome 8p21.3. Journal of Human Genetics, 45:12-17, 2000
  10. M. Iizaka, H.-J. Han, H. Akashi, Y. Nakajima, S. Sugano, M. Ogawa, and Y. Nakamura: Isolation and chromosomal assignment of a novel human gene, CORO1C, homologous to coronin-like actin-binding proteins. Cytogenetics Cell Genetics, 88:221-224, 2000
  11. C. Kihara, T. Seki, Y. Furukawa, H. Yamana, Y. Kimura, P. van Schaardenburgh, K. Hirata, and Y. Nakamura: Mutations in zinc-binding domains of p53 as a prognostic marker of esophageal-cancer patients. Jpn. J. Cancer Research, 91:190-198, 2000
  12. H. Akashi, H.-J. Han, M. Iizaka, Y. Nakajima, Y. Furukawa, S. Sugano, K. Imai and Y. Nakamura: Isolation and characterization of a novel gene encoding a putative seven-span transmembrane protein, TM7SF3. Cytogenetics Cell Genetics, 88:305-309, 2000
  13. T. Oyama, Y. Miyoshi, K. Koyama, H. Nakagawa, T. Yamori, T. Ito, H. Matsuda and Y. Nakamura: Isolation of a novel gene on 8p21.3-22 whose expression is reduced significantly in human colorectal cancers with liver metastasis. Genes Chromosomes and Cancer, 29:9-15, 2000
  14. S. Satoh, Y. Daigo, Y. Furukawa, T. Katoh, N. Miwa, T. Nishiwaki, T. Kawasoe, H. Ishiguro, M. Fujita, T. Tokino, Y. Sasaki, S. Imaoka, M. Murata, T. Shimano, Y. Yamaoka, and Y. Nakamura: AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Nature Genetics, 24:245-250, 2000
  15. R. Yamada, T. Tanaka, Y. Ohnishi, K. Suematsu, M. Minami, T. Seki, S. Tohma, K. Yamamoto, Y. Nakamura: Identification of 142 single nucleotide polymorphisms in 41 candidate genes for rheumatoid arthritis in the Japanese population. Human Genetics, 106:293-297, 2000
  16. Y. Ohnishi, T. Tanaka , R. Yamada , K. Suematsu, M. Minami, K. Fujii , N. Hoki , K. Kodama , S. Nagata , T. Hayashi , N. Kinoshita , H Sato, H. Sato, T. Kuzuya, H. Takeda, M. Hori, and Y. Nakamura: Identification of 187 single nucleotide polymorphisms (SNPs) among 41 candidate genes for ischemic heart disease in the Japanese population. Human Genetics, 106:288-292, 2000
  17. M. Futamura, H. Arakawa, K. Matsuda, T. Katagiri, S. Saji, Y. Miki and Y. Nakamura: Potential role of BRCA2 in a mitotic checkpoint after phosphorylation by hBUBR1. Cancer Research, 60:1531-1535, 2000
  18. H. Iwasa, T. Itoh, R. Nagai, Y. Nakamura, and T. Tanaka: Twenty single nucleotide polymorphisms (SNPs) and their alleleic frequencies in four genes that are responsible for familial long QT syndrome in the Japanese population. Journal of Human Genetics, 45:182-183, 2000
  19. M. Unoki, S. Furuta, Y. Onouchi, O. Watanabe, S. Doi, H. Fujiwara, A. Miyatake, K. Fujita, M. Tamari and Y. Nakamura: Association studies of 33 single nucleotide polymorphisms (SNPs) in 29 candidate genes for bronchial asthma: Positive association of a T924C polymorphism in the thromboxane A2 receptor gene. Human Genetics, 106:440-446, 2000
  20. Z.-Q. Yang, M.A. Yoshida, Y. Fukuda, N. Kurihara, Y. Nakamura, and J. Inazawa: Molecular cytogenetic analysis of 17 renal cancer cell lines: Increased copy number at 5q31-33 in cell lines from nonpapillary carcinomas. Jpn. J. Cancer Research, 91:156-163, 2000
  21. H. Tanaka, H. Arakawa, T. Yamaguchi, K. Shiraishi, S. Fukuda, K. Matsui, Y. Takei, and Y. Nakamura: A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint DNA damage. Nature, 404:42-49, 2000
  22. H. Ishiguro, Y. Furukawa, Y. Daigo, Y. Miyoshi, Y. Nagasawa, T. Nishiwaki, T. Kawasoe, M. Fujita, S. Satoh,１ N. Miwa, Y. Fujii, and Y. Nakamura: Isolation and characterization of human NBL4, a gene involved in the β-catenin/Tcf signaling pathway. Jpn. J. Cancer Research, 91:597-603, 2000
  23. Y.-M. Lin, T. kato, S. Satoh, Y. Nakamura and Y. Furukawa: Identification of novel polymorphisms in the AXIN1 and CDX-2 genes. Journal of Human Genetics, 45:254-256, 2000
  24. K. Shiraishi, S. Fukuda, T. Mori, K. Matsuda, T. Yamaguchi, C. Tanikawa, M. Ogawa, Y. Nakamura and H. Arakawa: Identification of fractalkine, a CX3C-type chemokine, as a direct target of p53. Cancer Research, 60:3722-3726, 2000
  25. L. C. McCarthy , M.-T. Bihoreau, S. L. Kiguwa, J. Browne, T. K. Watanabe, H. Hishigaki, A. Tsuji, S. Kiel, C. Webber, M. E. Davis, C. Knights, A. Smith, R. Critcher, P. Huxtall, J. R. Hudson, Jr., T. Ono, H. Hayashi, T. Takagi, Y. Nakamura, A. Tanigami, P. N. Goodfellow, G. M. Lathrop and M. R. James: A whole-genome radiation hybrid panel andframework map of the rat genome. Mammalian Genome, 11:791-795, 2000
  26. T. Kawasoe, Y. Furukawa, Y. Daigo, T. Nishiwaki, H. Ishiguro, M. Fujita, S. Satoh, N. Miwa, Y. Nagasawa, Y. Miyoshi, M. Ogawa and Y. Nakamura: Isolation and characterization of a novel human gene, DRCTNNB1A, the expression of which is down-regulated by β-catenin. Cancer Research, 60:3354-3358, 2000
  27. M. Nakanishi, C. Sakakura, Y. Fujita, R. Yasuoka, H. Aragane, K. Koide, A. Hagiwara, T. Yamaguchi, Y. Nakamura, T. Abe, J. Inazawa, and H. Yamagishi: Genomic alterations in primary gastric cancers analyzed by comparative genomic hybridization and clinicopathological factors. Hepato-Gastroenterology, 47:658-662, 2000
  28. T.K. Watanabe, T. Ono, S. Okuno, A. Mizoguchi-Miyashita, Y. Yamasaki, N. Kanemoto, H. Hishigaki, K. Oga, E. Takahashi, Y. Irie, M. Bihoreau, M. R. James, G.M. lathrop, T. Takagi, Y. Nakamura, and A. Tanigami: Characterization of newly developed SSLP markers for the rat. Mammalian Genome, 11:300-305, 2000
  29. M. Higashiyama, Y. Miyoshi, K. Kodama, H. Yokouchi, K. Takami, M. Nishijima, T. Nakayama, H. Kobayashi, K. Minamigawa, and Y. Nakamura: p53-regulated GML gene expression in non-small cell lung cancer: a promising relationship to cisplatin chemosensitivity. Europian Journal of Cancer, 36:489-495, 2000
  30. M. Horie, Y. Mitsumoto, H. Kyushiki, N. Kanemoto, A. Watanabe, Y. Taniguchi, N. Nishino, T. Okamoto, M. Kondo, T. Mori, K. Noguchi, Y. Nakamura, E. Takahashi, and A. Tanigami: Identification and characterization of TMEFF2, a novel survival factor for hippocampal and mesencephalic neurons. Genomics, 67:146-152, 2000
  31. M. Murata, K. Iwao, Y. Miyoshi, Y. Nagasawa, M. Yabu, S. Himeno, K. Imanishi, M. Ohsawa, H. Wada, S. Tominaga, T. Shimano, T. Kobayashi, and Y. Nakamura: Activation of β-catenin gene by interstitial deletions involving exon 3 as an early event in colorectal tumorigenesis. Cancer Letters, 159:73-78, 2000
  32. H. Akashi, H.-J. Han, M. Iizaka, and Y. Nakamura: Growth-suppressive effect of NSAIDs on 11 colon-cancer cell lines and fluorescence differential display of genes whose expression is influenced by sulindac. Int. J. Cancer, 88:873-880, 2000
  33. T. Yamauchi, M. Tada, K. Houkin. T. Tanaka, Y. Nakamura, S. Kuroda, H. Abe. T. Inoue, K. Ikezaki, T. Matsushima, M. Fukui: Linkage of familial Moyamoya disease (spotaneous occlusion of the circle of Willis) to chromosome 17q25. Stroke, 31:930-935, 2000
  34. S. Matsumoto, K. Minobe, Y. Utada, K. Furukawa, M. Onda, G. Sakamoto, F. Kasumi, Y. Nakamura, and M. Emi: Loss of heterozygosity at 3p24-p25 as a prognostic factor in breast cancer. Cancer Letters, 152:63-69, 2000
  35. W.-M. Qu, T. Miyazaki, M. Terada, L.-M. Lu, M. Nishihara, A. Yamada, S. Mori, Y. Nakamura, H. Ogasawara, C. Yazawa, S. Nakatsuru, and M. Nose: Genetic dissection of vasculitis in MRL/lpr lupus mice: a novel susceptibility locus involving the CD72c Allele. Eur. J. Immunolo., 30:2027-2037, 2000
  36. M. Murata, K. Iwao, Y. Miyoshi, Y. Nagasawa, T. Ohta, K. Shibata, K. Oda, H. Wada, S. Tominaga, Y. Matsuda, M. Ohsawa, Y. Nakamura and T. Shimano: Molecular and biological analysis of carcinoma of the samll intestine: βcatenin gene mutation by interstitial deletion involving exon 3 and replication error phenotype. Am. J. Gastroenterology, 95:1576-1580, 2000
  37. K. Ono, T. Tanaka, T. Tsunoda, O. Kitahara, C. Kihara, A. Okamoto, K. Ochiai, T. Takagi, and Y. Nakamura: Identification by cDNA microarray of genes Involved in ovarian carcinogenesis. Cancer Research, 60:5007-5011, 2000
  38. T. Seki, T. Tanaka, and Y. Nakamura: Genomic structure and multiple single-nucleotide polymorphisms (SNPs) of the thiopurine S-methyltransferase (TPMT) gene. Journal of Human Genetics, 45:299-302, 2000
  39. K. Oda, H. Arakawa, T. Tanaka, K. Matsuda, C. Tanikawa, T. Mori, H. Nishimori, K. Tamai, T. Tokino, Y. Nakamura, and Y. Taya: p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell, 102:849-862, 2000
  40. K. Yamada, H. Tomita, K. Yoshiura, S. Kondo, K. Wakui, Y. Fukushima, S. Ikegawa, Y. Nakamura, T. Amemiya, and N. Niikawa: An autosomal dominant posterior polar cataract locus maps to human chromosome 20p12-q12. Eur. J. Human Genetics, 8:535-539, 2000
  41. Y. Utada, M. Emi, S. Haga, M. Yoshomoto, F. Kasumi, F. Akiyama, G. Sakamoto, S. Haga, T. Kajiwara, and Y. Nakamura: Allelic loss at 1p34-36 predict poor prognosis in node-negative breast cancer. Clinical Cancer Research, 6:3193-3198, 2000
  42. Z.-Q. Yang, I. Imoto, Y. Fukuda, A. Pimkhaokham, Y. Shimada, M. Imamura, S. Sugano, Y. Nakamura, and J. Inazawa: Identification of a novel gene, GASC1, with an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines. Cancer Research, 60:4735-4739, 2000
  43. M.-S. Wu, K. Tani, H. Sugiyama, H. Hibino, K. Izawa, T. Tanabe, Y. Nakazaki, H. Ishii, J. Ohashi, H. Hohjoh, T. Iseki, A. Tojo, Y. Nakamura, Y. Tanioka, K. Tokunaga, and S. Asano: MHC (Major Histocompatibility Complex)-DRB genes and polymorphisms in common marmoset. Journal of Molecular Evolution, 51:214-222, 2000
  44. A. Pimkhaokham, Y. Shimada, Y. Fukuda, N. Kurihara, I. Imoto, Z.-Q. Yang, M. Imamura, Y. Nakamura, and J. Inazawa: Nonrandoom chromosomal imbalances in esophageal squamous cell carcinoma cell lines: possible involvement of the ATF3 and CENPF genes in the 1q32 amplicon. Jpn. J. Cancer Research, 91:1126-1133, 2000
  45. J. Sasaki, K. Ishikawa, K. Kobayashi, E. Kondo-Iida, M. Fukuyama, H. Mizusawa, S. Takashima, Y. Sasakihara, Y. Nakamura, and T. Toda: Neuronal expression of the fukutin gene. Human Molecular Genetics, 9:3083-3090, 2000
  46. M.E. Nita, S.K. Ono-Nita, N. Tsuno, O. Tominaga, T. Takenoue, E. Sunami, J. Kitayama, Y. Nakamura, and H. Nagawa: Bcl-XL antisense sensitizes human colon cancer cell line to 5-fluorouracil. Jpn. J. Cancer Research, 91:825-832, 2000
  47. T. Nakajima, M. Kutabayashi, Y. Ohyama, Y. Kaneko, T. Furukawa, T. Itoh, Y. Taniguchi, T. Tanaka, Y. Nakamura, M. Hiraoka, and R. Nagai: Characterization of S818L mutation in HERG c-terminus in LQT2; Modification of activation-deactivation gating properties. FEBS Letters, 481:197-203, 2000
  48. M. Fujita, Y. Furukawa, Y. Nagasawa, M. Ogawa and Y. Nakamura: Down-regulation of monocyte chemotactic protein-3 (MCP-3) by activated β-catenin. Cancer Research, 60:6683-6687, 2000
  49. F. Kasai, E. Takahashi, K. Koyama, K. Terao, Y. Suto, K. Tokunaga, Y. Nakamura, and M. Hirai: Comparative FISH mapping of the ancestral fusion point of human chromosome 2. Chromosome Research, 8:727-735, 2000
  50. H. Ohigashi, O. Ishikawa, Y. Sasaki, T. Yamada, H. Furukawa, S. Imaoka, T. Kasugai, S. Ishiguro, K. Ueda, Y. Miyoshi, and Y. Nakamura: K-ras point mutation in the nerve plexuses around the superior mesenteric artery in respectable adenocarcinoma of the pancreatic head. Arch Surg., 135:1450-1455, 2000
  51. S. Ikegawa, M. Sano, Y. Koshizuka, and Y. Nakamura: Isolation, characterization, and mapping of the mouse and human PRG4 (proteoglycan 4) genes. Cytogenetics Cell Genetics, 90:291-297, 2000
  52. Y. Fukuda, N. Kurihara, I. Imoto, K. Yasui, M. Yoshida, K. Yanagihara, J.G. Park, Y. Nakamura, J. Inazawa: CD44 is a potential target of amplification within the 11p13 amplicon detected in gastric cancer cell lines. Genes Chromosomes and Cancer, 29:315-324, 2000
  53. M. Kato, K. Yano, F. Matsuo, H. Saito, T. Katagiri, H. Kurumizaka, M. Yoshimoto, F. Kasumi, F. Akiyama, G. Sakamoto, H. Nagawa, Y. Nakamura, and Y. Miki: Identification of Rad51 alteration in patients with bilateral breast cancer. Journal of Human Genetics, 45:133-137, 2000
  54. M. Sakamoto, J. Ono, S. Okada, Y. Nakamura, and H. Kurahashi: Genetic alteration of the DCX gene in Japanese patients with subcortical laminar heterotopia or isolated lissencephaly sequence. Journal of Human Genetics, 45:167-170, 2000
  55. Y. Nakatsuru, K. Minami, A. Yoshikawa, JJ. Zhu, H. Oda, P. Masahito, N. Okamoto, Y. Nakamura, T. Ishikawa: Eel WT1 sequence and expression in spontaneous nephroblastomas in Japanese eel. Gene, 245:245-251, 2000
  56. A. Iida, M. Emi, R. Matsuoka, E. Hiratsuka, K. Okui, H. Ohashi, J. Inazawa, Y. Fukushima, T. Imai, Y. Nakamura: Identification of a gene disrupted by inv(11)(q3.5;q25) in a patient with leftright axis malformation. Human Genetics, 106:277-287, 2000
  57. S. Ikegawa, H. Ohashi, T. Ogata, A. Honda, M. Tsukahara, T. Kubo, M. Kimizuka, M. Shimode, T. Hasegawa, G. Nishimura, Y. Nakamura: Novel and Recrrent EBP Mutations in X-Linked Dominant Chondrodysplasia Punctata. American journal of Medical Genetics, 94:300-305, 2000

    2001　　↑ページトップへ

  58. A. Hirano, Y. Utada, S. Haga, T. Kajiwara, G. Sakamoto, F. Kasumi, Y. Nakamura, and M. Emi: Allelic losses as prognostic markers for breast cancers. Int. J. Clin Oncology, 6:6-12, 2001
  59. K. Kyo, T. Muto, H. Nagawa, G. M. Lathrop, and Y. Nakamura: Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease. Journal of Human Genetics, 46:5-20, 2001
  60. H. Iwasa, M. Kurabayashi, R. Nagai, Y. Nakamura, and T. Tanaka: Multiple single-nucleotide polymorphisms (SNPs) in the Japanese population in six candidate genes for long QT syndrome. Journal of Human Genetics, 46:158-162, 2001
  61. O. Kitahara, Y. Furukawa, T. Tanaka, C. Kihara, K. Ono, R. Yanagawa, E. M. Nita, H. Ogasawara, J. Okutsu, H. Zenbutsu, N. Shiraishi, T. Takagi, Y. Nakamura, and T. Tsunoda: Alterations of gene expression during colorectal carcinogenesis revealed by cDNA microarrays after laser-capture microdissection of tumor tissues and normal epithelia. Cancer Research, 61:3544-3549, 2001
  62. T. Itoh, K. Kikuchi, Y. Odagawa, S. Takata, K. Yano, S. Okada, N. Haneda, S. Ogawa, O. Nakano, Y. Kawahara, H. Kasai, T. Nakayama, T. Fukutomi, H. Sakurada, A. Shimizu, Y. Yazaki, R. Nagai, Y. Nakamura, and T. Tanaka: Correlation of genetic etiology with response to β-adrenergic blockade among symptomatic patients with familial long-QT syndrome. Journal of Human Genetics, 46:38-40, 2001
  63. S. Takeoka, M. Unoki, Y. Onouchi, S. Doi, H. Fujiwara, A. Miyatake, K. Fujita, Ituro Inoue, Y. Nakamura, and M. Tamari: Amino-acid substitutions in the IKAP gene product significantly increase risk for bronchial asthma in children. Journal of Human Genetics, 46:57-63, 2001
  64. R. Yamada, T. Tanaka, M. Unoki T. Nagai, T. Sawada, Y. Ohnishi, T, Tsunoda, M. Yukioka, A. Maeda, K. Suzuki, H. Tateishi, T. Ochi, Y. Nakamura, and K. Yamamoto: Association between a single-nucleotide polymorphism in the promoter of the human interleukin-3 gene and rheumatoid arthritis in Japanese patients, and maximum-likelihood estimation of combinatorial effect that two genetic loci have on susceptibility to the disease. Am. J. Human Genetics, 68:674-685, 2001
  65. M. Matsushima-Nishiu, M. Unoki, K. Ono, T. Tsunoda, T. Minaguchi, H. Kuramoto, M. Nishida, T. Satoh, T. Tanaka, and Y. Nakamura: Growth and gene expression profiles analyses of endometrial cancer cells expressing exogenous PTEN. Cancer Research, 61:3741-3749, 2001
  66. T. Kato, S. Satoh, H. Okabe, O. Kitahara, K. Ono, C. Kihara, T. Tanaka, T. Tsunoda, Y. Yamaoka, Y. Nakamura, and Y. Furukawa: Isolation of a novel human gene, MARKL1, homologous to MARK3 and its involvement in hepatocellular carcinogenesis. Neoplasia, 3:4-9, 2001
  67. C. Suzuki, M. Unoki, and Y. Nakamura: Identification and allelic frequencies of novel single-nucleotide polymorphisms in the DUSP1 and BTG1 genes. Journal of Human Genetics, 46:155-157, 2001
  68. H. Okabe, S. Satoh, T. Kato, O. Kitahara, R. Yanagawa, Y. Yamaoka, T. Tsunoda, Y. Furukawa and Y. Nakamura: Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: identification of genes involved in viral carcinogenesis and tumor progression. Cancer Research, 6:2129-2137, 2001
  69. T. Watanabe, S. Okuno, T. Ono, Y. Yamasaki, K. Oga, A. Mizoguchi-Miyakita, H. Miyano, M. Suzuki, H. Momota, Y. Goto, H. Shinomiya, H. Hishigaki, I. Hayashi, T. Asai, S. Wakitani, T. Takagi, Y. Nakamura, and A. Tanigami: Single-allele correction of the Dmo1 locus in congenic animals substantially attenuates obesity, dyslipidaemia and diabetes phenotypes of the OLETF rat. Clin. and Exp. Pharmacology and Psysiology, 28:28-42, 2001
  70. A. Iida, A. Sekine, S. Saito, Y. Kitamura, T. Kitamoto, S. Osawa, C. Mishima and Y. Nakamura: Catalog of 320 single nucleotide polymorphisms (SNPs) in 20 quinone oxidoreductase and sulfotransferase genes. Journal of Human Genetics, 46:225-240, 2001
  71. O. Watanabe, M. Tamari, K. Natori, Y. Onouchi, Y. Shiomoto, I. Hiraoka and Y. Nakamura: Loci on murine chromosomes 7 and 13 that modify the phenotype of the NOA mouse, an animal model of atopic dermatitis. Journal of Human Genetics, 46:221-224, 2001
  72. A. Sekine, S. Saito, A. Iida, Y. Mitsunobu, S. Higuchi, S. Harigae, and Y. Nakamura: Identification of single-nucleotide polymorphisms (SNPs) of human N-acetyltransferase genes NAT1, NAT2, AANAT, ARD1 and L1CAM in the Japanese population. Journal of Human Genetics, 46:314-319, 2001
  73. S. Saito, A. Iida, A. Sekine, C. Eguchi, Y. Miura, and Y. Nakamura: Seventy genetic variations in human microsomal and soluble epoxide hydrolase genes (EPHX1 and EPHX2) in the Japanese population. Journal of Human Genetics, 46:325-329, 2001
  74. K. Kobayashi, J. Sasaki, E. Kondo-Iida, Y. Fukuda, M. Kinoshita, Y. Sunada, Y. Nakamura, and T. Toda: Structural organization, complete genomic sequences and mutational analyses of the Fukuyama-type congenital muscular dystrophy gene, fukutin. FEBS Letters, 489:192-196, 2001
  75. A. Hirano, M. Emi, M. Tsuneizumi, Y. Ueda, M. Yoshimoto, F. Kasumi, F. Akiyama, G. Sakamoto, S. Haga, T. Kajiwara, and Y. Nakamura: Allelic losses of loci at 3p25.1, 8p22, 13q12, 17p13.3 and 22q13 correlate with postoperative recurrence in breast cancer. Clinical Cancer Research, 7:876-882, 2001
  76. Y. Nakamura: Isolation of disease-associated genes through genome analysis and their clinical application. The Keio Journal of Medicine, 50134-140, 2001
  77. A. Iida, S. Saito, A. Sekine, T. Kitamoto, Y. Kitamura, C. Mishima, S. Osawa, K. Kondo, S. Harigae, and Y. Nakamura: Catalog of 434 single-nucleotide polymorphisms (SNPs) in genes of the alcohol dehydrogenase, glutathione S-transferase, and nicotinamide ademine dinucleotide, reduced (NADH) ubiquinone oxidoreductase families. Journal of Human Genetics, 46:385-407, 2001
  78. H. Ishiguro, T. Tsunoda, T. Tanaka, Y. Fujii, Y. Nakamura, and Y. Furukawa: Identification of AXUD1, a novel human gene induced by AXIN1 and its reduced expression in human carcinomas of the lung, liver, colon and kidney. Oncogene, 20:5062-5066, 2001
  79. M. Unoki, and Y. Nakamura: Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway. Oncogene, 20:4457-4465, 2001
  80. C. Kihara, T. Tsunoda, T. Tanaka, H. Yamana, Y. Furukawa, K. Ono, O. Kitahara, H. Zenbutsu, R. Yanagawa, K. Hirata, T. Takagi, and Y. Nakamura: Prediction of sensitivity of esophageal tumors to adjuvant chemotherapy by cDNA microarray analysis of gene-expression profiles. Cancer Research, 61:6474-6479, 2001
  81. Y. Furukawa, T. Kawasoe, Y. Daigo, T. Nishiwaki, H. Ishiguro, M. Takahashi, J. Kitayama, and Y. Nakamura: Isolation of a novel human gene, ARHGAP9, encoding a Rho-GTPase activating protein. Biochem. Biophy. Research Comm., 284:643-649, 2001
  82. Y.-M. Lin, K. Ono, S. Satoh, H. Ishiguro, M. Fujita, N. Miwa, T. Tanaka, T. Tsunoda, Y. Nakamura, and Y. Furukawa: Identification of AF17 as a downstream gene of the β-catenin/T-cell factor pathway and its involvement in colorectal carcinogenesis. Cancer Research, 61:6345-6349, 2001
  83. M. Furuhashi, K. Yagi, H. Yamamoto, Y. Furukawa, S. Shimada, Y. Nakamura, A. Kikuchi, K. Miyazono, and M. Kato: Axin facilitates Smad3 activation in the transforming growth factor-β signaling pathway. Molecular and Cellular Biology, 21:5132-5141, 2001
  84. R. Yanagawa, Y. Furukawa, T. Tsunoda, O. Kitahara, K. Murata, O. Ishikawa, and Y. Nakamura: Genome-wide screening of genes showing altered expression in liver metastases of human colorectal cancers by cDNA microarray. Neoplasia, 3:395-401, 2001
  85. Y. Ohnishi, T. Tanaka, K. Ozaki, R. Yamada, H. Suzuki and Y. Nakamura: A high-throughput SNP typing system for genome-wide association studies. Journal of Human Genetics, 46:471-477, 2001
  86. H. Iwasa, M. Kurabayashi, R. Nagai, Y. Nakamura, T. Tanaka: Genetic variations in five genes involved in the excitement of cardiomyocytes. Journal of Human Genetics, 46:549-552, 2001
  87. S. Saito, A. Iida, A. Sekine, Y. Miura, T. Sakamoto, C. Ogawa, S. Kawauchi, S. Higuchi, and Y. Nakamura: Identification of 197 genetic variations in six human methyltransferase genes in the Japanese population. Journal of Human Genetics, 46:529-537, 2001
  88. S. Okamura, H. Arakawa, T. Tanaka, H. Nakanishi, C. C. Ng, Y. Taya, M. Monden, and Y. Nakamura: p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis. Molecular Cell, 8:85-94, 2001
  89. A. Iida, S. Saito, A. Sekine, Y. Kitamura, K. Kondo, C. Mishima, S. Osawa, S. Harigae, and Y. Nakamura: High-density single-nucleotide polymorphism (SNP) map of the 150-kb region corresponding to the human ATP-binding cassette transporter A1(ABCA1) gene. Journal of Human Genetics, 46:522-528, 2001
  90. M. Fujita, Y. Furukawa, T. Tsunoda, T. Tanaka, M. Ogawa and Y. Nakamura: Up-regulation of the ENC1 (ectodermal-neural cortex 1) gene, a downstream target of the β-catenin/T-cell factor complex, in colorectal carcinomas. Cancer Research, 61:7722-7726, 2001
  91. Y. Suzuki, H. Taira, T. Tsunoda, J. Mizushima-Sugano, J. Sese, H. Hata, T. Ota, T. Isogai, T. Tanaka, S. Morishita, K. Okubo, Y. Sakaki, Y. Nakamura, A. Suyama, and S. Sugano: Diverse transcriptional initiation revealed by fine, large-scale mapping of mRNA start sites. EMBO reports, 2:388-393, 2001
  92. S. Okuno, T. K. Watanabe, T. Ono, K. Oga, A. Mizoguchi-Miyakita, Y. Yamasaki, Y. Goto, H. Shinomiya, H. Momota, H. Miyano, I. Hayashi, T. Asai, M. Suzuki, Y. Harada, H. Hishigaki, S. Wakitani, T. Takagi, Y. Nakamura, and A. Tanigami: Dffects of Dmo1 on obesity, dyslipiaemia and hyperglycemia in the Otsuka Long Evans Tokushima Fatty strain. Genet. Res., 77:183-190, 2001
  93. Y. Suzuki, T. Tsunoda, J. Sese, H. Taira, J. Mizushima-Sugano, H. Hata, T. ota, T. Isogai, T. tanaka, Y. Nakamura, A. Suyama, Y. Sakaki, S. Morishita, K. Okubo, and S. Sugano: Identification and characterization of the potential promoter regions of 1031 kinds of human genes. Genome Research, 11:677-684, 2001
  94. K. Yasui, I. Imoto, Y. Fukuda, A. Pimkhaokham, Z.Q. Yang, T. Naruto, Y. Shimada, Y. Nakamura, J. Inazawa: Identification of target genes within an amplicon at 14q12-q13 in esophageal squamous cell carcinoma. Genes Chromosomes and Cancer, 32:112-118, 2001
  95. C. Sakakura, A. Hagiwara, R. Yasuoka, Y. Fujita, M. Nakanishi, K. Masuda, K. Shimomura, Y. Nakamura, J. Inazawa, T. Abe, H. Yamagishi: Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation. British Journal of Cancer, 84:824-831, 2001
  96. A. Iida, S. Saito, A. Sekine, S. Harigae, S. Osawa, C. Mishima, K. Kondo, Y. Kitamura, and Y. Nakamura: Catalog of 46 single nucleotide polymorphisms (SNPs) in the microsomal glutathione S-transferase 1 (MGST1) gene. Journal of Human Genetics, 46:590-594, 2001
  97. A. Iida, Y. Ohnishi, K. Ozaki, Y. Ariji, A. Inose, M. Takahashi, Y. Nakamura, and T. Tanaka: High-density single-nucleotide polymorphism (SNP) map in the 96-kb region containing the entire human DiGeorge syndrome critical region 2 (DGCR2) gene at 22q11.2. Journal of Human Genetics, 46:604-608, 2001
  98. Y. Yamanaka, M. Tamar, T. Nakahata and Y. Nakamura: Gene-expression profiles of human small airway epithelial cells treated with low doses of 14- and 16-membered macrolides. Biochem. Biophy. Research Comm., 287:198-203, 2001
  99. A. Iida, S. Saito, A. Sekine, C. Mishima, K. Kondo, Y. Kitamura, S. Harigae, S. Osawa, and Y. Nakamura: Catalog of 258 single nucleotide polymorphisms (SNPs) in genes encoding three organic anion transporters, three organic anion-transporting polypeptides, and three NADH:ubiquinone oxidoreductase flavoproteins. Journal of Human Genetics, 46:668-683, 2001
  100. M. Murata, Y. Miyoshi, M. Ohshima, K. Shibata, T. Ohta, Y. Imai, M. Nishikawa, K. Iwao, H. Tateishi, T. Shimano, T. Kobayashi, and Y. Nakamura: Accumulation of β-catenin in the cytoplasm and the nuclei during the early hepatic tumorigenesis. Hepatology Research, 21:126-135, 2001
  101. M. Murata, Y. Miyoshi, K. Iwao, H. Wada, K. Shibata, H. Tateishi, T. Shimano, M. Ohsawa, Y. Imai, M. Nishikawa, T. Kobayashi, and Y. Nakamura: Combined hepatocellular/cholangiocellular carcinoma with sarcomatoid features: genetic analysis for histogenesis. Hepatology Research, 21:220-227, 2001
  102. N. Miwa, M. Furuse, S. Tsukita, N. Niikawa, Y. Nakamura and Y. Furukawa: Involvement of Claudin-1 in the β-catenin /Tcf signaling pathway and its frequent up-regulation in human colorectal cancers. Oncology Research, 12:469-476, 2001
  103. T. Yamaguchi, K. Matsuda, Y. Sagiya, M. Iwadate, M. A. Fujino, Y. Nakamura, and H. Arakawa: p53R2-dependent pathway for DNA synthesis in a p53-regulated cell-cycle checkpoint. Cancer Research, 61:8256-8262, 2001
  104. S. Haga, M. Emi, A. Hirano, Y. Utada, T. Kajiwara, F. Akiyama, G. Sakamoto, K. Takahashi, T. Tada, F. Kasumi, and Y. Nakamura: Association of allelic losses at 3p25.1, 13q12 or 17p13.3 woth poor prognosis in breast cancers with lymph node metastasis. Jpn. J. Cancer Research, 92:1199-1206, 2001
  105. M. Tsuneizumi, M. Emi, H. Nagai, H. Harada, G. Sakamoto, F. Kasumi,S. Inoue, T. Kazui and Y. Nakamura: Overexpression of the EBAG9 gene at 8q23 associated with early-stage breast cancer. Clinical Cancer Research, 7:3526-3532, 2001
  106. O. Guittet, P. Haansson, N. Voevodskaya, S. Fridd, A. Gralund, H. Arakawa, Y. Nakamura, and L. Thelander: Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells. Journal of Biological Chemistry, 276:40647-40651, 2001
  107. S. Iwashita, K. Koyama, and Y. Nakamura: VNTR sequence on human chromosome 11p15 that affects transcriptional activity. Journal of Human Genetics, 46:717-721, 2001
  108. H. Nakagawa, R.-B.Chadwick, P. Peltomaki, C. Plass, Y. Nakamura, A. de la Chapelle: Loss of imprinting of the insulin-like growth factor ・ gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer. Proc. Natl. Acad. Sci. USA, 98:591-596, 2001
  109. Y. Koshizuka, S. Ikegawa, M. Sano, K. Nakamura, and Y. Nakamura: Isolation of novel mouse genes associated with ectopic osscification by differential display method using ttw, a mouse model for ectopic ossification. Cytogenetics Cell Genetics, 94:163-168, 2001
  110. Y. Koshizuka, S. Ikegawa, M. Sano, K. Nakamura, Y. Nakamura: Isolation, characterization, and mapping of the mouse and human WDR8 genes, members of a novel WD-repeat gene family. Genomics, 72:252-259, 2001

    2002　　↑ページトップへ

  111. T. Mori, Y. Anazawa, M. Iiizumi, S. Fukuda, Y. Nakamura, and H. Arakawa: Identification of the interferon regulatory factor 5gene (IRF-5) as a direct target for p53. Oncogene, 21:2914-2918, 2002
  112. K. Ochi, T. Mori, Y. Toyama, Y. Nakamura and H. Arakawa: Identification of semaphorin3B as a direct target of p53. Neoplasia, 4:82-87, 2002
  113. K. Matsuda, K. Yoshida, Y. Taya, K. Nakamura, Y. Nakamura, H. Arakawa: p53AIP1 regulates the mitochondrial apoptotic pathway. Cancer Research, 62:2883-2889, 2002
  114. M. Iiizumi, H. Arakawa, .T Mori, A. Ando, and Y. Nakamura: Isolation of a novel gene, CABC1, encoding a mitochondrial protein that is highly homologous to yeast activity of bc1 complex. Cancer Research, 62:1246-1250, 2002
  115. A. Iida, S. Saito, A. Sekine, K. Kondo, C. Mishima, Y. Kitamura, S. Harigae, S. Osawa, and Y. Nakamura: Thirteen single nucleotide polymorphisms (SNPs) in the alcohol dehydrogenase 4 (ADH4) gene locus. Journal of Human Genetics, 47:74-76, 2002
  116. S. Dan, T. Tsunoda, O. Kitahara, R. Yanagawa, H. Zembutsu, T. Katagiri, K. Yamazaki, Y. Nakamura, and T. Yamori: An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines. Cancer Research, 62:1139-1147, 2002
  117. A. Iida, S. Saito, A. Sekine, C. Mishima, Y. Kitamura, K. Kondo, S. Harigae, S. Osawa, and Y. Nakamura: Catalog of 77 single nucleotide polymorphisms (SNPs) in the carbohydrate sulfotransferase 1 (CHST1) and carbohydrate sulfotransferase 3 (CHST3) genes. Journal of Human Genetics, 47:14-19, 2002
  118. H. Zembutsu, Y. Ohnishi, T. Tsunoda, Y. Furukawa, T. Katagiri, Y. Ueyama, N. Tamaoki, T. Nomura, O. Kitahara, R. Yanagawa, K. Hirata, and Y. Nakamura: Genome-wide cDNA microarray screening to correlate gene-expression profiles with sensitivity of 85 human-cancer xenografts to anticancer drugs. Cancer Research, 62:518-527, 2002
  119. M. Hirakawa, T. Tanaka, Y. Hashimoto, M. Kuroda, T. Takagi, and Y. Nakamura: JSNP: a database of common gene variations in the Japanese population. Nucleic Acids Research, 30:158-162, 2002
  120. S. Saito, A. Iida, A. Sekine, Y. Miura, C. Ogawa, S. Kawauchi, S. Higuchi, and Y. Nakamura: 326 genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population. Journal of Human Genetics, 47:38-50, 2002
  121. T. Takei, A. Iida, K. Nitta, T. Tanaka, Y. Ohnishi, R. Yamada, S. Maeda, T. Tsunoda, S. Takeoka, K. It o, K. Honda, K. Uchida, K. Tsuchiya, Y. Suzuki, T. Fujioka, T. Ujiie, Y. Nagane, S. Miyano, I. Narita, F. Gejyo, H. Nihei, Y. Nakamura: Association between single-nucleotide polymorphisms in selectin genes and IgA nephropathy. Am. J. Human Genetics, 70:781-786, 2002
  122. M. Doi, A. Nagano and Y. Nakamura: Genome-wide screening by cDNA microarray of genes associated with matrix mineralization by human mesenchymal stem cells in vitro. Biochem. Biophy. Research Comm., 290:381-390, 2002
  123. H. Yamanaka, N. Hashimoto, K. Koyama, H. Nakagawa, Y. Nakamura, and K. Noguchi: Expression of Apc2 during mouse development. Gene Expression Patterns, 1:107-114, 2002
  124. M. Tsuneizumi, M. Emi, A. Hirano, Y. Utada, K. Tsumagari, K. Takahashi, F. Kasumi, F. Akiyama, G. Sakamoto, T. Kazui and Y. Nakamura: Assocaition of allelic loss at 8p22 with poor prognosis amang breast cancer cases treated with high-dose adjuvant chemotherapy. Cancer Letters, 180:75-82, 2002
  125. M. Tachikawa, Y. Nagai, K .Nakamura, K. Kobayashi, T. Fujiwara, H-J. Han, Y. Nakabayashi, Y. Ichikawa, J. Goto, I. Kanazawa, Y. Nakamura, and T. Toda: Identification of CAG repeat-containing genes expressedin human brain as candidate genes for autosomal dominant spinocerebellar ataxias and other neurodegenerative diseases. Journal of Human Genetics, 47:275-278, 2002
  126. T. Nagahata, A. Hirano, Y. Utada, S. Tsuchiya, K. Takahashi, T. Tada, M. Makita, F. Kasumi, F. Akiyama, G. Sakamoto, Y. Nakamura, and M. Emi: Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers. Breast Cancer, 9:208-215, 2002
  127. D.G. Duda, M. Sunamura, L. Lozonshi, T. Yokoyama, T. Yatsuoka, A. Horii, K. Tani, S. Asano, Y. Nakamura, and S. Matsuno: Overexpression of the p53-inducible brain-specific angiogenesis inhibitor 1 suppresses efficiently tumour angiogenesis. British Journal of Cancer, 86:490-496, 2002
  128. Y. Sasaki, S. Ishida, I. Morimoto, T. Yamashita, T. Kojima, C. Kihara, T. Tanaka, K. Imai, Y. Nakamura, and T. Tokino: The p53 family member genes are involved in the notch signal pathway. Journal of Biological Chemistry, 277:719-724, 2002
  129. M. Iizaka, Y. Furukawa, T. Tsunoda, H. Akashi, M. Ogawa, and Y. Nakamura: Expression profile analysis of colon cancer cells in response to sulindac or aspirin. Biochem. Biophy. Research Comm., 292:498-512, 2002
  130. K. Miura, E. D. Bowman, R. Simon, A. C. Peng, A. I. Robles, R. T. Jones, T. Katagiri, P. He, H. Mizukami, L. Charboneau, T. Kikuchi, L. A. Liotta, Y. Nakamura, and C. C. Harris: Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles. Cancer Research, 62:3244-3250, 2002
  131. J. Kamogawa, M.Terada, S. Mizuki, M, Nishihara, H. Yamamoto, S, Mori, Y. Abe, K. Morimoto, S. Nakatsuru, Y. Nakamura, and M. Nose: Arthritis in MRL/lpr Mice Is Under the Control of MultipleGene Loci With an Allelic Combination Derived From the Original InbredStrains. Arthritis & Rheumatism, 46:1067-1074, 2002
  132. T. Mori, Y. Anazawa, K. Matsui, S. Fukuda, Y. Nakamura, and H. Arakawa: Cyclin K as a direct transcriptional target of the p53 tumor suppressor. Neoplasia, 4:268-274, 2002
  133. S. Saito, A. Iida, A. Sekine, Y. Miura, C. Ogawa, S. Kawauchi, S. Higuchi, and Y. Nakamura: Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR). Journal of Human Genetics, 47:147-171, 2002
  134. S. Higuchi, Y. Nakamura and S. Saito: Characterization of a VNTR polymorphism in the coding region of the CEL gene. Journal of Human Genetics, 47:213-215, 2002
  135. Y.-M. Lin, Y. Furukawa, T. Tsunoda, C.-T. Yue, K.-C. Yang, and Y. Nakamura: Molecular diagnosis of colorectal tumors by expression profiles of 50 genes expressed differentially in adenomas and carcinomas. Oncogene, 21:4120-4128, 2002
  136. H. Iwasa, T. Itoh, R. Nagai, Y. Nakamura, T. Tanaka: Twenty single-nucleotide polymorphisms in four genes encording cardiac ion channels. Journal of Human Genetics, 47:208-212, 2002
  137. T. Kayashima, M. Katahira, N. Harada, N. Miwa, T. Ohta, K. Yoshiura, N. Matsumoto, Y. Nakane, Y. Nakamura, T. Kajii, N. Niikawa, and T. Kishino: Maternal Isodisomy for 14q21-24 in a man with daiabetes mellitus. American journal of Medical Genetics, 111:38-42, 2002
  138. M. Nishiu, R. Yanagawa,S. Nakatsuka, M. Yao, T. Tsunoda, Y. Nakamura, and K. Aozasa: Microarray analysis of gene-expression profiles in diffuse large B-cell lymphoma: Identification of genes related to disease progression. Jpn. J. Cancer Research, 93:894-901, 2002
  139. A. Iida, S. Saito, A. Sekine, C. Mishima, Y. Kitamura, K. Kondo, S. Harigae, S. Osawa, and Y. Nakamura: Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8. Journal of Human Genetics, 47:285-310, 2002
  140. O. Kitahara, T. Katagiri, T. Tsunoda, Y. Harima, and Y. Nakamura: Classification of sensitivity or resistance of cervical cancers to ionizing radiation according to expression profiles of 62 genes selected by cDNA microarray analysis. Neoplasia, 4:295-303, 2002
  141. R. Yagyu, R. Hamamoto, Y. Furukawa, H. Okabe, T. Yamamura, and Y. Nakamura: Isolation and characterization of a novel human gene, VANGL1, as a therapeutic target for hepatocellular carcinoma. International Journal of Oncology, 20:1173-1178, 2002
  142. A. Saito-Hisaminato, T. Katagiri, S. Kakiuchi, T. Nakamura, T. Tsunoda, and Y. Nakamura: Genome-wide profiling of gene expression in 29 normal human tissues with a cDNA microarray. DNA Research, 9:35-45, 2002
  143. F. Saito-Ohara, Y. Fukuda, M. Ito, K.L. Agarwala, M. Hayashi, M. Matsuo, I. Imoto, K. Yamakawa, Y. Nakamura, and J. Inazawa: The Xq22 inversion breakpoint interrupted a novl ras-like GTPase gene in a patient with Duchenne muscular dystrophy and profound mental reterdation. Am. J. Human Genetics, 71:637-645, 2002
  144. S. Nagayama, T. Katagiri, T. Tsunoda, T. Hosaka, Y. Nakashima, N. Araki, K. Kusuzaki, T. Nakayama, T. Tsuboyama, T. Nakamura, M. Imamura, Y. Nakamura, and J. Toguchida: Genome-wide analysis of gene expression in synovial sarcomas using a cDNA microarray. Cancer Research, 62:5859-5866, 2002
  145. M. Takahashi, T. Tsunoda, M. Seiki, Y. Nakamura, and Y. Furukawa: Identification of membrane-type matrix metalloproteinase-1 as a target of the β-catenin/Tcf4 complex in human colorectal cancers. Oncogene, 21:5861-5867, 2002
  146. S. Saito, A. Iida, A. Sekine, C. Ogawa, S. Kawauchi, S. Higuchi, M. Ohno, and Y. Nakamura: 906 variations among 27 genes encoding cytochrome P450 (CYP) enzymes and aldehyde dehydrogenases (ALDH) in the Japanese population. Journal of Human Genetics, 47:419-444, 2002
  147. K. Inoue, K. Matsuda, M. Itoh, H. Tomoike, T. Aoyagi, R. Nagai, M. Hori, Y. Nakamura, and T. Tanaka: Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5. Human Molecular Genetics, 11:1775-1784, 2002
  148. H. Ishiguro, T. Shimokawa, T. Tsunoda, T. Tanaka, Y. Fujii, Y. Nakamura and Y. Furukawa: Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas. Oncogene, 21:6387-6394, 2002
  149. K. Yamazaki, M. Takazoe, T. Tanaka, T. Ichimori, and Y. Nakamura: Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's Disease. Journal of Human Genetics, 47:469-472, 2002
  150. A. Iida, S. Saito, A. Sekine, C. Mishima, Y. Kitamura, K. Kondo, S. Harigae, S. Osawa, and Y. Nakamura: Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8. Journal of Human Genetics, 47:505-510, 2002
  151. F. Akiyama, T. Tanaka, R. Yamada, Y. Ohnishi, T. Tsunoda, S. Maeda, T. Takei, W. Obara, K. Ito, K. Honda, K. Uchida, K. Tsuchiya, K. Nitta, K. Yumura, H. Nihei, T. Ujiie, Y. Nagane, Y. Suzuki, T. Fujioka, I. Narita, F. Gejyo, and Y. Nakamura: Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy. Journal of Human Genetics, 47:532-538, 2002
  152. S. Saito, A. Iida, A. Sekine, C. Ogawa, S. Kawauchi, S. Higuchi, and Y. Nakamura: Catalog of 238 variations among six human genes encoding solute carriers (hSLCs) in the Japanese population. Journal of Human Genetics, 47:576-584, 2002
  153. M. Takahashi, M. Fujita, Y. Furukawa, R. Hamamoto, T. Shimokawa, N. Miwa, and Y. Nakamura: Isolation of a novel human gene, APCDD1, as a direct target of the β-catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis. Cancer Research, 62:5651-5656, 2002
  154. Y. Yamanaka, Y. Hamazaki, Y. Sato, K. Ito, K. Watanabe, T. Heike, T. Nakahata and Y. Nakamura: Maturational sequence of neuroblastoma revealed by molecular analysis on cDNA microarrays. International Journal of Oncology, 21:803-807, 2002
  155. Y. Kaneta, Y. Kagami, T. Katagiri, T. Tsunoda, I. Jin-nai, H. Taguchi, H. Hirai, K. Ohnishi, T. Ueda, N. Emi, A. Tomida, T. Tsuruo, Y. Nakamura, and R. Ohno: Prediction of sensitivity to STI571 among chronic myeloid leukemia patients by genome-wide cDNA microarray analysis. Jpn. J. Cancer Research, 93:849-856, 2002
  156. H. Haga, R. Yamada, Y. Ohnishi, Y. Nakamura, and T. Tanaka: Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190,562 genetic variations in the human genome. Journal of Human Genetics, 47:605-610, 2002
  157. M. Horie, K. Kobayashi, S. Takeda, Y. Nakamura, G. E. Lyons, and T. Toda: Isolation and characterization of the mouse ortholog of the Fukuyama-type congenital musclular dystrophy gene. Genomics, 80:482-486, 2002
  158. S. Hasegawa, Y. Furukawa, M. Li, S. Satoh, T. Kato, T. Watanabe, T. Katagiri, T. Tsunoda, Y. Yamaoka, and Y. Nakamura: Genome-wide analysis of gene expression in intestinal-type gastric cancers using a cDNA microarray representing 23,040 genes. Cancer Research, 62:7012-7017, 2002
  159. K. Ozaki, Y. Ohnishi, A. Iida, A. Sekine, R. Yamada, T. Tsunoda, H. Sato, H. Sato, M. Hori, Y. Nakamura, and T. Tanaka: Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction. Nature Genetics, 32:650-654, 2002
  160. J. Okutsu, T. Tsunoda, Y. Kaneta, T. Katagiri, O. Kitahara, H. Zembutsu, R. Yanagawa, S. Miyawaki, K. Kuriyama, N. Kubota, Y. Kimura, K. Kubo, F. Yagasaki, T. Higa, H.Taguchi, T. Tobita, H. Akiyama, A. Takeshita, Y.-H. Wang, T. Motoji, R. Ohno, and Y. Nakamura: Prediction of chemosensitivity for patients with acute myeloid leukemia, according to expression levels of 28 genes selected by genome-wide cDNA microarray analysis. Molecular Cancer Therapeutics, 1:1035-1042, 2002
  161. S. Rokudai, N. Fujita, O. Kitahara, Y. Nakamura, and T. Tsuruo: Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis. Molecular and Cellular Biology, 22:8695-8708, 2002
  162. H. Nishimori, Y. Sasaki, K. Yoshida, H. Irifune, H. Zenbutsu, T. Tanaka, T. Aoyama, T. Hosaka, S. Kawaguchi, T. Wada, J. Hata, J. Toguchida, Y. Nakamura, and T. Tokino: The Id2 gene is a novel target of the transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors. Oncogene, 21:8302-8309, 2002
  163. S.Okuno, M. Kondo, Y. Yamasaki, H. Miyano, T. Ono, T. Iwanaga, K. Omori, M. Okano, M. Suzuki, H. Momota, H. Hishigaki, I. Hayashi, Y. Goto, H. Shinomiya, Y. Harada, T. Hirashima, N. Kanemoto, T. Asai, S. Wakitani, T. Takagi, Y. Nakamura, A. Tanigami, and K. Watanabe: Substitution of Dmo1 with normal alleles results in decreased manifestation of diabetes in OLETF rats. Diabetes, Obesity, and Metabolism, 4:309-318, 2002

    2003　　↑ページトップへ

  164. S. Abe, T. Katagiri, A. Saito-Hisaminato, S. Usami, Y. Inoue, T. Tsunoda, and Y. Nakamura: Identification of CRYM as a candidate responsible for non-syndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues. Am. J. Human Genetics, 72:73-82, 2003
  165. S. Tsukada, M. Iwai, J. Nishiu, M. Itoh, H. Tomoike, M. Horiuchi, Y. Nakamura, and T. Tanaka: Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor. Circulation, 313-319, 2003
  166. S. Abe, K. Koyama, S. Usami, Y. Nakamura: Construction and characterization of a vestibular-specific cDNA library using T7-based RNA amplification. Journal of Human Genetics, 48:142-149, 2003
  167. A. Iida, T. Tanaka, and Y. Nakamura: High-density SNP map of human ITR, a gene associated with vascular remodeling. Journal of Human Genetics, 48:170-172, 2003
  168. A. Iida, and Y. Nakamura: High-resolution SNP map in the 55-kb region containing the selectin gene family on chromosome 1q24-q25. Journal of Human Genetics, 48:150-154, 2003
  169. T. Kikuchi, Y. Daigo, T. Katagiri, T. Tsunoda, K. Okada, S. Kakiuchi, H. Zembutsu, Y. Furukawa, M. Kawamura, K. Kobayashi, K. Imai, and Y. Nakamura: Expression profiles of non-small cell lung cancers on cDNA microarrays: Identification of genes for prediction of lymph node metastasis and sensitivity to anti-cancer drugs. Oncogene, 22:2192-2205, 2003
  170. T. Arimoto, T. Katagiri, K. Oda, T. Tsunoda, T. Yasugi, Y. Osuga, H. Yoshikawa, O. Nishii, T. Yano, Y. Taketani and Y. Nakamura: Genome-wide cDNA microarray analysis of gene-expression profiles involved in ovarian endometriosis. International Journal of Oncology, 22:551-560, 2003
  171. A. Iida, S. Saito, A. Sekine, C. Mishima, Y. Kitamura, K. Kondo, S. Harigae, S. Osawa, and Y. Nakamura: Catalog of 668 SNPs detected among 31 genes encoding potential drug targets on the cell surface. Journal of Human Genetics, 48:23-46, 2003
  172. M. Unoki, and Y. Nakamura: EGR2 induces apoptosis in various cancer-cell lines by direct transactivation of BNIP3L and BAK. Oncogene, 22:2172-2185, 2003
  173. K. Ochi, A. Saito-Hisaminato, Y. Daigo, T. Katagiri, Y. Toyama, H. Matsumoto and Y. Nakamura: Expression profiles of two types of human knee-joint cartilage. Journal of Human Genetics, 48:177-182, 2003
  174. C. Tanikawa, K. Matsuda, S. Fukuda, Y. Nakamura, and H. Arakawa: p53RDL regulates p53-dependent apoptosis. Nature Cell Biology, 5:216-223, 2003
  175. G. Watanabe, H. Nishimori, H. Irifune, Y. Sasaki, S. Ishida, H. Zenbutsu, T. tanaka, S. Kawaguchi, T. Wada, J. hata, M. Kusakabe, K. Yoshida, Y. Nakamura, and T. Tokino: Induction of Tenascin-C by tumor-specific EWS-ETS fusion genes. Genes Chromosomes and Cancer, 36:224-232, 2003
  176. M. Unoki, J. Okutsu, and Y. Nakamura: Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia. International Journal of Oncology, 22:1217-1223, 2003
  177. A. Yamada, T. Miyazaki,L-M. Lu, M. Ono, M. T. Ito, M. Terada, S. Mori, K. Hata, Y. Nozaki, S. Nakatsuru, Y. Nakamura, M. Onji, and M. Nose: Genetic basis of tissue specificity of vasculitis in MRL/lpr mics. Arthritis & Rheumatism, 48:1445-1451, 2003
  178. S. Saito, A. Iida, A. Sekine, S. Kawagichi, S. Higuchi, C. Ogawa, and Y. Nakamura: Catalog of 680 variations among 8 cytochrome P450 (CYP) genes, nine esterase genes, and two other genes in the Japanese population. Journal of Human Genetics, 48:249-270, 2003
  179. R. Ohno, and Y. Nakamura: Prediction of response to Imatinib by cDNA microarray analysis. Seminors in Hematology, 40:42-49, 2003
  180. S. Kakiuchi, Y. Daigo, T. Tsunoda, S. Yano, S. Sone, and Y. Nakamura: Genome-wide analysis of organ-preferential metastasis of human small cell lung cancer in mice. Molecular Cancer Research, 1:485-499, 2003
  181. H. Zembutsu, Y. Ohnishi, Y. Daigo, T. Katagiri, T. Kikuchi, S. Kakiuchi, K. Hirata and Y. Nakamura: Gene-Expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839. International Journal of Oncology, 23:29-39, 2003
  182. W. Obara, A. Iida, Y. Suzuki, T. Tanaka, F. Akiyama, S Maeda, Y Ohnishi, R. Yamada, A. Sekine, T. Tsunoda, T. Takei, K. Ito, K. Honda, K. Uchida, K. Tsuchiya, W. Yumura, T. Ujiie, Y. Nagane, K. Nitta, S. Miyano, I. Narita, F. Gejyo, H. Nihei, T. Fujioka, and Y. Nakamura: Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with Immunoglobulin A nephropathy (IgAN) in Japanese patients. Journal of Human Genetics, 48:293-299, 2003
  183. H. Okabe, S. Satoh, Y. Furukawa, T. Kato, S. Hasegawa, Y. Nakajima, Y. Yamaoka, and Y. Nakamura: Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1. Cancer Research, 63:3043-3048, 2003
  184. S. Takeda, M. Kondo, J.Sasaki, H. Kurahashi, H. Kano, K. Arai, K. Misaki, T. Fukui, K. Kobayashi, M. Tachikawa, M. Imamura, Y. Nakamura, T. Shimizu, T. Murakami, Y. Sunada. T. Fujikado, K. Matsumura, T. Terashima and T. Toda: Fukutin is required for maintenance of muscle integrity, cortical histiogenesis and normal eye development. Human Molecular Genetics, 12:1449-1459, 2003
  185. C.-C. Ng, H. Arakawa, S. Fukuda, H. Kondoh, and Y. Nakamura: p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1. Oncogene, 22:4449-4458, 2003
  186. T. Kimura, M. Gotoh, Y. Nakamura and H. Arakawa: hCDC4b, a regulator of Cyclin E, as a direct transcriptional target of p53. Cancer Science, 94:431-436, 2003
  187. Y. Kaneta, Y. Kagami, T. Tsunoda, R. Ohno, Y. Nakamura, and T. Katagiri: Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray. International Journal of Oncology, 23:681-691, 2003
  188. A. Iida, and Y. Nakamura: Japanese Efforts in Pharmacogenomics. Current Pharmacogenomics, 1:203-215, 2003
  189. K. Okada, T. Katagiri, T. Tsunoda, Y. Mizutani, Y. Suzuki, M. Kamada, T. Fujioka, T. Shuin, T. Miki, and Y. Nakamura: Analysis of gene-expression profiles in testicular seminomas using a genome-wide cDNA microarray. International Journal of Oncology, 23:1615-1635, 2003
  190. K. Ueda, H. Arakawa and Y. Nakamura: Dual-Specificity Phosphatase 5 (DUSP5) as a direct　transcriptional target of tumor suppressor p53. Oncogene, 22:5586-5591, 2003
  191. T. Nakatsura, Y. Yoshitake, S. Senju, M. Monji, H. Komori, Y. Motomura, S. Hosaka, T. Beppu, T. Ishiko, H. Kamohara, H. Ashihara, T. Katagiri, Y. Furukawa, S. Fujiyama, M. Ogawa, Y. Nakamura, and Y. Nishimura: Glypican-3, over-expressed specifically in human hepatocellular carcinoma, is a novel tumor marker. Biochem. Biophy. Research Comm., 306:16-25, 2003
  192. A. Iida, K. Ozaki, Y. Ohnishi, T. Tanaka and Y. Nakamura: Identification of 46 novel SNPs in the 130-kb region containing a myocardial infarction susceptibility gene on chromosomal band 6p21. Journal of Human Genetics, 48:476-479, 2003
  193. T. Shimokawa, Y. Furukawa, M. Sakai, M. Li, N. Miwa, Y.-M. Lin and Y. Nakamura: Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the β-catenin/T-cell factor complex. Cancer Research, 63:6116-6120, 2003
  194. A. Suzuki, R. Yamada, X. Chang, S.Tokuhiro, T. Sawada, M. Suzuki, M. Nagasaki, M. Nakayama-Hamada, R.Kawaida, M. Ono, M. Ohtsuki, H. Furukawa, S. Yoshino, M. Yukioka, S. Touma, T. Matsubara, S. Wakitani, R. Teshima, A. Sekine, A.Iida, A. Takahashi, T. Tsunoda, Y. Nakamura, and K. Yamamoto: Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis. Nature Genetics, 34:395-402, 2003
  195. T. Kimura, S. Takeda, Y. Sagiya, M. Gotoh, Y. Nakamura and H. Arakawa: Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools. Nature Genetics, 34:440-445, 2003
  196. S. Saito, A. Iida, A. Sekine, S. Kawauchi, S. Higuchi, C. Ogawa, and Y. Nakamura: Catalog of 178 variations in the Japanese population among eight human genes encoding G protein-coupled receptors (GPCRs). Journal of Human Genetics, 48:461-468, 2003
  197. N. Tanaka, T. Babazono, S. Saito, A. Sekine, T. Tsunoda, M. Haneda, Y. Tanaka, T. Fujioka, K. Kaku, R. Kawamori, R. Kikkawa, Y. Iwamoto, Y. Nakamura and S. Maeda: Associationof solute carrier family 12 (sodium/chloride) member 3 with diabetic nephropathy, identified by genome-wide analyses of Single Nucleotide Polymorphisms. Diabetes, 52:2848-2853, 2003
  198. C. Suzuki, Y. Daigo, T. Kikuchi, T. Katagiri and Y. Nakamura: Identification of COX17 as a therapeutic target for non-small cell lung cancer. Cancer Research, 63:7038-7041, 2003
  199. S. Abe, S. Usami, and Y. Nakamura: Mutations in the gene encoding KIAA1199 protein, an inner-ear protein expressed in Deiters' cells and the fibrocytes, as the cause of nonsyndromic hearing loss. Journal of Human Genetics, 48:564-570, 2003
  200. M. Unoki, and Y. Nakamura: Methylation at CpG islands in intron1 of EGR2 confers enhancer-like activity. FEBS letters, 554:67-72, 2003
  201. S. Tokuhiro, R. Yamada, X. Chang, A. Suzuki, Y. Kochi, T. Sawada, M. Suzuki, M. Nagasaki, M. Ohtsuki, M. Ono, H. Furukawa, M. Nagashima, S. Yoshino, A. Mabuchi, A. Sekine, S. Saito, A. Takahashi, T. Tsunoda, Y. Nakamura and K. Yamamoto: An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis. Nature Genetics, 35:341-348, 2003
  202. The International HapMap Consortium: The International HapMap Project. Nature, 426:789-796, 2003
  203. Y. Koshizuka, T. Yamada, K. Hoshi, T. Ogasawara, U. Chung, H. Kawano, Y. Nakamura, K. Nakamura, S. Ikegawa, H. Kawaguchi: Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway. Journal of Biological Chemistry, 278:48259-48266, 2003
  204. S. Dan, M. Shirakawa, Y. Mukai, Y. Yoshida, K. Yamazaki, T. Kawaguchi, M. Matsuura, Y. Nakamura, and T. Yamori: Identification of Candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines. Cancer Science, 94:1074-1082, 2003
  205. Y. Sasaki, H. Mita, M. Toyota, S. Ishida, I. Morimoto, T. Yamashita, T. Tanaka, K. Imai, Y. Nakamura, and T. Tokino: Identification of the interleukin 4 receptor α gene as a direct target for p73. Cancer Research, 63:8145-8152, 2003

    2004　　↑ページトップへ

  206. H. Okabe, Y. Furukawa, T. Kato, S. Hasegawa, Y. Yamaoka, and Y. Nakamura: Isolation of development and differentiation enhancing factor-like 1 (DDEFL1) as a drug target for hepatocellular carcinomas. International Journal of Oncology, 24:43-48, 2004
  207. Y. Anazawa, H. Arakawa,H. Nakagawa, and Y. Nakamura: Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway. Oncogene, 23:7621-7627, 2004
  208. K. Yoshida, M. Monden, Y. Nakamura and H. Arakawa: Adenovirus-mediated p53AIP1 gene transfer as a new strategy for treatment of p53-resistant tumors. Cancer Science, 95:91-97, 2004
  209. M. Li, Y.-M. Lin, S. Hasegawa, T. Shimokawa, K. Murata, M. Kameyama, O. Ishikawa, T. Katagiri, T. Tsunoda, Y. Nakamura and Y. Furukawa: Genes associated with liver metastasis of colon cancer, identified by genome-wide cDNA microarray. International Journal of Oncology, 24:305-312, 2004
  210. S. Nagayama, M. Iiizumi, T. Katagiri, J. Toguchida and Y. Nakamura: Identification of PDZK4, a novel human gene with PDZ domains, that is up-regulated in synovial sarcomas. Oncogene, 23:5551-5557, 2004
  211. K. Ochi, Y. Daigo, T. Katagiri, S. Nagayama, T. Tsunoda, A. Myoui, N. Naka, N. Araki, I. Kudawara, M. Ieguchi, Y. Toyama, J. Toguchida, H. Yoshikawa and Y. Nakamura: Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles. International Journal of Oncology, 24:647-655, 2004
  212. Y. Nakamura: Isolation of p53-target genes and their functional analysis (Review). Cancer Science, 95:7-11, 2004
  213. T. Sekiya, S. Adachi, K. Kohu, T. Yamada, O. Higuchi, Y. Furukawa, Y. Nakamura, T. Nakamura, K. Tashiro, S. Kuhara, S. Ohwada, and T. Akiyama: Identification of BAMBI, an inhibitor of TGF-β signaling, as a target of the β-catenin pathway in colorectal tumor cells. Journal of Biological Chemistry, 279:6840-6846, 2004
  214. M. Doi, A. Nagano, and Y. Nakamura: Molecular Cloning and Characterization of a Novel Gene, EMILIN-5, and Its Possible Involvement in Skeletal Development. Biochem. Biophy. Research Comm., 313:888-893, 2004
  215. K. Yoon, Y. Nakamura and H. Arakawa: p53 directly transactivates ALDH4 by various cellular stresses. Journal of Human Genetics, 49:134-140, 2004
  216. T. Nakamura, Y. Furukawa, T. Tsunoda, H. Ohigashi, K. Murata, O. Ishikawa, K. Ohgaki, N. Kashimura, M. Miyamoto, S. Hirano, S. Kondo, H. Katoh, and Y. Nakamura, and T. Katagiri: Genome-wide cDNA microarray analysis of gene-expression profiles in pancreatic cancers Using populations of tumor cells and normal ductal epithelial cells selected for purity by laser microdissection. Oncogene, 23:2385-2400, 2004
  217. T. Ota, Y. Suzuki, T. Nishikawa, T. Otsuki, T. Sugiyama, R. Irie, A. Wakamatsu, K. Hayashi, H. Sato, K. Nagai, K. Kimura, H. Makita, M. Sekine, M. Obayashi, T. Nishi, T. Shibahara, T. Tanaka, S. Ishii, J. Yamamoto, K. Saito, Y. Kawai, Y. Isono, Y. Nakamura, K. Nagahari, K. Murakami, T. Yasuda, T. Iwayanagi, M. Wagatsuma, A. Shiratori, H. Sudo, T. Hosoiri, Y. Kaku, H. Kodaira, H. Kondo, M. Sugawara, M. Takahashi, K. Kanda, T. Yokoi, T. Furuya, E. Kikkawa, Y. Omura, K. Abe, K. Kamihara, N. Katsuta, K. Sato, M. Tanikawa, M. Yamazaki, K. Ninomiya, T. Ishibashi, H. Yamashita, K. Murakawa, K. Fujimori, H. Tanai, M. Kimata, M. Watanabe, S. Hiraoka, Y. Chiba, S. Ishida, Y. Ono, S. Takiguchi, S. Watanabe, M. Yosida, T. Hotuta, J. Kusano, K. Kanehori, A. Takahashi-Fujii, H. Hara, T. Tanase, Y. Nomura, S. Togiya, F. Komai, R. Hara, K. Takeuchi, M. Arita, N. Imose, K. Musashino, H. Yuuki, A. Oshima, N. Sasaki, S. Aotsuka, Y. Yoshikawa, H. Matsunawa, T. Ichihara, N. Shiohata, S. Sano, S. Moriya, H. Momiyama, N. Satoh, S. Takami, Y. Terashima, O. Suzuki, S. Nakagawa, A. Senoh, H. Mizoguchi, Y. Goto, F. Shimizu, H. Wakebe, H. Hishigaki, T. Watanabe, A. Sugiyama, M. Takemoto, B. Kawakami, M. Yamazaki, K. Watanabe, A. Kumagai, S. Itakura, Y. Fukuzumi, Y. Fujimori, M. Komiyama, H. Tashiro, A. Tanigami, T. Fujiwara, T. Ono, K. Yamada, Y. Fujii, K. Ozaki, M. Hirao, Y. Ohmori, A. Kawabata, T. Hikiji, N. Kobatake, H. Inagaki, Y. Ikema, S. Okamoto, R. Okitani, T. Kawakami, S. Noguchi, T. Itoh, K. Shigeta, T. Senba, K. Matsumura, Y. Nakajima, T. Mizuno, M. Morinaga, M. Sasaki, T. Togashi, M. Oyama, H. Hata, M. Watanabe, T. Komatsu, J. Mizushima-Sugano, T. Satoh, Y. Shirai, Y. Takahashi, K. Nakagawa, K. Okumura, T. Nagase, N. Nomura, H. Kikuchi, Y. Masuho, R. Yamashita, K. Nakai, T. Yada, Y. Nakamura, O. Ohara, T. Isogai and S. Sugano: Complete sequencing and characterization of 21,243 full-length human cDNAs. Nature Genetics, 36:40-45, 2004
  218. A. Iida, S. Saito, A. Sekine, Y. Kataoka, W. Tabei, and Y. Nakamura: Catalog of 300 SNPs in 23 genes encoding G-protein coupled receptors. Journal of Human Genetics, 49:194-208, 2004
  219. Y. Kochi, R. Yamada, K. Kobayashi, A. Takahashi, A. Suzuki, A. Sekine, A. Mabuchi, F. Akiyama, T. Tsunoda, Y. Nakamura, and K. Yamamoto: Analysis of single-nucleotide polymorphisms in Japaneserheumatoid arthritis patients shows additional susceptibility markers besidesthe classic shared epitope susceptibility sequences. Arthritis & Rheumatism,50:63-71, 2004
  220. Y.Harima,A. Togashi, K. Horikoshi, M. Imamura, M. Sougawa, S. Sawada, T. Tsunoda, Y. Nakamura, and T. Katagiri:Prediction of outcome of advanced cervical cancer to thermoradiotherapy according to expression profiles of 35 genes selected by cDNA microarray analysis.Int. J. of Radiation Oncology, Biology, Physics,60:237-248,2004
  221. D. Yuki, Y.-M. Lin, Y. Fujii, Y. Nakamura, and Y. Furukawa: Isolation of LEMD domain containing 1, a novel testis-specific gene expressed in colorectal cancer. Oncology Report, 12:275-280, 2004
  222. N. Jinawath, Y. Furukawa, and Y. Nakamura: Identification of NOL8,a nucleolar protein containing an RNA recognition motif (RRM),which was overexpressed in diffuse-type gastric cancer. Cancer Science, 95:430-435, 2004
  223. A. Iida, Y. Nakamura: Identification of 45 novel SNPs in the 83-kb region containing peptidylarginine deiminase types 1 and 3 loci on chromosomal band 1p36.13. Journal of Human Genetics, 49:387-390, 2004
  224. K. Ozaki, K. Inoue, H. Sato, A. Iida, Y. Ohnishi, A. Sekine, H. Sato, K. Odashiro, M. Nobuyoshi, M. Hori, Y. Nakamura, and T. Tanaka: Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-α secretion in vitro. Nature, 429:72-75, 2004
  225. N. Kamatani, A. Sekine, T. Kitamoto, A. Iida, S. Saito, A. Kogame, E. Inoue, M. Kawamoto, M. Harigai, and Y. Nakamura: Large-scale single-nucleotide polymorphism (SNP) and haplotype analyses, using dense SNP maps, of 199 drug-related genes in 752 subjects: The analysis of the association between uncommon SNPs within haplotype blocks and the haplotypes constructed with haplotype-tagging SNPs. Am. J. Human Genetics, 75:190-203, 2004
  226. A. Iida, S. Saito, A. Sekine, W. Tabei, Y. Kataoka, and Y. Nakamura: Identification of 20 novel SNPs in the guanine nucleotide binding protein alpha 12 gene locus. Journal of Human Genetics, 49:445-448, 2004
  227. N. Jinawath, Y. Furukawa, S. Hasegawa, M. Li, T. Tsunoda, S. Satoh, T. Yamaguchi, H. Imamura, M. Inoue, H. Shiozaki, and Y. Nakamura: Comparison of gene-expression profiles between diffuse-and intestinal-type gastric cancers using a genome-wide cDNA microarray. Oncogene, 23:6830-6844, 2004
  228. T. Tsunoda, G. M. Lathrop, A. Sekine, R. Yamada, A. Takahashi, Y. Ohnishi, T. Tanaka and Y. Nakamura: Variation of gene-based SNPs and linkage disequilibrium patterns in the human genome. Human Molecular Genetics, 13:1623-1632, 2004
  229. R. Hamamoto, Y. Furukawa, M. Morita, Y. Iimura, F. P. Silva, M. Li, R. Yagyu and Y. Nakamura: SMYD3 encodes a novel histone methyltransferase involved in the proliferation of cancer cells. Nature Cell Biology, 6:731-740, 2004
  230. S. Ashida, H.Nakagawa,T. Katagiri, M. Furihata, M.Iiizumi,Y.Anazawa.T. Tsunoda, R. Takata, K. Kasahara, T. Miki, T. Fujioka, T. Shuin, and Y. Nakamura: Molecular Features of the Transition from Prostatic Intraepithelial Neoplasia (PIN) to Prostate Cancer: Genome-wide Gene-expression Profiles of Prostate Cancers and PINs. Cancer Research, 64:5963-5972, 2004
  231. T. Nishidate, T. Katagiri, M.-L Lin, Y. Mano, Y. Miki, F. Kasumi, M. Yoshimoto, T. Tsunoda, K. Hirata, and Y. Nakamura: Genome-wide gene-expression profiles of breast-cancer cells purified with laser microbeam microdissection: Identification of genes associated with progression and metastasis. International Journal of Oncology, 25:797-819, 2004
  232. T. Mizuguchi, G. Collod-Beroud, T. Akiyama, M. Abifadel, N. Harada, T. Morisaki, D. Allard, M. Varret, M. Claustres, H. Morisaki, M. Ihara, A. Kinoshita, K. Yoshiura, C. Junien, T. Kajii, G. Jondeau, T. Ohta, T. Kishino, Y. Furukawa, Y. Nakamura, N. Niikawa, C. Boileau, and N. Matsumoto: Heterozygous TGFBR2 mutations in Marfan syndrome. Nature Genetics, 36:855-860, 2004
  233. M. Unoki, T. Nishidate, and Y. Nakamura: ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain. Oncogene, 23:7601-7610, 2004
  234. P.-C. Cha, R. Yamada, A. Sekine, Y. Nakamura, C.-L. Koha: Inference from the relationships between linkage disequilibrium and allele frequency distributions of 240 candidate SNPs in 109 drug-related genes in four Asian populations. Journal of Human Genetics, 49:558-572, 2004
  235. M. Takahashi, Y.-M. Lin, Y. Nakamura, and Y. Furukawa: Isolation and characterization of a novel gene CLUAP1 whose expression is frequently upregulated in colon cancer. Oncogene, 23:9289-9294, 2004
  236. Y. Yoshitake, T. Nakatsura, M. Monji, S. Senju, H. Matsuyoshi, H. Tsukamoto, S. Hosaka, H. Komori, D.Fukuma, Y. Ikuta, T. Katagiri, Y. Furukawa, H. Ito, M. Shinohara, Y. Nakamura, and Y. Nishimura: Proliferation potential-related protein, an ideal esophageal cancer antigen for immnotherapy, identified using complementary DNA microarray analysis. Clinical Cancer Research, 10:6437-6448, 2004
  237. R. Yagyu, Y. Furukawa, Y.-M. Lin, T. Shimokawa, T. Yamamura, and Y. Nakamura: A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer. International Journal of Oncology, 25:1343-1348, 2004
  238. M. Nishiu, Y. Tomita, S. Nakatsuka, T. Takakuwa, N. Iizuka, Y. Hoshida, J. Ikeda, K. Iuchi, R. Yanagawa, Y. Nakamura and K. Aozasa: Distinct pattern of gene expression in pyothorax-associated lymphoma(PAL),a lymphoma developing inlong-standing inflammation. Cancer Science, 95:828-834, 2004
  239. N. Ishikawa, Y. Daigo, W. Yasui, K. Inai, H. Nishimura, E. Tsuchiya, N. Kohno, and Y. Nakamura: ADAM8 as a novel serological and histochemical marker for lung cancer. Clinical Cancer Research, 10:8363-8370, 2004
  240. K. Okada, E. Hirota, Y. Mizutani, T. Fujioka, T. Shuin, T. Miki, Y. Nakamura and T. Katagiri: Oncogenic role of NALP7 in testicular seminomas. Cancer Science, 95:949-954, 2004
  241. K. Yamazaki, M. Takazoe, T. Tanaka, T. Ichimori, S. Saito, A. Iida, Y. Onouchi, A. Hata and Y. Nakamura: Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease. Journal of Human Genetics, 49:664-668, 2004
  242. T.Minaguchi, H. Yoshikawa, S. Nakagawa, T. Yasugi, T. Yano, H. Iwase, K. Mizutani, K. Shiromizu, K. Ohmi, Y. Watanabe, K. noda, M. Nishiu, Y. Nakamura, Y. Taketani: Association of PTEN mutation with HPV-negative adenocarcinoma of the uterine cervix. Cancer Letters, 210:57-62, 2004
  243. T.Nakatsura, H. Komori, T. Kudo, Y. Yoshitake, S. Senju, T. Katagiri, Y. Furukawa, M. Ogawa, Y. Nakamura and Y. Nishimura: Mouse homologue of a novel human oncofetal antigen, Glypican-3, evokes T-cell-mediated tumor rejection without autoimmune reactions in mice. Clinical Cancer Research, 10:8630-8640, 2004
  244. N. Uchida, T. Tsunoda, S. Wada, Y. Furukawa, Y. Nakamura, H. Tahara: Ring finger protein (RNF) 43 as a new target for cancer immunotherapy. Clinical Cancer Research, 10:8577-8586, 2004
  245. S. Kakiuchi, Y. Daigo, N. Ishikawa, C. Furukawa, T. Tsunoda, S. Yano, K. Nakagawa, T. Tsuruo, N. Kohno, M. Fukuoka, S. Sone, and Y. Nakamura: Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib. Human Molecular Genetics, 13:3029-3043, 2004
  246. H. Kamiyama, K. Kurosaki, M. Kurimoto, T. Katagiri, Y. Nakamura, M. Kurokawa, H. Sato, S. Endo andK. Shiraki: Herpes simplex virus induced death receptor-dependent apoptosis and regression of transplanted human cancers. Cancer Science, 95:990-998, 2004
  247. Y. Onouchi, S. Onoue, M. Tamari, K. Wakui, Y. Fukushima, M. Yashiro, Y. Nakamura, H. Yanagawa, F. Kishi, K. Ouchi, M. Terai, K. Hamamoto, F. Kudo, H. Aotsuka, Y. Sato, A. Nariai, Y. Kaburagi, M. Miura, T. Saji, T. Kawasaki, Y. Nakamura, and A. Hata: CD40 ligand gene and Kawasaki disease. Eur. J. Human Genetics, 12:1062-1068, 2004
  248. T. Hirota, K. Obara, A. Matsuda, M. Akahoshi, K. Nakashima, K. Hasegawa, N. Takahashi, M. Shimizu, H. Sekiguchi, M. Kokubo, S. Doi, H. Fujiwara, A. Miyatake, K. Fujita, T. Enomoto, F. Kishi, Y. Suzuki, H. Saito, Y. Nakamura, T. Shirakawa, and M. Tamari: Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma. Journal of Human Genetics, 49:370-5, 2004
  249. A. Kanazawa, S. Tsukada, A. Sekine, T. Tsunoda, A. Takahashi, A. Kashiwagi, Y. Tanaka, T. Babazono, M. Matsuda, K. Kaku, Y. Iwamoto, R. Kawamori, R. Kikkawa, Y. Nakamura, and S. Maeda; S. Tsukada, A. Sekine, T. Tsunoda, A. Takahashi, A. Kashiwagi, Y. Tanaka, T. Babazono, M. Matsuda, K. Kaku, Y. Iwamoto, R. Kawamori, R. Kikkawa, Y. Nakamura, and S. Maeda; Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes. Am. J. Human Genetics, 75:832-843, 2004

    2005　　↑ページトップへ

  250. S. Ohtsubo, A. Iida, K. Nitta, T. Tanaka, R. Yamada, Y. Ohnishi, S. Maeda, T. Tsunoda, T. Takei, W. Obara, F. Akiyama, K. Ito, K. Honda, K. Uchida, K. Tsuchiya, W. Yumura, T. Ujiie, Y. Nagane, S. Miyano, Y. Suzuki, I. Narita, F. Gejyo, T. Fujioka, H. Nihei and Y. Nakamura: Association of a single-nucleotide polymorphism in the immunoglobulin μ-binding protein 2 gene with immunoglobulin A nephropathy. Journal of Human Genetics, 50:30-35, 2005
  251. F. P. Silva, R. Hamamoto, Y. Nakamura, and Y. Furukawa: WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation. Neoplasia, 7:348-355, 2005
  252. A. Iida, K. Ozaki, T. Tanaka, and Y. Nakamura: Fine-scale SNP map of an 11-kb genomic region at 22q13.1 containing the galectin-1 gene. Journal of Human Genetics, 50:42-45, 2005
  253. W.-R. Park, Y. Nakamura: p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway. Cancer Research, 65:1197-1206, 2005
  254. K. Taniuchi, K. Taniuchi, H. Nakagawa, M.Hosokawa, T. Nakamura, H. Eguchi, H. Ohigashi, O. Ishikawa, T. Katagiri, and Y. Nakamura: Overexpressed P-cadherin/CDH3 promotes motility of pancreatic cancer cells by interacting with p120ctn and activating Rho-family GTPases. Cancer Research, 65:3092-3099, 2005
  255. R. Takata, T. Katagiri, M. Kanehira, T. Tsunoda, T. Shuin, T. Miki, M. Namiki, K. Kohri, Y. Matsushita, T. Fujioka and Y. Nakamura: Predicting response to methotrexate,vinblastine,doxorubicin,and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling. Clinical Cancer Research, 11:2625-2636, 2005
  256. H. Kizawa, I. Kou, A. Iida, A. Sudo, Y. Miyamoto, A. Fukuda, A. Mabuchi, A. Kotani, A. Kawakami, S. Yamamoto, N. Uchida, K. Nakamura, K. Notoya, Y. Nakamura and S. Ikegawa: An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis. Nature Genetics, 37:138-144, 2005
  257. L. Yang, A. C. C. Leung, J. M. Y. Ko, P. H. Y. Lo, J. C. O. Tang, G. Srivastava, M. Oshimura, E. J. Stanbridge, Y. Daigo, Y. Nakamura, C. M. C. Tang, K. W. Lau, S. Law and M. L. Lung: Tumor suppressive role of a 2.4 Mb 9q33-q34 critical region and DEC1 in esophageal squamous cell carcinoma. Oncogene, 24:697-705, 2005
  258. K.Taniuchi, H. Nakagawa, T. Nakamura, H. Eguchi, H. Ohigashi, O. Ishikawa, T. Katagiri, and Y. Nakamura: Down-regulation of RAB6KIFL / KIF20A, a kinesin involved with membrane trafficking of discs large homolog 5, can attenuate growth of pancreatic cancer cells. Cancer Research, 65:105-112, 2005
  259. A. Iida, Y. Nakamura: Identification of 156 novel SNPs in 29 genes encoding G-protein coupled receptors. Journal of Human Genetics, 50:182-191, 2005
  260. Y. Anazawa, H. Nakagawa, M. Furihara, S. Ashida, K. Tamura, H. Yoshioka, T. Shuin, T. Fujioka, T. Katagiri, and Y. Nakamura: PCOTH, a novel gene over-expressed in prostate cancers, promotes prostate cancer cell growth through phosphorylation of oncoprotein TAF-Ib/SET. Cancer Research, 65:4578-4586, 2005
  261. A. Togashi, T. Katagiri, S. Ashida, T. Fujioka, O. Maruyama, Y. Wakumoto, Y. Sakamoto, M. Fujime, Y. Kawachi, T. Shuin and Y. Nakamura: Hypoxia-inducible protein 2 (HIG2), a novel diagnostic marker for renal cell carcinoma and potential target for molecular therapy. Cancer Research, 65:4817-4826, 2005
  262. S. Nagayama, C. Fukukawa, T. Katagiri, T. Okamoto, T. Aoyama, N. Oyaizu, M. Imamura, J. Toguchida and Y. Nakamura: Therapeutic potential of antibodies against FZD10, a cell-surface protein, for synovial sarcomas. Oncogene, 24:6201-6212, 2005
  263. H. Mototani, A. Manuchi, S. Saito, M. Fujioka, A. Iida, Y. Takatori, A. Kotani, T. Kubo, K. Nakamura, A. Sekine, Y. Murakami, T. Tsunoda, K. Notoya, Y. Nakamura and S. Ikegawa: A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese. Human Molecular Genetics, 14:1009-1017, 2005
  264. K. Obama, K. Ura, M. Li, T. Katagiri, T. Tsunoda, A. Nomura, S. Satoh, Y. Nakamura, and Y. Furukawa: Genome-wide analysis of gene expression in human intrahepatic cholangiocarcinomas. Hepatology, 41:1339-1348, 2005
  265. K. Obama, K. Ura, S. Satoh, Y. Nakamura, and Y. Furukawa: Up-regulation of PSF2, a member of the GINS multiprotein complex , in intrahepatic cholangiocarcinoma. Oncology Report, 14:701-706, 2005
  266. T. Watanabe, T. Suda, T. Tsunoda, N. Uchida, K. Ura, T. Kato, S. Hasegawa, S. Satoh, S. Ohgi, H. Tahara, Y. Furukawa and Y. Nakamura: Identification of Immunoglobulin superfamily 11 (IGSF11) as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas. Cancer Science, 96:498-506, 2005
  267. S. Maeda, S. Tsukada, A. Kanazawa, A. Sekine, T. Tsunoda, D. Koya, H. Maegawa, A. Kashiwagi, T. Babazono, M. Matsuda, Y. Tanaka, T. Fujioka, H. Hirose, T. Eguchi, Y. Ohno, C. Groves, A. Hattersley, G. Hitman, M. Walker, K. Kaku, Y. Iwamoto, R. Kawamori, R. Kikkawa, N. Kamatani, M. McCarthy, and Y. Nakamura: Genetic Variations in the gene encoding TFAP2B are associated with type 2 diabetes. Journal of Human Genetics, 50:283-292, 2005
  268. S.Shimazaki, Y. Kawamura, A. Kanazawa, A. Sekine, S. Saito, T. Tsunoda, D. Koya, T. Babazono, Y. Tanaka, M. Matsuda, K. Kawai, T. Iiizumi, M. Imanishi, T. Shinosaki, T. Yanagimoto, M. Ikeda, S. Omachi, A. Kashiwagi, K. Kaku, Y. Iwamoto, R. Kawamori, R. Kikkawa, M. Nakajima, Y. Nakamura, and S. Maeda: Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy. Diabetes, 54:1171-1178, 2005
  269. M.Akahoshi, K. Obara, T. Hirota, A. Matsuda, K. Hasegawa, N. Takahashi, M. Shimizu, K. Nakashima, L. Cheng, S. Doi, H. Fujiwara, A. Miyatake, K. Fujita, N. Higashi, M. Taniguchi, T. Enomoto, X.Q. Mao, H. Nakashima, C.N. Adra, Y. Nakamura, M. Tamari, and T. Shirakawa : Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma. Human Genetics, 117:16-26, 2005
  270. T. Kato, Y. Daigo, S. Hayama, N. Ishikawa, T. Yamabuki, T. Ito, M. Miyamoto, S. Kondo and Y. Nakamura: A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis. Cancer Research, 65:5638-5646, 2005
  271. K. Asamura, S. Abe, Y. Imamura, A. Aszodi, N. Suzuki, S. Hashimoto, Y. Takumi, T. Hayashi, R. Fassler, Y. Nakamura, and S. Usami: Type IX collagen is crucial for normal hearing. Neuroscience, 132:493-500, 2005
  272. R. Kawaida, R. Yamada, K. Kobayashi, S. Tokuhiro, A. Suzuki, Y Kochi, X. Chang, A. Sekine, T. Tsunoda, T. Sawada, H. Furukawa, Y. Nakamura, and K. Yamamoto: CUL1, a component of E3 ubiquitin ligase, alters lymphocyte signal transduction with possible effect on rheumatoid arthritis. Genes Immun, 6:194-202, 2005
  273. S. Seki, Y. Kawaguchi, K. Chiba, Y. Mikami, H. Kizawa, T. Oya, F. Mio, M. Mori, Y. Miyamoto, I. Masuda, T. Tsunoda, M. Kamata, T. Kubo, Y. Toyama , T. Kimura, Y. Nakamura and S. Ikegawa: A functional SNP in CLIP , encoding cartilage intermediate layer protein , is associated with susceptibility to lumbar disc disease. Nature Genetics, 37:607-612, 2005
  274. Y. Kochi, R. Yamada, A. Suzuki, J. B. Harley, S. Shirasawa, T. Sawada, S. C. Bae, S. Tokuhiro, X. Chang, A. Sekine, A. Takahashi, T. Tsunoda, Y. Ohnishi, K. M. Kaufman, C. P. Kang, C. Kang, S. Otsubo, W. Yumura, A. Mimori, T. Koike, Y. Nakamura, T. Sasazuki and K. Yamamoto: A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. Nature Genetics, 37:478-485, 2005
  275. C. Furukawa, Y. Daigo, N. Ishikawa, T. Kato, T. Ito, E. Tsuchiya, S. Sone, and Y. Nakamura: Plakophilin 3 oncogene as prognostic marker and therapeutic target for lung cancer. Cancer Research, 65:7102-7110, 2005
  276. M. Tsuge, R. Hamamoto, F. P. Silva, Y. Ohnishi, K. Chayama, N. Kamatani, Y. Furukawa, and Y. Nakamura: A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5' flanking region of SMYD3 is a risk factor for human cancers. Nature Genetics, 37:1104-1107, 2005
  277. M. Sakai, T. Shimokawa, T. Kobayashi, S. Matsushima, Y. Yamada, Y. Nakamura, and Y. Furukawa: Elevated expression of C10orf3 (chromosome 10 open reading frame 3) is involved in the growth of human colon tumor. Oncogene, 25:480-486, 2005
  278. M. Takahashi, Y. Nakamura, K. Obama, and Y. Furukawa: Identification of SP5 as a downstream gene of the β-catenin/Tcf pathway and its enhanced expression in human colon cancer. International Journal of Oncology, 27:1483-1487, 2005
  279. N. Ishikawa, Y. Daigo, A. Takano, M. Taniwaki, T. Kato, S. Hayama, H. Murakami, Y. Takeshima, K. Inai, H. Nishimura, E. Tsuchiya, N. Kohno, and Y. Nakamura: Increases of amphiregulin and transforming growth factor-α in serum as predictors of poor response to Gefitinib among patients with advanced non-small cell lung cancers. Cancer Research, 65:9176-9184, 2005
  280. C. Suzuki, Y. Daigo, N. Ishikawa, T. Kato, S. Hayama, T. Ito, E. Tsuchiya, and Y. Nakamura: ANLN plays a critical role in human lung carcinogenesis through the activation of RHOA and by involvement in the phosphoinositide 3kinase/AKT pathway. Cancer Research, 65:11314-11325, 2005
  281. K. Asamura, S. Abe,H. Fukuoka,Y. Nakamura,S. Usami: Mutation analysis of COL9A3, a gene highly expressed in the cochlea, in hearing loss patients. Auris Nasus Larynx, 32:113-117, 2005
  282. A. Kanazawa, Y. Kawamura,A. Sekine,A. Iida,T. Tsunoda,A. Kashiwagi,Y. Tanaka,T. Babazono,M. Matsuda,K. Kawai,T. Iiizumi,T. Fujioka,M. Imanishi,K. Kaku,Y. Iwamoto,R. Kawamori,R. Kikkawa,Y. Nakamura, and S.Maeda: Single nucleotide polymorphosms in the gene encoding Kruppel-like factor 7 are associated with type 2diabetes. Diabetologia, 48:1315-1322, 2005
  283. C. Furukawa, Y. Nakamura and T. Katagiri: Molecular target therapy for synovial sarcoma. Future Oncology, 1:805-812, 2005
  284. T. Watanabe, M. Suzuki,Y. Yamasaki,S. Okuno,H. Hishigaki,T. Ono,K. Oga,A. Mizoguchi-Miyakita,A. Tsuji,N. Kanemoto,S. Wakitani,T. Takagi,Y. Nakamura, and A. Tanigami: Mutated G-protein-coupled receptor GPR10 is responsible for the hyperphagia/dyslipidaemia/obesity locus of Dmol in the OLETD rat. Clinical and Experimental Pharmacology and Physiology, 32:355-366, 2005
  285. K. Yamazaki, D. McGovern, J. Ragoussis, M. Paolucci, H. Butler, D. Jewell, L. Cardon, M. Takazoe, T. Tanaka, T. Ichimori, S. Saito, A. Sekine, A. Iida, A. Takahashi, T. Tsunoda, M. Lathrop, and Y. Nakamura: Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Human Molecular Genetics, 14:3499-3506, 2005
  286. The International HapMap Consortium: A haplotype map of the human genome. Nature, 437:1299-1320, 2005
  287. T. Ishibe, T. Nakayama, T. Okamoto, T. Aoyama, K. Nishijo, K. Shibata,Y. Shima, S. Nagayama, T. Katagiri,Y. Nakamura, T. Nakamura, and J. Toguchida: Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas:potential application of signal inhibitor to molecular target therapy. Clinical Cancer Research, 11:2702-2712, 2005
  288. T. Hirota, Y. Suzuki, K. Hasegawa, K. Obara, A. Matsuda, M. Akahoshi, K. Nakashima, L. Cheng, N. Takahashi, M. Shimizu, S. Doi, K. Fujita, T. Enomoto, M. Ebiwsawa, S. Yoshihara, Y. Nakamura, F. Kishi, T. Shirakawa, and M. Tamari: Functional haplotypes of IL-12B are associated with childhood atopic asthma. J allergy Clin Immunol, 116:789-795, 2005
  289. A. Matsuda, T. Hirota, M. Akahoshi, M. Shimizu, M. Tamari, A. Miyatake, A. Takahashi, K. Nakashima, N. Takahashi, K. Obara, N.Yuyama, S. Doi, Y. Kamogowa, T. Enomoto, K. Ohshima, T. Tsunoda, S. Miyatake, K. Fujita, M. Kusakabe, K. Izuhara, Y. Nakamura, J. Hopkin, and T.Shirakawa: Coding SNP in tenascin-C Fn-Ⅲ-D domain associates with adult asthma. Human Molecular Genetics, 14:2779-2786, 2005
  290. T. Mushiroda, S. Saito, Y. Tanaka, J. Takasaki, N. Kamatani, Y. Beck, H. Tahara, Y. Nakamura, and Y. Ohnishi: A model of prediction system for adverse cardiovascular reactions by calcineurin inhibitors among patients with renal transplants using gene-based single-nucleotide polymorphisms. Journal of Human Genetics, 50:442-447, 2005

    2006　　↑ページトップへ

  291. R. Hamamoto, F. P. Silva, M. Tsuge, T. Nishidate, T. Katagiri, Y. Nakamura and Y. Furukawa: Enhanced SMYD3 expression is essential for the growth of breast cancer cells. Cancer Science, 97:113-118, 2006
  292. K. Obama, T. Kato, S. Hasegawa, S. Satoh, Y. Nakamura, and Y. Furukawa: Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells. Clinical Cancer Research, 12:70-76, 2006
  293. A. Iida, S. Saito, A. Sekine, A. Takahashi, N. Kamatani, and Y. Nakamura: Japanese single nucleotide polymorphism database for 267 possible drug-related genes. Cancer Science, 97:16-24, 2006
  294. T. Kikuchi, Y. Daigo, N. Ishikawa, T. Katagiri, T. Tsunoda, S. Yoshida, and Y. Nakamura: Expression profiles of metastatic brain tumor from lung adenocarcinomas on cDNA microarray. International Journal of Oncology, 28:799-805, 2006
  295. T. Mushiroda, Y. Ohnishi, S. Saito, A. Takahashi, Y. Kikuchi, S. Saito, H. Shimomura, Y. Wanibuchi, T. Suzuki, N. Kamatani, and Y. Nakamura: Association of VKORC1 and CYP2C9 polymorphisms with warfarin dose requirements in Japanese patients. Journal of Human Genetics, 51:249-253, 2006
  296. T. Suda, T. Tsunoda, N. Uchida, T. Watanabe, S. Hasegawa, S. Satoh, S. Ohgi, Y. Furukawa, Y. Nakamura, and H. Tahara: Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray. Cancer Science, 97:411-419, 2006
  297. K. Yoshiura, A. Kinoshita, T. Ishida, A. Ninokata,T. Ishikawa, T. Kaname, M. Bannai, K. Tokunaga, S. Sonoda, R. Komaki, M. Ihara, V. Saenko, A. G. Kaimovich, I. Sekine, K. Komatsu, H. Takahashi, M. Nakashima, N. Sosonkina, C. K. Mapendano, M. Ghadami, M. Nomura, D.-S. Linag, D.-K. Kim, A. Garidkhuu, N. Natsume, T. Ohta, H. Tomita, K. Hirayama, M. Ishibashi, A. Takahashi, N. Saito, S. Saitou, Y. Nakamura, and N, Niikawa: A SNP in the ABCC11 gene is the determinant of human earwax type. Nature Genetics, 38:324-330, 2006
  298. T. Yamabuki, Y. Daigo, T. Kato, S. Hayama, T. Tsunoda, M. Miyamoto, T. Ito, M. Fujita, M. Hosokawa, S. Kondo, and Y. Nakamura: Genome-wide gene expression profile analysis of esophageal squamous cell carcinomas. International Journal of Oncology, 28:1375-1384, 2006
  299. A. Iida, H. Kizawa, Y. Nakamura, and S. Ikegawa: High-resolution SNP map of ASPN, a susceptibility gene for osteoarthritis. Journal of Human Genetics, 51:151-154, 2006
  300. F. P. Silva, R. Hamamoto, Y. Furukawa, and Y. Nakamura: TIPUH1 encodes a novel KRAB zinc- finger protein highly expressed in human hepatocellular carcinomas. Oncogene, 25:5063-5070, 2006
  301. K. Nakashima, T. Hirota, Y. Suzuki, A. Matsuda, M. Akahoshi, M. Shimizu, A. Jodo, S. Doi, K. Fujita, M. Ebisawa, S. Yoshihara,T. Enomoto, T. Shirakawa, F. Kishi, Y. Nakamura, and M. Tamari: Association of the RIP2 gene with childhood atopic asthma. Alleology International, 1:77-83, 2006
  302. K. Nakashima, T. Hirota, K. Obara, M. Shimizu, A. Jodo, M. Kameda, S. Doi, K. Fujita, T. Shirakawa, T. Enomoto, F. Kishi, S. Yoshihara, K. Matsumoto, H. Saito, Y. Suzuki, Y.Nakamura, and M. Tamari: An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway. Journal of Human Genetics, 51:284-291, 2006
  303. S. Ashida, M. Furihata, T. Katagiri, K. Tamura, Y. Anazawa, H. Yoshioka, T. Miki, T. Fujioka, T. Shuin, Y. Nakamura, and H. Nakagawa: Expression of novel molecules, MICAL2-PV (MICAL2 prostate cancer variants), increases with high gleason score and prostate cancer progression. Clinical Cancer Research, 12:2767-2773, 2006
  304. N. Ishikawa, Y. Daigo, A. Takano, M. Taniwaki, T. Kato, S. Tanaka, W. Yasui, Y. Takeshima, K. Inai, H. Nishimura, E. Tsuchiya, N. Kohno, and Y. Nakamura: Characterization of SEZ6L2 cell-surface protein as a novel prognostic marker for lung cancer. Cancer Science, 97:737-745, 2006
  305. T. Kobayashi, T. Masaki, M. Sugiyama, Y. Atomi, Y. Furukawa, and Y. Nakamura: A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells. International Journal of Oncology, 29:341-347, 2006
  306. M. Taniwaki, Y. Daigo, N. Ishikawa, A. Takano, T. Tsunoda, W. Yasui, K. Inai, N. Kohno, and Y. Nakamura: Gene expression profiles of small-cell lung cancers: molecular signatures of lung cancer. International Journal of Oncology, 29:567-575, 2006
  307. E. Hirota, L. Yan, T. Tsunoda, S. Ashida, M. Fujime, T. Shuin, T. Miki, Y. Nakamura and T. Katagiri: Genome-wide gene expression profiles of clear cell renal cell carcinoma; International Journal of Oncology, 29:799-827, 2006
  308. J.-H. Park, M.-l. Lin, T. Nishidate, Y. Nakamura, and T. Katagiri: PDZ-binding kinase/T-LAK cell-originated protein kinase, a putative cancer/testis antigen with an oncogenic activity in breast cancer. Cancer Research, 66:9186-9195, 2006
  309. K. Ozaki, H. Sato, A. Iida, H. Mizuno, T. Nakamura, Y. Miyamoto, A. Takahashi, T. Tsunoda, S. Ikegawa, N. Kamatani, M. Hori, Y. Nakamura, and T. Tanaka: A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population. Nature Genetics, 38:921-925, 2006
  310. N. Jinawath, Y. Chamgramol, Y. Furukawa, K. Obama, T. Tsunoda, B. Sripa, C. Pairojkul, and Y. Nakamura: Comparison of gene-expression profiles between opisthorchis viverrini and non-opisthorchis viverrini associated human intrahepatic cholangiocarcinoma. Hepatology, 44:1025-1038, 2006
  311. Y. Nakamura, M. Futamura, H. Kamino,K. Yoshida,Y. Nakamura, and H. Arakawa: Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis. Cancer Science, 97:633-641, 2006
  312. A. Takehara, H. Eguchi, H. Ohigashi, O. Ishikawa, T. Kasugai, M. Hosokawa, T. Katagiri, Y. Nakamura, and H. Nakagawa: Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4. Cancer Science, 97:1191-1197, 2006
  313. M. Iiizumi, H. Nakagawa, M. Hosokawa, A. Takehara, C. Su-Youn, T. Nakamura, T. Katagiri, H. Eguchi, H. Ohigashi, O. Ishikawa, Y. Nakamura, and H. Nakagawa: EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth. Cancer Science, 97:1211-1216, 2006
  314. K. Takahashi, C. Furukawa, A. Takano, N. Ishikawa, T. Kato, S. Hayama, C. Suzuki, W. Yasui, K. Inai, S. Sone, T. Ito, H. Nishimura, E. Tsuchiya, Y. Nakamura and Y. Daigo: The neuromedin u-growth hormone secretagogue receptor 1b/neurotensin receptor 1 oncogenic signaling pathway as a therapeutic target for lung cancer. Cancer Research, 66:9408-9419, 2006
  315. S. Hayama, Y. Daigo, T. Kato, N. Ishikawa, T. Yamabuki, M. Miyamoto, T. Ito, E. Tsuchiya, S. Kondo, and Y. Nakamura: Activation of CDCA1-KNTC2, members of centromere protein complex, involved in pulmonary carcinogenesis. Cancer Research, 66:10339-10348, 2006
  316. K. Ura, K. Obama, S. Satoh, Y. Sakai, Y. Nakamura, and Y. Furukawa: Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma. Clinical Cancer Research, 12:6611-6616, 2006
  317. N. Ishii, K. Ozaki, H. Sato, H. Mizuno, S. Saito, A. Takahashi, Y. Miyamoto, S. Ikegawa, N. Kamatani, M. Hori, S. Saito, Y. Nakamura and T. Tanaka: Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial Infarction. Journal of Human Genetics, 51:1087-1099, 2006
  318. S. Mahasirimongkol, W. Chantratita, S. Promso, E. Pasomsab, N. Jinawath, W. Jongjaroenprasert, V. Lulitanond, P. Krittayapoositpot, S. Tongsima, P. Sawanpanyalert, N. Kamatani, Y. Nakamura, T. Sura: Similarity of the allele frequency and linkage disequilibrium pattern of single nucleotide polymorphisms in drug-related gene loci between Thai and northern East Asian populations: implications for tagging SNP selection in Thais. Journal of Human Genetics, 51:896-904, 2006
  319. Y. Nakazaki, H. Hase, H. Inoue, Y.Beppu, M. Xin, G. Sakaguchi, R. Kurita, S. Asano, Y. Nakamura, and K. Tani: Serial analysis of gene expression in progressing and regressing mouse tumor implicates the involvement of RANTES andTARC in antitumor immune responses. Molecular Therapy, 14:599-606, 2006
  320. A. Shimo, T. Nishidate, T. Ohta, M. Fukuda and Y. Nakamura, and T. Katagiri: Elevated expression of protein regulator of cytokinesis 1, involved in the growth of breast cancer cells. Cancer Science, 98:174-181, 2006
  321. M. Kato, A. Sekine, Y. Ohnishi, T. A. Johnson, T. Tanaka, Y. Nakamura, and T. Tsunoda: Linkage disequilibrium of evolutionarily conserved regions in the human genome. BMC Genomics, 7:326-333, 2006

    2007　　↑ページトップへ

  322. T. Kato, S. Hayama, T. Yamabuki, N. Ishikawa, M. Miyamoto, T. Ito, E. Tsuchiya, S. Kondo, Y. Nakamura, and Y. Daigo: Increased expression of insulin-like growth factor-Ⅱ messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer. Clinical Cancer Research, 13:434-442, 2007
  323. M. Kanehira, T. Katagiri, A. Shimo, R. Takata, T. Shuin, T. Miki, T. Fujioka, and Y. Nakamura: Oncogenic role of MPHOSPH1, a cancer-testis antigen specific to human bladder cancer. Cancer Research, 67:3276-3285, 2007
  324. M. Kubo, J. Hata, T. Ninomiya, K. Matsuda, K. Yonemoto, T. Nakano, T. Matsushita, K. Yamazaki, Y. Ohnishi, S. Saito, T. Kitazono, S. Ibayashi, K. Sueishi, M. Iida, Y. Nakamura, and Y. Kiyohara: A nonsynonymous SNP in PRKCH increases the risk of cerebral infarction. Nature Genetics, 39:212-217, 2007
  325. C. Suzuki, K. Takahashi, S. Hayama, N. Ishikawa, T. Kato, T. Ito, E. Tsuchiya, Y. Nakamura, and Y. Daigo: Identification of Myc-assocaited protein with JmjC domain as a novel therapeutic target oncogene for lung cancer. Molecular Cancer Therapeutics, 6:542-551, 2007
  326. T. Yamabuki, A. Takano, S. Hayama, N. Ishikawa, T. Kato, M. Miyamoto, T. Ito, H. Ito, Y. Miyagi, H. Nakayama, M. Fujita, M. Hosokawa, E. Tsuchiya, N. Kohno, S. Kondo, and Y. Nakamura, and Y. Daigo: Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas. Cancer Research, 67:2517-2525, 2007
  327. K. Saigusa, I. Imoto, C. Tanikawa, M. Aoyagi, K. Ohno, Y. Nakamura, and J. Inazawa: A functional SNP in ITIH3 is associated with susceptibility to myocardial infarction. Oncogene, 26:1110-1121, 2007
  328. Y. Ebana, K. Ozaki, K. Inoue, H. Sato, A. Iida, H. Lwin, S. Saito, H. Mizuno, A. Takahashi, T. Nakamura, Y. Miyamoto, S. Ikegawa, K. Odashiro, M. Nobuyoshi, N. Kamatani, M. Hori, M. Isobe, Y. Nakamura and T. Tanaka: A functional SNP in ITIH3 is associated with susceptibility to myocardial infarction. Journal of Human Genetics, 52:220-229, 2007
  329. M.-L. Lin, J.-H. Park, T. Nishidate, Y. Nakamura, and T. Katagiri: Involvement of maternal embryonic leucine zipper kinase (MELK), in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family. Breast Cancer Research, 9:R17, 2007
  330. R. Takata, T. Katagiri, M. Kanehira, T. Shuin, T. Miki, M. Namiki, K. Kohri, T. Tsunoda, T. Fujioka, and Y. Nakamura: Validation study of the prediction system for clinical response of M-VAC neoadjuvant chemotherapy. Cancer Science, 98:113-117, 2007
  331. M. Hosokawa, A. Takehara, K. Matsuda, H. Eguchi, H. Ohigashi, O. Ishikawa, Y. Shinomura, K. Imai, Y. Nakamura, and H. Nakagawa: Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer. Cancer Research, 67:2568-2576, 2007
  332. J. Hata, K. Matsuda, T. Ninomiya, K. Yonemoto, T. Matsushita, Y. Ohnishi, S. Saito, T. Kitazono, S. Ibayashi, M. Iida, Y. Kiyohara, Y. Nakamura, and M. Kubo: Functional SNP in a Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction. Human Molecular Genetics, 16:630-639, 2007
  333. N. Osawa, D. Koga, S. Araki, T. Uzu,T. Tsunoda, A. Kashiwagi, Y. Nakamura, and S. Maeda: Combinational effect of genes for the renin-angiotensin system in conferring susceptibility to diabetic nephropathy. Journal of Human Genetics, 52:143-151, 2007
  334. Y. Onouchi, M. Tamari, A. Takahashi, T. Tsunoda, M. Yashiro, Yo. Nakamura, H. Yanagawa, K. Wakui, Y. Fukushima, T. Kawasaki, Yu. Nakamura, and A. Hata: A gennomewide linkage analysis of Kawasaki disease:evidence for linkage to chromosome 12. Journal of Human Genetics, 52:179-190, 2007
  335. Y. Miyamoto, A. Mabuchi, D. Shi, T. Kubo, Y. Takatori, S. Saito, M. Fujioka, A. Sudo, A. Uchida, S. Yamamoto, K. Ozaki, M. Takigawa, T. Tanaka, Y. Nakamura, Q. Jiang, and S. Ikegawa: A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis. Nature Genetics, 39:529-533, 2007
  336. M. Kanehira, Y. Harada, R. Takata, T. Shuin, T. Miki, T. Fujioka, Y. Nakamura, and T. Katagiri: Involvement of upregulation of DEPDC1 (DEP domain containing 1) in bladder carcinogenesis. Oncogene, 26:6448-6455, 2007
  337. S. Hayama, Y. Daigo, T. Yamabuki, D. Hirata, T. Kato, M. Miyamoto, T. Ito, E. Tsuchiya, S. Kondo, and Y. Nakamura: Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis. Cancer Research, 67:4113-4122, 2007
  338. K. Tamura, M. Furihata, T. Tsunoda, S. Ashida, R. Takata, W. Obara, H. Yoshioka, Y. Daigo, Y. Nasu, H. Kumon, H. Konaka, M. Namiki, K. Tozawa, K. Kohri, N. Tanji, M. Yokoyama, T. Shimazui, H. Akaza, Y. Mizutani, T. Miki, T. Fujioka, T. Shuin, Y. Nakamura, and H. Nakagawa: Molecular features of hormone-refractory prostate cancer cells by genome-wide gene expression profiles. Cancer Research, 67:5117-5125, 2007
  339. A. Bourdon, L. Minai, V. Serre, J.-P. Jais, E. Sarzi, S. Aubert, D. Chretien, P. de Lonlay, V. Paquis-Flucklinger, H. Arakawa, Y. Nakamura, A. Munnich, and A. Rotig: Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion. Nature Genetics, 39:776-780, 2007
  340. K. M. Giacomini, R. M. Krauss, D. M. Roden, M. Eichelbaum, M. R. Hayden, and Y. Nakamura: When good drugs go bad (commentary). Nature, 446:975-977, 2007
  341. H. Zembutsu, M. Yanada, A. Hishida, T. Katagiri, T. Tsuruo, I. Sugiura, J. Takeuchi, N. Usui, T. Naoe, Y. Nakamura, and R. Ohno: Prediction of risk of disease recurrence by genome-wide cDNA microarray analysis in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy. International Journal of Oncology, 31:313-322, 2007
  342. M. Fujikawa, T. Katagiri, A. Tugores, Y. Nakamura, and F. Ishikawa: ESE-3, an Ets family transcription factor, Is up-regulated in cellular senescence. Cancer Science, 98:1468-1475, 2007
  343. T. Kato, N. Sato, S. Hayama, T. Yamabuki, T. Ito, M. Miyamoto, S. Kondo, Y. Nakamura, and Y. Daigo: Activation of　Holliday Junction-Recognizing Protein involved in the chromosomal stability and immortality of cancer cells. Cancer Research, 67:8544-8553, 2007
  344. K. Ueda, T. Katagiri, T. Shimada, S. Irie, T. Sato, Y. Nakamura, and Y. Daigo: Comparative profiling of serum glycoproteome by sequential purification of glycoproteins and 2-nitrobenzensulfenyl (NBS) stable isotope labeling: a new approach for the novel biomarker discovery for cancer. Journal of Proteome Research, 6:3475-3483, 2007
  345. M. Taniwaki, A. Takano, N. Ishikawa, W. Yasui, K. Inai, H. Nishimura, E. Tsuchiya, N. Kohno, Y. Nakamura, and Y. Daigo: Activation of KIF4A as a prognostic biomarker and therapeutic target for lung cancer. Clinical Cancer Research, 13:6624-6631, 2007
  346. T. Suda, T. Tsunoda, Y. Daigo, Y. Nakamura, and H. Tahara: Identification of HLA-A24-restricted epitope-peptides derived from gene products up-regulated in lung and esophageal cancers as novel targets for immunotherapy. Cancer Science, Sep 2:Epub ahead of print, 2007
  347. Y. Mano, K. Takahashi, N. Ishikawa, A. Takano, W. Yasui, K. Inai, H. Nishimura, E. Tsuchiya, Y. Nakamura, and Y. Daigo: Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer. Cancer Science, 98:1902-1913, 2007
  348. S. Senju, H. Suemori, H. Zembutsu, Y. Uemura, S. Hirata, D. Fukuma, H. Matsuyoshi, M. Shimomura, M. Haruta, S. Fukushima, Y. Matsunaga, T. Katagiri, Y. Nakamura, M. Furuya, N. Nakatsuji, and Y. Nishimura: Genetically manipulated human embryonic stem cell-derived dendritic cells with immune regulatory function. Stem Cells, 25:2720-2729, 2007
  349. P.-C. Cha, T. Mushiroda, A. Takahashi, S. Saito, H. Shimomura, Y. Wanibuchi, T. Suzuki, N. Kamatani, and Y. Nakamura: High-resolution SNP and haplotype maps of the human gamma-glutamyl carboxylase gene (GGCX) and association study between polymorphisms in GGCX and the warfarin maintenance dose requirement of the Japanese population. Journal of Human Genetics, 52:856-864, 2007
  350. K. Yamazaki, Y. Onouchi, M. Takazoe, M. Kubo, Y. Nakamura, and A. Hata: Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients. Journal of Human Genetics, 52:575-583, 2007
  351. Y. Tsukumo, A. Tomida, O. Kitahara, Y. Nakamura, S. Asada, K. Mori, and T. Tsuruo: Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation. Journal of Biological Chemistry, 282:29264-29272, 2007
  352. A. Takehara, M. Hosokawa, H. Eguchi, H. Ohigashi, O. Ishikawa, Y. Nakamura, and H. Nakagawa: γ-aminobutyric acid (GABA) stimulates pancreatic cancer growth through overexpressing GABAA receptor π subunit. Cancer Research, 67:9704-9712, 2007
  353. T. Kidokoro, C. Tanikawa, Y. Furukawa, T. Katagiri, Y. Nakamura, and K. Matsuda: CDC20, a potential cancer therapeutic target, is negatively regulated by p53. Oncogene, 27:1562-1571, 2007
  354. M. Kunizaki, R. Hamamoto, F. P. Silva, K. Yamaguchi, T. Nagayasu, M. Shibuya, Y. Nakamura, and Y. Furukawa: The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3. Cancer Research, 67:10759-10765, 2007
  355. S. Kudo , R. Konda, W. Obara, D. Kudo, K. Tani, Y. Nakamura, and T. Fujioka: Inhibition of tumor growth through suppression of angiogenesis by brain-specific angiogenesis inhibitor 1 gene transfer in murine renal cell carcinoma. Oncology Reports, 18:785-791, 2007
  356. The International HapMap Consortium: A second generation human haplotype map of over 3.1 million SNPs. Nature, 449:851-861, 2007
  357. P. C. Sabeti, P. Varilly, B. Fry, J. Lohmueller, E. Hostetter, C. Cotsapas, X. Xie, E. H. Byrne, S. A. McCarroll, R. Gaudet, S. F. Schaffner, E. S. Lander, and The International HapMap Consortium: Genome-wide detection and characterization of positive selection in human populations. Nature, 449:913-918, 2007
  358. N. Ishikawa, A. Takano, W. Yasui, K. Inai, H. Nishimura, H. Ito, Y. Miyagi, H. Nakayama, M. Fujita, M. Hosokawa, E. Tsuchiya, N. Kohno, Y. Nakamura, and Y. Daigo: Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas. Cancer Research, 67:11601-11611, 2007
  359. T. Yanagiya, A. Tanabe, A. Iida, S. Saito, A. Sekine, A. Takahashi, T. Tsunoda, S. Kamohara, Y. Nakata, K. Kotani, R. Komatsu, N. Itoh, I. Mineo, J. Wada, H. Masuzaki, M. Yoneda, A. Nakajima, S. Miyazaki, K. Tokunaga, M. Kawamoto, T. Funahashi, K. Hamaguchi, K. Tanaka, K. Yamada, T. Hanafusa, S. Oikawa, H. Yoshimatsu, K. Nakao, T. Sakata, Y. Matsuzawa, N. Kamatani, Y. Nakamura, and K. Hotta: Association of single-nucleotide polymorphisms in MTMR9 gene with obesity. Human Molecular Genetics, 16:3017-3026, 2007
  360. M. Kamiyama, M. Kobayashi, S. Araki, A. Iida, T. Tsunoda, K. Kawai, M. Imanishi, M. Nomura, T. Babazono, Y. Iwamoto, A. Kashiwagi, K. Kaku, R. Kawamori, D.P.K. Ng, T. Hansen, P. Gaede, O. Pedersen, Y. Nakamura, and S. Maeda: Polymorphisms in the 3'UTR in the neurocalcin δ gene affect mRNA stability, and confer susceptibility to diabetic nephropathy. Human Genetics, 122:397-407, 2007

    2008　　↑ページトップへ

  361. N. Hosono, M. Kubo, Y. Tsuchiya, H. Sato, T. Kitamoto, S. Saito, Y. Ohnishi, and Y. Nakamura: Multiplex PCR-based real-time Invader assay (mPCR-RETINA): a novel SNP-based method for detecting allelic asymmetries within copy number variation regions. Human Mutation, 29:182-189, 2008
  362. Y. Onouchi, T. Gunji, J. C. Burns, C. Shimizu, J.W. Newburger, M. Yashiro, Yo. Nakamura, H.Yanagawa, K. Wakui, Y. Fukushima, F. Kishi, K. Hamamoto, M. Terai, Y. Sato, K. Ouchi, T. Saji, A. Nariai, Y. Kaburagi, T. Yoshikawa, K. Suzuki, T. Tanaka, T. Nagai, H. Cho, A. Fujino, A. Sekine, R. Nakamichi, T. Tsunoda, T. Kawasaki, Yu. Nakamura, and A. Hata: ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms. Nature Genetics, 40:35-42, 2008
  363. F. P. Silva, R. Hamamoto, M. Kunizaki, M. Tsuge, Y. Nakamura, and Y. Furukawa: Enhanced methyltransferase activity of SMYD3 by the cleavage of its N-terminal region in human cancer cells. Oncogene, 27:2686-2692, 2008
  364. K. Obama, S. Satoh, R. Hamamoto, Y. Sakai, Y. Nakamura, and Y. Furukawa: Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells. Clinical Cancer Research, 14:1333-1339, 2008
  365. M. Kato, F. Miya, Y. Kanemura, T. Tanaka, Y. Nakamura, and T. Tsunoda: Recombination rates of genes expressed in human tissues. Human Molecular Genetics, 17:577-586, 2008
  366. A. C. C. Leung,, V. C. L. Wong, L. C. Yang, P. L. Chan, Y. Daigo, Y. Nakamura, R. Z. Qi, L. Miller, E. T.-K. Liu, L. D. Wang, J.-L. Li, S. Law, S. W. Tsao, and M. L. Lung: Frequent decreased expression of candidate tumor suppressor gene, DEC1, and its anchorage-independent growth properties and impact on global gene expression in esophageal carcinoma. International Journal of Cancer, 122:587-594, 2008
  367. A. Shimo, C. Tanikawa, T. Nishidate, K. Matsuda, M.-L. Lin, J.-H. Park, T. Ohta, K. Hirata, M. Fukuda, Y. Nakamura, and T. Katagiri: Involvement of KIF2C/MCAK overexpression in mammary carcinogenesis. Cancer Science, 99:62-70, 2008
  368. M. Uemura, K. Tamura, S. Chung, S. Honma, A. Okuyama, Y. Nakamura, and H. Nakagawa: Novel 5α-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer. Cancer Science, 99:81-86, 2008
  369. Y. Kamatani, K. Matsuda, T. Ohishi, S. Ohtsubo, K. Yamazaki, A. Iida, N. Hosono, M. Kubo, W. Yumura, K. Nitta, T. Katagiri, Y. Kawaguchi, N. Kamatani, and Y. Nakamura: Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population. Journal of Human Genetics, 53:64-73, 2008
  370. C. Fukukawa, H. Hanaoka, S. Nagayama, T. Tsunoda, J. Toguchida, K. Endo, Y. Nakamura, and T. Katagiri: Radioimmunotherapy of human synovial sarcoma using a monoclonal antibody against FZD10. Cancer Science, 99:432-440, 2008
  371. J. Brunet, A. W. Pfaff, A. Abidi, M. Unoki, Y. Nakamura, M. Guinard, J.-P. Klein, E. Candolfi, and M. Mousli: Toxoplasma gondii exploits UHRF1 and induces host cell cycle arrest at G2 to enable its proliferation. Cellular Microbiology, 10:908-920, 2008
  372. N. Kato, T. Miyata, Y. Tabara, T. Katsuya, K. Yanai, H. Hanada, K. Kamide, J. Nakura, K. Kohara, F. Takeuchi, H. Mano, M. Yasunami, A. Kimura, Y. Kita, H. Ueshima, T. Nakayama, M. Soma, A. Hata, A. Fujioka, Y. Kawano, K. Nakao, A. Sekine, T. Yoshida, Y. Nakamura, T. Saruta, T. Ogihara, S. Sugano, T. Miki, and H. Tomoike: High-density association study and nomination of susceptibility genes for hypertension in the Japanese national project. Human Molecular Genetics, 17:617-627, 2008
  373. T. Oishi, A. Iida, S. Otsubo, Y. Kamatani, M. Usami, T. Takei, K. Uchida, K. Tsuchiya, S. Saito, Y. Ohnisi, K. Tokunaga, K. Nitta,Y. Kawaguchi, N. Kamatani, Y. Kochi, K. Shimane, K. Yamamoto, Y. Nakamura, W. Yumura, and K. Matsuda: A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to Systemic Lupus Erythematosus in Japanese population. Journal of Human Genetics, 53:151-162, 2008
  374. Y. Daigo, Y. Nakamura: From cancer genomics to thoracic oncology: discovery of new biomarkers and therapeutic targets for lung and esophageal carcinoma. (review article) General Thoracic and Cardiovascular Surgery, 56:43-53, 2008
  375. K. Kiyotani, T. Mushiroda, M. Kubo, H. Zembutsu, Y. Sugiyama, and Y. Nakamura: Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia. Cancer Science, 99:967-972, 2008
  376. K. Kiyotani, T. Mushiroda, M. Sasa, Y. Bando, I. Sumitomo, N. Hosono, M. Kubo, Y. Nakamura, and H. Zembutsu: Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy. Cancer Science, 99:995-999, 2008
  377. T. Kato, N. Sato, A. Takano, M. Miyamoto, H. Nishimura, E. Tsuchiya, S. Kondo, Y. Nakamura, and Y. Daigo: Activation of placenta-specific transcription factor distal-less homeobox 5 predicts clinical outcome in primary lung cancer patients. Clinical Cancer Research, 14:2363-2370, 2008
  378. A. Tenesa, S.M. Farrington, J.G.D. Prendergast, M.E. Porteous, M. Walker, N. Haq, R.A. Barnetson, E. Theodoratou, R. Cetnarskyj, N. Cartwright, R. Wilson, C. Semple, A.J. Clarke, F.J.L. Reid, L.A. Smith, K. Kavoussanakis, T. Kossler, P.D.P. Pharoah, S. Buch, C. Schafmayer, J. Tepel, S. Schreiber, H. Volzke, C.O. Schmidt, J. Hampe, S. Wilkening, F. Canzian, J. Chang-Claude, M. Hoffmeister, H. Brenner, G. Capella, V. Moreno, I.J. Deary, J.M. Starr, I.P.M. Tomlinson, E. Webb, R.S. Houlston, G. Rennert, D. Ballinger, L. Rozek, S.B. Gruber, K. Matsuda, T. Kidokoro, Y. Nakamura, B.W. Zanke, C.M.T. Greenwood, J. Rangrej, R. Kustra, A. Montpetit, T.J. Hudson, S. Gallinger, H. Campbell, and M.G. Dunlop: Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and resplicates risk loci at 8q24 and 18q21. Nature Genetics, 40:631-637, 2008
  379. H. Mototani, A. Iida, M. Nakajima, T. Furuichi, Y. Miyamoto, T. Tsunoda, A. Sudo, A. Kotani, A. Uchida, K. Ozaki, Y. Tanaka, Y. Nakamura, T. Tanaka, K. Notoya, and S. Ikegawa: A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese. Human Molecular Genetics, 17:1790-1797, 2008
  380. Y. Mizukami, K. Kono, Y. Daigo, A. Takano, T. Tsunoda, Y. Kawaguchi, Y. Nakamura, and H. Fujii: Detection of novel Cancer-Testis antigen-specific T-cell responses in TIL, regional lymph nodes and PBL in patients with esophageal squamous cell carcinoma. Cancer Science, 99:1448-1454, 2008
  381. T. Mushiroda, S. Wattanapokayakit, A. Takahashi, T. Nukiwa, S. Kudoh, T. Ogura, H. Taniguchi, Pirfenidone Clinical Study Group, M. Kubo, N. Kamatani, and Y. Nakamura: A genome-wide association study identifies an association of a common variant in TERT with susceptibility to idiopathic pulmonary fibrosis. Journal of Medical Genetics, 45:654-656, 2008
  382. M. Hosokawa, K. Kashiwaya, M. Furihara, H. Eguchi, H. Ohigashi, O. Ishikawa, Y. Shinomura, K. Imai, Y. Nakamura, and H. Nakagawa: Overexpression of cysteine proteinase inhibitor cystatin 6 promotes pancreatic cancer growth. Cancer Science, 99:1626-1632, 2008
  383. Study Group of Millennium Genome Project for Cancer, (H. Sakamoto, K. Yoshimura, N. Saeki, H. Katai, T. Shimoda, Y. Matsuno, D. Saito, H. Sugimura, F. Tanioka, S. Kato, N. Matsukura, N. Matsuda, T. Nakamura, I. Hyodo, T. Nishina, W. Yasui, H. Hirose, M. Hayashi, E. Toshiro, S. Ohnami, A. Sekine, Y. Sato, H. Totsuka, M. Ando, R. Takemura, Y. Takahashi, M. Ohdaira, K. Aoki, I. Honmyo, S. Chiku, K. Aoyagi, H. Sasaki, S. Ohnami, K. Yanagihara, K.-A. Yoon, M.-C. Kook, Y.-S. Lee, S. R. Park, C. G. Kim, I. J. Choi, T. Yoshida, Y. Nakamura, and S. Hirohashi): Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer. Nature Genetics, 40:730-740, 2008
  384. T. Ueki, T. Nishidate, J.H. Park, M.L. Lin, A. Shimo, K. Hirata, Y. Nakamura, and T. Katagiri: Involvement of elevated expression of multiple cell-cycle regulator, DTL/RAMP (denticleless /RA-regulated nuclear matrix associated protein), in the growth of breast cancer cells. Oncogene, 27:5672-5683, 2008
  385. Y. Miyamoto, D. Shi, M. Nakajima, K. Ozaki, A. Sudo, A. Kotani, A. Uchida, T. Tanaka, N. Fukui, T. Tsunoda, A. Takahashi, Y. Nakamura, Q. Jiang, and S. Ikegawa: Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis. Nature Genetics, 40:994-998, 2008
  386. H. Unoki, A. Takahashi, T. Kawaguchi, K. Hara, M. Horikoshi, G. Andersen, D.P.K. Ng, J. Holmkvist, K. Borch-Johnsen, T. J. Rgensen, A. Sandbaek, T. Lauritzen, T. Hansen, S. Nurbaya, T. Tsunoda, M. Kubo, T. Babazono, H. Hirose, M. Hayashi, Y. Iwamoto, A. Kashiwagi, K. Kaku, R. Kawamori, E. S. Tai, O. Pedersen, N. Kamatani, T. Kadowaki, R. Kikkawa, Y. Nakamura, and S. Maeda: SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nature Genetics, 40:1098-1102, 2008
  387. M. Harao , S. Hirata, A. Irie, S. Senju, T. Nakatsura, H. Komori, Y. Ikuta, K. Yokomine, K. Imai, M. Inoue, K. Harada, T. Mori, T. Tsunoda, S. Nakatsuru, Y. Daigo, H. Nomori, Y. Nakamura, H. Baba, and Y. Nishimura: HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL. International Journal of Cancer, 123:2616-2625, 2008
  388. K. Imai, S. Hirata, A. Irie, S. Senju, Y. Ikuta, K. Yokomine, M. Harao, M. Inoue, T. Tsunoda, S. Nakatsuru, H. Nakagawa, Y. Nakamura, H. Baba, and Y. Nishimura: Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric and colorectal cancers. Clinical Cancer Research, 14:6487-6495, 2008
  389. D.N. Nikolova, H. Zembutsu, T. Sechanov, K. Vidinov, L.S. Kee, R. Ivanova, E. Becheva, M. Kocova, D. Toncheva, and Y. Nakamura: Genome-wide gene expression profiles of thyroid carcinoma: Identification of molecular targets for treatment of thyroid carcinoma. Oncology Reports, 20:105-121, 2008
  390. Y. Nakamura:, Pharmacogenomics and drug toxicity. (Editorial) New Eng. J. Med., 359:856-858, 2008
  391. K. Arita, M. Ariyoshi, H. Tochio, Y. Nakamura, and M. Shirakawa: Recognition of hemi-methylated DNA by the SRA protein UHRF 1 by a base-flipping mechanism. Nature, 455:818-821, 2008
  392. H. Inoue, M. Iga, H. Nabeta, T. Yokoo, Y. Suehiro, S. Okano, M. Inoue, H. Kinoh, T. Katagiri, K. Takayama, Y. Yonemitsu, M. Hasegawa, Y. Nakamura, Y. Nakanishi, and K. Tani: Non-transmissible Sendai virus encoding GM-CSF is a novel and potent vector system to produce autologous tumor vaccines. Cancer Science, 99:2315-2326, 2008
  393. R. Konda, J. Sugimura, F. Sohma, T. Katagiri, Y. Nakamura, and T. Fujioka: Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1αand nuclear factor κB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure. The Journal of Urology, 180:481-485, 2008
  394. K. Hotta, Y. Nakata, T. Matsuo, S. Kamohara, K. Kotani, R. Komatsu, N. Itoh, I. Mineo, J. Wada, H. Masuzaki, M. Yoneda, A. Nakajima, S. Miyazaki, K. Tokunaga, M. Kawamoto, T. Funahashi, K. Hamaguchi, K. Yamada, T. Hanafusa, S. Oikawa, H. Yoshimatsu, K. Nakao, T. Sakata, Y. Matsuzawa, K. Tanaka, N. Kamatani, and Y. Nakamura: Variations in the FTO gene are associated with severe obesity in the Japanese. Journal of Human Genetics, 53:546-553, 2008
  395. M. Kato, Y. Nakamura, and T. Tsunoda: An algorithm for inferring complex haplotypes in a region of copy-number variation. Am. J. Human Genetics, 83:157-169, 2008
  396. M. Kato, Y. Nakamura, and T. Tsunoda: MOCSphaser: a haplotype inference tool from a mixture of copy number variation and single nucleotide polymorphism data. Bioinformatics, 24:1645-1646, 2008
  397. K. Yasuda, K. Miyake, Y. Horikawa, K. Hara, H. Osawa, H. Furuta, Y. Hirota, H. Mori, A. Jonsson, Y. Sato, K. Yamagata, Y. Hinokio, H.-Y. Wang, T. Tanahashi, N. Nakamura, Y. Oka, N. Iwasaki, Y. Iwamoto, Y. Yamada, Y. Seino, H. Maegawa, A. Kashiwagi, J. Takeda, E. Maeda, H. D. Shin, Y. M. Cho, K. S. Park, H. K. Lee, M. C. Y. Ng, R. C. W. Ma, W.-Y. So, J. C. N. Chan, V. Lyssenko, T. Tuomi, P.Nilsson, L. Groop, N. Kamatani, A. Sekine, Y. Nakamura, K. Yamamoto, T. Yoshida, K. Tokunaga, M. Itakura, H. Makino, K. Nanjo, T. Kadowaki, and M. Kasuga: Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nature Genetics, 40:1092-1097, 2008
  398. Y. Yamaguchi-Kabata, K. Nakazono, A. Takahashi, S. Saito, N. Hosono, M. Kubo, Y. Nakamura, and N. Kamatani: Japanese population structure, based on SNP genotypes from 7003 individuals compared to other ethnic groups: Effects on population-based association studies. Am. J. Human Genetics, 83:445-456, 2008
  399. Y. Okada, M. Mori, R. Yamada, A. Suzuki, K. Kobayashi, M. Kubo, Y. Nakamura, and K. Yamamoto: SLC22A4 polymorphism and rheumatoid arthritis susceptibility: A replication study in a Japanese population and a metaanalysis. The Journal of Rheumatology, 35:1723-1728, 2008
  400. S. Omori, Y. Tanaka, A. Takahashi, H. Hirose, A. Kashiwagi, K. Kaku, R. Kawamori, Y. Nakamura, and S. Maeda: Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility of type 2 diabetes in a Japanese population. Diabetes, 57:791-795, 2008
  401. K. Misawa, S. Fujii, T. Yamazaki, A. Takahashi, J. Takasaki, M. Yanagisawa, Y. Ohnishi, Y. Nakamura, and N. Kamatani: New correction algorithms for multiple comparisons in case-control multilocus association studies based on haplotypes and diplotype configurations. Journal of Human Genetics, 53:789-801, 2008
  402. A. Suzuki, R. Yamada, Y. Kochi, T. Sawada, Y. Okada, K. Matsuda, Y. Kamatani, M. Mori, K. Shimane, Y. Hirabayashi, A. Takahashi, T. Tsunoda, A. Miyatake, M. Kubo, N. Kamatani, Y. Nakamura, and K. Yamamoto: Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population. Nature Genetics, 40:1224-1229, 2008
  403. K. Hotta, M. Nakamura, Y. Nakata, T. Matsuo, S. Kamohara, K. Kotani, R. Komatsu, N. Itoh, I. Mineo, J. Wada, H. Masuzaki, M. Yoneda, A. Nakajima, S. Miyazaki, K. Tokunaga, M. Kawamoto T. Funahashi, K. Hamaguchi, K. Yamada, T. Hanafusa, S. Oikawa, H. Yoshimatsu, K. Nakao, T. Sakata, Y. Matsuzawa, K. Tanaka, N. Kamatani, and Y. Nakamura: INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese. Journal of Human Genetics, 53:857-862, 2008
  404. K. Iwahori, T. Osaki, S. Serada, M. Fujimoto, H. Suzuki, Y. Kishi, A. Yokoyama, H. Hamada, Y. Fujii, K. Yamaguchi, T. Hirashima, K. Matsui, I. Tachibana, Y. Nakamura, I. Kawase, and T. Naka: Megakaryocyte potentiating factor as a tumor maker of malignant pleural mesothelioma: Evaluation in comparison with mesothelin. Lung Cancer, 62:45-54, 2008
  405. T. Hirota, M. Harada, M. Sakashita, S. Doi, A. Miyatake, K. Fujita, T. Enomoto, M. Ebisawa, S. Yoshihara, E. Noguchi, H. Saito, Y. Nakamura, and M. Tamari: Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population. J Allergy Clin Immunol, 121:769-770, 2008
  406. M. Sakashita, T. Yoshimoto, T. Hirota, M. Harada, K. Ohkubo, Y. Osawa, S. Fujieda, Y. Nakamura, K. Yasuda, K. Nakanishi, and M. Tamari: Association of serum IL-33 level and the IL-33 genetic variant with Japanese cedar pollinosis. Clin Exp Allergy, 38:1875-1881, 2008

    2009↑ページトップへ

  407. M. Harada, T. Hirota, A.I. Jodo, S. Doi, M. Kameda, K. Fujita, A. Miyatake, T. Enomoto, E. Noguchi, S. Yoshihara, M. Ebisawa, H. Saito, K. Matsumoto, Y. Nakamura, S.F. Ziegler, and M.Tamari: Functional analysis of the Thymic Stromal Lymphopoietin Variants in Human Bronchial Epithelial Cells. Am J Respir Cell Mol Biol, 40:368-374, 2009
  408. S. Chantarangsu , T. Mushiroda, S. Mahasirimongkol, S. Kiertiburanakul, S. Sungkanuparph, W. Manosuthi, W. Tantisiriwat, A. Charoenyingwattana, T. Sura, W. Chantratita, and Y. Nakamura: HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in Thai HIV-infected patients. Pharmacogenetics and Genomics, 19:139-146, 2009
  409. D. N. Nikolova, N. Doganov, R. Dimitrov, K. Angelov, S.-K. Low, I. Dimova, D. Toncheva, Y. Nakamura, and H. Zembutsu: Genome-wide gene expression profiles of ovarian carcinoma: identification of molecular targets for the treatment of ovarian carcinoma. Molecular Medicine Reports, 2:365-384, 2009
  410. K. Yamazaki, A. Takahashi, M Takazoe, M. Kubo, Y. Onouchi, A. Fujino, N. Kamatani, Y. Nakamura, and A. Hata: Positive association of genetic variants in the upstream region of NXT2-3 with Crohn's disease in Japanese patients. Gut, 58:228-232, 2009
  411. D. Hirata, T. Yamabuki, D. Miki, T. Ito, E. Tsuchiya, M. Fujita, M. Hosokawa, K. Chayama, Y. Nakamura, and Y. Daigo: Involvement of epithelial cell transforming sequence-2 oncoantigen in lung and esophageal cancer progression. Clinical Cancer Research, 15:256-266, 2009
  412. S. Dobashi, T. Katagiri, E. Hirota, S. Ashida, Y. Daigo, T. Shuin, T. Fujioka, T. Miki, and Y. Nakamura: Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells. Oncology Reports, 21:305-312, 2009
  413. H. Zembutsu, Y. Suzuki, A. Sasaki, T. Tsunoda, M. Okazaki, M. Yoshimoto, T. Hasegawa, K. Hirata, and Y. Nakamura: Predicting response to Docetaxel neoadjuvant chemotherapy for advanced breast cancers through genome-wide gene expression profiling. International Journal of Oncology, 34:361-370, 2009
  414. Y. Nakamura: DNA variations in human and medical genetics: 25 years of my experience. (review) Journal of Human Genetics, 54:1-8, 2009
  415. K. Ozaki, H. Sato, K. Inoue, T. Tsunoda, Y. Sakata, H. Mizuno, T.-H. Lin, Y. Miyamoto, A. Aoki, Y. Onouchi, S.-H. Sheu, S. Ikegawa, K. Odashiro, M. Nobuyoshi, S.-H. H. Juo, M. Hori, Y. Nakamura, and T. Tanaka: SNPs in BRAP associated with risk of myocardial infarction in Asian populations. Nature Genetics, 41:329-333, 2009
  416. K. Kashiwaya, M. Hosokawa, H. Eguchi, H. Ohigashi, O. Ishikawa, Y. Shinomura, Y. Nakamura, and H. Nakagawa: Identification of C2orf18, Termed ANT2BP (ANT2-binding protein), as one of key molecules involved in pancreatic carcinogenesis. Cancer Science, 100:457-464, 2009
  417. S. Nagayama, E. Yamada, Y. Kohno, T. Aoyama, C. Fukukawa, H. Kubo, G. Watanabe, T. Katagiri, Y. Nakamura, Y. Sakai, and J. Toguchida: Inverse correlation of the upregulation of FZD10 expression and the activation of β-catenin in synchronous colorectal tumors. Cancer Science, 100:405-412, 2009
  418. K. Ueda, Y. Fukase, T. Katagiri, N. Ishikawa, S. Irie, T. Sato, H. Ito, H. Nakayama, Y. Miyagi, E. Tsuchiya, N. Kohno, M. Shiwa, Y. Nakamura, and Y. Daigo: Targeted serum glycoproteomics for the discovery of lung cancer-associated glycosylation disorders using lectin-coupled ProteinChip arrays. Proteomocs, 9:2182-2192, 2009
  419. The International Warfarin Pharmacogenetics Consortium:, Estimation o the warfarin dose with clinical and pharmacogenetic data. New Eng. J. Med., 360:753-764, 2009
  420. E.T. Betcheva, T. Mushiroda, A. Takahashi, M. Kubo, S.K. Karachanak, I.T. Zaharieva, R.V. Vazharova, I.I. Dimova, V.K. Milanova, T. Tolev, G. Kirov, M.J. Owen, M.C. O'Donovan, N. Kamatani, Y. Nakamura, and D.I. Toncheva: Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population. Journal of Human Genetics, 54:98-107, 2009
  421. C. Fukukawa, S. Nagayama, T. Tsunoda, J. Toguchida, Y. Nakamura, and T. Katagiri: Activation of the non-canonical Dvl-Rac1-JNK pathway by Frizzled homologue 10 in human synovial sarcoma. Oncogene, 28:1110-1120, 2009
  422. A. Yosifova, T. Mushiroda, D. Stoianov, R. Vazharova, I. Dimova, S. Karachanak, I. Zaharieva, V. Milanova, N. Madjirova, I. Gerdjikov, T. Tolev, S. Velkova, G. Kirov, M. J. Owen, M. C. O’Donovan, D. Toncheva, and Y. Nakamura: Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. Journal of Affective Disorders, 117:87-97, 2009
  423. Y. Kamatani, S. Wattanapokayakit, H. Ochi, T. Kawaguchi, A. Takahashi, N. Hosono, M. Kubo, T. Tsunoda, N. Kamatani, H. Kumada, A. Puseenam, T. Sura, Y. Daigo, K. Chayama, W. Chantratita, Y. Nakamura, and K. Matsuda: A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians. Nature Genetics, 41:591-595, 2009
  424. K. Tamura, M. Furihata, S. Chung,　M. Uemura, H. Yoshioka, T. Iiyama, S. Ashida, Y. Nasu, T. Fujioka, T. Shuin, Y. Nakamura, and H. Nakagawa: Stanniocalcin 2 (STC2) over-expression in castration-resistant prostate cancer and aggressive prostate cancer. Cancer Science, 100:914-919, 2009
  425. H. Tsukada, H. Ochi, T. Maekawa, H. Abe, Y. Fujimoto, M. Tsuge, H. Takahashi, H. Kumada, N. Kamatani, Y. Nakamura, and K. Chayama: A Polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C. Gastroenterology, 136:1796-1805, 2009
  426. E. M. Dunleavy, D. Roche, H. Tagami, N. Lacoste, D. Ray-Gallet, Y. Nakamura, Y. Daigo, Y. Nakatani, and G. Almouzni-Pettinotti: HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres. Cell, 137:485-497, 2009
  427. M.-L. Lin, C. Fukukawa, J.-H. Park, K. Naito, K. Kijima, M. Ajiro, A. Shimo, T. Nishidate, Y. Nakamura, and T. Katagiri: Involvement of G-patch domain containing 2 overexpression in breast carcinogenesis. Cancer Science, 100:1443-1450, 2009
  428. K. Morioka, C. Tanikawa, K. Ochi, Y. Daigo, T. Katagiri, H. Kawano, H. Kawaguchi, A. Myoui, H. Yoshikawa, N. Naka, N. Araki, I. Kudawara, M. Ieguchi, K. Nakamura, Y. Nakamura, and K. Matsuda: Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma. Cancer Science, 100:1227-1233, 2009
  429. K. Asano, T. Matsushita, J. Umeno, N. Hosono, A. Takahashi, T. Kawaguchi, T. Matsumoto, T. Matsui, Y. Kakuta, Y. Kinouchi, T. Shimosegawa, M. Hosokawa, Y. Arimura, Y. Shinomura, Y. Kiyohara, T. Tsunoda, N. Kamatani, M. Iida, Y. Nakamura, and M. Kubo: A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. Nature Genetics, 41:1325-1331, 2009
  430. S. Chung, M. Furihata, K. Tamura, M. Uemura, Y. Daigo, Y. Nasu, T. Miki, T. Shuin, T. Fujioka, Y. Nakamura, and H.　Nakagawa: Overexpressing PKIB in prostate cancer promotes its aggressiveness by linking between PKA and Akt pathways. Oncogene, 28:2849-2859, 2009
  431. C. C. Ng, P. Y. Yew, S. M. Puah, G. Krishnan, L. F. Yap, S. H. Teo, P. V. H. Lim, S. Govindaraju, K. Ratnavelu, C. K. Sam, A. Takahashi, M. Kubo, N. Kamatani, Y. Nakamura, and T. Mushiroda: A genome-wide association study identifies ITGA9 conferring risk of nasopharyngeal carcinoma. Journal of Human Genetics, 54:392-397, 2009
  432. J.-W. Kim, M. Akiyama, J.-H. Park, M.-L. Lin, A. Shimo, T. Ueki, T. Nishidate, Y. Nakamura, and T. Katagiri: Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer. Cancer Science, 100:1468-1478, 2009
  433. M. Unoki, J. D. Kelly, D. E. Neal, B.A.J. Ponder, Y. Nakamura, and R. Hamamoto: UHRF1 is a novel molecular marker for diagnosis and the prognosis of bladder cancer. British Journal of Cancer, 101:98-105, 2009
  434. C. Tanikawa, Y. Furukawa, N. Yoshida, H. Arakawa, Y. Nakamura, and K. Matsuda: XEDAR as a putative colorectal tumor suppressor that mediates p53-regulated anoikis pathway. Oncogene, 28:3081-3092, 2009
  435. K. Hotta, T. Nakamura, J. Takasaki, H. Takahashi, A. Takahashi, Y. Nakata, S. Kamohara, K. Kotani, R. Komatsu, N. Itoh, I. Mineo, J. Wada, H. Masuzaki, M. Yoneda, A. Nakajima, T. Funahashi, S. Miyazaki, K. Tokunaga, K. Hamaguchi, K. Tanaka, K. Yamada, T. Hanafusa, S. Oikawa, H. Yoshimatsu, K. Nakao, T. Sakata, Y. Matsuzawa, N. Kamatani, and Y. Nakamura: Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome. Journal of Human Genetics, 54:230-235, 2009
  436. K. Kono, Y. Mizukami, Y. Daigo, A. Takano, K. Masuda, K. Yoshida, T. Tsunoda, Y. Kawaguchi, Y. Nakamura, and H. Fujii: Vaccination with multiple peptides derived from novel cancer-testis antigens can induce specific T-cell responses and clinical responses in advanced esophageal cancer. Cancer Science, 100:1502-1509, 2009
  437. N. Hosono, M. Kato, K. Kiyotani,　T. Mushiroda, S. Takata, H. Sato, H. Amitan, Y. Tsuchiya, K. Yamazaki, T. Tsunoda, H. Zenbutsu, Y. Nakamura, and M. Kubo: CYP2D6 genotyping for functional-gene dosage analysis by allele copy number detection. Clinical Chemistry, 55:1546-1554, 2009
  438. A. Takano, N. Ishikawa, R. Nishino, K. Masuda, W. Yasui, K. Inai, H. Nishimura, H. Ito, H. Nakayama, Y. Miyagi, E. Tsuchiya, N. Kohno, Y. Nakamura, and Y. Daigo: Identification of Nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer. Cancer Research, 69:6694-6703, 2009
  439. H. Abe, H. Ochi, T. Maekawa, T. Hatakeyama, M. Tsuge, S. Kitamura, T. Kimura, D. Miki, F. Mitsui, N. Hiraga, M. Imamura, Y. Fujimoto, S. Takahashi, Y. Nakamura, H. Kumada, and K. Chayama: Effects of structural variations of APOBEC3A and APOBEC3B genes in chronic hepatitis B virus infection. Hepatology Research, 39:1159-1168, 2009
  440. K. Moriwaki, K. Noda, Y. Furukawa, K. Ohshima, A. Uchiyama, T. Nakagawa, N. Taniguchi, Y. Daigo, Y. Nakamura, N. Hayashi, and E. Miyoshi: Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling. Gastroenterology, 137:188-198, 2009
  441. S. Chung, K. Tamura, M. Furihata, M. Uemura, Y. Daigo, Y. Nasu, T. Miki, T. Shuin, T. Fujioka, Y. Nakamura, and H. Nakagawa: Overexpression of the potential kinase, Serine/Threonine/Tyrosine Kinase 1(STYK1 ) in castration-resistant prostate cancer. Cancer Science, 100:2109-2114, 2009
  442. S.-K. Low, K. Kiyotani, T. Mushiroda, Y. Daigo, Y. Nakamura, and H. Zembutsu: Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients. Journal of Human Genetics, 54:564-571, 2009
  443. P.-C. Cha, T. Mushiroda, H. Zembutsu, H. Harada, N. Shinoda, S. Kawamoto, R. Shimoyama, T Nishidate, T. Furuhata, K. Sasaki, K. Hirata, and Y. Nakamura: Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression. Journal of Human Genetics, 54:572-580, 2009
  444. M. Ajiro, T. Katagiri, K. Ueda, H. Nakagawa, C. Fukukawa, M.-L. Lin, J.-H. Park, T. Nishidate, Y. Daigo, and Y. Nakamura: Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells. International Journal of Oncology, 35:673-681, 2009
  445. Y. Okada, R. Yamada, A. Suzuki, Y. Kochi, K. Shimane, K. Myouzen, M. Kubo, Y. Nakamura, and K. Yamamoto: Contribution of a Haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1. Arthritis & Rheumatism, 60:3582-3590, 2009
  446. R. Cui, Y. Kamatani, A. Takahashi, M. Usami, N. Hosono, T. Kawaguchi, T. Tsunoda, N. Kamatani, M. Kubo, Y. Nakamura, and K. Matsuda: Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. Gastroenterology, 137:1768-1775, 2009
  447. K. Tamura, A. Makino, F. Hullin-Masuda, T. Kobayashi, M. Furihata, S. Chung, S. Ashida, T. Miki, T. Fujioka, T. Shuin, Y. Nakamura, and H. Nakagawa: Novel lipogenic enzyme ELOVL7 involves in prostate cancer growth through saturated long-chain fatty acid metabolism. Cancer Research, 69:8133-8140, 2009
  448. T. Ueki, J.-H. Park, T. Nishidate, K. Kijima, K. Hirata, Y. Nakamura, and T. Katagiri: Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells. Cancer Research, 69:8752-8760, 2009
  449. H. Nakahara, N. Hosono, T. Kitayama, K. Sekiguchi, M. Kubo, A. Takahashi, Y. Nakamura, Y. Yamano, and K. Kai: Automated SNPs typing system based on the Invader assay. Legal Medicine, 11 Suppl1:S111-114, 2009
  450. C. Tanikawa, K. Ueda, H. Nakagawa, N. Yoshida, Y. Nakamura, and K. Matsuda: Regulation of protein citrullination through p53/PADI4 network in DNA damage response. Cancer Research, 69:8761-8769, 2009
  451. M. Kato, T. Kawaguchi, S. Ishikawa, T. Umeda, R. Nakamichi, M. H. Shapero, K. W. Jones, Y. Nakamura, H. Aburatani, and T. Tsunoda: Population-genetic nature of copy number variations in the human genome. Human Molecular Genetics, 19:761-773, 2009
  452. S. Omori, Y. Tanaka, M. Horikoshi, A. Takahashi, K. Hara, H. Hirose, A. Kashiwagi, K. Kaku, R. Kawamori, T. Kadowaki, Y. Nakamura, and S. Maeda: Replication study for the association of new meta-analysis-derived risk loci with susceptibility to type 2 diabetes in 6,244 Japanese individuals. Diabetologia, 52:1554-1560, 2009
  453. T. Matsushita, M. Kubo, K.Yonemoto, T. Ninomiya, K. Ashikawa, B. Liang, J. Hata, Y. Doi, T. Kitazono, S. Ibayashi, M. Iida, Y. Kiyoharam and Y. Nakamura: Lack of association between variations of PDE4D and ischemic stroke in the Japanese population. Stroke, 40:1245-1251, 2009
  454. K. Shimane, Y. Kochi, R. Yamada, Y. Okada, A. Suzuki, A. Miyake, M. Kubo, Y. Nakamura, and K. Yamamoto: A single nucleotide polymorphism in the IRF5 promoter region is associated with susseptibility to rheumatoid arthritis in the Japanese patients. Annals of the Rheumatic Diseases, 68:377-383, 2009
  455. M. Tamari, M. Harada, T. Hirota, and Y. Nakamura: Host molecular defence mechanisms against Chlamydophilia pneumoniae and genetic studies of immune-response-related genes in asthma. Recent Pat Inflamm Allergy Drug Discovory, 3:17-25, 2009
  456. M. Harada, K. Obara, T. Hirota, T. Yoshimoto, Y. Hitomi, M. Sakashita, S. Doi, A. Miyatake, K. Fujita, T. Enomoto, M. Taniguchi, N. Higashi, Y. Fukutomi, K. Nakanishi, Y. Nakamura, and M. Tamari: A functional polymorphism in IL-18 is associated with severity of bronchimal asthma. Am J Respir Crit Care Med, 180:1048-1055, 2009
  457. Y. Hitomi, M. Ebisawa, M. Tomikawa, T. Imai, T. Kamata, T. Hirota, M. Harada, M. Sakashita, Y. Suzuki, N. Shomojo, Y. Kohno, K. Fujita, A. Miyatake, S. Doi, T. Enomoto, M. Taniguchi, N. Higashi, Y. Nakamura, and M. Tamari: Association of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma. Journal of Allergy and Clinical Immunology, 124:779-785, 2009
  458. H. Naruse, N. Ikawa, K. Yamaguchi, Y. Nakamura, M. Arai, C. Ishioka, K. Sugano, K. Tamura, N. Tomita, N. Matsubara, T. Yoshida, Y. Moriya, and Y. Furukawa: Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay. Familial Cancer, 8:509-517, 2009
  459. H. Eguchi, O. Ishikawa, H. Ohigashi, H. Takahashi, M. Yano, K. Nishiyama, Y. Tomita, R. Uehara, A. Takehara, Y. Nakamura, and H. Nakagawa: Serum REG4 level is a predictive biomarker for the response to preoperative chemoradiotherapy in patients with pancreatic cancer. Pancreas, 38:791-798, 2009
  460. K. Hotta, M. Nakamura, T. Nakamura, T. Matuso, Y. Nakata, S. Kamohara, N. Miyatake, K. Kotani, R. Komatsu, N. Itoh, I. Mineo, J. Wada, H. Masuzaki, M. Yoneda, A. Nakajima, T. Funahashi, S. Miyazaki, K. Tokunaga, M. Kawamoto, T. Ueno, K. Hamaguchi, K. Tanaka, K. Yamada, T. Hanafusa, S. Oikawa, H. Yoshimatsu, K. Nakao, T. Sakata, Y. Matsuzawa, N. Kamatani, and Y. Nakamura: Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population. Journal of Human Genetics, 54:727-731, 2009
  461. T. Nagao, M. Kira, M. Takahashi, J. Honda, T. Hirose, A. Tangoku, H. Zembutsu, Y. Nakamura, and M. Sasa: Serum estradiol should be monitored not only during the peri-menopausal period but also the post-menopausal period at the time of aromatase inhibitor administration. World Journal of Surgical Oncology, 7:88-92, 2009
  462. W. Satake, Y. Nakabayashi, I. Mizuta, Y. Hirota, C. Ito, M. Kubo, T. Kawaguchi, T. Tsunoda, M. Watanabe, A. Takeda, H. Tomiyama, K. Nakashima, K. Hasegawa, F. Obata, T. Yoshikawa, H. Kawakami, S. Sakoda, M. Yamamoto, N. Hattori, M. Murata, Y. Nakamura, and T. Toda: Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nature Genetics, 41:1303-1307, 2009

    2010↑ページトップへ

  463. K. Nishimoto, Y. Kochi, K. Ikari, K. Yamamoto, A. Suzuki, K. Shimane, Y. Nakamura, K. Yano, N. Iikuni, S. Tsukahara, N. Kamatani, H. Okamoto, H. Kaneko, Y. Kawaguchi, M. Hara, Y. Toyama, T. Horiuchi, K. Tao, K. Yasumoto, D. Hamada, N. Yasui, H. Inoue, M. Itakura, H. Yamanaka, and S. Momohara: Association study of TRAF1-C5 polymorphisms with susceptibility to　rheumatoid arthritis and systemic lupus erythematosus in Japanese. Annals of the Rheumatic Diseases, 69:368-373, 2010
  464. K. Kiyotani, T. Mushiroda, C. K. Imamura, N. Hosono, T. Tsunoda, M. Kubo, Y. Tanigawara, D.A. Flockhart, Z. Desta, T.C. Skaar, F. Aki, K. Hirata, Y. Takatsuka, M. Okazaki, S. Ohsumi, T. Yamakawa, M. Sasa, Y. Nakamura, and H. Zembutsu: Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients. J. Clin. Oncology, 28:1287-1293, 2010
  465. N. Sato, J. Koinuma, M. Fujita, M. Hosokawa, T. Ito, E. Tsuchiya, S. Kondo, Y. Nakamura, and Y. Daigo: Activation of WD repeat and High-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis. Clinical Cancer Research, 16:226-239, 2010
  466. W. Wangsomboonsiri, S. Mahasirimongkol, S. Chantarangsu, S. Kiertiburanakul, A. Charoenyingwattana, S. Komindr, C. Thongnak, T. Mushiroda, Y. Nakamura, W. Chantratita, and S. Sungkanuparph: Association between HLA-B*4001 and lipodystrophy among HIV-infected patients from Thailand who received a stavudine-containing antiretroviral regimen. Clinical Infectious Diseases, 50597-604, 2010
  467. M. Miyazawa, R. Ohsawa, T. Tsunoda, S. Hirono, M. Kawai, M. Tani, Y. Nakamura, and H. Yamaue: Phase I clinical trial using peptide vaccine for human vascular endothelial growth factor receptor 2 in combination with gemcitabine for patients with advanced pancreatic cancer. Cancer Science, 101433-439, 2010
  468. M. Nuinoon, W. Makarasara, T. Mushiroda, I. Setianingsih, P. A. Wahidiyat, O. Sripichai, N. Kumasaka, A. Takahashi, S. Svasti, T. Munkongdee, S. Mahasirimongkol, C. Peerapittayamongkol, V. Viprakasit, N. Kamatani, P. Winichagoon, M. Kubo, Y. Nakamura, and S. Fucharoen: A genome-wide association identified the common genetic variants influence disease severity in β0-thalassemia/hemoglobin E. Human Genetics, 127303-314, 2010
  469. H. Nakahara, K. Sekiguchi, N. Hosono, M. Kubo, A. Takahashi, Y. Nakamura, and K. Kasai: Criterion values for multiplex SNP genotyping by the Invader assay. Forensic Science International: Genetics, 4130-136, 2010
  470. J.-H. Park, T. Nishidate, Y. Nakamura, and T. Katagiri: Critical roles of T-LAK cell-originated protein kinase in cytokinesis. Cancer Science, 101403-411, 2010
  471. N. Sato, J. Koinuma, T. Ito, E. Tsuchiya, S. Kondo, Y. Nakamura, and Y. Daogo: Activation of an oncogenic TBC1D7 (TBC1 Domain Family, Member 7) protein in pulmonary carcinogenesis. Genes Chromosomes and Cancer, 49353-367, 2010
  472. Y. Kamatani, K. Matsuda, M. Kubo, N. Hosono, Y. Daigo, Y. Nakamura, and N. Kamatani: Genome-wide association study of hematological and biochemical traits in a Japanise population. Nature Genetics, 42210-215, 2010
  473. M. Inoue, S. Senju, S. Hirata, Y. Ikuta, Y. Hayashida, A. Irie, M. Harao, K. Imai, Y. Tomita, T. Tsunoda, Y. Furukawa, T. Ito, Y. Nakamura, H. Baba, and Y. Nishimura: Identification of SPARC as a candidate target antigen for immunotherapy of various cancers. Int. J. Cancer, 1271393-1403, 2010
  474. S. Maeda, M. Kobayashi, S. Araki, T. Babazono, B. I. Freedman, M. A. Bostrom, J. N. Cooke, M. Toyoda, T. Umezono, L. Tarnow, T. Hansen, P. Gaede, A. Jorsal, D. P K Ng, M. Ikeda, T. Yanagimoto, T. Tsunoda, H. Unoki, K. Kawai, M. Imanishi, D. Suzuki, H. D. Shin, K. S. Park, A. Kashiwagi, Y. Iwamoto, K. Kaku, R. Kawamori, H.-H. Parving, D. W. Bowden, O. Pedersen, and Y. Nakamura: A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 Diabetes. PLoS Genetics, 6e1000842, 2010
  475. J.-H. Park, T. Nishidate, K. Kijima, T. Ohashi, K. Takegawa, T. Fujikane, K. Hirata, Y. Nakamura, and T. Katagiri: Critical roles of mucin1 glycosylation by transactivated polypeptide N-acetylgalactosaminyltransferase 6 in mammary carcinogenesis. Cancer Research, 702759-2769, 2010
  476. H. Mototani, A. Iida, Y. Nakamura, and S. Ikegawa: Identification of sequence polymorphisms in CALM2 and analysis of association with hip osteoarthritis in a Japanese population. Journal of Bone and Mineral Metabolism, 28547-553, 2010
  477. N.J. Prescott, K.M. Dominy, M. Kubo, C.M. Lewis, S.A. Fisher, R. Redon, N. Huang, B.E. Stranger, K. Blaszczyk, B. Hudspith, G. Parkes, N. Hosono, K. Yamazaki, C.M. Onnie, A. Forbes, E.T. Dermitzakis, Y. Nakamura, J.C. Mansfield, J. Sanderson, M.E. Hurles, R.G. Roberts, and C.G. Mathew: Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease. Human Molecular Genetics, 191828-1839, 2010
  478. S. Hayami, M. Yoshimatsu, A. Veerakumarasivam, M. Unoki, Y. Iwai, T. Tsunoda, H.I. Field, J.D. Kelly, D.E. Neal, H. Yamaue, B.A.J. Ponder, Y. Nakamura, and R. Hamamoto: Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway. Molecular Cancer, 959-73, 2010
  479. R. Takayama, H. Nakagawa, A. Sawaki, N. Mizuno, H. Kawai, M. Tajika, Y. Yatabe, K. Matsuo, R. Uehara, K. Ono, Y. Nakamura, and K. Yamao: Serum tumor antigen REG4 a diagnostic biomarker in pancreatic ductal adenocarcinoma. Journal of Gastroenterol, 45:52-59, 2010
  480. K. Yasuno, K. Bilguvar, P. Bijlenga, S.-K. Low, B. Krischek, G. Auburger, M. Simon, D. Krex, Z. Arlier, N. Nayak, Y.M. Ruigrok, M. Niemela, A. Tajima, M. Fraunberg, T. Doczi, F. Wirjatijasa, A. Hata, J. Blasco, A. Oszvald, H. Kasuya, G. Zilani, B. Schoch, P. Singh, C. Stuer, R. Risselada, J. Beck, S. Teresa, F. Ricciardi, A. Aromaa, T. Illig, S. Schreiber, C.M. van Duijn, L.H. van den Berg, C. Perret, C. Proust, C. Roder, A.K. Ozturk, E. Gaal, D. Berg, C. Geisen, C.M. Friedrich, P. Summers, A.F. Frangi, M.W. State, H.E. Wichmann, M.M.B. Breteler, C. Wijmenga, S. Mane, L. Peltonen, V. Elio, M.CJM. Sturkenboom, P. Lawford, J. Byrne, J. Macho, I.E. Sandalcioglu, B. Meyer, A. Raabe, D. Rufenacht, J.E. Jaaskelainen, J. Hernesniemi, G.J.E. Rinkel, H. Zembutsu, I. Inoue, A. Palotie, F. Cambien, Y. Nakamura, R.P. Lifton, and M. Gunel: Genome-wide association study of intracranial aneurysm identifies three new risk loci. Nature Genetics, 42:420-425, 2010
  481. M. Nakajima, A. Takahashi, I. Kou, C. Rodriguez-Fontenla, J.J. Gomez-Reino, T. Furuichi, J. Dai, A. Sudo, A. Uchida, N. Fukui, M. Kubo, N. Kamatani, T. Tsunoda, K.N. Malizos, A. Tsezou, A. Gonzalez, Y. Nakamura, and S. Ikegawa: New sequence variants in HLA class Ⅱ/Ⅲ region associated with susceptibility to knee osteoarthritis identified by genome-wide association study. PLoS ONE, 5:e9723, 2010
  482. S. Hayami, J. D. Kelly, H.-S. Cho, M. Yoshimatsu, M. Unoki, T. Tsunoda, H.I. Field, D.E. Neal, H. Yamaue, B.A.J. Ponder, Y. Nakamura, and R. Hamamoto: Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers. Int. J. Cancer, 128574-586, 2010
  483. The International Cancer Genome Consortium:, International network of cancer genome projects. Nature, 464993-998, 2010
  484. K. Yamaguchi, M. Sakai, T. Shimokawa, Y. Yamada, Y. Nakamura, and Y. Furukawa: C20orf20 (MRG-binding protein) as a potential therapeutic target for colorectal cancer. British Journal of Cancer, 102325-331, 2010
  485. K. Kashiwaya, H. Nakagawa, M. Hosokawa, Y. Mochizuki, L. Piao, S. Chung, K. Ueda, R. Hamamoto, H. Eguchi, H. Ohigashi, O. Ishikawa, C. Janke, Y. Shinomura, and Y. Nakamura: Involvement of tublin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells. Cancer Research, 704024-4033, 2010
  486. N. Akuta, F. Suzuki, M. Hirakawa, Y. Kawamura, H. Yatsuji, H. Sezaki, Y. Suzuki, T. Hosaka, M. Kobayashi, M. Kobayashi, S. Saitoh, Y. Arase, K. Ikeda, K. Chayama, Y. Nakamura, and H. Kumada: Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin. Hepatology, 52421-429, 2010
  487. N. Phasukkijwatana, B. Kunhapan, J. Stankovich, W. L. Chuenkongkaew, R. Thomson, T. Thornton, M. Bahlo, T. Mushiroda, Y. Nakamura, S. Mahasirimongkol, A. W. Tun, C. Srisawat, C. Limwongse, C. Peerapittayamongkol, T. Sura, W. Suthammarak, and P. Lertrit: Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand. Human Genetics, 12839-49, 2010
  488. A. Ramamoorthy, D. A. Flockharta, N. Hosono, M. Kubo, Y. Nakamura, and T. C. Skaar: Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assays. Pharmacogenetics and Genomics, 20451-454, 2010
  489. Y. Kochi, Y. Okada, A. Suzuki, K. Ikari, C. Terao, A. Takahashi, K. Yamazaki, N. Hosono, K. Myouzen, T. Tsunoda, N. Kamatani, T. Furuichi, S. Ikegawa, K. Ohmura, T. Mimori, F. Matsuda, T. Iwamoto, S. Momohara, H. Yamanaka, R. Yamada, M. Kubo, Y. Nakamura, and K. Yamamoto: A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility. Nature Genetics, 42515-519, 2010
  490. K. Kiyotani, T. Mushiroda, N. Hosono, T. Tsunoda, M. Kubo, F. Aki, Y. Okazaki, K. Hirata, Y. Takatsuka, M. Okazaki, S. Ohsumi, T. Yamakawa, M. Sasa, Y. Nakamura, and H. Zembutsu: Lessons for pharmacogenomics studies; association study between CYP2D6 genotype and tamoxifen response. Pharmacogenetics and Genomics, 20565-568, 2010
  491. H. Abe, H. Ochi, T. Maekawa. C.N. Hayes, M. Tsuge. D. Miki, F. Mitsui, N. Hiraga, M. Imamura, S. Takahashi, W. Ohishi, K. Arihiro, M. Kubo, Y. Nakamura, and K. Chayama: Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients. J. Hepatology, 53:439-443, 2010
  492. C. Tanikawa, Y. Nakamura, and K. Matsuda: Crosstalk of EDA-A2/XEDAR in the p53 signaling pathway. Molecular Cancer Research, 8855-863, 2010
  493. Y. Onouchi, K. Ozaki, J.C. Buns, C. Shimizu, H. Hamada, T. Honda, M. Terai, A. Honda, T. Takeuchi, S. Shibuta, T. Suenaga, H. Suzuki, K. Higashi, K. Yasukawa, Y. Suzuki, K. Sasago, Y. Kemmotsu, S. Takatsuki, T. Saji, T. Yoshikawa, T. Nagai, K. Hamamoto, F. Kishi, K. Ouchi, Y. Sato, J. W. Newburger, A. L. Baker, S. T. Shulman, A. H. Rowley, M. Yashiro, Y. Nakamura, K. Wakui, Y. Fukushima, A. Fujino, T. Tsunoda, T. Kawasaki, A. Hata, Y. Nakamura, and T. Tanaka: Common variants in CASP3 confer susceptibility to Kawasaki disease. Human Molecular Genetics, 192898-2906, 2010
  494. K. Yokomine, S. Senju, T. Nakatsura, A. Irie, Y. Hayashida, Y. Ikuta, M. Harao, K. Imai, H. Baba, H. Iwase, H. Nomori, K. Takahashi, Y. Daigo, T. Tsunoda, Y. Nakamura, Y. Sasaki, and Y. Nishimura: The forkhead box M1 transcription factor as a candidate of target for anti-cancer immunotherapy. Int. J. Cancer, 1262153-2163, 2010
  495. M.-H. Nguyen, J. Koinuma, K. Ueda, T. Ito, E. Tsuchiya, Y. Nakamura, and Y. Daigo: Phosphorylation and activation of cell division cycle associated 5 by mitogen-activated protein kinase play a crucial role in human lung carcinogenesis. Cancer Research, 705337-5347, 2010
  496. C. Fukukawa, K. Ueda, T. Nishidate, T. Katagiri, and Y. Nakamura: Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells. Genes Chromosomes and Cancer, 49861-872, 2010
  497. N. Sato, T. Yamabuki, A. Takano, J. Koinuma, M. Aragaki, K. Masuda, N. Ishikawa, N. Kohno, H. Ito, M. Miyamoto, H. Nakayama, Y. Miyagi, E. Tsuchiya, S. Kondo, Y. Nakamura, and Y. Daigo: Wnt Inhibitor dickkopf-1 as a target for passive cancer immunotherapy. Cancer Research, 705326-5336, 2010
  498. Y. Harada, M. Kanehira, Y. Fujisawa, R. Takata, T. Shuin, T. Miki, T. Fujioka, Y. Nakamura, and T. Katagiri: Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells. Cancer Research, 705829-5839, 2010
  499. S. Uno, H. Zembutsu, A. Hirasawa, A. Takahashi, M. Kubo, T. Akahane, D. Aoki, N. Kamatani, K. Hirata, and Y. Nakamura: A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese. Nature Genetics, 42707-710, 2010
  500. M. Uemura, S. Honma, S. Chung, R. Takata, M. Furihata, K. Nishimura, N. Nonomura, Y. Nasu, T. Miki, T. Shuin, T. Fujioka, A. Okuyama, Y. Nakamura, and H. Nakagawa: 5αDH-DOC (5α-dihydro-deoxycorticosterone) activates androgen receptor in castration-resistant prostate cancer. Cancer Science, 1011897-1904, 2010
  501. H. Akaza, K. Kawai, T. Tsukamoto, T. Fujioka, Y. Tomita, T. Kitamura, S. Ozono, T. Miki, S. Naito, H. Zembutsu, and Y. Nakamura: Successful outcomes using combination therapy of interleukin-2 and interferon-α for renal cell carcinoma patients with lung metastasis. Jpn. J. Clin. Oncol., 40684-689, 2010
  502. K. Ueda, S. Takami, N. Saichi, Y. Daigo, N. Ishikawa, N. Kohno, M. Katsumata, A. Yamane, M. Ota, T.-A. Sato, Y. Nakamura, and H. Nakagawa: Development of serum glycoproteomic profiling technique; simultaneous identification of glycosylation sites and site-specific quantification of glycan structure changes. Molecular and Cellular Proteomics, 91819-1828, 2010
  503. J.N. Ingle, D.J. Schaid, P.E. Goss, M. Liu, T. Mushiroda, J.-A.W. Chapman, M. Kubo, G.D. Jenkins, A. Batzler, L. Shepherd, J. Pater, L. Wang, M.J. Ellis, V. Stearns, D.C. Rohrer, M.P. Goetz, K.I. Pritchard, D.A. Flockhart, Y. Nakamura, and R.M. Weinshilboum: Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors. J. Clin. Oncology, 284674-4682, 2010
  504. Y. Okada, Y. Kamatani, A. Takahashi, K. Matsuda, N. Hosono, H. Ohmiya, Y. Daigo, K. Yamamoto, M. Kubo, Y. Nakamura, and N. Kamatani: Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count. Human Molecular Genetics, 192079-2085, 2010
  505. Y. Okada, Y. Kamatani, A. Takahashi, K. Matsuda, N. Hosono, H. Ohmiya, Y. Daigo, K. Yamamoto, M. Kubo, Y. Nakamura, and N. Kamantani: A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci. Human Molecular Genetics, 19:2303-2312, 2010
  506. R. Takata, S. Akamatsu, M. Kubo, A. Takahashi, N. Hosono, T. Kawaguchi, T. Tsunoda, J. Inazawa, N. Kamatani, O. Ogawa, T. Fujioka, Y. Nakamura, and H. Nakagawa: Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population. Nature Genetics, 42:751-754, 2010
  507. J.-W. Kim, C. Fukukawa, K. Ueda, T. Nishidate, T. Katagiri, and Y. Nakamura: Involvement of C12orf32 overexpression in breast carcinogenesis. International Journal of Oncology, 37861-867, 2010
  508. M. Nakashima, S. Chung, A. Takahashi, N. Kamatani, T. Kawaguchi, T. Tsunoda, N. Hosono, M. Kubo, Y. Nakamura, and H. Zembutsu: A genome-wide association study identifies four susceptibility loci for keloid in Japanese population. Nature Genetics, 42768-771, 2010
  509. A. Iida, T. Kamei, M. Sano, S. Oshima, T. Tokuda, Y. Nakamura, and S. Ikegawa: Large-scale screening of TARDBP mutations in amyotrophic lateral sclerosis in Japanese. Neurobiology of Aging, Jul 30. [Epub ahead of print], 2010
  510. S.-K. Low, A. Kuchiba, H. Zembutsu, A. Saito, A. Takahashi, M. Kubo, Y. Daigo, N. Kamatani, S. Chiku, H. Totsuka, S. Ohnami, H. Hirose, K. Shimada, T. Okusaki, T. Yoshida, Y. Nakamura, and H. Sakamoto: Genome-wide association study of pancreatic cancer in Japanese population. PLoS ONE, 5e11824, 2010
  511. H. Ochi, T. Maekawa, H. Abe, Y. Hayashida, R. Nakano, M. Kubo, T. Tsunoda, C.N. Hayes, H. Kumada, Y. Nakamura, and K. Chayama: ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy - a genome-wide study of Japanese HCV virus patients. Gastroenterology, 139:1190-1197, 2010
  512. O. Mizumori, H. Zembutsu, Y. Kato, T. Tsunoda, F. Miya, T. Morizono, T. Tsukamoto, T. Fujioka, Y. Tomita, T. Kitamura, S. Ozono, T. Miki, S. Naito, H. Akaza, and Y. Nakamura: Identification of a set of genes associated with response to interleukin-2 and interferon-α combination therapy for renal cell carcinoma through genome-wide gene expression profiling. Experimental and Therapeutic Medicine, 1955-961, 2010
  513. M. Ajiro, T. Nishidate, T. Katagiri, and Y. Nakamura: Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis. International Journal of Oncology, 371085-1093, 2010
  514. D. Miki, M. Kubo, A. Takahashi, K.-A. Yoon, J. Kim, G.-K. Lee, J.I. Zo, J.S. Lee, N. Hosono, T. Morizono, T. Tsunoda, N. Kamatani, K. Chayama, T. Takahashi, J. Inazawa, Y. Nakamura, and Y. Daigo: Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean population. Nature Genetics, 42893-896, 2010
  515. K. Myouzen, Y. Kochi, K. Shimane, K. Fujio, T. Okamura, Y. Okada, A. Suzuki, T. Atsumi, S. Ito, K. Takada, A. Mimori, S. Ikegawa, R. Yamada, Y. Nakamura, and K. Yamamoto: Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus. Human Molecular Genetics, 192313-2320, 2010
  516. T. Yamauchi, K. Hara, S. Maeda, K. Yasuda, A. Takahashi, M. Horikoshi, M. Nakamura, H. Fujita, N. Grarup, S Cauchi, D. Ng, R. Ma, T. Tsunoda, M. Kubo, H. Watada, H. Maegawa, M. Okada-Iwabu, M. Iwabu, N. Shojima, H.D. Shin, G. Andersen, D.R. Witte, T. Jorgensen, T. Lauritzen, A. Sandbaek, T. Hansen, T. Ohshige, S. Omori, I. Saito, K. Kaku, H. Hirose, W.-Y. So, D. Beury, J. Chan, K.S. Park , S. Tai , C. Ito, Y. Tanaka, A. Kashiwagi, R. Kawamori, M. Kasuga, P. Froguel, O. Pedersen, N. Kamatani, Y. Nakamura, and T. Kadowaki: A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B. Nature Genetics, 42864-868, 2010
  517. S. Akamatsu, R. Takata, K. Ashikawa, N. Hosono, N. Kamatani, T. Fujioka, O Ogawa, M. Kubo, Y. Nakamura, and H. Nakagawa: A functional variant in NKX3.1 associated with prostate cancer susceptibility down-regulates NKX3.1 expression. Human Molecular Genetics, 19:4265-4272, 2010
  518. Y. Okada, A. Suzuki, R. Yamada, Y. Kochi, K. Shimane, K. Myouzen, M. Kubo, Y. Nakamura, and K. Yamamoto: HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 69:1569-1570, 2010
  519. P.-C. Cha, T. Mushiroda, A. Takahashi, M. Kubo, S. Minami, N. Kamatani, and Y. Nakamura: Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese. Human Molecular Genetics, 194735-4744, 2010
  520. S. Maeda, S. Araki, T. Babazono, M. Toyoda, T. Umezono, K. Kawai, M. Imanishi, T. Uzu, H. Watada, D. Suzuki, A. Kashiwagi, Y. Iwamoto, K. Kaku, R. Kawamori, and Y. Nakamura: Replication study for the association between four loci identified by a genome-wide association study on European American subjects with type 1 diabetes and susceptibility to diabetic nephropathy in Japanese subjects with type 2 diabetes. Diabetes, 592075-2079, 2010
  521. N. Kumasaka , Y. Yamaguchi-Kabata, A. Takahashi, M. Kubo, Y. Nakamura, and N. Kamatani: Establishment of a standardized system to perform population structure analyses with limited sample size or with different sets of SNP genotypes. Journal of Human Genetics, 55525-533, 2010
  522. N. Stefanou, V. Papanikolaou, Y. Furukawa, Y. Nakamura, and A. Tsezou: Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase. BMC Cancer, 10:442, 2010
  523. Y. Yamaguchi-Kabata, T. Tsunoda, A. Takahashi, N. Hosono, M. Kubo, Y. Nakamura, and N. Kamatani: Making a haplotype catalog with estimated frequencies based on SNP homozygotes. Journal of Human Genetics, 55:500-506, 2010
  524. A. Fujimoto, H. Nakagawa, N. Hosono, K. Nakano, T. Abe, K.A. Boroevich, M. Nagasaki, R. Yamaguchi, T. Shibuya, M. Kubo, S. Miyano, Y. Nakamura, and T. Tsunoda: Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing. Nature Genetics, 42931-936, 2010
  525. K.-A. Yoon, J.H. Park, J. Han, S. Park, G.K. Lee, J.-Y. Han, J.I. Zo, J. Kim, J.E. Lee, A. Takahashi, M. Kubo, Y. Nakamura, and J.S. Lee: A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population. Human Molecular Genetics, 194948-4954, 2010
  526. O.L.J. Peerbooms, J. van Os, M. Drukker, G. Kenis, L. Hoogveld, MTHFR in Psychiatry Group, M. de Hert, P. Delespaul, R. van Winkel, and B.P.F. Rutten: Meta-analysis of MTHFR gene variants in schizophrenia, bipolar disorder and unipolar depressive disorder: evidence for a common genetic vulnerability? Brain, Behavior, and Immunity, Dec 24. [Epub ahead of print], 2010
  527. T. Matsushita, K. Ashikawa, K. Yonemoto, Y. Hirakawa, J. Hata, H. Amitani, Y. Doi, T. Ninomiya, T. Kitazono, S. Ibayashi, M. Iida, Y. Nakamura, Y. Kiyohara, and M. Kubo: Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke. Human Molecular Genetics, 19:1137-1146, 2010
  528. T. Matsushita, J. Umeno, Y. Hirakawa, K. Yonemoto, K. Ashikawa, H. Amitani, T, Ninomiya, J. Hata, Y. Doi, T. Kitazono, M. Iida, Y. Nakamura, Y. Kiyohara, and M. Kubo: Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population. Journal of Human Genetics, 55:473-476, 2010
  529. I.P.M. Tomlinson, M. Dunlop, H. Campbell, B. Zanke, S. Gallinger, T. Hudson, T. Koessler, P.D. Pharoah, I. Niittyma¨kix, S. Tuupanenx, L.A. Aaltonen, K. Hemminki, A. Lindblom, A. Fo¨ rsti, O. Sieber, L. Lipton, T. van Wezel, H. Morreau, J.T. Wijnen, P. Devilee, K. Matsuda, Y. Nakamura, S. Castellvı´-Bel, C. Ruiz-Ponte, A. Castells, A. Carracedo, J.W.C. Ho, P. Sham, R.M.W. Hofstra, P. Vodicka, H. Brenner, J. Hampe, C. Schafmayer, J. Tepel, S. Schreiber, H. Vo¨ lzke, M.M. Lerch, C.A. Schmidt, S. Buch, V. Moreno, C.M. Villanueva, P. Peterlongo, P. Radice, M.M. Echeverry, A. Velez, L. Carvajal-Carmona, R. Scott, S. Penegar, P. Broderick, A. Tenesa, and R.S. Houlston: COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer. British Journal of Cancer, 102:447-454, 2010

    2011↑ページトップへ

  530. H.-S. Cho, T. Suzuki, N. Dohmae, S. Hayami, M. Unoki, M. Yoshimatsu, G. Toyokowa, M. Takawa, T. Chen, J. K. Kurash, H.I. Field, B.A.J. Ponder, Y. Nakamura, and R. Hamamoto: Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells. Cancer Research, 71:655-660, 2011
  531. R. Cui, Y. Okada, S.G. Jang, J.L. Ku, J.G. Park, Y. Kamatani, N. Hosono, T. Tsunoda, V. Kumar, C. Tanikawa, N. Kamatani, R. Yamada, M. Kubo, Y. Nakamura, and K. Matsuda: Common variant in 6q26-q27 is associated with distal colon cancer in Asian population. Gut, 60:799-805, 2011
  532. K. Imai, S. Hirata, A. Irie, S. Senju, Y. Ikuta, K. Yokomine, M. Harao, M. Inoue, Y. Tomita, T. Tsunoda, H. Nakagawa, Y. Nakamura, H. Baba, and Y. Nishimura: Identification of HLA-A2-restricted CTL epitopes of a novel tumor-associated antigen, KIF20A, overexpressed in pancreatic cancer. British Journal of Cancer, 104:300-307, 2011
  533. A. Iida, N. Hosono, M. Sano, T. Kamei, S. Oshima, T. Tokuda, M. Kubo, Y. Nakamura, and S. Ikegawa: Optineurin mutations in Japanese amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery & Psychiatry, Jan 8. [Epub ahead of print]:, 2011
  534. T. Ozeki, T. Mushiroda, A. Yowang, A. Takahashi, M. Kubo, Y. Shirakata, Z. Ikezawa, M. Iijima, T. Shiohara, K. Hashimoto, N. Kamatani, and Y. Nakamura: Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population. Human Molecular Genetics, 20:1034-1041, 2011
  535. Y. Fujimoto , H. Ochi, T. Maekawa, H. Abe, C.N. Hayes, H. Kumada, Y. Nakamura, and K. Chayama: A single nucleotide polymorphism in activated cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients. J. Hepatology, 54:629-639, 2011
  536. Y. Hashimoto, H. Ochi, H. Abe, Y. Hayashida, M. Tsuge, F. Mitsui, N. Hiraga, M. Imamura, S. Takahashi, C.N. Hayes, W. Ohishi, M. Kubo, T. Tsunoda, N. Kamatani, Y. Nakamura, and K. Chayama: Prediction of response to peginterferon-alfa-2b plus ribavirin therapy in Japanese patients infected with hepatitis C virus genotype 1b. J. Med. Virol., 83:981-988, 2011
  537. F. Suzuki, Y. Suzuki, N. Akuta, H. Sezaki, M. Hirakawa, Y. Kawamura, T. Hosaka, M. Kobayashi, S. Saito, Y. Arase, K. Ikeda, M. Kobayashi, K. Chayama, N. Kamatani, Y. Nakamura, Y. Miyakawa, and H. Kumada: Influence of ITPA polymorphism on decreases of hemoglobin during treatment with pegylated IFN, ribavirin and telaprevir. Hepatology, 53:415-421, 2011
  538. T. Kawaoka , C.N. Hayes, W. Ohishi, H. Ochi, T. Maekawa, H. Abe, M. Tsuge, F. Mitsui, N. Hiraga, M. Imamura, S. Tkakahashi, M. Kubo, T. Tsunoda, Y. Nakamura, H. Kumada, and K. Chayama: Predictive value of IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b. J. Hepatology, 54:408-414, 2011
  539. A. Aoki, K. Ozaki, H. Sato, A. Takahashi, M. Kubo, Y. Sakata, Y. Onouchi, T. Kawaguchi, T.-H. Lin, H. Takano, M. Yasutake, P.-C. Hsu, S. Ikegawa, N. Kamatani, T. Tsunoda, S.-H. H. Juo, M. Hori, I. Komuro, K. Mizuno, Y. Nakamura, and T. Tanaka: SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population. Journal of Human Genetics, 56:47-51, 2011
  540. M. Yoshimatsu, G. Toyokawa, S. Hayami, M. Unoki, T. Tsunoda, H.I. Field, J.D. Kelly, D.E. Neal, Y. Maehara, B.A.J. Ponder, Y. Nakamura, and R. Hamamoto: Dysregulation of PRMT1 and PRMT6, type I arginine methyltransferases, is involved in various types of human cancers. Int. J. Cancer, 128:562-573, 2011
  541. C.N. Hayes, M. Kobayashi, N. Akuta, F. Suzuki, H. Kumada, H. Abe, D. Miki, M. Imamura, H. Ochi, N. Kamatani, Y. Nakamura, and K. Chayama: HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy. Gut, 60:261-267, 2011
  542. P. Saetre, M. Vares, T. Werge, O.A. Andreassen, T. Arinami, H. Ishiguro, S. Nanko, E.C. Tan, D. H. Han, J. Roffman, J.-W. Muntjewerff, P.P. Jagodzinski, B. Kempisty, J. Hauser, E. Vilella, E. Betcheva, Y. Nakamura, B. Regland, I. Agartz, H. Hall, L. Terenius, and E.G. Jönsson: Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: a combined analysis of independent samples. Neuropsychiatric Genetics, Jan 13. [Epub ahead of print]:, 2011
  543. S. Chung, H. Nakagawa, M. Uemura, L. Piao, K. Ashikawa, N. Hosono, R. Takata, S. Akamatsu, T. Kawaguchi, T. Morizono, T. Tsunoda, Y. Daigo, K. Matsuda, N. Kamatani, Y. Nakamura, and M. Kubo: Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility. Cancer Science, 102:245-252, 2011
  544. L. Piao, H. Nakagawa, K. Ueda, S. Chung, K. Kashiwaya, H. Eguchi, H. Ohigashi, O. Ishikawa, Y. Daigo, K. Matsuda, and Y. Nakamura: C12orf48, termed PARP-1 binding protein (PARPBP), enhances poly (ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage. Genes Chromosomes and Cancer, 50:13-24, 2011
  545. A. Iida, A. Takahashi, M. Deng, Y. Zhang, J. Wang, N. Atsuta, F. Tanaka, T. Kamei, M. Sano, S. Oshima, T. Tokuda, M. Morita, C. Akimoto, M. Nakajima, M. Kubo, N. Kamatani, I. Nakano, G. Sobue, Y. Nakamura, D. Fan, and S. Ikegawa: Replication analysis of SNPs on 9p21.2 and 19p13.3 with amyotrophic lateral sclerosis in East Asians. Neurobiology of Aging, 32:757.e13-14, 2011
  546. Y. Tomita, K. Imai, S. Senju, A. Irie, M. Inoue, Y. Hayashida, K. Shiraishi, T. Mori, Y. Daigo, T. Tsunoda, T. Ito, H. Nomori, Y. Nakamura, H. Kohrogi, and Y. Nishimura: A novel tumor-associated antigen, cell division cycle 45-like can induce cytotoxic T lymphocytes reactive to tumor cells. Cancer Science, 102:697-705, 2011
  547. J.-H. Park, T. Katagiri, S. Chung, K. Kijima, and Y. Nakamura: Polypeptide N-acetylgalactosaminyltransferase 6 (GALNT6) disrupts mammary acinar morphogenesis through O-glycosylation of fibronectin. Neoplasia, 13:320-326, 2011
  548. Y. Kato, H. Zembutsu, R. Takata, F. Miya, T. Tsunoda, W. Obara, T. Fujioka, and Y. Nakamura: Predicting response of bladder cancers to gemcitabine and carboplatin neoadjuvant chemotherapy through genome-wide gene expression profiling. Experimental and Therapeutic Medicine, 2:47-56, 2011
  549. H. Zembutsu, M. Sasa, K. Kiyotani, T. Mushiroda, and Y. Nakamura: Should CYP2D6 inhibitors be administered in conjunction with tamoxifen? Expert Review of Anticancer Therapy, 11:185-193, 2011
  550. S. Maeda, D. Koya, S. Araki, T. Babazono, T. Umezono, M. Toyoda, K. Kawai, M. Imanishi, T. Uzu, D. Suzuki, H. Maegawa, A. Kashiwagi, Y. Iwamoto, and Y. Nakamura: Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes. Clinical Experimental Nephrology, 15:381-390, 2011
  551. K. Okamoto, K. Tokunaga, K. Doi, T. Fujita, H. Suzuki, T. Katoh, T. Watanabe, N. Nishida, A. Mabuchi, A. Takahashi, M. Kubo, S. Maeda, Y. Nakamura, and E. Noiri: Common variation in GPC5 is associated with acquired nephrotic syndrome. Nature Genetics, 43:459-463, 2011
  552. T.A. Johnson, Y. Niimura, H. Tanaka, Y. Nakamura, and T. Tsunoda: hzAnalyzer: Detection, quantification, and visualization of contiguous homozygosity in high-density genotyping datasets. Genome Biology, 12:R21[Epub ahead of print], 2011
  553. K.G. Tantisira, J. Lasky-Su, M. Harada, A. Murphy, A.A. Litonjua, B.E. Himes, C. Lange, R. Lazarus, J. Sylvia, B. Klanderman, Q.L. Duan, W. Qiu, T. Hirota, F.D. Martinez, D. Mauger, C. Sorkness, S. Szefler, S.C. Lazarus, R.F. Lemanske Jr, S.P. Peters, J.J. Lima, Y. Nakamura, M. Tamari, and S.T. Weiss: Genome-wide association of GLCCI1 with asthma steroid treatment response. New Eng. J. Med., 365:1173-1183, 2011
  554. V. Kumar, N. Kato, K. Urabe, A. Takahashi, R. Muroyama, N. Hosono, M. Otsuka, R. Tateishi, M. Omata, H. Nakagawa, K. Koike, N. Kamatani, M. Kubo, Y. Nakamura, and K. Matsuda: Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma. Nature Genetics, 43:455-458, 2011
  555. P.-C. Cha, A. Takahashi, N. Hosono, S.-K. Low, N. Kamatani, M. Kubo, and Y. Nakamura: A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids. Nature Genetics, 43:447-450, 2011
  556. F. Nyberg, B.J. Barratt, T. Mushiroda, A. Takahashi, A. Jawaid, S. Hada, T. Umemura, M. Fukuoka, K. Nakata, Y. Ohe, H. Kato, S. Kudoh, R. March, Y. Nakamura, and N. Kamatani: Interstitial lung disease in gefitinib-treated Japanese patients with non-small-cell lung cancer: genome-wide analysis of genetic data. Pharmacogenomics , 12:965-975, 2011
  557. V. Kumar, K. Matsuo, A. Takahashi, N. Hosono, T. Tsunoda, N. Kamatani, S.-Y. Kong, H. Nakagawa, R. Cui, C. Tanikawa, M. Seto, Y. Morishima, M. Kubo, Y. Nakamura, and K. Matsuda: Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility. Journal of Human Genetics, 56:436-439, 2011
  558. Y. Okada, T. Hirota, Y. Kamatani, A. Takahashi, H. Ohmiya, N. Kumasaka, K. Higasa, Y. Yamaguchi-Kabata, N. Hosono, M.A. Nalls, M.H. Chen, F.J.A. van Rooij, A.V. Smith, T. Tanaka, D.J. Couper, N.A. Zakai, L. Ferrucci, D.L. Longo, D.G. Hernandez, J.C.M. Witteman, T.B. Harris, C.J. O'Donnell, S.K. Ganesh, K. Matsuda, T. Tsunoda, T. Tanaka, M. Kubo, Y. Nakamura, M. Tamari, K. Yamamoto, and N. Kamatani: Identification of nine novel loci associated with white blood cell subtypes in a Japanese population. PLoS Genetics, 7:e1002067, 2011
  559. K. Ueda, N. Saichi, S. Takami, D. Kang, A. Toyama, Y. Daigo, N. Ishikawa, N. Kohno, K. Tamura, T. Shuin, A. Yamane, M. Ota, T. Sato, Y. Nakamura, and H. Nakagawa: A comprehensive peptidome profiling technology for the identification of early detection biomarkers for lung adenocarcinoma. PLoS ONE, 6:e18567, 2011
  560. A. Toyama, H. Nakagawa, K. Matsuda, N. Ishikawa, N. Kohno, Y. Daigo, T. Sato, Y. Nakamura, and K. Ueda: Deglycosylation and label-free quantitative LC-MALDI MS applied to efficient serum biomarker discovery of lung cancer. Proteome Science, 9:18, 2011
  561. M. Takawa, K. Masuda, M. Kunizaki, Y. Daigo, K. Takagi, Y. Iwai, H.-S. Cho, G. Toyokawa, Y. Yamane, K. Maejima, H.I. Field, T. Kobayashi, T. Akasu, M. Sugiyama, E. Tsuchiya, Y. Atomi, B.A.J. Ponder, Y. Nakamura, and R. Hamamoto: Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker. Cancer Science, 102:1298-1305, 2011
  562. I. Kou, A. Takahashi, T. Urano, N. Fukui, H. Ito, K. Ozaki, T. Tanaka, T, Hosoi, M. Shiraki, S. Inoue, Y. Nakamura, N. Kamatani, M. Kubo, S. Mori, and S. Ikegawa: Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese. PLoS ONE, 6:e19641, 2011
  563. M.A. Nalls, D.J. Couper, T. Tanaka, F.J.A. van Rooij, M-H. Chen, A.V. Smith, D. Toniolo, N.A. Zakai, Q. Yang, A. Greinacher, A.R. Wood, M. Garcia, P. Gasparini, Y. Liu, T. Lumley, A.R. Folsom, A.P. Reiner, C. Gieger, V. Lagou, J.F. Felix, H. Völzke, N.A. Gouskova, A. Biffi, A. Döring, U. Völker, S. Chong, K.L. Wiggins, A. Rendon, A. Dehghan, M. Moore, K. Taylor, J.G. Wilson, G. Lettre, A. Hofman, J.C. Bis, N. Pirastu, C.S. Fox, C. Meisinger, J. Sambrook, S. Arepalli, M. Nauck, H. Prokisch, J. Stephens, N.L. Glazer, L.A. Cupples, Y. Okada, A. Takahashi, Y. Kamatani, K. Matsuda, T. Tsunoda, T. Tanaka, M. Kubo, Y. Nakamura, K. Yamamoto, N. Kamatani, M. Stumvoll, A. Tönjes, I. Prokopenko, T. Illig, K.V. Patel, S.F. Garner, B. Kuhnel, M. Mangino, B.A. Oostra, S.L. Thein, J. Coresh, H.-E. Wichmann, S. Menzel, J. Lin, G. Pistis, A.G. Uitterlinden, T.D. Spector, A. Teumer, G. Eriksdottir, V. Gudnason, S. Bandinelli, T. Frayling, A. Chakravarti, C.M. van Duijn, D. Melzer, W.H. Ouwehand, D. Levy, E. Boerwinkle, A.B. Singleton, D.G. Hernandez, D.L. Longo, N. Soranzo, J.C.M. Witteman, B.M. Psaty, L. Ferrucci, T.B. Harris, C.J. O'Donnell, and S.K. Ganesh: Multiple loci are associated with white blood cell phenotypes. PLoS Genetics, 7:e1002113, 2011
  564. C. Terao, R. Yamada, K. Ohmura, M. Takahashi, T. Kawaguchi, Y. Kochi, Human Disease Genomics Working Group, RA Clinical and Genetic Study Consortium, Y. Okada, Y. Nakamura, K. Yamamoto, I. Melchers, M. Lathrop, T. Mimori, and F. Matsuda: The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population. Human Molecular Genetics, 20:2680-2685, 2011
  565. K. Chayama, C.N. Hayes, H. Abe, D. Miki, H. Ochi, Y. Karino, J. Toyota, Y. Nakamura, N. Kamatani, H. Sezaki, M. Kobayashi, N. Akuta, F. Suzuki, and H. Kumada: IL28B but not ITPA polymorphism is predictive of response to peg-interferon, ribavirin and telaprevir triple therapy in patients with genotype 1 hepatitis C. Journal of Infectious Diseases, 204:84-93, 2011
  566. T. Azakami, C.N. Hayes, H. Sezaki, M. Kobayashi, N. Akuta, F. Suzuki, H. Kumada, H. Abe, D. Miki, M. Tsuge, M. Imamura, Y. Kawakami, S. Takahashi, H. Ochi, Y. Nakamura, N. Kamatani, and K. Chayama: Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy. J. Med. Virol., 83:1048-1057, 2011
  567. H. Ochi , T. Maekawa, H. Abe, Y. Hayashida, R. Nakano, M. Imamura, N. Hiraga, Y. Kawakami, S. Aimitsu, J.-H. Kao, M. Kubo, T. Tsunoda, H. Kumada, Y. Nakamura, C.N. Hayes, and K. Chayama: IL-28B predicts response to chronic hepatitis C therapy - fine-mapping and replication study in Asian populations. Journal or General Virology, 92:1071-1081, 2011
  568. T. Mushiroda, Y. Nakamura: Personalizing carbamazepine therapy (Review). Genomic Medicine, 3:28, 2011
  569. S. Chantarangsu, T. Mushiroda, S. Mahasirimongkol, S. Kiertiburanakul, S. Sungkanuparph, W. Manosuthi, W. Tantisiriwat, A. Charoenyingwattana, T. Sura, A. Takahashi, M. Kubo, N. Kamatani, W. Chantratita, and Y. Nakamura: Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash. Clinical Infectious Diseases, 53:341-348, 2011
  570. G. Toyokawa, K. Masuda, Y. Daigo, H.-S. Cho, M. Yoshimatsu, M. Takawa, S. Hayami, K. Maejima, M. Chino, H.I. Field, D.E. Neal, E. Tsuchiya, B.A.J. Ponder, Y. Maehara, Y. Nakamura, and R. Hamamoto: Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer. Molecular Cancer, 10:65, 2011
  571. Y. Srinivasan, M. Sasa, J. Honda, A. Takahashi, S. Uno, N. Kamatani, M. Kubo, Y. Nakamura. and H. Zembutsu: Genome-wide association study of epirubicin-induced leukopenia in Japanese patients. Pharmacogenetics and Genomics, 21:552-558, 2011
  572. H.-S. Cho, J. D. Kelly, S. Hayami, G. Toyokawa, M. Takawa, M. Yoshimatsu, T. Tsunoda, H. I. Field, D. E. Neal, B. A.J. Ponder, Y. Nakamura, and R. Hamamoto: Enhanced expression of EHMT2 is involved in the proliferation of cancer cells through negative regulation of SIAH1. Neoplasia, 13:678-684, 2011
  573. T. Tanabe, N. Yamaguchi, K. Matsuda, K. Yamazaki, S. Takahashi, A. Tojo, M. Onizuka, Y. Eishi, H. Akiyama, J. Ishikawa, T. Mori, M. Hara, K. Koike, K. Kawa, T. Kawase, Y. Morishima, H. Amano, M. Kobayashi-Miura, T. Kakamu, Y. Nakamura, S. Asano, and Y. Fujita: Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population. International Journal of Hematology, :DOI 10.1007/s12185-011-0860-5, 2011
  574. D. Miki, H. Ochi, C.N. Hayes, H. Abe, T. Yoshima, H. Aikata, K. Ikeda,H. Kumada, J. Toyota, T. Morizono, T. Tsunoda, M. Kubo, Y. Nakamura, N. Kamatani, and K. Chayama: Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers. Nature Genetics, 43:797-800, 2011
  575. T. Hirota, A. Takahashi, M. Kubo, T. Tsunoda, K. Tomita, S. Doi, K. Fujita, A. Miyatake, T. Enomoto, T. Miyagawa, M. Adachi, H. Tanaka, A. Niimi, H. Matsumoto, I. Ito, H. Masuko, T. Sakamoto, N. Hizawa, M. Taniguchi, J.J. Lima, C.G. Irvin, S.P. Peters, B.E. Himes, A.A. Litonjua, K.G. Tantisira, S.T. Weiss, N. Kamatani, Y. Nakamura, and M. Tamari: Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. Nature Genetics, 43:893-896, 2011
  576. S. Arakawa, A. Takahashi, K. Ashikawa, N. Hosono, T. Aoi, M. Yasuda, Y. Oshima, S. Yoshida, H. Enaida, T. Tsuchihashi, K. Mori, S. Honda, A. Negi, A. Arakawa, K. Kadonosono, Y. Kiyohara, N. Kamatani, Y. Nakamura, T. Ishibashi, and M. Kubo: Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population. Nature Genetics, 43:1001-1004, 2011
  577. A.P. Reiner, G. Lettre, M.A. Nalls, S.K. Ganesh, R. Mathias, M.A. Austin, E. Dean, S. Arepalli, A. Britton, Z. Chen, D. Couper, J.D. Curb, C.B. Eaton, M. Fornage, S.F.A. Grant, T.B. Harris, D. Hernandez, N. Kamatani, B.J. Keating, M. Kubo, A. LaCroix, L.A. Lange, S. Liu, K. Lohman, Y. Meng, E.R. Mohler Ⅲ, S. Musani, Y. Nakamura, C.J. O'Donnell, Y. Okada, C.D. Palmer, G.J. Papanicolaou, K.V. Patel, A.B. Singleton, A. Takahashi, H. Tang, H.A. Taylor Jr., K. Taylor, C. Thomson, L.R. Yanek, L. Yang, E. Ziv, A.B. Zonderman, A.R. Folsom, M.K. Evans, Y. Liu, D.M. Becker, B.M. Snively, and J.G. Wilson: Genome-wide association study of white blood cell count in 16,388 African Americans: the Continental Origins and Genetic Epidemiology Network (COGENT). PLoS Genetics, 7:e1002108, 2011
  578. Y. Okada, A. Takahashi, H. Ohmiya, N. Kumasaka, Y. kamatani, N. Hosono, T. Tsunoda, K. Matsuda, T. Tanaka, M. Kubo, Y. Nakamura, K. Yamamoto, and N. Kamatani: Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus. Human Molecular Genetics, 20:1224-1231, 2011
  579. A. Iida, A. Takahashi, M. Kubo, S. Saito, N. Hosono, Y. Ohnishi, K. Kiyotani, T. Mushiroda, M. Nakajima, K. Ozaki, T. Tanaka, T. Tsunoda, S. Oshima, M. Sano, T. Kamei, T. Tokuda, M. Aoki, K. Hasegawa, K. Mizoguchi, M. Morita , Y. Takahashi, M. Katsuno, N. Atsuta, H. Watanabe, F. Tanaka, R. Kaji, I. Nakano, N. Kamatani, S. Tsuji, G. Sobue, Y. Nakamura, and S. Ikegawa: A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese. Human Molecular Genetics, 20:3684-3692, 2011
  580. A. Yosifova, T. Mushiroda, M. Kubo, A. Takahashi, Y. Kamatani, N. Kamatani, D. Stoianov, R. Vazharova, S. Karachanak, I. Zaharieva, I. Dimova, S. Hadjidekova, V. Milanova, N. Madjirova, I. Gerdjikov, T. Tolev, N. Poryazova, G. Kirov, M. Owen, M. O'Donovan, D. Toncheva, and Y. Nakamura: Genome wide association study on bipolar disorder in the Bulgarian population. Genes, Brain and Behavior, 10:789-797, 2011
  581. H. Mbarek, H. Ochi, Y. Urabe, V. Kumar, M. Kubo, N. Hosono, A. Takahashi, Y. Kamatani, D. Miki, H. Abe, T. Tsunoda, N. Kamatani, K. Chayama, Y. Nakamura, and K. Matsuda: A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. Human Molecular Genetics, 20:3884-3892, 2011
  582. S. Chung, M. Nakashima, H. Zembutsu, and Y. Nakamura: Possible involvement of NEDD4 in keloid formation; its critical role in fibroblast proliferation and collagen production. Proceedings of the Japan Academy, Ser.B Phys Biol Sci, 87:563-573, 2011
  583. M. Aragaki, K. Takahashi, H. Akiyama, E. Tsuchiya, S. Kondo, Y. Nakamura, and Y. Daigo: Characterization of a Cleavage Stimulation Factor, 3’ pre-RNA, Subunit 2, 64kDa (CSTF2) as a therapeutic target for lung cancer. Clinical Cancer Research, 17:5889-5900, 2011
  584. R. Nishino, A. Takano, H. Oshita, N. Ishikawa, H. Akiyama, H. Ito, H. Nakayama, Y. Miyagi, E. Tsuchiya, N. Kohno, Y. Nakamura, and Y. Daigo: Identification of Epstein-Barr virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer. Clinical Cancer Research, 17:6272-6286, 2011
  585. K. Masuda, A. Takano, H. Oshita, H. Akiyama, E. Tsuchiya, N. Kohno, Y. Nakamura, and Y. Daigo: Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer. Clinical Cancer Research, 17:7712-7722, 2011
  586. J.C. Chambers, W. Zhang, J. Sehm, Y. Nakamura et al. Genome-wide association study identifies loci influencing concentratikons of liver enzymes in plasma. Nature Genetics, 43:1131-1138, 2011
  587. N. Kumasaka , H. Fujisawa, N. Hosono, Y. Okada, A. Takahashi, Y. Nakamura, M. Kubo, and N. Kamatani: Platinum CNV: a bayesian gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data. Genetic Epidemiology, 35:831-844, 2011
  588. K. Kiyotani, T. Mushiroda, and Y. Nakamura: Pharmacogenomics of anticonvulsant agents (review). BioTech International, 22:16-18, 2011
  589. G. Toyokawa, H.-S. Cho, K. Masuda, M. Yoshimatsu, S. Hayami, M. Takawa, Y. Iwai, Y. Daigo, E. Tsuchiya, T. Tsunoda, H.I. Field, J.D. Kelly, D.E. Neal, Y. Maehara, B.A.J. Ponder, Y. Nakamura, and R. Hamamoto: The histone lysine methyltransferase Wolf-Hirschhorn Syndrome Candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway. Neoplasia, 13:887-898, 2011
  590. J. Li, D. Yang, Y. He, M. Wang, Z. Wen, L. Liu, J. Yao, K. Matsuda, Y. Nakamura, J. Yu, X. Jiang, S. Sun, Q. Liu, X. Jiang, Q. Song, M. Chen, H. Yang, F. Tang, X. Hu, J. Wang, Y. Chang, X. He, Y. Chen, and J. Lin: Associations of HLA-DP variants with hepatitis B virus infection in Southern and Northern Han Chinese populations: A multicenter case-control study. PLoS ONE, 6:e24221, 2011
  591. G. Toyokawa, H.-S. Cho, Y. Iwai, M. Takawa, M. Yoshimatsu, S. Hayami, K. Maejima, N. Shimizu, H. Tanaka, T. Tsunoda, H. I. Field, J. D. Kelly, D. E. Neal, B.A.J. Ponder, Y. Maehara, Y. Nakamura, and R. Hamamoto: The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6. Cancer Prevention Research, 4:2051-2061, 2011
  592. H.-S. Cho, G. Toyokawa, Y. Daigo, S. Hayami, K. Masuda, N. Ikawa, Y. Yamane, K. Maejima, M. Yoshimatsu, T. Tsunoda, H. I. Field, J. D. Kelly, D. E. Neal, B. A.J. Ponder, Y. Maehara, Y. Nakamura, and R. Hamamoto: The JmjC domain-containing histone demethylase KDM3A Is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene. Int. J. Cancer, :doi: 10.1002/ijc.26501, 2011
  593. M. Imamura, M. Iwata, H. Maegawa, H. Watada, H. Hirose, Y. Tanaka, K. Tobe, K. Kaku, A. Kashiwagi, R. Kawamori, Y. Nakamura, and S. Maeda: Genetic variants at CDC123/CAMK1D and SPRY2 are associated with susceptibility to type 2 diabetes in the Japanese population. Diabetologia, 54:3071-3077, 2011
  594. T. Ohshige, M. Iwata, S. Omori, Y. Tanaka, H. Hirose, K. Kaku, H. Maegawa, H. Watada, A. Kashiwagi, R. Kawamori, K. Tobe, T. Kadowaki, Y. Nakamura, and S. Maeda: Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese. PLoS ONE, 6:e26911, 2011
  595. C. Gieger, A. Radhakrishnan, A. Cvejic, W. Tang, Y. Nakamura, et al.: New gene functions in megakaryopoiesis and platelet formation. Nature, 480:201-208, 2011
  596. T. Hirota, H. Saeki, K. Tomita, S. Tanaka, K. Ebe, M. Sakashita, T. Yamada, S. Fujieda, A. Miyatake, S. Doi, T. Enomoto, N. Hizawa, T. Sakamoto, H. Masuko, T. Sasaki, T. Ebihara, M. Amagai, H. Esaki, S. Takeuchi, M. Furue, E. Noguchi, N. Kamatani, Y. Nakamura, M. Kubo, and M. Tamari: Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis: case-control studies. PLoS ONE, 6:e26987, 2011
  597. F. Innocenti, K. Owzar, N.L. Cox, P. Evans, M. Kubo, H. Zembutsu, C. Jiang, D. Hollis, T. Mushiroda, L. Li, P. Friedman, L. Wang, H. Hurwitz, K.M. Giacomini, H.L. McLeod, R.M. Goldberg, R.L. Schilsky, H.L. Kindler, Y. Nakamura, and M.J. Ratain: A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. Clinical Cancer Research, 18:577-584, 2011
  598. M. Furu, Y. Kajita, S. Nagayama, T. Ishibe, Y. Shima, K. Nishijo, D. Uejima, R Takahashi, T. Aoyama, T. Nakayama, T Nakamura, Y. Nakashima, M. Ikegawa, S. Imoto, T. Katagiri, Y. Nakamura, and J. Toguchida: Identification of AFAP1L1 as a prognostic marker for spindle cell sarcomas. Oncogene, 30:4015-4025, 2011
  599. K. Yasuno, M. Bakırcıoğlu, S.-K. Low, K. Bilgüvar, E. Gaál, Y.M. Ruigrok, M. Niemelä, A. Hata, P. Bijlenga, H. Kasuya, J.E. Jääskeläinen, D. Krex, G. Auburger, M. Simon, B. Krischek, A.K.Ozturk, S. Mane, G.J. Rinkel, H. Steinmetz, J. Hernesniemi, K. Schaller, H. Zembutsu, I. Inoue, A. Palotie, F. Cambien, Y. Nakamura, R.P. Lifton, and M. Günel: Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk. Proc. Natl. Acad. Sci. USA, 108:19707-19712, 2011
  600. K. Dabanaka, S.-Y. Chung, H. Nakagawa, Y. Nakamura, T. Okabayashi, T. Sugimoto, K. Hanazaki, and M. Furihata: PKIB expression strongly correlated with phosphorylated Akt expression in the breast cancers and also with triple negative breast cancer subtype. Medical Molecular Morphology, 17:7712-7722, 2011
  601. P.Y. Yew, T. Mushiroda, K. Kiyotani, G.K. Govindasamy, L.F. Yap, S.H. Teo, P.V. Lim, S. Govindaraju, K. Ratnavelu, C.K. Sam, Y.Y. Yap, A.S. Khoo, K.C. Pua, Y. Nakamura, The Malaysian NPC Study Group, and C.C. Ng Identification of a functional variant in SPLUNC1 associated with nasopharyngeal carcinoma susceptibility among Malaysian Chinese Molecular Carcinogenesis, :doi: 10.1002/mc.21857, 2011
  602. J. LI, D. Yang, Y. He, M. Wang, Z. Wen, L. Liu, J. Yao, K. Matsuda, Y. Nakamura, J. Yu, X. Jiang, S. Sun, Q Liu, X. Jiang, Q. Song, M. Chen, H. Yang, F. Tang, X. Hu, J. Wang, Y. Chang, X. He, Y. Chen, and J. Lin: Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study. PLoS One, 6:e24221, 2011
  603. K. Nakabayasi, A. Tajima, K. Yamamoto, A. Takahashi, K. Hata, Y. Takashima, M. Koyanagi, H. Nakaoka, T. Akamizu, N. Ishikawa, S. Kubota, S. Maeda, T. Tsunoda, M. Kubo, N. Kamatani, Y. Nakamura, T. Sasazuki, S. Shirasawa: Identification of independent risk loci for Graves' disease within the MHC in the Japanese population. Journal of Human Genetics, 56:772-778, 2011
  604. M. P. Goetz, D.J. Schaid, D.L. Wickerham, S. Safgren, T. Mushiroda, M. Kubo, A. Batzler, J.P. Costantino, V.G. Vogel, S. Paik, E.E. Carlson, D.A. Flockhart, N. Wolmark, Y. Nakamura, R.M. Weinshilboum, J.N. Ingle, M.M. Ames: Evaluation of CYP2D6 and efficacy of tamoxifen and raloxifene in women treated for breast cancer chemoprevention: results from the NSABP P1 and P2 clinical trials. Clinical Cancer Research, 17:6944-6951, 2011
  605. E. Noguchi, H. Sakamoto, T. Hirota, K. Ochiai, Y. Imoto, M. Sakashita, F. Kurosaka, A. Akasawa, S. Yoshihara, N. Kanno, Y. Yamada, N. Shimojo, Y. Kohno, Y. Suzuki, M.J. Kang, J.W. Kwon, S.J. Hong, K. Inoue, Y. Goto, F. Yamashita, T. Asada, H. Hirose, I. Saito, S. Fujieda, N. Hizawa, T. Sakamoto, H. Masuko, Y. Nakamura, I. Nomura, M. Tamari, T. Arinami, T. Yoshida, H. Saito, and K. Matsumoto: Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations. PLoS Genetics, 7:e1002170, 2011
  606. H. Abe, C.N. Hayes, H. Ochi, M. Tsuge, D. Miki, N. Hiraga, M. Imamura, S. Takahashi, M. Kubo, Y. Nakamura, N. Kamatani, and K. Chayama: Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state. Journal of Medical Virology, 83:1597-1607, 2011
  607. Y. Okada, K. Yamazaki, J. Umeno, A. Takahashi, N. Kumasaka, K. Ashikawa, T. Aoi, M. Takazoe, T. Matsui, A. Hirano, T. Matsumoto, N. Kamatani, Y. Nakamura, K. Yamamoto, and M. Kubo: HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease. Gastroenterology, 141:864-871, 2011
  608. H. Akaza, T. Tsukamoto, T. Fujioka, Y. Tomita, T. Kitamura, S. Ozono, T. Miki, S. Naito, H. Zembutsu, and Y. Nakamura: Combined immunotherapy with low-dose IL-2 plus IFN-alpha for metastatic renal cell carcinoma: survival benefit for selected patients with lung metastasis and serum sodium level. Jpn J. Clin. Oncol., 41:1023-1030, 2011
  609. N. Hiraga, H. Abe, M. Imamura, M. Tsuge, S. Takahashi, C.N. Hayes, H. Ochi, C. Tateno, K. Yoshizato, Y. Nakamura, N. Kamatani, and K. Chayama: Impact of viral amino acid substitutions and host interleukin-28b polymorphism on replication and susceptibility to interferon of hepatitis C virus. Hepatology, 54:764-771, 2011
  610. K. Yamaguchi, M Sakai, J. Kim, S. Tsunesumi, T. Fujii, T. Ikenoue, Y. Yamada, Y. Akiyama, Y. Muto, R. Yamaguchi, S. Miyano, Y. Nakamura, and Y. Furukawa: MRG-binding protein contributes to colorectal cancer development. Cancer Science, 102:1486-92, 2011

    2012↑ページトップへ

  611. N. Akuta, F. Suzuki, M. Hirakawa, Y. Kawamura, H. Sezaki, Y. Suzuki, T. Hosaka, M. Kobayashi, M. Kobayashi, S. Saitoh, Y. Arase, K. Ikeda, K. Chayama, Y. Nakamura, and H. Kumada: Amino acid substitution in HCV core/NS5A region and genetic variation near IL28B gene affect treatment efficacy to interferon plus ribavirin combination therapy. Intervirology, 55:231-241, 2012
  612. K. Kiyotani, T. Mushiroda, Y. Nakamura, and H. Zembutsu: Pharmacogenomics of tamoxifen: roles of drug metabolizing enzymes and transporters. Drug Metabolism and Pharmacokinetics, 27:122-131, 2012
  613. J. Koinuma, H. Akiyama, M. Fujita, M. Hosokawa, E. Tsuchiya, S. Kondo, Y. Nakamura, and Y. Daigo: Characterization of an Opa interacting protein 5 (OIP5) involved in lung and esophageal carcinogenesis. Cancer Science, 103:577-586, 2012
  614. K. Kiyotani, S. Uno, T. Mushiroda, A. Takahashi, M. Kubo, N. Mitsuhata, S. Ina, C. Kihara, Y. Kimura, H. Yamaue, K. Hirata, Y. Nakamura, and H. Zembutsu: Genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy. Pharmacogenetics and Genomics, 22:229-235, 2012
  615. Y. Okada, M. Kubo, H. Ohmiya, A. Takahashi, N. Kumasaka, N. Hosono, S. Maeda, W. Wen, R. Dorajoo, M.-J. Go, W. Zheng, N. Kato, J.-Y. Wu, Q. Lu, the GIANT consortium, T. Tsunoda, K. Yamamoto, Y. Nakamura, N. Kamatani, and T. Tanaka: Common variants at CDKAL1 and KLF9 are associated with body mass index in East Asian populations. Nature Genetics, 44:302-306, 2012
  616. W. Wen, Y.S. Cho, W. Zheng, R. Dorajoo, Y. Nakamura, et al.: Meta-analysis identifies common variants associated with body mass index in east Asians. Nature Genetics, 44:307-311, 2012
  617. R. Abo, S. Hebbring, Y. Ji, H. Zhu, Z.-B. Zeng, A. Batzler, G. D. Jenkins, J. Biernacka, K. Snyder, M. Drews, O. Fiehn, B. Fridley, D.Schaid, N. Kamatani, Y. Nakamura, M. Kubo, T. Mushiroda, R. Kaddurah-Daouk, D. A. Mrazek, and R. M. Weinshilboum: Merging pharmacometabolomics with pharmacogenomics using “1000 Genomes” SNP imputation: Selective serotonin reuptake inhibitor response pharmacogenomics. Pharmacogenetics and Genomics, 22:247-253, 2012
  618. H. Nakagawa, S. Akamatsu, R. Takata, A. Takahashi, M. Kubo, and Y. Nakamura: Prostate cancer genomics, biology, and risk assessment through genome-wide association studies. Cancer Science, 103:607-613, 2012
  619. K. Kiyotani, T. Mushiroda, T. Tsunoda, T. Morizono, N. Hosono, M. Kubo, Y. Tanigawara, C.K. Imamura, D.A. Flockhart, F. Aki, K. Hirata, Y. Takatsuka, M. Okazaki, S. Ohsumi, T. Yamakawa, M. Sasa, Y. Nakamura, and H. Zembutsu: A Genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese. Human Molecular Genetics, 21:1665-1672, 2012
  620. H. Yoshioka, S. Yamamoto, H. Hanaoka, Y. Iida, P. Paudya, T. Higuchi, H. Tominaga, N. Oriuchi, H. Nakagawa, Y. Shiba, K. Yoshida, R. Osawa, T. Katagiri, T. Tsunoda, Y. Nakamura, and K. Endo: In vivo therapeutic effect of CDH3/P-cadherin-targeting radioimmunotherapy. Cancer Immunology, Immunotherapy, 61:1211-1220, 2012
  621. C. Tanikawa, Y. Urabe, K. Matsuo, M. Kubo, A. Takahashi, H. Ito, K. Tajima, N. Kamatani, Y. Nakamura, and K. Matsuda: Genome wide association study identified two susceptible loci for duodenal ulcer in Japanese population. Nature Genetics, 44:430-434, 2012
  622. Y. Urabe, C. Tanikawa, A. Takahashi, Y. Okada, T. Morizono, T. Tsunoda, N. Kamatani, K. Kohri, K. Chayama, M. Kubo, Y. Nakamura, and K. Matsuda: Genome-wide association study of nephrolithiasis in Japanese population identifies novel susceptible loci at 5q35.3, 7p14.3 and 13q14.1. PLoS Genetics, 8:e1002541, 2012
  623. S.-K. Low, A. Takahashi, P.-C. Cha, H. Zembutsu, N. Kamatani, M. Kubo, and Y. Nakamura: Genome-wide association study for intracranial aneurysm in Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA. Human Molecular Genetics, 21:2102-2110, 2012
  624. C. Tanikawa, M. Espinosa, A. Suzuki, K. Masuda, K. Yamamoto, E. Tsuchiya, K. Ueda, Y. Daigo, Y. Nakamura, and K. Matsuda: Regulation of histone modification and chromatin structure by the p53-PADI4 pathway. Nature Communications, :DOI 10.1038, 2012
  625. P.-C. Cha, H. Zembutsu, A. Takahashi, M. Kubo, N. Kamatani, and Y. Nakamura: A genome-wide association study (GWAS) identifies SNP in DCC is associated with gallbladder cancer (GC) in the Japanese population. Journal of Human Genetics, 57:235-237, 2012
  626. S. Akamatsu, R. Takata, C.A. Haiman, A. Takahashi, T. Inoue, M. Kubo, M. Furihata, N. Kamatani, J. Inazawa, G.K. Chen, L.L. Marchand, L.N. Kolonel, T. Katoh, Y. Yamano, M. Yamakado, H. Takahashi, H. Yamada, S. Egawa, T. Fujioka, B.E. Henderson, T. Habuchi, O. Ogawa, Y. Nakamura, and H. Nakagawa: Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese. Nature Genetics, 44:426-429, 2012
  627. W.-C. Chang, C.-H. Lee., T. Hirota, L.-F. Wang, S. Doi, A. Miyatake, T. Enomoto, K. Tomita, M. Sakashita, T. Yamada, S. Fujieda, K. Ebe, H. Saeki, S. Takeuchi, M. Furue, W.-C. Chen, Y.-C. Chiu, W. P. Chang, C.-H. Hong, E. Hsi, S.-H. H. Juo, H.-S. Yu, Y. Nakamura, and M. Tamari: ORAI1 genetic polymorphisms associated with the susceptibility of atopic dermatitis in Japanese andTaiwanese populations. PLoS ONE, 1:e29387, 2012
  628. W. Osman, Y. Okada, Y. Kamatani, M. Kubo, K. Matsuda, and Y. Nakamura: Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in the Japanese population. PLoS ONE, 7:e32683 Epub, 2012
  629. H.H. Nguyen, R. Takata, S. Akamatsu, D. Shigemizu, T. Tsunoda, M. Furihata, A. Takahashi, M. Kubo, N. Kamatani, O. Ogawa, T. Fujioka, Y. Nakamura, and H. Nakagawa: IRX4 at 5p15 suppresses prostate cancer growth through the interaction with vitamin D receptor, conferring prostate cancer susceptibility. Human Molecular Genetics, 21:2076-2085, 2012
  630. Y. Okada, C. Terao, K. Ikari, Y. Kochi, K. Ohmura, A. Suzuki, T. Kawaguchi, E. Stahl, F. Kurreman, N. Nishida, H. Ohmiya, K. Myouzen, M. Takahashi, T. Sawada, Y. Nishioka, M. Yukioka, T. Matsubara, S. Wakitani, R. Teshima, S. Tohma, K. Takasugi, K. Shimada, A. Murasawa, S. Honjo, K. Matsuo, H. Tanaka, K. Tajima, T. Suzuki, T. Iwamoto, Y. Kawamura, H. Tanii, Y. Okazaki, T. Sasaki, P.K. Gregersen, L. Padyukov, J. Worthington, K.A. Siminovitch, M. Lathrop, A. Taniguchi, A. Takahashi, K. Tokunaga, M. Kubo, Y. Nakamura, N. Kamatani, T. Mimori, R.M. Plenge, H. Yamanaka, S. Momohara, R. Yamada, F. Matsuda, and K. Yamamoto: Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. Nature Genetics, 44:511-516, 2012
  631. W. Jongjaroenpraser, T. Phusantisampan, S. Mahasirimongkol, T. Mushiroda, N. Hirankarn, T. Snabboon, S. Chanprasertyotin, P. Tantiwong, S. Soonthornpun, P. Rattanapichart, S. Mamanasiri, T. Himathongkam, B. Ongphiphadhanakul, A. Takahashi, N. Kamatani, M. Kubo, and Y. Nakamura: A genome-wide association study identifies novel susceptibility loci for thyrotoxic hypokalemic periodic paralysis. Journal of Human Genetics, 57:301-304, 2012
  632. M. Aoki, N. Hosono, S. Kakata, Y. Nakamura, N. Kamatani, and M. Kubo: New pharmacogenetic test for detecting HLA-A*31:01 allele using invaderPlus assay. Pharmacogenetics and Genomics, 22:441-446, 2012
  633. K. Kiyotani, T. Mushiroda, C.K. Imamura, Y. Tanigawara, N. Hosono, M. Kubo, M. Sasa, Y. Nakamura, and H. Zembutsu: Dose-adjustment study of tamoxifen based on CYP2D6 genotypes in Japanese breast cancer patients. Breast Cancer Res Treat, 131:137-145, 2012
  634. C. Tanikawa, H. Nakagawa, Y. Furukawa, Y. Nakamura, and K. Matsuda: CLCA2 as a p53-inducible senescence mediator. Neoplasia, 14:141-149, 2012
  635. Y. Yamaguchi-Kabata, T. Tsunoda, N. Kumasaka, A. Takahashi, N. Hosono, M. Kubo, Y. Nakamura, and N. Kamatani: Genetic differences in the two main groups of the Japanese population based on autosomal SNPs and haplotypes. Journal of Human Genetics, 57:326-334, 2012
  636. Y. Onouchi, K. Ozaki, J.C. Burns, C. Shimizu, M. Terai, H. Hamada, T. Honda, H. Suzuki, T. Suenaga, T. Takeuchi, N. Yoshikawa, Y. Suzuki K. Yasukawa, R. Ebata, K. Higashi, T. Saji, Y. Kemmotsu, S. Takatsuki, K. Ouchi, F. Kishi, T. Yoshikawa, T. Nagai, K. Hamamoto, Y. Sata, A. Honda, H. Kobayashi, J. Sato, S. Shibuta, M. Miyawaki, K. Oishi, H. Yamaga, N. Aoyagi, S. Iwahashi, R. Miyashita, Y. Murata, K. Sasago, A. Takahashi, N. Kamatani, M. Kubo, T. Tsunoda, A. Hata, Y. Nakamura, T. Tanaka, and Japan Kawasaki Disease Genome Consortium & U.S. Kawasaki Disease Genetics Consortium: A genome-wide association study identifies three new loci for Kawasaki disease. Nature Genetics, 44:517-521, 2012
  637. W. Osman, S.-K. Low, A. Takahashi, M. Kubo, and Y. Nakamura: A Genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma. Human Molecular Genetics, 21:2836-2842, 2012
  638. S. Mahasirimongkol, H. Yanai, T. Mushiroda, W. Promphittayarat, S. Wattanapokayakit, J. Promjai, R. Yuliwulandari, N. Wichukchinda, A. Yowang, N. Yamada, P. Kantipong, A. Takahashi, M. Kubo, P. Sawanpanyalert, N. Kamatani, Y. Nakamura, and K. Tokunaga: Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis. Journal of Human Genetics, 57:363-367, 2012
  639. M Liu, L. Wang, T. Bongartz, J.R. Hawse, S.N. Markovic, D.J. Schaid, T. Mushiroda, M. Kubo, Y. Nakamura, N. Kamatani, P.E. Goss, J.N. Ingle, and R.M. Weinshilboum: Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression. Breast Cancer Research, 9:R41, 2012
  640. M. Imamura, S. Maeda, T. Yamauchi, K. Hara, K. Yasuda, T. Morizono, A. Takahashi, M. Horikoshi, M. Nakamura, H. Fujita, T. Tsunoda, M. Kubo, H. Watada, H. Maegawa, M. Okada-Iwabu, M. Iwabu, N. Shojima, T. Ohshige, S. Omori, M. Iwata, H. Hirose, K. Kaku, C. Ito, Y. Tanaka, K. Tobe, A. Kashiwagi, R. Kawamori, M. Kasuga, N. Kamatani, Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, Y. Nakamura, and T. Kadowaki: A single nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations. Human Molecular Genetics, 21:3042-3049, 2012
  641. P.T. Ellinor, K.L. Lunetta, C.M. Albert, N.L. Glazer, M.D. Ritchie, A.V. Smith, D.E. Arking, M. Müller-Nurasyid, B.P. Krijthe, S.A. Lubitz, J.C. Bis, M.K. Chung, K. Ozaki, J.D. Roberts, J.G. Smith, A. Pfeufer, M.F. Sinner, K. Lohman, J. Ding, N.L. Smith, J.D. Smith, M. Rienstra, K.M. Rice, D.R. Van Wagoner, J.W. Magnani, R. Wakili, S. Clauss, J.I. Rotter, G. Steinbeck, L.J. Launer, R.W. Davies, M. Borkovich, T.B. Harris, H. Lin, U. Völker, H. Völzke, D.J. Milan, A. Hofman, E. Boerwinkle, L.Y. Chen, E.Z. Soliman, B.F. Voight, G. Li, A. Chakravarti, M. Kubo, U. Tedrow, L.M. Rse, P.M. Ridker, D. Conen, T. Tsunoda, T. Furukawa, N. Sotoodehnia, S. Xu, N. Kamatani, D. Levy, Y. Nakamura, B. Parvez, S. Mahida, K.L. Furie, J. Rosand, R. Muhammad, B.M. Psaty, T. Meitinger, S. Perz, H.-E. Wichmann, J.C.M. Witteman, W.H.L. Kao, S. Kathiresan, D.M. Roden, A.G. Uitterlinden, F. Rivadeneira, B. McKnight, M. Sjögren, A.B. Newman, Y. Liu, M.H. Gollob, O. Melander, T. Tanaka, B.H.C. Stricker, S.B. Felix, A. Alonso, D. Darbar, J. Barnard, D.I. Chasman, S.R. Heckbert, E.J. Benjamin, V. Gudnason, and S. Kääb: Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nature Genetics, 44:670-675, 2012
  642. R. Osawa, T. Tsunoda, S. Yoshimura, T. Watanabe, M. Miyazawa, M. Tani, K. Takeda, H. Nakagawa, Y. Nakamura, and H. Yamaue: Identification of HLA-A24-restricted novel T cell epitope peptides derived from P-cadherin and kinesin family member 20A. Journal of Biomedicine and Biotechnology, :doi:10.1155/2012/848042, 2012
  643. M. Takawa, H.-S. Cho, S. Hayami, G. Toyokawa, M. Kogure, Y. Yamane, Y. Iwai, K. Maejima, K. Ueda, A. Masuda, N. Dohmae, H.I. Field, T. Tsunoda, T. Kobayashi, T. Akasu, M. Sugiyama, S. Ohnuma, Y. Atomi, B.A.J. Ponder, Y. Nakamura, and R. Hamamoto: Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression. Cancer Research, 72:3217-3227, 2012
  644. H.-S. Cho, S. Hayami, G. Toyokawa, K. Maejima, Y. Yamane, T. Suzuki, N. Dohmae, M. Kogure, D. Kang, D.E. Neal, B.A.J. Ponder, H. Yamaue, Y. Nakamura, and R. Hamamoto: RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation. Neoplasia, 14:476-486, 2012
  645. A. Fujimoto, Y. Totoki, T. Abe, K. A. Boroevich, F. Hosoda, H. H. Nguyen, M. Aoki, N. Hoshono, M. Kubo, F. Miya, Y. Arai, H. Takahashi, T. Shirakihara, M. Nagasaki, T. Shibuya, K. Nakano, K. Watanabe-Makino, H. Tanaka, H. Nakamura, J. Kusuda, H. Ojima, K. Shimada, T. Okusaka, M. Ueno, Y. Shigekawa, Y. Kawakami, K. Arihiro, H. Ohdan, K. Gotoh, O. Ishikawa, S. Ariizumi, M. Yamamoto, T. Yamada, K. Chayama, T. Kosuge, H. Yamaue, N. Kamatani, S. Miyano, H. Nakagama, Y. Nakamura, T. Tsunoda, T. Shibata, and H. Nakagawa: Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nature Genetics, 44:760-764, 2012
  646. W. Obara, R. Ohsawa, M. Kanehira, R. Takata, T. Tsunoda, K. Yoshida, K. Takeda, T. Katagiri, Y. Nakamura, T. Fujioka: Cancer peptide vaccine therapy developed from ongoantigens that were identified through genome-wide expression profile analysis for bladder cancer. Japanese Journal of Clinical Oncology, 42:591-600, 2012
  647. K. Okuno, F. Sugiura, K. Itoh, Y. Yoshida, T. Tsunoda, Y. Nakamura: Recent advances in active specific cancer vaccine threatment for colorectal cancer. Current Pharmacology and Biotechnology, in press:, 2012
  648. A. Toyama, A. Suzuki, T. Shimada, C. Aoki, Y. Aoki, Y. Umino, Y. Nakamura, D. Aoki, and TA. Sato: Proteomic characterization of ovarian cancers identifying annexin-A4, phosphoserine aminotransferase, cellular retinoic acid-binding protein 2, and serpin B5 as histology-specific biomarkers. Cancer Science, 103:747-755, 2012
  649. Y. Okada, K. Shimane, Y. Kochi, T. Tahira, A. Suzuki, K. Higasa, A. Takahashi, T. Horita, T. Atsumi, T. Ishii, A. Okamoto, K. Fujio, M. Hirakata, H. Amano, Y. Kondo, S. Ito, K. Takada, A. Mimori, K. Saito, M. Kamachi, Y. Kawaguchi, K. Ikari, OW Mohammed, K. Matsuda, C. Terao, K. Ohmura, K. Myouzen, N. Hosono, T. Tsunoda, N. Nishimoto, T. Mimori, F. Matsuda, Y. Tanaka, T. Sumida, H. Yamanaka, Y. Takasaki, T. Koike, T. Horiuchi, K. Hayashi, M. Kubo, N. Kamatani, R. Yamada, Y. Nakamura, and K. Yamamoto: A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese. PLoS Genetics, 8:e10024, 2012
  650. H. Ochi, CN. Hayes, H. Abe, Y. Hayashida, T. Uchiyama, N. Kamatani, Y. Nakamura, and K. Chayama:. Toward the establishment of a prediction system for the personalized treatment of chronic hepatitis C. Journal of Infectious Diseases, 15:204-210, 2012
  651. M. Maimbo, K. Kiyotani, T. Mushiroda, C. Masimirembwa, and Y. Nakamura: CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans. European Journal of Clinical Pharmacology, 68:267-271, 2012
  652. Y. Okada, X. Sim, M. J. Go, C.-H. Chen, D. Gu, F. Takeuchi, A. Takahashi, S. Maeda, T. Tsunoda, P. Chen, S.-C. Lim1, T.-Y Wong, J. Liu1, T. L. Young, T. Aung, M. Seielstad, Y.-Y. Teo, Y. J. Kim, J.-Y. Lee, B.-G. Han, D. Kang, F.-J. Tsai, L.-C. Chang, S.-J. C. Fann, Y.-T. Chen, H. Mei, D. C. Rao, J. E. Hixson, S. Chen, T. Katsuya, M. Isono, T. Ogihara, J. C. Chambers, W. Zhang, J. S. Kooner, the KidneyGen consortium, the CKDGen consortium , E. Albrecht, the GUGC consortium , K. Yamamoto, M. Kubo, Y. Nakamura, N. Kamatani, N. Kato, J. He, J.-Y. Wu, Y. S. Cho, E.-S. Tai, and T. Tanaka: Genome-wide meta-analysis identified multiple novel loci associated with kidney function-related traits in East Asian populations. Nature Genetics, in press:, 2012
  653. M.G. Dunlop, S.E. Dobbins, S.M. Farrington, A.M.Jones, C. Palles, N. Whiffin, A. Tenesa, S. Spain, P. Broderick, L.-Y. Ooi, E. Domingo, C. Smillie, M. Henrion, M. Frampton, L. Martin, G. Grimes, M. Gorman, C. Semple, Y.P. Ma, E. Barclay, J. Prendergast, J.-B. Cazier, B. Olver, S. Penegar, S. Lubbe, I. Chander, L.G. Carvajal-Carmona, S. Ballereau, A. Lloyd, J. Vijayakrishnan, L. Zgaga, I. Rudan, E. Theodoratou, The Colorectal Tumour Gene Identification (CORGI) Consortium, J.M. Starr, I. Deary, I. Kirac, D. Kovacevi, L.A. Aaltonen, L. Renkonen-Sinisalo, J.-P. Mecklin, K. Matsuda, Y. Nakamura, Y. Okada, S. Gallinger, D.J. Duggan, D. Conti, P. Newcomb, J. Hopper, M.A. Jenkins, F. Schumacher, G. Casey, D. Easton, M. Shah, P. Pharoah, A. Lindblom, T. Liu, The Swedish Low-Risk Colorectal Cancer Study Group, C. G Smith, H. West, J.P. Cheadle, The COIN Collaborative Group, R. Midgley, D.J. Kerr, H. Campbell, I.P. Tomlinson, and R.S. Houlston: Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Nature Genetics, 44:770-776, 2012
  654. T. Masuzawa, Y. Fujiwara, K. Okada, A. Nakamura, S. Takiguchi, K. Nakajima, H. Miyata, M. Yamasaki, Y. Kurokawa, R. Osawa, K. Takeda, K. Yoshida, T. Tsunoda, Y. Nakamura, M. Mori, and Y. Doki: Phase I/II study of S-1 plus cisplatin combined with peptide vaccines for human vascular endothelial growth factor receptor 1 and 2 in patients with advanced gastric cancer. International Journal of Oncology, in press:, 2012
  655. K. Kusakabe, N. Ide, Y. Daigo, T. Itoh, K. Higashino,Y. Okano, G. Tadano, Y. Tachibana, Y. Sato, M. Inoue, T. Wada, M. Iguchi, T. Kanazawa, Y. Ishioka, K. Dohi, S. Tagashira, Y. Kido, S. Sakamoto, K. Yasuo, M. Maeda, T. Yamamoto, M. Higaki, T. Endoh, K. Ueda, T. Shiota, H. Murai, and Y. Nakamura: Diaminopyridine-based potent and selective MPS1 kinase inhibitors binding to an unusual flipped-peptide conformation. Medical Chemistry Letters, in press:, 2012
  656. T. Fujitomo, Y. Daigo, K. Matsuda, K. Ueda, and Y. Nakamura: Critical function for nuclear envelope protein TMEM209 in human pulmonary carcinogenesis. Cancer Research, 72:4110-4118, 2012
  657. K. Shiraishi, H. Kunitoh, Y. Daigo, A. Takahashi, K. Goto, H. Sakamoto, S. Ohnami, Y. Shimada, K. Ashikawa, A. Saito, S. Watanabe, K. Tsuta, N. Kamatani, T. Yoshida, Y. Nakamura, J. Yokota, M. Kubo, and T. Kohno: A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population. Nature Genetics, 44:900-903, 2012
  658. M.-H. Nguyen, K. Ueda, Y. Nakamura, and Y. Daigo: Identification of a novel oncogene MMS22L involved in lung and esophageal carcinogenesis. International Journal of Oncology, in press:, 2012
  659. K. Kono , H. Iinuma, Y. Akutsu, H. Tanaka, N. Hayashi, Y. Uchikado, T. Noguchi, H. Fujii, K. Okinaka, R. Fukushima, H. Matsubara, M. Ohira, H. Baba, S. Natsugoe, S. Kitano, K. Yoshida, T. Tsunoda, and Y. Nakamura: Multicenter, Phase II clinical trial of Cancer Vaccination for Advanced Esophageal cancer with Three Peptides derived from Novel Cancer-Testis Antigens. Journal of Trasnlational Medicine, 10:141 doi: 10.1186/1479-5876-10-141., 2012
  660. B. E. Himes, X. Jiang, R. Hu, A. C. Wu, J. A. Lasky-Su, B. J. Klanderman, J. Ziniti, J. Senter-Sylvia, J. J. Lima, C. G. Irvin, S. P. Peters, D. A. Meyers, E. R. Bleecker, M. Kubo, M. Tamari, Y. Nakamura, S. J. Szefler, R. F. Lemanske Jr., R. S. Zeiger, R. C. Strunk, F. D. Martinez, J. P. Hanrahan, G. H. Koppelman, D. S. Postma, M. A. E. Nieuwenhuis, J. M. Vonk, R. A. Panettieri Jr., A. Markezich, E. Israel, V. J. Carey, K. G. Tantisira, A. A. Litonjua, Q. Lu, and S. T. Weiss: Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene. PLoS Genetics, 8:e1002824, 2012
  661. M. Takahashi, Y. Furukawa, H. Shimodaira, M. Sakayori , T. Moriya, Y. Moriya, Y. Nakamura. and C. Ishioka: Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome. Familial Cancer, 10:DOI 10.1007/s10689-012-9547-, 2012
  662. Y. Ji, J. M. Biernacka, S. Hebbring, Y Chai, G. D. Jenkins, A. Batzler, K. A. Snyder, M. S. Drews, Z. Desta, D. Flockhart, T. Mushiroda, M. Kubo, Y. Nakamura, N. Kamatani, D. Schaid, R. M. Weinshilboum and D. A. Mrazek: Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: genome-wide associations and functional genomics. Pharmacogenomics Journal, in press:, 2012
  663. R. M. Baldwin, K. Owzar, H. Zembutsu, A. Chhibber, M. Kubo, C. Jiang, D. Watson, R. J. Eclov, J. Mefford, H. L. McLeod, P. N. Friedman, C. A. Hudis, E. P. Winer, E. M. Jorgenson, J. S. Witte, L. N. Shulman, Y. Nakamura, M. J. Ratain and D. L. Kroetz: A Genome-Wide Association Study Identifies Novel Loci for Paclitaxel-Induced Sensory Peripheral Neuropathy in CALGB 40101. Clinical Cancer Research, 18:5099-5109, 2012
  664. T.Hirota, A. Takahashi, M. Kubo, T. Tsunoda, K. Tomita, M. Sakashita, T. Yamada, S. Fujieda, S. Tanaka, S. Doi, A. Miyatake, T. Enomoto, C. Nishiyama, N. Nakano, K. Maeda, K. Okumura, H. Ogawa, S. Ikeda, E. Noguchi, T. Sakamoto, N. Hizawa, K. Ebe, H. Saeki, T. Sasaki, T. Ebihara, M. Amagai, S. Takeuchi, M. Furue, Y. Nakamura, and M. Tamari Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population Nature Genetics, in press, 2012
  665. V. Kumar, P.H.Y. Lo, H. Sawai, N.Kato, A. Takahashi, Z. Deng, Y. Urabe, H. Mbarek, K. Tokunaga, Y. Tanaka, M. Sugiyama, M. Mizokami, R. Muroyama, R. Tateishi, M. Omata, K. Koike, C. Tanikawa, N. Kamatani, M. Kubo, Y. Nakamura, and K. Matsuda Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma Plos ONE, in press, 2012
  666. K. Shimane, Y. Kochi, A. Suzuki, Y. Okada, T. Ishii, T. Horita, K. Saito, A. Okamoto, N. Nishimoto, K. Myouzen, M. Kubo, M. Hirakata, T. Sumida, Y. Takasaki, R. Yamada, Y. Nakamura, N. Kamatani and K. Yamamoto An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes. Rheumatology, in press, 2012
  667. S. Elgazzar, H. Zembutsu, A. Takahashi, M. Kubo, F. Aki, K. Hirata, Y. Takatsuka, M. Okazaki, S. Ohsumi, T. Yamakawa, M. Sasa, T. Katagiri, Y. Miki, and Y. Nakamura: A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor positive breast cancer in Japanese Journal of Human Genetics, in press, 2012
  668. D. Kang, , H.-S. Cho, G. Toyokawa, M. Kogure, Y. Yamane, Y. Iwai, S. Hayami, T. Tsunoda, H. I. Field, K. Matsuda, D. E. Neal, B. A.J. Ponder, Y. Maehara, Y. Nakamura, and R. Hamamoto: The Histone Methyltransferase Wolf-Hirschhorn Syndrome Candidate 1-like 1 (WHSC1L1) Is Involved in Human Carcinogenesis Genes Chromosomes and Cancer, in press, 2012
  669. H.-S. Cho, T. Shimazu, G. Toyokawa, Y. Daigo, Y. Maehara, S. Hayami, A. Ito, K. Masuda, N. Ikawa, H. I. Field, E. Tsuchiya, S. Ohnuma, B. A.J. Ponder, M. Yoshida, Y. Nakamura, and R. Hamamoto:　　　 Enhanced HSP70 lysine 561 methylation promotes proliferation of cancer cells through activation of aurora kinase B Nature Communications, :DOI 10.1038/ncomms2074, 2012
  670. S. Akamatsu, A. Takahashi, R. Takata, M. Kubo, T. Inoue, T. Morizono, T. Tsunoda, N. Kamatani, C. A. Haiman, P. Wan, G. K. Chen, L. Le Marchand, L. N. Kolonel, B. E. Henderson, T. Fujioka, T. Habuchi, Y. Nakamura, O. Ogawa, and H. Nakagawa: Reproducibility, Performance, and Clinical Utility of a Genetic Risk Prediction Model for Prostate Cancer in Japanese PLOS One, in press, 2012
  671. A. Toyama, H. Nakagawa, K. Matsuda, T. Sato, Y. Nakamura, and K. Ueda: Quantitative structural characterization of local N-glycan microheterogeneity in therapeutic antibodies by energy-resolved oxonium ion monitoring. Analytical Chemistry, in press, 2012
  672. D.R. Nyholt, S.-K. Low, C.A. Anderson, J.N. Painter, S. Uno, A.P. Morris, S. MacGregor, S.D. Gordon, A.K. Henders, N.G. Martin, J. Attia, E.G. Holliday, M. McEvoy, R.J. Scott, S.H. Kennedy, S.A. Treloar, S.A. Missmer, S. Adachi, K. Tanaka, Y. Nakamura, K.T. Zondervan, H. Zembutsu, and G.W. Montgomery: Multi-ethnic GWA meta-analysis identifies new endometriosis risk loci Nature Genetics, in press, 2012
  673. K.M. Giacomini, S.W. Yee, M.J. Ratain, R.M. Weinshilboum, N. Kamatani and Y. Nakamura: Pharmacogenomics and patient care: one size does not fit all. Science Translational Medicine, in press, 2012
  674. R. Takata, K. Matsuda, J. Sugimura, W. Obara, T. Fujioka, K. Okihara, N. Takaha, T. Miki, S. Ashida, K. Inoue, C. Tanikawa, T. Shuin, S. Sasaki, Y. Kojima, K. Kohri, M. Kubo, M. Yamaguchi, Y. Ohnishi, and Y. Nakamura Impact of four loci on serum tamsulosin hydrochloride concentration. Journal of Human Genetics, in press, 2012
  675. T. Fukawa,, M. Ono,T. Matsuo,H. Uehara, T. Miki, Y. Nakamura,H. Kanayama, and T. Katagiri: DDX31 regulates the p53-HDM2 pathway and rRNA gene transcription through its interaction with NPM1 in renal cell carcinomas Cancer Research, in press, 2012
  676. E. Danese, M. Montagnana, J.A. Johnson, A.E. Rettie, C.F. Zambon, S.A. Lubitz, G. Suarez-Kurtz, L.H. Cavallari, L. Zhao, M. Huang, Y. Nakamura, T. Mushiroda, M.K. Kringen, P. Borgiani, C. Ciccacci, N.T. Au, T. Langaee, V. Siguret, M.-A. Loriot, H. Sagreiya, R.B. Altman, M.H.A. Shahin, S.A. Scott, S.I. Khalifa, B. Chowbay, I.M. Suriapranata, M. Teichert, B.H. Stricker, M. Taljaard, M.R. Botton, J.E. Zhang, M. Pirmohamed, X. Zhang, J.F. Carlquist, B.D. Horne, M.T.M. Lee, V. Pengo, G.C. Guidi, P. Minuz, and C. Fava Impact of the CYP4F2 p.V433M polymorphism on coumarin dose requirement: systematic review and meta-analysis Clinical Pharmacology & Therapeutics, in press, 2012
  677. M. Komatsu, T. Yoshimaru, T. Matsuo, K. Kiyotani, Y. Miyoshi, T. Tanahashi, K. Rokutan, R. Yamaguchi, A. Saito, S. Imoto, S. Miyano, Y. Nakamura, M. Sasa, M. Shimada, and T. Katagiri: Molecular features of triple negative breast cancers by genome-wide gene expression profiling analysis International Journal of Oncology, in press, 2012
Copyright © 2012 Yusuke Nakamura's Labo., All rights reserved.
Last update: 2012.11.13

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