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年別　論文リスト
[1975-1985] [1986] [1987] [1988] [1989]
[1990] [1991] [1992] [1993] [1994]
[1995] [1996] [1997] [1998] [1999]
[2000] [2001] [2002] [2003] [2004]
[2005] [2006] [2007] [2008] [2009]
[2010] [2011] [2012]

[論文被引用件数（500回以上）の表]
[[年別　論文数の表]
[主要雑誌別　論文数の表]

1975-1985

  1. Y. Miyake , Y. Nakamura, N. Takayama and K. Horiike: Alpha reduced nicotinamide adenine dinucleotides-dependent reductase reactions of rat liver microsomes. J. Biochem. 78:773-783, 1975
  2. T. Noguchi , H. Inoue, Y. Nakamura, H. Chen, K. Matsubara and T. Tanaka: Molecular cloning of cDNA sequences for rat M2-type pyruvate kinase and regulation of its mRNA. J. Biochem. 258:15220-15223 ,1984
  3. Y. Nakamura, M. Ogawa, T. Nishide, M. Emi, S. Himeno, G. Kosaki and K. Matsubara: Sequences of cDNAs for human salivary and pancreatic alpha-amylase. Gene 28:263-270 ,1984
  4. K. Ishizaki , A. Noda, M. Ikenaga, K. Ida, K. Omoto, Y. Nakamura and K. Matsubara: Restriction fragment length polymorphism detected by human salivary amylase cDNA. Human Genetics 71:261-262 ,1985
  5. T. Yamamoto , Y. Nakamura, T. Nishide, M. Emi, M. Ogawa, T. Mori and K. Matsubara: Molecular cloning and nucleotide sequence of human pancreatic secretory trypsin inhibitor (PSTI) cDNA. Biochem. Biophy. Research Comm. 132:605-612 ,1985
  6. R. White, S. Woodward, M. Leppert, P. O'Connell, Y. Nakamura, M. Hoff, J. Herbst, J-M. Lalouel, M. Dean and G. Vande Woude: A closely linked genetic marker for cystic fibrosis. Nature 318:382-384 ,1985

    1986　　↑ページトップへ

  7. T. Nishide , Y. Nakamura, M. Emi, T. Yamamoto, M. Ogawa, T. Mori and K. Matsubara: Primary structure of human salivary alpha-amylase. Gene 41:299-304 ,1986
  8. M. Emi, Y. Nakamura, M. Ogawa, T. Yamamoto, T. Nishide, T. Mori and K. Matsubara: Cloning, characterization and nucleotide sequences of two cDNAs encoding human pancreatic trypsinogens. Gene 41:305-310 ,1986
  9. R. White, Y. Nakamura, C. Julier, A. Silva, P. O'Connell, M. Leppert, M. Lathrop and J.-M. Lalouel: Linkage Maps of Human ChromosomesCurrent Communications in Molecular Biology "DNA Probes" :43-47 ,1986
  10. R. White, M. Leppert, P. O'Connell, Y. Nakamura, C. Julier, S. Woodward, A. Silva, R. Wolff, M. Lathrop and J.-M. Lalouel: Construction of Human Genetic Linkage Maps: I. Progress and perspectives. Cold Spring Harbor Symposia on Quantitative Biology Volume 51: Molecular Biology of Homo Sapiens :29-38 ,1986
  11. Y. Nakamura, T. Sato, M. Emi, A. Miyanohara, T. Nishide and K. Matsubara: Expression of human salivary alpha-amylase gene in Saccharomyces cervisiae (yeast) and its secretion using the mammalian signal sequence. Gene 50:239-245 ,1986
  12. T. Sato , S. Tsunasawa, Y. Nakamura, M. Emi, F. Sakiyama and K. Matsubara: Expression of the human salivary alpha-amylase gene in yeast and characterization of the secreted protein. Gene 50:247-257 ,1986
  13. R. White, M. Leppert, P. O'Connell, Y. Nakamura, S. Woodward, M. Hoff, J. Herbst, M. Dean, G. Vande Woude, M. Lathrop and J.-M. Lalouel: Further linkage data on cystic fibrosis: the Utah study. Am. J. Human Genetics 39:694-698 ,1986

    1987　　↑ページトップへ

  14. Y. Nakamura, M. Leppert, P. O'Connell, Roger Wolff, T. Holm, M. Culver, C. Martin, E. Fujimoto, M. Hoff, E. Kumlin and R. White: Variable number of tandem repeat (VNTR) markers for human gene mapping. Science 235:1616-1622 ,1987
  15. Y. Nakamura, C. Julier, R. Wolff, T. Holm, P. O'Connell, M. Leppert and R. White: Characterization of human "midisatellite" sequence. Nucleic Acid Research 15:2537-2547 ,1987
  16. L. D. Keppen , M. F. Leppert, P. O'Connell, Y. Nakamura, D. Stauffer, M. Lathrop, J-M. Lalouel and R. White: Etiological heterogeneity in X-linked spastic paraplasia. Am. J. Human Genetics 41:933-943 ,1987
  17. R. White, M. Leppert, P. O'Connell, Y. Nakamura, T. Holm, G.M. Lathrop and J-M. Lalouel: Linkage maps of human genes: Acuta Pediatorica Japonica 29:482-488 ,1987
  18. D. Barker , E. Wright, K. Nguyen, L. Cannon, P. Fain, D. Goldger, D. T. Bishop, J. Carey, B. Bety, H. Willard, J. S. Waye, G. Greig, L. Leinward, Y. Nakamura, P. O'Connell, M. Leppert, J.-M. Lalouel, R. White and M. Skolnick: Localization of Von Recklinghausen Neurofibromatosis to the pericentromeric Region of Chromosome 17. Science 236:1100-1102 ,1987
  19. P. O'Connell, G.M. Lathrop, M. Law, M. Leppert, Y. Nakamura, M. Hoff, E. Kumlin, W. Thomas, T. Elsner, L. Ballard, P. Goodman, E. Azen, J.E. Sadler, G.Y. Cai, J.-M. Lalouel and R. White: A primary genetic linkage map for human chromosome 12. Genomics 1:93-102 ,1987
  20. M. Leppert , M. Dobbes, P. Scambler, P. O'Connell, Y. Nakamura, D. Stauffer, S. Woodward, R. Burt, J. Hughes, E. Gardner, M. Lathrop, J. Wasumuth, J.-M. Lalouel, R. White: The gene for familial polyposis coli maps to the long arm of chromosome 5. Science 238:1411-1413 ,1987
  21. R. White, Y. Nakamura, P. O'Connell, M. Leppert, M. Lathrop, J.-M. Lalouel, D. Barker, D. Goldgar, M. Skolnick, C. Mathew and B. Ponder: Tightly linked markers for the neurofibromatosis gene. Genomics 1:364-367 ,1987
  22. P. O'Connell, M. Leppert, Y. Nakamura, M. Dean, M. Park, G.V. Woude, M. Ferrall, B. Wainright, R. Williamson, M. Lathrop, J.-M. Lalouel and R. White: DNA markers for the cystic fibrosis locus. Genetics and Epithelial Cell Dysfunction in Cystic Fibrosis :127-137 Alan R. Liss Inc. ,1987

    1988　　↑ページトップへ

  23. G.M. Lathrop , M. Farrall, P. O'Connell, M. Leppert, Y. Nakamura, N. Lench, H. Kruyer, M. Dean, M. Park, G. Vande Woude, J.-M. Lalouel, R. Williamson, R. White: Refined linkage map of chromosome 7 in the region of cystic fibrosis gene. Am. J. Human Genetics 42:38-44 ,1988
  24. M. Lathrop , Y. Nakamura, P. Cartwright, P. O'Connell, M. Leppert, C. Jones, H. Tateishi, T. Bragg, J.M. Lalouel and R. White: A primary genetic map of markers for human chromosome 10. Genomics 2:157-164 ,1988
  25. C. Larsson , B. Skogseid, K. Obeg, Y. Nakamura, M. Nordenskjold: Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma. Nature 332:85-87 ,1988
  26. Y. Nakamura, M. Lathrop, M. Leppert, M. Dobbes, J. Wasumuth, E. Wolff, M. Carlson, E. Fujimoto, K. Krapcho, S. Woodward, R. Burt, J. Hughes, E. Gardner, J.-M. Lalouel and R. White: Localization of the genetic defect in familial adenomatous polyposis within a small region of chromosome 5. Am. J. Human Genetics 43:638-644 ,1988
  27. Y. Nakamura, M. Lathrop, P. O'Connell, M. Leppert, D. Barker, E. Wright, M. Skolnick, S. Kondoleon, M. Litt, J.-M. Lalouel and R. White: A mapped set of DNA markers for human chromosome 17. Genomics 2:302-307 ,1988
  28. Y. Nakamura, M. Lathrop, P. O'Connell, M. Leppert, J.-M. Lalouel and R. White: A primary map of 10 DNA markers and 2 serological markers for human chromosome 19. Genomics 2:67-71 ,1988
  29. R.A. Lothe , Y. Nakamura, S. Woodward, T. Gedde-Dahl and R. White: VNTR markers show loss of alleles on chromosome 17 and others in human colorectal carcinomas. Cytogenetics Cell Genetics 48:167-169 ,1988
  30. B. Vogelstein , E.R. Fearon, S.R. Hamilton, S. Kern, A.C. Presinger, M. Leppert, Y. Nakamura, R. White, L. Smets and J.L. Bos: Genetic alterations during colorectal tumor development. New Eng. J. Med. 319:525-532 ,1988
  31. S. Chamberlain , J. Shaw, A. Rowland, J. Wallis, S. South, Y. Nakamura, A. von Gabain, M. Farrall and R. Williamson: Mapping of mutation causing Friedrich's ataxia to human chromosome 9. Nature 334:248-250 ,1988
  32. Y. Nakamura, M. Lathrop, P. O'Connell, M. Leppert, J.-M. Lalouel and R. White: A mapped set of markers for human chromosome 15. Genomics 3:342-346 ,1988
  33. Y. Nakamura, M. Carlson, K. Krapcho, M. Kanamori and R. White: A new approach for isolating VNTR markers. Am. J. Human Genetics 43:854-859 ,1988
  34. Y. Nakamura, M. Lathrop, T. Bragg, C. Jones, P. O'Connell, M. Leppert, J.-M. Lalouel and R. White: Short communication an extended genetic linkage map of markers for human chromosome 10. Genomics, 3:389-392, 1988
  35. M. Lathrop , Y. Nakamura, P. O'Connell, M. Leppert, S. Woodward, J.-M. Lalouel and R. White: A mapped set of genetic markers for human chromosome 9. Genomics 3:361-366 ,1988
  36. R.A. Gatti , I. Berkel, E. Border, G. Braedt, P. Charmley, P. Concannon, F. Ersoy, T. Foroud, N.J.G. Jaspers, K. Lange, G.M. Lathrop, M. Leppert, Y. Nakamura, M. Paterson, W. Salser, O. Sanal, W. Shan, J. Silver, R.S. Sparkes, E. Susi, D. Weeks, R. White and F. Yoder: Genetic localization of ataxia-telangiectasia gene to chromosome 11q22.3. Nature 336:577-580 ,1988
  37. P. vanTuinen , W. B. Dobyns, D. C. Rich, K. M. Summers, T. J. Robinson, Y. Nakamura and D. Ledbetter: Molecular detection of microscopic and submicroscopic deletions associated with Miller-Dieker syndrome. Am. J. Human Genetics 43:587-596 ,1988
  38. R. Wolff , Y. Nakamura and R. White: Molecular characterization of a spontaneously generated new allele at a VNTR locus. Genomics 3:347-351 ,1988
  39. P. O'Connell, M. Lathrop, M. Leppert, Y. Nakamura, U. Muller, J.-M. Lalouel and R White: Twelve loci form a continuous linkage map for human chromosome 18. Genomics 3:367-372 ,1988

    1989　　↑ページトップへ

  40. P. O'Connell, G.M. Lathrop, Y. Nakamura, M.L. Leppert, R.H. Ardinger, J.L. Murray, J-M. Lalouel and R. White: Twenty-eight loci form a continuous linkage map of markers for human chromosome 1.Genomics 4:12-20,1989
  41. Y. Nakamura, M. Lathrop, P. O'Connell, M. Leppert, J.M. Lalouel and R. White: Frequent recombination is observed in the distal end of the long arm of chromosome 14. Genomics, 4:76-81, 1989
  42. R. Fujita , A. Seck, Y. Agid, C. Tommasi-Davenas, P. Trouillas, A. J. Driesel, K. Olek, Y. Nakamura, J. L. Mandel and A. Hanauer: Confirmation of linkage of Friedrich ataxia to chromosome 9 and identification of a new closely linked marker. Genomics 4:110-111 ,1989
  43. W. Byerley , J.-M. Lalouel, C. Mellon, Y. Nakamura, P. O'Connell, M. Leppert and R. White: Mapping genes for manic-depression and schizophrenia with DNA markers. Neuroscience 12:46-48 ,1989
  44. R.M. Landsvater, C.P.G. Mathew, B.A. Smith, E.M. Marcus, G.J. te Meerman, C.J.M. Lips, R.A. Geerink, Y. Nakamura, B.A.J. Ponder, C.H.C.M. Buys: Development of multiple endocrine neoplasia type 2A does not involve substantial deletions of chromosome 10. Genomics 4:246-250 ,1989
  45. J. Toguchida , K. Ishizaki, M.S. Sasaki, Y. Nakamura, M. Ikenaga, M. Kato, M. Sugimoto, Y. Kotoura and T. Yamamoto: Preferential mutation of paternally derived RB gene as the initial event in sporadic osteosarcoma. Nature 338:156-158 ,1989
  46. M. Fujimoto , D. Fults, G. Thomas, Y. Nakamura, M. P. Heilbrun, R. White, J. L. Story, S. L. Naylor, K. S. Kagen-Hallet and P. J. Sheridan: Loss of heterozygosity on chromosome 10 in human glioblastoma multiforme. Genomics 4:210-214 ,1989
  47. M. Leppert , E. Anderson, T. Quattlebaum, D. Stauffer, P. O'Connell, Y. Nakamura, J-M. Lalouel and R. White: Mapping of the seizure gene: The gene for benign familial neonatal convulsions maps to human chromosome 20. Nature 337:647-648 ,1989
  48. Y. Nakamura, C.P.G. Mathew, H. Sobol, D.F. Easton, H. Telenius, T. Bragg, K. Chin, J. Clark, C. Jones, G.M. Lonoir, R. White and B.A.J. Ponder: Linked markers flanking the gene for multiple endocrine neoplasia type 2A. Genomics 5:199-203 ,1989
  49. Y. Nakamura, N. Tomita, T. Nishide, M. Emi, A. Horii, M. Ogawa, T. Mori, G. Kosaki, T. Okabe, M. Fujisawa, N. Ohsawa, T. Kameya and K. Matsubara: Production of salivary type alpha-amylase in human lung cancer. Gene 77:107-112 ,1989
  50. K. Tory , H. Brauch, M. Linehan, E. Oldfield, D. Barba, M. Filling-Katz, Y. Nakamura, R. White, B. Seizinger, M.I. Lerman and B. Zbar: Specific genetic change in tumors associated with von Hippel-Lindau disease. J. Natl. Cancer Inst. 81:1097-1101 ,1989
  51. Y. Nakamura, C. Larsson, C. Julier, B. Skogseid, S. Wells, K. Oberg, M. Carlson, P. O'Connell, M. Leppert, J.-M. Lalouel, M. Nordenskjold and R. White: Localization of the genetic defect in multiple endocrine neoplasia type 1 within a small region of chromosome 11. Am. J. Human Genetics 44:571-575 ,1989
  52. L.A. Lothe , S.D. Fossa, A.E. Stenwig, Y. Nakamura, R. White, A.-L. Borresen and A. Brogger: Loss of 3P or 11 alleles is associated with testicular tumors. Genomics 5:134-138 ,1989
  53. B. Vogelstein , E.R. Fearon, S.E. Kern, S.R. Hamilton, A.C. Preisinger, Y. Nakamura and R. White: Allelotype of colorectal carcinomas. Science 244:207-211 ,1989
  54. S.J. Baker , E.R. Fearon, J.M. Nigro, S.R. Hamilton, A.C. Preisinger, J.M. Jessup, P. vanTuinen, D.H. Ledbetter, D.F. Barker, Y. Nakamura, R. White and B. Vogelstein: Chromosome 17 Deletions and p53 mutations in Colorectal Carcinomas. Science 244:217-221 ,1989
  55. P. O'Connell, G.M. Lathrop, Y. Nakamura, M.L. Leppert, J.-M. Lalouel and R. White: Twenty loci form a continuous linkage map of markers for human chromosome 2. Genomics 5:738-745 ,1989
  56. G.M. Lathrop , P. O'Connell, M. Leppert, Y. Nakamura, M. Farrall, L.-C. Tsui, J.-M. Lalouel and R. White: Twenty-five loci form a continuous linkage map of markers for human chromosome 7. Genomics 5:866-873 ,1989
  57. P.G. Ashton-Richkardt , M.G. Dunlop, Y. Nakamura, R.G. Morris, C.A. Purdie, C.M. Steel, H.J. Evans, C.C. Bird and A.H. Wyllie: High frequency of APC loss in sporadic colorectal carcinoma due to breaks clustered in 5q21-22. Oncogene 4:1169-1174 ,1989
  58. Y. Nakamura, M. Leppert, P. O'Connell, M. Lathrop, J.-M. Lalouel and R. White: A genetic linkage map of markers for human chromosome 20. Genomics 5:945-947 ,1989
  59. D. Ledbetter , S. Ledbetter, P. vanTuinen, K. Summers, T. Robinson, Y. Nakamura, R. Wolff, R. White, D. Barker, M. Wallace, F. Collins and W. Dobyns: Molecular dissection of a contiguous gene syndrome: Frequent submicroscopic deletions, evolutionarily conserved sequences, and a hypomethylated "island" in the Miller-Dieker chromosome region. Proc. Natl. Acad. Sci. USA 86:5136-5140 ,1989
  60. H. Sobol , S. Narod, Y. Nakamura, A. Bonue, C. Calmettes, D. Chadenas, G.Charpentier, J. Chatal, N. Delepine, M. Delisle, J. Dupond, P. Gardet, H. Godefroy, P. Guillausseau, C. Sholer, C. Houdent, J. Lalau, G. Mace, C. Parmentier, F. Soubrier, J. Tourniaire and G. Lenoir: Screening for multiple endocrine neoplasia type 2a with DNA-polymorphism analysis. New Eng. J. Med. 321:996-1001 ,1989
  61. E. Friedman , K. Sakaguchi, A. Bale, A. Falchetti, E. Streeten, M. Zimering, L. Wenstein, W. McBride, Y. Nakamura, M. Brandi, J. Norton and G. Aurbach: Clonality of parathyroid tumors in familial multiple endocrine neoplasia type1. New Eng. J. Med. 321:213-218 ,1989
  62. R. Gatti , Y. Nakamura, M. Nussmeier, E. Susi, W. Shan and W. Grody: Informativeness of VNTR genetic markers for detecting chimerism after bone marrow transplantation. Disease Markers 7:105-112 ,1989
  63. T. Sato , H. Uemura, Y. Izumoto, J. Nakao, Y. Nakamura, and K. Matsubara: The conformation of mature human alpha-amylase conditions its secretion from yeast. Gene 83:355-365 ,1989
  64. G.I. Bell , J. Murray, Y. Nakamura, T. Kayano, R. Eddy, Y.-S. Fan, M. Byers and T. Shows: Polymorphic human insulin-responsive glucose-transporter gene on chromosome 17p13. Diabetes 38:1072-1075 ,1989
  65. J. Toguchida , K. Ishizaki, Y. Nakamura, M. Sasaki, M. Ikenaga, M. Kato, M. Sugimoto, Y. Kotoura, and T. Yamamoto: Assignment of common allele loss in osteosarcoma to the subregion 17p13. Cancer Research 49:6247-6251 ,1989
  66. B. Nelkin , Y. Nakamura, R. White, A. Bustros, J. Herman, S. Wells and S. Baylin: Low incidence of loss of chromosome 10 in sporadic and hereditary human medullary thyroid carcinoma. Cancer Research 49:4114-4119 ,1989
  67. R. Korneluk, A. MacKenzie, Y. Nakamura, I. Dube, P. Jacob and A. Hunter: A reordering of human chromosome 19 long-arm DNA markers and identification of markers flanking the myotonic dystrophy locus. Genomics, 5:596-604, 1989
  68. B. Ponder , B. Smith, E. Marcus, Y. Nakamura, R. Landsvater. C. Buys and c. Mathew: Genetic Events in tumorigenesis in multiple endocrine neoplasia type 2. Cancer Cells 7:219-221 ,1989
  69. M. El-Azouzi , R. Chung, G. Farmer, R. Martuza, P. Black, G. Rouleau, C. Hettlich, E. Hedley-Whyte, N. Zervas, K. Panagopoulos, Y. Nakamura, J. Gusella and B. Seizinger:Loss of distinct regions on the short arm of chromosome 17 associated with tumorigenesis of human astrocytomas. Proc. Natl. Acad. Sci. USA 86:7186-7190 ,1989
  70. S.J. Odelberg, R. Plaetke, J.R. Eldridge, L. Ballard, P. O'Connell, Y. Nakamura, M. Leppert, J.-M. Lalouel and R. White: Characterization of VNTR loci by high-resolution agarose gel electrophoresis: Implications for parentage testing and forensic individualization. Genomics 5:915-924,1989
  71. S.A. Narod , H. Sobol, Y. Nakamura, C. Calmettes, J.-L. Baulieu, J.-C. Bigorgne, G. Chabrier, J. Couette, J.-L. Gennes, J. Duprey, P. Gardet, P.-J. Guillausseau, D. Guilloteau, C. Houdent, J. Lefebvre, E. Modigliani, C. Parmentier, M. Pugeat, C. Siame, J. Tourniaire, J.-C. Vandroux, J.-M. Vinot, G.M. Lenoir: Linkage analysis of hereditary thyroid carcinoma with and without pheochromocytoma. Human Genetics 83:353-358 ,1989
  72. D. Fults , R. Tippets, G.A. Thomas, Y. Nakamura and R. White: Loss of heterozygosity for loci on chromosome 17p in human malignant astrocytoma. Cancer Research 49:6572-6577 ,1989
  73. D. Fults , P.F. Maness, Y. Nakamura and R. White: The N-ras oncogene is activated in a human medulloblastoma cell line. Brain Research 503:281-287 ,1989
  74. S. Kern , E. Fearon, K.W.F. Tersmette, J.P. Enterline, M. Leppert, Y. Nakamura, R. White, B. Vogelstein and S. Hamilton: Allelic loss in colorectal carcinoma. JAMA 261:3099-3103 ,1989
  75. R. White, J.-M. Lalouel, M. Leppert, M. Lathrop, Y. Nakamura and P. O'Connell: Linkage maps of human chromosomes. Genome 31:1066-1072 ,1989

    1990　　↑ページトップへ

  76. H. Telenius , C.P.G. Mathew, Y. Nakamura, D.F. Easton, J. Clark, H.P.N. Neumann, W.H. Ziegler, A. Schinzel and B.A.J. Ponder: Application of linked DNA markers to screening families with multiple endocrine neoplasia type 2A. Eur. J. Sug. Oncology 16:134-140 ,1990
  77. M.H. Hofker , S. Smith, Y. Nakamura, I. Teshima, R. White and D. Cox: Physical mapping of probes within 14q32, a subtelomeric region showing a high recombination frequency. Genomics 6:33-38 ,1990
  78. M. Smith , S. Malley, R. Cantor, M. Pandolfo, M. Gomes, R. Baumann, P. Flodman, K. Yoshiyama, Y. Nakamura, C. Julier, K. Dumars, J. Haines, J. Trofatter, M.A. Spence, D. Weeks and M. Conneally: Mapping of a gene determining tuberous sclerosis to human chromosome 11q14-11q23. Genomics 6:105-114 ,1990
  79. C. Julier , Y. Nakamura, M. Lathrop, P. O'Connell, M. Leppert, T. Mohandas, J.-M. Lalouel and R. White: A primary map of 24 loci on human chromosome 16. Genomics 6:419-427 ,1990
  80. R.L. White , J.-M. Lauloel, Y. Nakamura, H.D.-Keller, P Green, D.W. Bowden, C.G.P. Mathew, D.F. Easton, E.B. Robson, N.E. Morton, J.F.Gusella, J.L. Haines, A.E. Retief, K.K. Kidd, J.C. Murray, G.M. Lathrop and H.M. Cann: The CEPH consortium primary linkage map of human chromosome 10. Genomics 6:393-412 ,1990
  81. M. Leppert , R. Burt, J. Hughes, W. Samowitz, Y. Nakamura, S. Woodward, E. Gardner, J. Lalouel and R. White: Genetic analysis of an inherited predisposition to colon cancer in a family with a variable number of adenomatous polyps. New Eng. J. Med. 322:904-908 ,1990
  82. P. Patel, B. Franco, C. Garcia, S. A. Slaugenhaupt, Y. Nakamura, D. Ledbetter, A. Chakravarti and J. R. Lapski: Genetic mapping of autosomal dominant Charcot-Marie-Tooth disease in a large French-Canadian kindred: Identification of new linked markers on chromosome 17. Am. J. Human Genetics 46:801-809 ,1990
  83. J.C. Murray , D.Y. Nishimura, K.H. Buetow, H.H. Ardinger, M.A. Spence, R.S. Sparkes, R.E. Falk, P.M. Falk, R.J. Gardner, E.M. Harkness, L.P. Glinski, R.M. Pauli, Y. Nakamura, P.P. Green and A. Schinzel: Linkage of an autosomal dominant clefting syndrome (Van der Woude) to loci on chromosome 1q. Am. J. Human Genetics 46:486-491 ,1990
  84. R. White, Y. Nakamura, P. O'Connell, M. Leppert and J-M. Lalouel: Mapping genetic defects by linkage studies in families: A strategy for finding genes associated with cancer syndromes. Genetic Mechanisms in Carcinogenesis and Tumor Progression :153-161 ,1990
  85. G.G. Germino , N.J. Barton, J. Lamb, K.R. Higgs, P. Harris, G.H. Xiao, G. Scherer, Y. Nakamura and S.T. Reeder: Identification of a locus which shows no genetic recombination with the autosomal dominant polycystic kidney disease gene on chromosome 16. Am. J. Human Genetics 46:925-933 ,1990
  86. J. Groden , Y. Nakamura and J. German: Bloom syndrome: Molecular evidence that homologous recombination occurs in proliferating somatic cells. Proc. Natl. Acad. Sci. USA 87:4315-4319 ,1990
  87. K. Ishizaki , M. Oshimura, M.S. Sasaki, Y. Nakamura and M. Ikenaga: Human chromosome 9 can complement UV sensitivity of xeroderma pigmentosum group a cells. Mutation Research 235:209-215 ,1990
  88. C.G.P. Mathew , W. Wakiling, E. Jones, D. Easton, R. Fisher, C. Strong, B. Smith, K. Chin, P. Little, Y. Nakamura, T.B. Shows, C. Jones, P.J. Goodfellow, S. Povey and B.A.J. Ponder:Regional localization of polymorphic markers on chromosome 10 by physical and genetic mapping. Annals Human Genetics 54:121-129 ,1990
  89. C. Julier , B. Gouyon, M. Jeorges, J.L. Guenet, Y. Nakamura, P. Avner and M. Lathrop: Minisatellite linkage maps in the mouse by cross-hybridization with human probes containing tandem repeats. Proc. Natl. Acad. Sci. USA 87:4585-4589 ,1990
  90. G.M. Petersen, J. Brown, X. Bu, R.S. Sparkers and Y. Nakamura: Genetic linkage study of juvenile polyposis: Preliminary analysis. Hereditary colorectal cancer, :431-432, 1990
  91. M. Leppert, Y. Nakamura, R. Burt, J.P. Hughes, W. Samowitz, S. Woodward, E. Gardner, J.-M. Lalouel and R. White: Eldon Gardner memorial lecture: Genetic mapping and allelic heterogeneity of the familial polyposis gene. Hereditary colorectal cancer :27-36, 1990
  92. A.H. Wyllie , P. Ashton-Rickardt, M.G. Dunlop, Y. Nakamura, J. Piris, C. Purdie, C.M. Steel and C.C. Bird: Status of the APC gene in familial and sporadic colorectal tumours as determined by closely flanking markers. Hereditary colorectal cancer :453-456 ,1990
  93. Y. Nakamura, J. Wasmuth and R. White: Searching the gene responsible to familial polyposis coli(FAP). Hereditary colorectal cancer :469-472 ,1990
  94. Y. Nakamura, R.L. White: Summary of chapter 7: Cytomolecular aspects of colorectal cancer. Hereditary colorectal cancer :475-476 ,1990
  95. R. White, M. Leppert, Y. Nakamura, P. O'Connell, M. Lathrop and J.-M. Lalouel: Mapping genes that cause disease. The cellular and molecular biology of human carcinogenesis :61-74 ,1990
  96. Y. Nakamura, Clinical application restriction fragment length polymorphisms (RFLPs). Automation and new technology in the clinical laboratory :131-137, 1990
  97. C. Julier , Y. Nakamura, M. Lathrop, P. O'Connell, M. Leppert, M. Litt, T. Mohandas, J.-M. Lalouel and R. White: A detailed genetic map of the long arm of chromosome 11. Genomics 7:335-345, 1990
  98. H. Shibuya , M. Yoneyama, Y. Nakamura, H. Harada, M. Hatakeyama, S. Minamoto, T. Kono, T. Doi, R. White, and T. Taniguchi: The human interleukin-2 receptor bete-chain gene: genomic organization, promoter analysis and chromosomal assignment. Nucleic Acid Research 18:3697-3703 ,1990
  99. K.H. Buetow , D. Nishimura, P. Green, Y. Nakamura, O. Jiang and J.C. Murray: A detailed multipoint gene map of chromosome 1q. Genomics 8:13-21, 1990
  100. K. Kasai , Y. Nakamura and R. White: Amplification of a VNTR locus (pMCT118) by the polymerase chain reaction (PCR) and its application to forensic science. J. Forensic Sci. 35:1196-1200, 1990
  101. D.M. Eccles , G. Cranston, C.M. Steel, Y. Nakamura, and R.C.F. Leonard: Allele losses on chromosome 17 in human epithelial ovarian carcinoma. Oncogene 5:1599-1601, 1990
  102. T. Sato , A. Tanigami, K. Yamakawa, F. Akiyama, F. Kasumi, G. Sakamoto and Y. Nakamura: Allelotype of breast cancer: Cumulative allele losses promote tumor progression in primary breast cancer. Cancer Research 50:7184-7189, 1990
  103. M. Miyaki, M.Seki, M. Okamoto, A. Yamanaka, Y. Maeda, K. Tanaka, R. Kikuchi, T. Iwama, T. Ikeuchi, A. Tonomura, Y. Nakamura, R. White, Y. Miki, J. Utsunomiya and M. Koike: Genetic changes and histopathological types in colorectal tumors from patients with familial adenomatous polyposis. Cancer Research 50:7166-7173, 1990
  104. J.R. Batanian, S. Ledbetter, R. Wolff, Y. Nakamura, R. White, W. Dobyns and D. Ledbetter: Rapid diagnosis of Miller-Dieker syndrome and isolated lissencephaly sequence by the polymerase chain reaction. Human Genetics 85:555-559, 1990
  105. M.G. Dunlop , A.W. Wyllie, Y. Nakamura, C.M. Steel, H.J. Evans, R. White and C.C. Bird: Genetic linkage map of six polymorphic DNA markers around the gene for familial adenomatous polyposis on chromosome 5. Am. J. Human Genetics 47:982-987, 1990
  106. M. Okamoto , C. Sato, Y. Kohno, T. Mori, T. Iwama, A. Tonomura, Y. Miki, J. Utsunomiya, Y. Nakamura, R. White and M. Miyaki: Loss of alleles on the long arm of chromosome 5 in colorectal and desmoid tumors from patients with familial adenomatous polyposis. Human Genetics 85:595-599, 1990
  107. P. Patel, S. O'Rahilly, V. Buckle, Y. Nakamura, R.C. Turner and J.S. Wainscoat: Chromosome 11 allele loss in sporadic insulinoma. J. Clin. Pathol. 43:377-378 ,1990
  108. C. Coles , A.M. Thompson, P.A. Elder, B.B. Cohen, I.M. Mackenzie, G. Cranston, U. Chetty, J. Mackay, M. Macdonald, Y. Nakamura, B. Hoyheim and C.M. Steel: Evidence implicating at least two genes on chromosome 17p in breast carcinogenesis. Lancet 336:761-763 ,1990

    1991　　↑ページトップへ

  109. T. Tokino , E. Takahashi, M. Mori, A. Tanigami, T. Glaser, J.W. Park, C. Jones, T. Hori and Y. Nakamura: Isolation and mapping of 62 new RFLP markers on human chromosome 11. Am. J. Human Genetics 48:258-268 ,1991
  110. C.G.P. Mathew , D.F. Easton, Y. Nakamura and B.A.J. Ponder: Presymptomatic screening for multiple endocrine neoplasia type 2A with linked DNA markers. Lancet 337:7-12,1991
  111. M. Fujimori , T. Tokino, O. Hino, T. Kitagawa, T. Imamura, E. Okamoto, M. Mitsunobu, T. Ishikawa, H. Nakagama, H. Harada, M. Yagura, K. Matsubara and Y. Nakamura: Allelotype study of primary hepatocellular carcinoma. Cancer Research 51:89-93 ,1991
  112. R. Morita , J. Ishikawa, M. Tsutsumi, K. Hikiji, Y. Tsukada, S. Kamidono, S. Maeda and Y. Nakamura: Allelotype of renal cell carcinoma. Cancer Research 51:820-823 ,1991
  113. K. Yamakawa, E. Takahashi, H. Saito, T. Sato, M. Oshimura, T. Hori and Y. Nakamura: Isolation and mapping of 75 new DNA markers on human chromosome 3. Genomics 9:536-543 ,1991
  114. K.W. Kinzler, M.C. Nilbert, B. Vogelstein, T.M. Bryan, D.B. Levy, K.J. Smith, A.C. Preisinger, S.R. Hamilton, P. Hedge, A. Merkham, M. Carlson, G. Joslyn, J. Groden, R. White, Y. Miki, I. Nishisho and Y. Nakamura: Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science 251:1366-1370 ,1991
  115. T. Sano, T. Tsujino, K. Yoshida, H. Nakayama, K. Haruma, H. Ito, Y. Nakamura, G. Kajiyama and E. Tahara: Frequent loss of heterozygosity on chromosome 1q, 5q and 17p in human gastric carcinomas. Cancer Research 51:2926-2931 ,1991
  116. G. Petersen , J. Slack and Y. Nakamura: Screening guidelines and premorbid diagnosis of familial adenomatous polyposis using linkage. Gastroenterology 100:1658-1664 ,1991
  117. K.H. Buetow , R. Shiang, P. Yang, Y. Nakamura, G.M. Lathrop, R. White, J.J. Wasmuth, S. Wood, L.D. Berdahl, N.J. Leysens, T.M. Ritty, M.E. Wise, and J.C. Murray: A detailed multipoint map of human chromosome 4 provides evidence for linkage heterogeneity and position-specific recombination rates. Am. J. Human Genetics 48:911-925 ,1991
  118. P.G. Ashton-Richkardt , A.H. Wyllie, C.C. Bird, M.G.Dunlop, C.M. Steel, R.G. Morris, J. Piris, P. Romanowski, R.Wood, R. White, and Y. Nakamura: MCC, a candidate familial polyposis gene in 5q.21, shows frequent allele loss in colorectal and lung cancer. Oncogene 6:1881-1886 ,1991
  119. Y. Miki, I. Nishisho, Y. Miyoshi, A. Horii, H. Ando, T. Nakajima, J. Utsunomiya and Y. Nakamura: Frequent loss of heterozygosity at the MCC locus on chromosome 5q21-22 in sporadic colorectal carcinomas. Jpn. J. Cancer Research 82:1003-1007 ,1991
  120. K. Yamakawa, R. Morita, E. Takahashi, T. Hori, J. Ishikawa, and Y. Nakamura: A detailed deletion mapping of the short arm of chromosome 3 in sporadic renal cell carcinoma. Cancer Research 51:4707-4711 ,1991
  121. T. Sato , H. Saito, R. Morita, S. Koi, Je H. Lee, and Y. Nakamura: Allelotype of human ovarian cancer. Cancer Research 51:5118-5121 ,1991
  122. K. Yamakawa, R. Morita, E. Takahashi, M. Lathrop, and Y. Nakamura: A genetic linkage map of 41 RFLP markers for human chromosome 3. Genomics 11:565-572 ,1991
  123. K.W. Kinzler , M.C. Nilbert, L. Su, B. Vogelstein, T.M. Bryan, D.B. Levy, K.J. Smith, A.C. Preisinger, P. Hedge, D. McKechnie, R. Finniear, A. Markham, J. Groffen, M.S. Boguski, S.F. Alschul, A. Horii, H. Ando, Y. Miyoshi, Y. Miki, I. Nishisho, Y. Nakamura: Identification of FAP locus genes from chromosome 5q21. Science 253:661-665 ,1991
  124. I. Nishisho , Y. Nakamura, Y. Miyoshi, Y. Miki, H. Ando, A. Horii, K. Koyama, J. Utsunomiya, S. Baba, P. Hedge, A. Markham, A.J. Krush, G. Petersen, S.R. Hamilton, M.C. Nilbert, D.B. Levy, T.M. Bryan, A.C. Preisinger, K.J. Smith, L. Su, K.W. Kinzler, and B. Vogelstein: Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science 253:665-669 ,1991
  125. R. Morita , S. Saito, J. Ishikawa, O. Ogawa, O. Yoshida, K. Yamakawa, Y. Nakamura: Common regions of deletion on chromosomes 5q, 6q, and 10q in renal cell carcinoma. Cancer Research 51:5817-5820 ,1991
  126. S. Itoh , H. Harada, Y. Nakamura, R. White, T. Taniguchi: Assignment of the human interferon regulatory factor-1 (IRF1) gene to chromosome 5q23-q31. Genomics 10:1097-1099 ,1991
  127. T. Sato , F. Akiyama, G. Sakamoto, F. Kasumi, Y. Nakamura: Accumulation of genetic alterations and progression of primary breast cancer. Cancer Research 51:5794-5799 ,1991
  128. M. Janson , C. Larsson, B. Werelius, C Jones, T. Glaser, Y. Nakamura, C. Peter Jones, M. Nordenskjold: Detailed physical map of human chromosomal region 11q12-13 shows high meiotic recombination rate around the MEN1 locus. Proc. Natl. Acad. Sci. USA 88:10609-10613 ,1991

    1992　　↑ページトップへ

  129. Y. Miki, I. Nishisho, Y. Miyoshi, J. Utsunomiya, Y. Nakamura: An interstitial loss of the same region of chromosome 5q in multiple adenomas and a carcinoma derived from adenomatous polyposis coli (APC) patient. Genes Chromosomes and Cancer 4:81-83 ,1992
  130. M. Thangavelu , W. Neuman, R. Espinosa, Y. Nakamura, C.A. Westbrook, M. M. Le Beau: A physical and genetic linkage map of the distal long arm of chromosome 5. Cytogenetics Cell Genetics 59:27-30 ,1992
  131. S. Saito, K. Okui, T. Tokino, M. Oshimura, Y. Nakamura: Isolation and mapping of 68 RFLP markers on human chromosome 6. Am. J. Human Genetics 50:56-64 ,1992
  132. A. Tanigami , T. Tokino, S. Takiguchi, M. Mori, T. Glaser, J.W. Park, C. Jones, Y. Nakamura, Mapping of 262 DNA markers into 24 intervals on human chromosome 11. Am. J. Human Genetics 50:65-70 ,1992
  133. T. Tokino , T. Imai, A. Tanigami, S. Takiguchi, Y. Nakamura: Physical mapping of a 950-kb region surrounding a locus (D10S102) tightly linked to the MEN2A gene. Genomics 12:394-400 ,1992
  134. T. Tokino , S. Takiguchi, A. Tanigami, T. Bragg, C. Jones, Y. Nakamura: 31 new RFLP systems detected by 24 DNA markers on human chromosome 10. Genomics 12:401-402 ,1992
  135. M. Fujimori , S. A. Wells Jr, Y. Nakamura: Fine-scale mapping of the gene responsible for multiple endocrine neoplasia type 1 (MEN). Am. J. Human Genetics 50:399-403 ,1992
  136. K. Hibi , T. Takahashi, K. Yamakawa, R. Ueda, Y. Sekido, Y. Ariyoshi, M. Suyama, H. Takagi, Y. Nakamura, T. Takahashi: Three distinct regions involved in 3p deletion in human lung cancer. Oncogene 7:445-449 ,1992
  137. Y. Miyoshi, I. Nishisho, Y. Miki, T. Mori, K. Kinzler, B. Vogelstein, Y. Nakamura: Insertion/deletion polymorphism and other restriction fragment length polymorphisms in the MCC gene. Jpn. J. Cancer Research 83:10-14,1992
  138. S. Yokoyama , K. Yamakawa, E. Tsuchiya, M. Murata, S. Sakiyama, Y. Nakamura: Deletion mapping on the short arm of chromosome 3 in squamous cell carcinoma and adenocarcinoma of the lung. Cancer Research 52:873-877 ,1992
  139. Y. Miki, I. Nishisho, A. Horii, Y. Miyoshi, J. Utsunomiya, K. Kinzler, B. Vogelstein. Y. Nakamura: Disruption of the APC gene by retrotransposal insertion of L1 sequence in a colon cancer. Cancer Research 52:643-645 ,1992
  140. M. Mori , T. Tokino, A. Yanagisawa, M. Kanamori, Y. Kato, Y. Nakamura: Correlation of chromosome 11q13 amplification with prognosis of patients with esophageal carcinomas. Europian Journal of Cancer 28:755-758 ,1992
  141. A. Tanigami , T. Tokino, K. Takita, S. Takiguchi, Y. Nakamura: A 14-mb physical map of the region at chromosome 11q13 harboring the MEN1 locus and the tumor amplicon region (TAR). Genomics 13:16-20 ,1992
  142. T. Hori , E. Takahashi, A. Tanigami, T. Tokino, Y. Nakamura: A high-resolution cytogenetic map of 168 cosmid DNA markers for human chromosome 11. Genomics 13:129-133 ,1992
  143. H. Takayama , T. Suzuki, H. Mugishima, T. Fujisawa, M. Ookuni, M. Schwab, M. Gehring, Y. Nakamura, T. Sugimura, M. Terada and J. Yokota: Deletion mapping of chromosome 14q and 1p in human neuroblastoma. Oncogene 7:1185-1190 ,1992
  144. Y. Miyoshi, H. Ando, H. Nagase, I. Nishisho, A. Horii, Y. Miki, T. Mori, J. Utsunomiya, S. Baba, G. Petersen, S.R. Hamilton, K.W. Kinzler, B. Vogelstein, Y. Nakamura: Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients. Proc. Natl. Acad. Sci. USA 89:4452-4456 ,1992
  145. M.H. Jones, Y. Nakamura: Detection of loss of heterozygosity at the human p53 locus using a dinucleotide repeat polymorphism. Genes Chromosomes and Cancer 5:89-90 ,1992
  146. A. Tanigami , T. Tokino, K. Takita, M. Ueda, F. Kasumi, Y. Nakamura: Detailed analysis of an amplified region at chromosome 11q13 in malignant tumors. Genomics 13:21-24 ,1992
  147. T. Yamaguchi, J. Toguchida, Y. Nakamura, T. Yamamuro, Y. Kotoura, N. Takada, N. Kawaguchi, Y. Kaneko, M. S. Sasaki, K. Ishizaki: Allelotype analysis in osteosarcomas ; Frequent allele loss on 3q, 13q, 17p and 18q. Cancer Research 52:2419-2423 ,1992
  148. T. Sato , H. Saito, J. Swensen, A. Olifant, C. Wood, D. Danner, T. Sakamoto, K. Takita, F. Kasumi, Y. Miki, M. Skolnick, Y. Nakamura: The human prohibitin gene, located on chromosome 17q21, is mutated in sporadic breast cancer. Cancer Research 52:1643-1646 ,1992
  149. M.H. Jones, Y. Nakamura: Deletion mapping of chromosome 3p in female genital tract malignancies using microsatellite polymorphisms. Oncogene 7:1631-1634 ,1992
  150. E. Tsuchiya, Y. Nakamura, S. Weng, K. Nakagawa, S. Tsuchiya, H. Sugano and T. Kitagawa: Allelotype of non-small cell lung carcinoma-comparison between loss of heterozygosity in squamous cell carcinoma and adenocarcinoma. Cancer Research, 52:2478-2481, 1992
  151. M.H. Jones, K. Yamakawa and Y. Nakamura: Isolation and characterization of 19 dinucleotide-repeat polymorphisms on chromosome 3p. Human Molecular Genetics 1:131-134 ,1992
  152. J. Utsunomiya , K. Tamura, R. Yoshikawa, Y. Miki, M. Miyaki, and Y. Nakamura: New insights into familial adenomatous polyposis. Recent Progress in Colorectal Cancer: Biology and Management of High Risk Groups. :203-210 ,1992
  153. E. Takahashi , K. Yamakawa, Y. Nakamura and T. Hori: A high resolution cytogenetic map of human chromosome 3: localization of 292 new cosmid markers by a direct mapping system with fluorescence in situ hybridization. Genomics 13:1047-1055 ,1992
  154. D. Cherif , H. Der-Sarkissian, J. Derre, T. Tokino, Y. Nakamura and R. Berger: The 11q23 breakpoint in acute leukemia with t(11;19)(q23;p13) is distal to those of t(4;11),t(6;11) and t(9;11). Genes Chromosomes and Cancer 4:107-112 ,1992
  155. K. Takita, T. Sato, M. Miyagi, M. Watatani, F. Akiyama, G. Sakamoto, F. Kasumi, R. Abe, and Y. Nakamura: Correlation of loss of alleles on the short arms of chromosome 11 and 17 with metastasis of primary breast cancer to lymphnodes. Cancer Research 52:3914-3917 ,1992
  156. M. Jones, Y. Nakamura: Somatic mutations at CA-repeat loci. Human Mutation 1:224-228 ,1992
  157. H. Nagase , Y. Miyoshi, A. Horii, T. Aoki, M. Ogawa, J. Utsunomiya, S. Baba, T. Sasazuki and Y. Nakamura: Correlation between the location of germ-line mutations in the APC gene and the number of colorectal polyps in familial adenomatous polyposis (FAP) patients. Cancer Research 52:4055-4057 ,1992
  158. A. Horii , S. Nakatsuru, Y. Miyoshi, S. Ichii, H. Nagase, Y. Kato, A. Yanagisawa and Y. Nakamura: The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer. Cancer Research 52:3231-3233 ,1992
  159. K. Takita, A. Tanigami, T. Tokino, C. Jones and Y. Nakamura: Identification of 57 conventional RFLP and 6 VNTR systems with 32 DNA clones on chromosome 11p15. Genomics 13:1296-1299 ,1992
  160. M. Peter , J. Michon, P. Vielh, S. Neuenschwander, Y. Nakamura, E. Sonsino, J.-M. Zucker, G. Vergnaud, G. Thomas and O. Delattre: PCR assay for chromosome 1p deletion in small neuroblastoma samples. Int. J. Cancer ,1992
  161. M. Emi, K. Koyama, K. Okui, E. Takahashi, M. Oshimura and Y. Nakamura: Isolation and mapping of 88 new RFLP markers on human chromosome 8. Genomics 13:1261-1266 ,1992
  162. Y. Miyoshi, H. Nagase, H. Ando, A. Horii, S. Ichii, S. Nakatsuru, T. Aoki, Y. Miki, T. Mori and Y. Nakamura: Somatic mutation of the APC gene in colorectal tumors: mutation cluster region in the APC gene. Human Molecular Genetics 1:229-233 ,1992
  163. K. Yamakawa, E. Takahashi, M. Murata, K. Okui, S. Yokoyama and Y. Nakamura: Detailed mapping around the breakpoint of (3;8) translocation in familial renal cell carcinoma and FRA3B. Genomics 14:412-416 ,1992
  164. K. Tsukamoto , T. Tohma, T. Ohta, K. Yamakawa, Y. Fukushima, Y. Nakamura and N. Niikawa: Cloning and characterization of the inversion breakpoint at chromosome 2q35 in a patient with Waardenburg syndrome type I. Human Molecular Genetics 1:315-318 ,1992
  165. M. Emi, Y. Fujiwara, T. Nakajima, E. Tsuchiya, H. Tsuda, S. Hirohashi, M. Miyaki and Y. Nakamura: Frequent loss of heterozygosity for loci on chromosome 8p in hepatocellular carcinoma, colorectal cancer, and lung cancer. Cancer Research 52:5368-5372 ,1992
  166. C. Larsson , J. Shepherd, Y. Nakamura, C. Blomberg, G. Weber, B. Werelius, N. Hayward, B. Teh, T. Tokino, B. Seizinger, B. Skogseid, K. Oberg, and M. Nordenskjold: Predictive testing for multiple endocrine neoplasia type 1 using DNA polymorphisms. J. Clin. Invest. 89:1344-1349 ,1992
  167. W. Cookson , R.P. Young, A.J. Sandford, M.F. Moffatt, T. Shirakawa, P.A. Sharp, J.A. Faux, C. Julier, R.A. Wells, P.N. Le Souef, Y. Nakamura, G.M. Lathrop and J.M. Hopkin: Maternal inheritance of atopy (Allergic asthma and rhinitis) on chromosome 11q. Lancet 340:381-384 ,1992
  168. S. Ichii, A. Horii, S. Nakatsuru, J. Furuyama, J. Utsunomiya and Y. Nakamura: Inactivation of both APC alleles in an early stage of colon adenomas in a patient with familial adenomatous polyposis (FAP). Human Molecular Genetics 1:387-390 ,1992
  169. Y. Nakamura, I. Nishisho, K. Kinzler, B. Vogelstein, Y. Miyoshi, Y. Miki, H. Ando, A. Horii, and H. Nagase: Mutations of the adenomatous polyposis coli gene in familial polyposis coli patients and sporadic colorectal tumors. Multistage carcinogenesis :285-292 ,1992
  170. S. Saito, H. Saito, S. Koi, S. Sagae, R. Kudo, J. Saito, K. Noda and Y. Nakamura: Fine-scale deletion mapping of the distal long arm of chromosome 6 in 70 human ovarian cancers. Cancer Research 52:5815-5817 ,1992
  171. NIH, CEPH Collaborative Mapping Group. A comprehensive genetic linkage map of the human genome. Science 258:67-86 ,1992
  172. A. Horii , S. Nakatsuru, Y. Miyoshi, S. Ichii, H. Nagase, H. Ando, A. Yanagisawa, E. Tsuchiya, Y. Kato, and Y. Nakamura: Frequent Somatic mutation of the APC gene in human pancreatic cancer. Cancer Research 52:6696-6698 ,1992
  173. M. Shohat , X. Bu, T. Shohat, N. Fischel-Ghodsian, N. Magal, Y. Nakamura, A.D. Schwabe, M. Schlezinger, Y. Danon, J.I. Rotter: The gene for familial mediterranean fever in both Armenians and non-ashkenazi Jews is linked to the a-globin complex on 16p. Am. J. Human Genetics 51:1349-1354 ,1992
  174. M. Miyagi, J. Inazawa, K. Takita, and Y. Nakamura: Cloning and characterization of an interstitial deletion at chromosome 11p15 in a sporadic breast cancer. Human Molecular Genetics, 1:705-708, 1992
  175. S. Nakatsuru , A. Yanagisawa, S. Ichii, E. Tahara, Y. Kato, Y. Nakamura, and A. Horii: Somatic mutation of the APC gene in gastric cancer: Frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma. Human Molecular Genetics 1:559-563 ,1992
  176. S. Nagafuchi , Y. Nakahori, Y. Nakamura, S.B. England, T. Tamura, H. Numabe, and Y. Nakagome: Localization of 24 cosmid clones on the human Y chromosome. Jpn. J. Human Genetics 37:307-310 ,1992
  177. H. Nagase , Y. Miyoshi, A. Horii, T. Aoki, G.M. Petersen, B. Vogelstein, E. Maher, M. Ogawa, J. Utsunomiya, S. Baba, and Y. Nakamura: Screening for Germ-Line Mutations in Familial Adenomatous Polyposis (FAP) Patients: 61 new patients and a summary of 150 Unrelated Patients. Human Mutation 1:467-473 ,1992
  178. Y. Nakamura, I. Nishisho, K.W. Kinzler, B. Vogelstein, Y. Miyoshi, Y. Miki, H. Ando, and A. Horii: Mutations of the APC (Adenomatous Polyposis Coli) gene in FAP (Familial Polyposis Coli) patients and in sporadic colorectal tumors. Tohoku J. Exp. med. 168:141-147 ,1992
  179. S. Olschwang, R. Fabre, P. Laurentpuig, A. Vassal, B. Hamelin, Y. Nakamura, and G. Thomas: Detection by dgge of a new polymorphism closely linked to the adenomatous polyposis-coli region. Human Genetics, 88:658-660, 1992

    1993　　↑ページトップへ

  180. S. Saito, Y. Nakamura: A genetic linkage map with 16 RFLP loci on the distal long arm of human chromosome 6. Genomics 15:103-106 ,1993
  181. K. Yamakawa, Ta. Takahashi, Y. Horio, Y. Murata, E. Takahashi, K. Hibi, S. Yokoyama, R. Ueda, To. Takahashi and Y. Nakamura: Frequent homozygous deletion in lung cancer cell lines detected by a DNA marker located at 3p21.3-p22. Oncogene 8:327-330 ,1993
  182. E. Arai , T. Tokino, T. Imai, J. Inazawa, Y. Ikeuchi, A. Tonomura, and Y. Nakamura: Mapping the breakpoint of a constitutional translocation on chromosome 22 in a patient with NF2. Genes Chromosomes and Cancer 6:235-238 ,1993
  183. W. Neuman , C. Westbrook, M. Dixon, R. Espinosa, Y. Patel, Y. Nakamura, B. Weiffenbach, and M. LeBeau. Physical localization of 70 polymorphic markers to human chromosome 5 by fluorescence in situ hybridization. Cytogenetics Cell Genetics 62:207-210 ,1993
  184. Y. Fujiwara, M. Monden, T. Mori, Y. Nakamura, and Mitsuru Emi: Frequent multiplication of the long arm of chromosome 8 in hepatocellular carcinoma. Cancer Research 53:857-860 ,1993
  185. H. Ando , Y. Miyoshi, H. Nagase, S. Baba, and Y. Nakamura: Detection of twelve germ-line mutations in the adenomatous polyposis coli (APC) gene by PCR. Gastroenterology 104:989-993 ,1993
  186. G.M. Petersen , C. Francomano, K. Kinzler, A. Krush, and Y. Nakamura: Presymptomatic direct detection of APC gene mutation in familial adenomatous polyposis. Human Genetics 91:307-311 ,1993
  187. M. Emi, Y. Fujiwara, and Y. Nakamura: A primary genetic linkage map of polymorphic loci for the short arm of human chromosome 8. Genomics 15:530-534 ,1993
  188. A. Horii , S. Nakatsuru, S. Ichii, H. Nagase, and Y. Nakamura: Multiple forms of the APC gene transcripts and their tissue-specific expression. Human Molecular Genetics 2:283-287 ,1993
  189. K. Koyama , M. Emi, and Y. Nakamura: The Cell Adhesion Regulator (CAR) gene: TaqI and insertion/deletion polymorphisms, and regional assignment to periteromeric region of 16q by linkage analysis. Genomics 16:264-265 ,1993
  190. S. Takeda, S. Ichii and Y. Nakamura: Detection of K-ras mutation in sputum by mutant-allele-specific amplification (MASA). Human Mutation 2:112-117 ,1993
  191. H. Ohata, M. Emi, Y. Fujiwara, K. Higashino, K. Nakagawa, R. Futagami, E. Tsuchiya, and Y. Nakamura: Deletion mapping of the short arm of chromosome 8 in non-small cell lung carcinoma. Genes Chromosomes and Cancer 7:85-88 ,1993
  192. Y. Nakamura, The role of the APC (adenomatous polyposis coli) gene in human cancers (review article). Advance in Cancer Genetics 62:65-87 ,1993
  193. S. Takiguchi , S. Saito and Y. Nakamura: Characterization of four VNTR loci on human chromosome 6. Mammalian Genome 4:21-24 ,1993
  194. Y. Fujiwara, M. Emi, H. Ohata, Y. Kato, T. Nakajima, T. Mori, and Y. Nakamura: Evidence for a presence of two tumor suppressor genes on chromosome 8p for colorectal carcinoma. Cancer Research 53:1172-1174 ,1993
  195. J. Melki, P. Burlet, O. Clermont, F. Pascal, B. Paul, S. Abdelhak, R. Sherrington, H. Gurling, Y. Nakamura, J. Weissenbach, M. Lathrop and A. Munnich: Refined linkage map of chromosome 5 in the region of spinal muscular atrophy gene. Genomics 15:521-524 ,1993
  196. J. Inazawa , H. Saito, T. Ariyama, T. Abe, and Y. Nakamura: High-resolution cytogenetic mapping of 342 new cosmid markers on human chromosome 17 by fluorescent in situ hybridization. Genomics 17:153-162 ,1993
  197. Y. Horio , Ta. Takahashi, T. Kuroishi, K. Hibi, M. Suyama, T. Niimi, K. Shimokata, K. Yamakawa, Y. Nakamura, R. Ueda, and To. Takahashi: Prognostic significance of p53 mutation and 3p deletion in primary resected non-small cell lung cancer. Cancer Research 53:1-4,1993
  198. A.J. Sandford , T. Shirakawa, M.F. Moffatt, S.E. Daniels, C. Ra, J.A. Faux, R.P. Young, Y. Nakamura, G.M. Lathrop, W. Cookson and J.M. Hopkin:Localization of atopy and the βsubunit of the high affinity IgE receptor (FcERI) on chromosome 11q. Lancet 341:332-334 ,1993
  199. M. Emi, Y. Fujiwara, H. Ohata, H. Tsuda, S. Hirohashi, M. Koike, M. Miyaki, M. Monden, and Y. Nakamura: Allelic loss of chromosome band 8p21.3-p22 is associated with progression of hepatocellular carcinoma. Genes Chromosomes and Cancer, 7:152-157, 1993
  200. P.A. Crossey , E.R. Maher, M.H. Jones, F.M. Richards, F. Latif, M.E. Pipps, M. Lush, K. Foster, K. Tory, J.S. Green, B. Oostra, J.R.W. Yates, W.M. Linehan, N.A. Affara, M. Lerman, B. Zbar, Y. Nakamura, and M.A. Ferguson-Smith: Genetic linkage between Von Hippel-Lindau disease and three microsatellite polymorphisms refines the localization of the VHL locus. Human Molecular Genetics 2:279-282 ,1993
  201. S. Takiguchi , T. Tokino, T. Imai, A. Tanigami, K. Koyama, and Y. Nakamura: Identification and characterization of a cDNA, which is highly homologous to the ribonucleoprotein gene, from a locus (D10S102) closely linked to MEN2 (multiple endocrine neoplasia type 2). Cytogenetics Cell Genetics 64:128-130 ,1993
  202. T. Mori , H. Nagase, T. Aoki, H. Arakawa, T. Nishihira, S. Mori, and Y. Nakamura: The APC (adenomatous polyposis coli) gene: a novel mutation in an FAP patient and a DdeI polymorphism in the 5' non-coding region. Human Mutation 2:240-243 ,1993
  203. S. Mole , M. Jackson, T. Tokino, Y. Nakamura, and B. Ponder: Assignment of fifty-four cosmid clones to five regions of chromosome 10. Genomics 15:457-458 ,1993
  204. S. Ichii, H. Nagase, T. Mori, S. Baba, and Y. Nakamura: A novel mutation of the APC (adenomatous polyposis coli) gene in a familial adenomatous polyposis (FAP) patient and presymptomatic diagnosis using PCR. Human Molecular Genetics 2:597,1993
  205. T. Miwa , K. Sudo, Y. Nakamura, and T. Imai: Fifty sequenced-tagged sites on human chromosome 11. Genomics 17:211-214 ,1993
  206. T. Sato , T. Sakamoto, K. Takita, H. Saito, K. Okui, and Y. Nakamura: The human prohibitin (PHB) gene family and its somatic mutation in human tumors. Genomics 17:762-764 ,1993
  207. S. Ichii, S. Takeda, A. Horii, S. Nakatsuru, Y. Miyoshi, M. Emi, Y. Fujiwara, K. Koyama, J. Furuyama, J. Utsunomiya, and Y. Nakamura: Detailed analysis of genetic alterations in colorectal tumors from patients with and without familial adenomatous polyposis (FAP). Oncogene 8:2399-2405 ,1993
  208. M. Koi , L.A. Johnson, L.M. Kalikin, P.F.R. Little, Y. Nakamura, and A. Feinberg: Tumor cell growth arrest caused by subchromosomal transferable DNA fragments from chromosome 11. Science 260:361-369 ,1993
  209. E. Takahashi , S. Hitomi, K. Koyama, and Y. Nakamura: A high-resolution cytogenetic map of human chromosome 5: localization of 206 new cosmid markers by direct R-banding fluorescence in situ hybridization. Genomics 17:234-236 ,1993
  210. H. Saito , J. Inazawa, S. Saito, F. Kasumi, S. Koi, S. Sagae, R. Kudo, J. Saito, K. Noda, and Y. Nakamura:Detailed Deletion Mapping of Chromosome 17q in Ovarian and Breast Cancers: 2-cM Region on 17q21.3 Often and Commonly Deleted in Tumors. Cancer Research 53:3382-3385 ,1993
  211. E. Takahashi , K. Koyama, S. Hitomi, and Y. Nakamura: A high-resolution cytogenetic map of human chromosome 12: localization of 195 new cosmid markers by direct R-banding fluorescence in situ hybridization. Human Genetics 92:405-409 ,1993
  212. H. Han , A. Yanagisawa, Y. Kato, J. Park, and Y. Nakamura: Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer. Cancer Research 53:5087-5089 ,1993
  213. H. Nagase , Y. Nakamura: Mutations of the APC (adenomatous polyposis coli) gene. Human Mutation 2:425-434 ,1993
  214. T. Tokino , N. Davidson, K. Helzlsour, B. Zehnhauer, Y. Nakamura, B. Vogelstein, and D. Sidransky: Absence of germline prohibitin mutations in early onset breast cancer. International Journal of Oncology 3:769-772 ,1993
  215. S. Nakatsuru , A. Yanagisawa, Y. Furukawa, S. Ichii, Y. Kato, Y. Nakamura, and A. Horii: Somatic mutations of the APC gene in precancerous lesion of the stomach. Human Molecular Genetics 2:1463-1465 ,1993
  216. M. Konishi , R. Kikuchi-Yanoshita, K. Tanaka, C. Sato, K. Tsuruta, Y. Maeda, M. Koike, S. Tanaka, Y. Nakamura, N. Hattori, and M. Miyaki: Genetic changes and histopathological grades in human hepatocellular carcinomas Jpn. J. Cancer Research 84:893-899 ,1993
  217. M. Emi, T. Katagiri, Y. Harada, H. Saito, J. Inazawa, I. Ito, F. Kasumi, and Y. Nakamura: A novel metalloprotease/disintegrin-like gene at 17q21.3 that is somatically rearranged in two primary breast cancers. Nature Genetics 5:151-157 ,1993
  218. W. Liu M. , Piechocki, V. Shridhar, G. Lyles, Z. Song, Y. Nakamura, H. Drabkin, J. Vance, and D.I. Smith: The isolation of a yeast artificial chromosome (YAC) contig extending for 2 megabases in the vicinity of the Von Hippel Lindau disease gene. Human Molecular Genetics 2:1177-1182 ,1993
  219. H.-J. Han, T. Fujiwara, S. Shin, and Y. Nakamura: Dinucleotide repeat polymorphisms in the 3' non-coding region of the human receptor-type tyrosine kinase gene (flt).Human Molecular Genetics 2:2204,1993
  220. T. Toda , M. Segawa, Y. Nomura, I. Nonaka, K. Masuda, T. Ishihara, M. Suzuki, I. Tomita, Y. Origuchi, K. Ohno, N. Misugi, Y. Sasaki, K. Takada, M. Kawai , K. Ohtani, T. Murkami, K. Saito, Y. Fukuyama, T. Shimizu, I. Kanazawa, and Y. Nakamura: Localization of a gene responsible for Fukuyama type congenital muscular dystrophy (FCMD) to chromosome 9q31-33 by linkage analysis. Nature Genetics 5:283-286 ,1993
  221. R.J. Sinke , A. Tanigami, Y. Nakamura, and A. Geurts van Kessel: Reverse mapping of the gene encoding the human fos-related antigen-1 (fra-1) within chromosome band 11q13.Genomics 18:165,1993
  222. T. Tohma , T. Tamura, T. Ohta, H. Soejima, T. Kubota, Y. Jinno, K. Tsukamoto, Y. Nakamura, K. Naritomi, and N. Niikakwa: Cosmid clones from microdissected human chromosomal region 15q11-q13. Jpn. J. Human Genetics 38:267-275 ,1993
  223. M.E. Phipps, E.R. Maher, N.A. Affara, F. Latif, M.A. Leversha, M.E. Fergusonsmith, Y. Nakamura, M. Lerman, B. Zbar, and M.A. Fergusonsmith: Physical mapping of chromosome 3p25-p26 by fluorescence in-situ hybridization (fish). Human Genetics, 92:18-22, 1993

    1994　　↑ページトップへ

  224. A. Kurimasa , Y. Nagata, M. Emi, Y. Nakamura, and M. Oshimura: A human gene that restores the DNA-repair defect in SCID mice is located on 8p11.1-q11.1. Human Genetics 93:21-26 ,1994
  225. K. Yoshiura , J. Inazawa, K. Koyama, Y. Nakamura, and N. Niikawa: Mapping of the 8q translocation breakpoint of t(8;13) observed in a patient with multiple exostoses. Genes Chromosomes and Cancer 9:57-61 ,1994
  226. Y. Nakamura, K. Okui, E. Takahashi, and K. Koyama: Isolation and mapping of 328 new cosmid markers on human chromosome 8: construction of a high resolution cytogenetic map of chromosome 8 with 416 markers. Cytogenetics Cell Genetics 65:115-118 ,1994
  227. Y. Furukawa , S. Nakatsuru, A. Nagafuchi, S. Tsukita, T. Muto, Y. Nakamura, and A. Horii: Structure, Expression and chromosomal assignment of the human a-catenin gene. Cytogenetics Cell Genetics 65:74-78 ,1994
  228. J. Inazawa , T. Ariyama, T. Tokino, A. Tanigami, Y. Nakamura, and T. Abe: High-resolution ordering of DNA markers by multi-color fluorescent in situ hybridization of prophase chromosomes. Cytogenetics Cell Genetics 65:130-135 ,1994
  229. M. Isomura, A. Tanigami, H. Saito, Y. Harada, T. Katagiri, J. Inazawa, D.H. Ledbetter, and Y. Nakamura: Detailed analysis of loss of heterozygosity on chromosome band 17p13 in breast carcinoma on the basis of a high-resolution physical map with 29 markers. Genes Chromosomes and Cancer 9:173-179 ,1994
  230. T. Mori , H. Nagase, A. Horii, Y. Miyoshi, S. Nakatsuru, T. Aoki, H. Arakawa, A. Yanagisawa, Y. Ushio, S. Takano, M. Ogawa, M. Nakamura, M. Shibuya, R. Nishikawa, M. Matsutani, Y. Hayashi, H. Takahashi, F. Ikuta, T. Nishihira, S. Mori, and Y. Nakamura: Germ-line and somatic mutations of the APC gene in patients with Turcot syndrome and analysis of APC mutations in brain tumors. Genes Chromosomes and Cancer 9:168-172 ,1994
  231. K. Tsukamoto , Y. Nakamura, and N. Niikawa: Isolation of two isoforms of the HuP2 gene transcripts and their tissue-specific alternative expression in human adult tissues.Human Genetics 93:270-274 ,1994
  232. R.J. Sinke , D. Olde Weghuis, R.F. Suijkerbuijk, A. Tanigami, Y. Nakamura, C. Larsson, G. Weber, B. de Jong, J.W. Oosterhuis, W.A. Molenaar, and A. Geurts van Kessel: Molecular characterization of a recurring complex chromosomal translocation in two human extragonadal germ cell tumors. Cancer Genetics Cytogenetics 73:11-16,1994
  233. Y. Fujiwara, H. Ohata, M. Emi, K. Okui, K. Koyama, E. Tsuchiya, M. Monden, T. Mori, A. Kurimasa, M. Oshimura, and Y. Nakamura: A 3-Mb physical map of the region at chromosome 8p21.3-p22, including a 600-kb region commonly deleted in human hepatocellular carcinoma, colorectal cancer, and non-small cell lung cancer. Genes Chromosomes and Cancer 10:7-14,1994
  234. M.H. Jones, S. Koi, I. Fujimoto, K. Hasumi, K. Kato, and Y. Nakamura: Allelotype of Uterine cancer by analysis of RFLP and microsatellite polymorphisms: Frequent loss of heterozygosity on chromosomes arms 3p, 9q, 10q, and 17p. Genes Chromosomes and Cancer 9:119-123 ,1994
  235. T. Aoki , S. Takeda, A. Yanagisawa, Y. Kato, Y. Ajioka, H. Watanabe, S. Kudo, and Y. Nakamura: APC and p53 mutations in de novo colorectal adenocarcinomas. Human Mutation 3:342-346 ,1994
  236. O. Takeda , C. Homma, N. Maseki, M. Sakura, N. Kanda, M. Schwab, Y. Nakamura, and Y. Kaneko: There may be two tumor suppressor genes on chromosome 1p closely associated with biologically distinct subtypes of neuroblastoma. Genes Chromosomes and Cancer 10:30-39 ,1994
  237. T. Aoki , T. Mori, D. XiQun, T. Nishihira, T. Matsubara, and Y. Nakamura: Allelotype study of esophageal carcinoma. Genes Chromosomes and Cancer 10:177-182 ,1994
  238. T. Toda , A. Iida, T. Miwa, Y. Nakamura, and T. Imai: Isolation and characterization of a novel gene encoding nuclear protein at a locus (D11S636) tightly linked to multiple endocrine neoplasia type 1 (MEN1). Human Molecular Genetics 3:465-470 ,1994
  239. H. Tsuda, D.F. Callen, T. Fukutomi, Y. Nakamura, and S. Hirohashi: Allele loss on chromosome 16q24.2-qter occurs frequently in breast cancers irrespectively of differences in phenotype and extent of spread. Cancer Research 54:513-517 ,1994
  240. H. Arakawa , N. Hayashi, H. Nagase, M. Ogawa, and Y. Nakamura: Alternative splicing of the NF2 gene and its mutation analysis of breast and colorectal cancers. Human Molecular Genetics 3:565-568 ,1994
  241. T. Mori , T. Aoki, T. Matsubara, F. Iida, D. XiQun, T. Nishihira, S. Mori, and Y. Nakamura: Frequent loss of heterozygosity in the region including BRCA1 on chromosome 17q in squamous cell carcinomas of the esophagus. Cancer Research 54:1638-1640 ,1994
  242. K. Koyama , K. Sudo, and Y. Nakamura: Mapping of the human nicotinic acetylcholine receptor (nAChR) beta-3 Gene within Chromosome 8p11.2. Genomics 21:460-461 ,1994
  243. E. Arai , T. Ikeuchi, and Y. Nakamura: Characterization of the translocation breakpoint on chromosome 22q12.2 in a patient with neurofibromatosis type 2 (NF2). Human Molecular Genetics 3:937-940 ,1994
  244. E. Takahashi , K. Koyama, A. Hitomi, H. Itoh, and Y. Nakamura: A high-resolution cytogenetic map of human chromosome 9: Localization of 203 new cosmid markers by direct R-banding fluorescence in situ hybridization. Genomics 19:373-375 ,1994
  245. H. Arakawa , H. Nagase, N. Hayashi, T. Fujiwara, M. Ogawa, S. Shin, and Y. Nakamura: Molecular cloning and expression of a novel human gene that is highly homologous to human FK506-binding protein 12kD (hFKBP-12), and characterization of two alternatively spliced transcripts. Biochem. Biophy. Research Comm. 200:836-843 ,1994
  246. N. Iwai , N. Ohmichi, K. Hanai, Y. Nakamura, and M. Kinoshita: Human SA gene locus as a candidate for essential hypertension. Hypertension 23:375-380 ,1994
  247. M. Mannens , J.M.N. Hoovers, E. Redeker, M. Verjaal, A.P. Feinberg, P. Little, M. Boavida, N. Coad, M. Steenman, J. Bliek, N. Niikawa, H. Tonoki, Y. Nakamura, E.G. de Boer, R.M. Slater, R. John, J.K. Cowell, C. Junien, I. Henry, R. Weksberg, S.M. Pueshel, N.J. Leschot, A. Westerveld: Parental imprinting of human chromosome region 11p15.3-pter involved in the Beckwith-Wiedemann syndrome and various human neoplasia. Eur. J. Human Genetics 2:3-23,1994
  248. N. Uhrhammer , P. Concannon, Y. Huo, Y. Nakamura, and R.A. Gatti: A pulsed-field gel electrophoresis map in the ataxia-telangiectasia region of chromosome 11q22.3. Genomics 20:278-280 ,1994
  249. M. Nishiyama , J. Inazawa, T. Ariyama, Y. Nakamura, S. Matsufuji, A. Furusawa, T. Tanaka, S. Hayashi, and J.R. Wands: The human insulin receptor substrate-1 gene (IRS1) is localized on 2q36. Genomics 20:139-141 ,1994
  250. N. Hayashi , H. Arakawa, H. Nagase, M. Ogawa, and Y. Nakamura: Genetic diagnosis identifies occult lymph node metastases undetectable by the histopathological method. Cancer Research 54:3853-3856 ,1994
  251. T. Tanaka, K. Nakahara, N. Kato, T. Imai, T. Yamazaki, R. Nagai, Y. Yazaki, and Y. Nakamura:Genetic Linkage Analyses of Romano-Ward Syndrome (RWS) in 13 Japanese Families. Human Genetics 94:380-384 ,1994
  252. K. Hibi , K. Yamakawa, R. Ueda, Y. Horio, Y. Murata, M. Tamari, K. Uchida, T. Takahashi, Y. Nakamura, and T. Takahashi: Aberrant upregulation of a novel integrin a4 subunit gene at 3p21.3 in small cell lung cancer. Oncogene 9:611-619 ,1994
  253. S. Hosoe , K. Ueno, Y. Shigedo, I. Tachibana, T. Osaki, T. Kumagai, Y. Tanio, I. Kawase, Y. Nakamura, and T. Kishimoto:A frequent deletion of chromosome 5q21 in advanced small cell and non-small cell carcinoma of the lung. Cancer Research 54:1787-1790 ,1994
  254. Y. Harada , T. Katagiri, I. Itoh, F. Akiyama, G. Sakamoto, F. Kasumi, Y. Nakamura, and M. Emi: Genetic Studies In 457 Breast Cancers; Comparisons Between Clinicopathological Parameters and Genetic Alterations. Cancer 74:2281-2286 ,1994
  255. Y. Murata, M. Tamari, T. Takahashi, Y. Horio, K. Hibi, S. Yokoyama, J. Inazawa, K. Yamakawa, A. Ogawa, T. Takahashi and Y. Nakamura: Characterization of an 800-kb region at 3p22-p21.3 that was homozygously deleted in a lung cancer cell line and construction of a cosmid contig. Human Molecular Genetics 3:1341-1344 ,1994
  256. T. Ichikawa , N. Nihei, H. Suzuki, M. Oshimura, M. Emi, Y. Nakamura, I. Hayata, J.T. Isaacs, and J. Shimazaki: Suppression of metastasis of rat prostatic cancer by introducing human chromosome 8. Cancer Research 54:2299-2302 ,1994
  257. A. Horii , H.-J. Han, M. Shimada, A. Yanagisawa, Y. Kato, H. Ohta, W. Yasui, E. Tahara, and Y. Nakamura: Frequent Replication Errors at Microsatellite Loci in Tumors of Patients with Multiple Primary Cancers. Cancer Research 54:3373-3375 ,1994
  258. T. Mori , K. Miura, T. Aoki, T. Nishihira, S. Mori, and Y. Nakamura: Frequent Somatic Mutation of The MTS (Multiple Tumor Suppressor) 1/CDK4I (Cyclin-dependent kinase-4 inhibitor) gene in Esophageal Squamous Cell Carcinoma. Cancer Research 54:3396-3397 ,1994
  259. S. Nakatsuru , K. Sudo, and Y. Nakamura: Molecular cloning of a novel human cDNA homologous to CDC10 in Saccharomyces cerevisiae. Biochem. Biophy. Research Comm. 202:82-87 ,1994
  260. S. Hosoe , Y. Shigedo, K. Ueno, I. Tachibana, T. Osaki, Y. Tanio, I. Kawase K. Yamakawa, Y. Nakamura, and T. Kishimoto: Detailed deletion mapping of the short arm of chromosome 3 in small cell and non-small cell carcinoma of the lung. Lung Cancer 10:297-305 ,1994
  261. T. Toda , S. Ikegawa, K. Okui, E. Kondo, K. Saito, Y. Fukuyama, I. Kanazawa, and Y. Nakamura: Refined mapping of a gene responsible for Fukuyama type congenital muscular dystrophy; evidence for a strong linkage disequilibrium. Am. J. Human Genetics 55:946-950 ,1994
  262. N. Hayashi , Y. Sugimoto, E. Tsuchiya, M. Ogawa, and Y. Nakamura: Somatic Mutations of the MTS (Multiple Tumor Suppressor) 1/ CDK4I (Cyclin-Dependent Kinase-4 Inhibitor) gene in Human Primary Non-Small Cell Lung Carcinomas. Biochem. Biophy. Research Comm. 202:1426-1430,1994
  263. T. Tanaka, K. Okui, and Y. Nakamura: Assignment of the human caltractin gene to Xq28 by fluorescence in situ hybridization. Genomics 24:609-610 ,1994
  264. C.A. Westbrook , M.M. Le Beau, W.L. Neuman, M. Keinanen, L.H. Yamaoka, M.C. Speer, R. EspinosaIII, Y. Nakamura, R. Williamson, M. Mullan, and K. Buetow: Physical and genetic map of 5q31: use of fluorescence in situ hybridization data to identify errors in the CEPH database. Cytogenetics Cell Genetics 67:86-93 ,1994
  265. K. Sudo, K. Chinen, and Y. Nakamura: 2,058 expressed sequence tags (ESTs) from a human fetal lung cDNA library. Genomics 24:276-279 ,1994
  266. T. Mori , A. Yanagisawa, Y. Kato, K. Miura, T. Nishihira, S. Mori, and Y. Nakamura: Accumulation of Genetic Alterations during Esophageal Carcinogenesis. Human Molecular Genetics 3:1969-1971 ,1994
  267. M.H. Jones, T. Sato, H. Saito, A. Tanigami, and Y. Nakamura: Microsatellite polymorphisms at candidate and confirmed tumour suppressor gene loci for linkage and loss of heterozygosity analysis. Human Molecular Genetics 3:1911-1912 ,1994
  268. T. Sakamoto , Y. Nakamura, and T. Sato:Isolation of microsatellite markers in rainbow fish. J. Fish Biol. 44:1093-1096 ,1994
  269. J.-G. Park , H.-J. Han, M.-S. Kang, and Y. Nakamura: Presymptomatic diagnosis of familial adenomatous polyposis coli. Diseases of Colon and Rectum 37:700-707 ,1994
  270. H. Ohata, Y. Fujiwara, K. Koyama, and Y. Nakamura: Mapping of the human autoantigen pericentriolar material 1 (PCM1) gene to chromosome 8p21.3-p22. Genomics, 94:404-405, 1994
  271. M.R. James, C.W. Richard, J. Schott, C. Yousry, K. Clark, J. Bell, J.D. Terwilliger, J. Hazan, C. Dubay, A. Vignal, M. Agrapart, T. Imai, Y. Nakamura, M. Polymeropoulos, J. Weissenbach, D.R. Cox, and G.M. Lathrop: A radiation hybrid map of 506 STS markers spanning human chromosome 11. Nature Genetics 8:70-76 ,1994
  272. S. Sato , Y. Nakamura, and E. Tsuchiya: The difference of allelotype between squamous cell carcinoma and adenocarcinoma of the lung. Cancer Research 54:5652-5655 ,1994
  273. A. Horii , H.-J. Han, S. Sasaki, M. Shimada and Y. Nakamura: Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes. Biochem. Biophy. Research Comm. 204:1257-1264 ,1994
  274. M.J. Higgins , N.J. Smilinich, S. Sait, A. Koenig, J. Pongratz, M. Gessler, C.W. Richard, M.R. James, J.P. Sanford, B.-W. Kim, J. Cattelane, N.J. Nowak, C. Jones, Y. Nakamura, D.S. Gerhard, and T.B. Shows: An ordered NotI fragment map of chromosome band 11p15.Genomics 23:211-222 ,1994
  275. S. Baba , H. Ando, Y. Nakamura: Identification of germ line mutation of APC gene in possible carriers of familial adenomatous polyposis (FAP). Anticancer Res. 14:2189-2192 ,1994

    1995　　↑ページトップへ

  276. E. Takahashi , K. Koyama, M. Hirai, H. Itoh, and Y. Nakamura: A high-resolution cytogenetic map of human chromosome 2: Localization of 434 cosmid markers by direct R-banding fluorescence in situ hybridization. Cytogenetics Cell Genetics 68:112-114 ,1995
  277. S. Nakatsuru , K. Sudo, and Y. Nakamura: Isolation and mapping of a novel human gene encoding a product homologous to yeast proteins involving in DNA replication. Cytogenetics Cell Genetics 68:226-230 ,1995
  278. Y. Fujiwara, H. Ohata, T. Kuroki, K. Koyama, E. Tsuchiya, M. Monden, and Y. Nakamura: Isolation of a candidate tumor suppressor gene on chromosome 8p21.3-p22 that is homologous to an extracellular domain of the PDGF receptor beta gene. Oncogene 10:891-895 ,1995
  279. T. Katagiri, Y. Harada, M. Emi and Y. Nakamura: Human metalloprotease/disintegrin-like (MDC) Gene: Exon-intron organization and alternative splicing. Cytogenetics Cell Genetics 68:39-44 ,1995
  280. H. Arakawa , H. Nagase, N. Hayashi, M. Ogawa, M. Nagata, T. Fujiwara, E. Takahashi, S. Shin and Y. Nakamura: Molecular cloning, characterization, and chromosomal mapping of a novel human gene that is highly homologous to Xenopus transcription factor IIIA. Cytogenetics Cell Genetics 70:235-238 ,1995
  281. T. Ariyama , J. Inazawa, T. Ezaki, Y. Nakamura, A. Horii, and T. Abe: High-resolution cytogenetic mapping of the short arm of chromosome 1 with newly isolated 411 cosmid markers by fluorescence in situ hybridization: The precise order of 18 markers on 1p36.1 on prophase chromosomes and "stretched" DNAs. Genomics 25:114-123 ,1995
  282. Y. Hasegawa , S. Takeda, S. Ichii, K. Koizumi, M. Maruyama, A. Fujii, H. Ohta, T. Nakajima, M. Okuda, S. Baba, and Y. Nakamura: Detection of K-ras mutations in DNAs isolated from feces of patients with colorectal tumors by mutant-allele-specific amplification (MASA) Oncogene 10:1441-1445 ,1995
  283. I. Ito , M. Yoshimoto, T. Iwase, S. Watanabe, T. Katagiri, Y. Harada, F. Kasumi, S. Yasuda, T. Mitomi, M. Emi, and Y. Nakamura: Association of genetic alterations on chromosome 17 with loss of hormone receptors in breast cancer. British Journal of Cancer 71:438-441 ,1995
  284. K. Chinen, K. Sudo, E. Takahashi, and Y. Nakamura: Isolation and mapping of human beta-signal sequence receptor gene. Cytogenetics Cell Genetics 70:215-217 ,1995
  285. T. Kawakami , Y. Furukawa, K. Sudo, H. Sait, E. Takahashi, and Y. Nakamura: Isolation and mapping of a human gene that is highly homologous to PR-8, a rat gene associated with programmed cell death. Cytogenetics Cell Genetics 71:41-43 ,1995
  286. H.-J. Han, M. Maruyama, S. Baba, J.-G. Park, and Y. Nakamura: Genomic structure of human mismatch repair gene, hMLH1, and its mutation analysis in patients with hereditary non-polyposis colorectal cancer (HNPCC). Human Molecular Genetics 4:237-242 ,1995
  287. T. Ariyama , T. Kimura, K. Yamakawa, Y. Nakamura, T. Abe, and J. Inazawa: Precise ordering of 26 cosmid markers on chromosome region 3p23-p21.3 by two-color FISH on human prophase chromosomes and stretched DNAs. Cytogenetics Cell Genetics 70:129-133 ,1995
  288. T. Ariyama , J. Inazawa, Y. Uemura, N. Kakazu, T. Maekawa, F. Urase, K. Irimajiri, A. Horiuchi., Y. Nakamura, and T. Abe: Clonal origin of Philaderphia chromosome (ph)-negative cells with trisomy 8 appearing during the course of a-interferon therapy for Ph-positive chronic myolocytic leukemia. Cancer Genetics Cytogenetics 81:20-23 ,1995
  289. M. Kai , H. Arakawa, Y. Sugimoto, Y. Murata, M. Ogawa, and Y. Nakamura: Infrequent Mutation of The MTS1 Gene in Primary Bladder Carcinomas, Jpn. J. Cancer Research 86:249-251 ,1995
  290. K. Koyama , K. Sudo, and Y. Nakamura: Isolation of 115 human chromosome 8-specific expressed-sequence tags by exon amplification. Genomics 26:245-253 ,1995
  291. S. Ikegawa , K. Sudo, K. Okui, and Y. Nakamura: Isolation, characterization and chromosomal assignment of human colligin-2. Cytogenetics Cell Genetics 71:182-186,1995
  292. S. Ikegawa , Y. Fukushima, M. Isomura, and Y. Nakamura: Mutations of the fibroblast growth factor receptor-3 gene in one familial and six sporadic cases of Japanese patients with achondroplasia. Human Genetics 96:309-311 ,1995
  293. N.K. Spurr, S. Blanton, R. Bookstein, R. Clarke, R. Cottingham, S.Daiger, D. Drayna, P. Faber, S. Horrigan, K. Kas, C. Kirchgessner, S. Kumar, R.J. Leach, J-J. Luedecke, Y. Nakamura, M-J. Pebusque, S. Ranta, E. Sim, L.S. Sullivan, L. Takle, J. Vance, M. Wagner, D. Wells, C. Westbrook, L. Yaremko, D. Zaletayev, O. Zuffardi, and S. Wood: Report of the second international workshop on human chromosome 8 mapping 1994. Cytogenetics Cell Genetics, 68:147-164, 1995
  294. A. Iida, K. Blake, T. Tunny, S. Klemm, M. Stowasser, N. Hayward, R. Gordon, Y. Nakamura, and T. Imai: Allelic losses on chromosome band 11q13 in aldosterone-producing adrenal tumors. Genes Chromosomes and Cancer 12:73-75 ,1995
  295. T. Kuroki , Y. Fujiwara, E. Tsuchiya, S. Nakamori, Y. Imaoka, T. Kanematsu, and Y. Nakamura: Accumulation of genetic changes during development and progression of hepatocellular carcinoma: LOH on chromosome 1p occurs at an early stage of hepatocarcinognesis. Genes Chromosomes and Cancer 13:163-167 ,1995
  296. N. Hayashi , I. Ito, A. Yanagisawa, Y. Kato, S. Nakamori, S. Imaoka, H. Watanabe, M. Ogawa, and Y. Nakamura: Genetic diagnosis of lymph-node metastasis allows accurate prognosis of patients with colorectal cancer. Lancet 345:1257-1259 ,1995
  297. N. Hashimoto , D. Ichikawa, Y. Arakawa, K. Date, S. Ueda, Y. Nakagawa, A. Horii, Y. Nakamura, T. Abe, and J. Inazawa:Frequent deletions of chromosome 1p in oligodendroglial tumors revealed by double color fluorescence in situ hybridization and microsatellite analysis. Genes Chromosomes and Cancer 14:295-300 ,1995
  298. K. Miura , K. Okita, Y. Furukawa, S. Matsuno, and Y. Nakamura: Deletion Mapping in Squamous Cell Carcinomas of the Esophagus Defines a Region Containing a Tumor Suppressor Gene Within a 4-cM Interval of the Distal Long Arm of Chromosome 9. Cancer Research 55:1828-1830 ,1995
  299. T. Toda , M. Yoshioka, Y. Nakahori, I. Kanazawa, Y. Nakamura, and Y. Nakagome: Genetic identity of Fukuyama-type congenital muscular dystrophy and Walker-Warburg syndrome. Ann. Neurol 37:99-101 ,1995
  300. H. Soejima , K. Yoshiura, T. Tamura, T. Tokino, Y. Nakamura, Y. Niikawa, and Y. Jinno: Fifty novel sequences-tagged sites (STSs) on human chromosome 11q13.4-q25 identified from microclones generated by microdissection. Cytogenetics Cell Genetics 70:108-111 ,1995
  301. S. Inoue , A. Orimo, Y. Matsuda, J. Inazawa, M. Emi, Y. Nakamura, T. Hori, and M. Muramatsu: Chromosomal mapping of human (ZNF147) and mouse gene for estrogen-responsive finger protein (efp), a member of the RING finger family. Genomics 25:581-583 ,1995
  302. T. Kuroki , Y. Fujiwara, S. Nakamori, Y. Imaoka, T. Kanematsu, and Y. Nakamura: Evidence for the Presence of Two Tumor Suppressor Genes for Hepatocellular Carcinoma on Chromosome 13q. British Journal of Cancer 72:383-385 ,1995
  303. M. Shimada , A. Horii, S. Sasaki, A. Yanagisawa, Y. Kato, K. Yamashita, K. Okagawa, K. Yamasaki, S. Ishiguro, M. Inoue, H. Shiozaki, and Y. Nakamura: Infrequent Replication Errors at Microsatellite Loci in Tumors of Patients with Multiple Primary Cancers of the Esophagus and Various Other Tissues. Jpn. J. Cancer Research 86:511-515 ,1995
  304. K. Sudo, E. Takahashi, and Y. Nakamura: Isolation and mapping of human cDNA homologous to murine protein synthesis initiation factor 4A-II (eIF4A-II), Cytogenetics Cell Genetics 71:385-388 ,1995
  305. K. Kobayashi , S. Sagae, R. Kudo, H. Saito, S. Koi, and Y. Nakamura: Microsatellite Instability in Endometrial Carcinomas; Frequent Replication Errors in Tumors of Early Onset and or of Poorly Differentiated Type, Genes Chromosomes and Cancer 14:128-132 ,1995
  306. M. Matsushima, K. Kobayashi, M. Emi, H. Saito, J. Saito, K. Suzumori, Y. Nakamura: Mutations of the BRCA1 gene in ovarian cancers. Human Molecular Genetics 4:1953-1956 ,1995
  307. H. Suzuki , M. Emi, A. Komiya, Y. Fujiwara, R. Yatani, Y. Nakamura, and J. Shimazaki: Localization of a tumor suppressor gene associated with progression of human prostate cancer within a 1.2 Mb region of 8p22-21.3. Genes Chromosomes and Cancer 13:168-174 ,1995
  308. T. Watanabe, T.Fujiwara, H. Shinomiya, Y. Kuga, H. Hishigaki, Y. Nakamura, and Y.Hirai: Molecular cloning of a novel human cDNA, RT14, containing a putative ORF highly conserved between human, fruit fly, and nematode. DNA Research 2:235-237 ,1995
  309. T. Toda , S. Ikegawa, M. Miyake, Y. Nakahori, and Y. Nakamura: Dinucleotide repeat polymorphism on chromosome 9q32. Jpn. J. Human Genetics 40:333-334 ,1995
  310. Y. Nakamura, The APC (Adenomatous Polyposis Coli) gene and human cancers. JCRCO 121:529-534 ,1995
  311. T. Fujiwara , A. Kawai, F. Shimizu, H. Hirano, S. Okuno, S. Takeda, K. Ozaki, Y. Shimada, M. Nagata, T. Watanabe, A. Takaichi, E. Takahashi, Y. Nakamura, and S. Shin: Cloning, sequencing and expression of a novel cDNA encoding human vacuolar ATPase (14-kDa subunit). DNA Research 2:107-111 ,1995
  312. S. Takiguchi-Shirahama , K. Koyama, A. Miyauchi, T. Wakasugi, S. Oishi, H. Takami, K. Hikiji, and Y. Nakamura: Germline mutations of the RET proto-oncogene in eight Japanese patients with multiple endocrine neoplasia (MEN2A). Human Genetics 95:187-190 ,1995
  313. R.M.W. Hofstra , T. Stelwagen, B. Pasini, A.Y. van der Veen, B. Ponder, Y. Nakamura, G. Romeo. C.H.C.M. Buys:Ordering of markers in the pericentromeric region of chromosome 10. Human Genetics 96:116-118 ,1995
  314. J. Nahmias , N. Horinigold, J. Fitzgibbon, K. Woodward, A. Pilz, D. Griffin, E.P. Henske, Y. Nakamura, S. Graw, F. Florian, F. Benham, S. Povey, and J. Wolfe: Cosmid contigs spanning 9q34 including the candidate region for TSC1. Eur. J. Human Genetics 3:65-77 ,1995
  315. M. Litt , P. Kramer, E. Korte, P. Fain, S. Cox, D. Root, R. White, J. Weissenbach, H. Doniskeller, R.Gatti, J. Weber, Y. Nakamura, C. Julier, K. hayashi, N. Supurr, M. Dean, J. Mandel, K. kidd, T. Kruse, A. Retief, A. bale, T. Meo, G. Vergnaud, S. Warren, and H.F. Willard; The CEPH consortium linkage map of human chromosome 11Genomics 27:101-112 ,1995

    1996　　↑ページトップへ

  316. N. Hayashi , S. Sugai, I. Ito, S. Nakamori, M. Ogawa, and Y. Nakamura: Ethnic difference in the pattern of K-ras oncogene mutations in human colorectal cancers. Human Mutation 8:258-261 ,1996
  317. M. Inoue , M. Isomura, S. Ikekawa, T. Fujiwara, S. Shin, H. Moriya, Y. Nakamura: Isolation and characterization of a novel human cDNA clone homologous to a yeast transcription activator, GCN5. Cytogenetics Cell Genetics 73:134-136 ,1996
  318. Y. Furukawa , T. Kawakami, K. Sudo, J. Inazawa, A. Matsumine, T. Akiyama, Y. Nakamura: Isolation and mapping of a novel human gene that is homologous to RPD3, a transcription factor in Saccharomyces cerevisiae. Cytogenetics Cell Genetics 73:130-133 ,1996
  319. S. Sasaki , A. Horii, M. Shimada, H.-J. Han, A. Yanagisawa, T. Muto, and Y. Nakamura: Somatic Mutations of a Human Mismatch Repair Gene, hMLH1, in Tumors from Patients with Multiple Primary Cancers. Human Mutation 7:275-278 ,1996
  320. T. Katagiri, M. Emi, I. Ito, K. Kobayashi, M. Yoshimoto, S. Watanabe, T. Iwase, F. Kasumi, Y. Miki, M.H. Skolnick, and Y. Nakamura: Mutations in the BRCA1 gene in Japanese Breast Cancer Patients. Human Mutation 7:334-339 ,1996
  321. H. Saito , T. Fujiwara, S. Shin, K. Okui, and Y. Nakamura: Cloning and mapping of a human novel cDNA that encodes a protein highly homologous to yeast nuclear protein NHP2. Cytogenetics Cell Genetics 72:191-193 ,1996
  322. T. Ezaki , M. Watanabe, T. Hibi, S. Aiso, K. Ohta, T. Nakajima, A. Yanagisawa, Y. Kato, T. Ariyama, J. Inazawa, Y. Nakamura and A. Horii: Deletion Mapping on Chromosome 1p in Well-differentiated Type of Gastric Cancer. British Journal of Cancer 73:424-428 ,1996
  323. H. Saito , T. Fujiwara, E. Takahashi, S. Shin, and Y. Nakamura: Isolation and Mapping of a Novel Human Gene Encoding a Protein Containing Zinc-Finger Structures, Genomics 31:376-379 ,1996
  324. K. Koyama , Y. Fukushima, J. Inazawa, N. Takahashi, and Y. Nakamura: The human homologue of the murine mgl-I gene maps within the Smith-Magenis-Syndrome region in 17p11.2. Cytogenetics Cell Genetics 72:78-85 ,1996
  325. M. Isomura, K. Okui, T. Fujiwara, S. Shin, and Y. Nakamura: Cloning and mapping of a novel human cDNA homologous to DROER, the enhancer of the Drosophila melanogaster rudimentary gene. Genomics 32:125-127 ,1996
  326. H.-J. Han, K. Sudo, J. Inazawa, and Y. Nakamura: Isolation and mapping of a human novel gene encoding small-GTP binding protein homologous to Ras-related RAB gene. Cytogenetics Cell Genetics 73:137-144 ,1996
  327. K. Kobayashi , M. Matsushima, S Koi, H. Saito, S. Sagae, R. Kudo and Y. Nakamura: Mutational analysis of mismatch repair genes hMLH1 and hMSH2 in sporadic endometrial carcinomas with microsatellite instability. Jpn. J. Cancer Research 87:141-145 ,1996
  328. T. Tanaka, J. Inazawa, and Y. Nakamura: Molecular cloning and mapping of a human cDNA for cytosolic malate dehydrogenase. Genomics 32:128-130 ,1996
  329. S. Ninomiya , M. Isomura, K, Narahara, Y. Seino, and Y. Nakamura: Isolation of a testis-specific cDNA on chromosome 17q from a region adjacent to the breakpoint of t(12;17) observed in a patient with acampomelic campomelic dysplasia and sex reversal. Human Molecular Genetics 5:69-72 ,1996
  330. T. Watanabe, T.Fujiwara, A. Kawai, F. Shimizu, S. Takami, H. Hirano, S. Okuno, K. Ozaki, S. Takeda, M. Nagata, A. Takaichi, E.Takahashi, Y. Nakamura, and S. Shin: Cloning, expression, and mapping of UBE2I, a gene encoding a human homologue of ubiquitin-conjugating enzymes that are critical for regulating the cell cycle in yeast. Cytogenetics Cell Genetics 72:86-89 ,1996
  331. T. Katagiri, K. Ozaki, T. Fujiwara, F. Shimizu, A. Kawai, S. Okuno, M. Suzuki, Y. Nakamura, E. Takahashi, and Y. Hirai: Cloning, expression and chromosome mapping of adducin-like 70 (ADDL), a human cDNA highly homologous to human erythrocyte adductin. Cytogenetics Cell Genetics 74:90-95 ,1996
  332. T. Tokino , T. Urano, T. Furuhata, M. Matsushima, T. Miyatsu, S. Sasaki, and Y. Nakamura: Characterization of the human p57KIP2 gene; Alternative splicing, Insertion/deletion polymorphisms in VNTR sequences in the coding region, and mutational analysis. Human Genetics 97:625-631 ,1996
  333. M. Shimada , A. Yanagisawa, Y. Kato, M. Inoue, H. Shiozaki, M. Monden and Y. Nakamura: Frequent Deletion of 3p and 17p in Premalignant Lesions During Esophageal Carcinogenesis. Genes Chromosomes and Cancer 15:165-169 ,1996
  334. T. Tanaka, J. Inazawa, Y. Nakamura: Molecular cloning of a novel human cDNA encoding putative cysteine protease and its chromosomal assignment to 14q32.1. Cytogenetics Cell Genetics 74:120-123 ,1996
  335. T. Mori , K. Miura, T. Fujiwara, S. Shin, J. Inazawa, and Y. Nakamura: Isolation and mapping of a novel human gene homologous to yeast CDCs 3, 10, 11, and 12, and mouse DIFF6. Cytogenetics Cell Genetics 73:224-227 ,1996
  336. K. Okita , T. Tokino, H. Nishimori, K. Miura, H. Nikaido, J. Hayakawa, A. Ono, M. Kuwajima, Y. Matsuzawa and Y. Nakamura: Definition of the locus responsible for systemic carnitine deficiency within a 1.6-cM region of mouse chromosome 11 by detailed linkage analysis. Genomics 33:289-291 ,1996
  337. K. Chinen, E. Takahashi, and Y. Nakamura: Isolation and mapping of a novel gene, partially homologous to yeast SEC14, that contains variable number of tandem repeat (VNTR) in the 3' untranslated region, Cytogenetics Cell Genetics 73:218-223 ,1996
  338. T. Ohta , M. Nakano, T. Tsujita, K. Abe, K. Osoegawa, T. Yamagata, K. Yoshiura, Y. Jinno, E. Soeda, Y. Nakamura, and N. Niikawa: Isolation of a cosmid clone corresponding to an inv(21) breakpoint of a patient with transient abnormal myelopoiesis. Am. J. Human Genetics 58:544-550 ,1996
  339. S. Sasaki , T. Tokino, T. Miyatsu, T.Muto and Y. Nakamura: Mutational analysis of the hMLH1 gene using an automated two-dimensional DNA typing system. Human Mutation 7:275-278 ,1996
  340. K. Miura , K. Suzuki, T.Tokino, M. Isomura, J.Inazawa, S. Matsuno and Y. Nakamura: Detailed deletion mapping in squamous cell carcinomas of the esophagus narrows a region containing a putative tumor suppressor gene to about 200 kb on distal chromosome 9q. Cancer Research 56:1629-1634 ,1996
  341. T. Tanaka, A. Ogiwara, I. Uchiyama, T. Takagi, and Y. Nakamura: Construction of a normalized directionally-cloned cDNA library from adult heart and analysis of 3040 clones by partial sequencing. Genomics 35:231-235 ,1996
  342. T. Watanabe, F. Shimizu, M. Nagata, A. Kawai, T. Fujiwara, Y. Nakamura, E. Takahashi, Y.Hirai: Cloning, expression, and mapping of CKAP1, which encodes a putative cytoskeleton-associated protein containing a CAP-GLY domain. Cytogenet. Cytogenetics Cell Genetics 72:208-211 ,1996
  343. K. Ozaki, T. Kuroki, S. Hayashi, and Y. Nakamura: Isolation of three testis-specific genes by a differential mRNA display method. Genomics 36:316-319 ,1996
  344. S. Ikegawa , T. Toda, K. Okui and Y. Nakamura: Structure and chromosomal assignment of the human S1-5 Gene that Is highly homologous to fibrillin. Genomics 35:590-592 ,1996
  345. M. Isomura, K. Okui, T. Fujiwara, S. Shin, and Y. Nakamura: Isolation and mapping of a novel human cDNA that encodes a protein homologous to RalGDS. Cytogenetics Cell Genetics 74:263-265 ,1996
  346. K. Ozaki, T. Fujiwara, A. Kawai, F. Shimizu, S. Takami, S. Okuno, S. Takeda, Y. Shimada, M. Nagata, T. Watanabe, A. Takaichi, E. Takahashi, Y. Nakamura, and S. Shin: Cloning, expression and chromosomal mapping of a novel cyclophilin-related gene (PPIL1) from human fetal brain. Cytogenetics Cell Genetics 72:242-245 ,1996
  347. S. Matuda , J.K. Tuzuki, M. Ohsugi, M. Yoshida, M. Emi, Y. Nakamura, Y. Yoshida, A.F. Nishiyama and T. Yamamoto: Tob, a novel protein that interacts with p185erbB2, is associated with anti-proliferative activity. Oncogene 12:705-713 ,1996
  348. L.A. James , D.J. Ogilvie, K. Yamakawa, Y. Nakamura, C.J. Stirling, and R. Anand: Walking, cloning, and mapping with YACs in 3q27: Localization of five ESTs including three members of the cystatin gene family and identification of CpG island. Genomics 32:425-430 ,1996
  349. D. Ichikawa, N. Hashimoto, M. Hoshima, T. Yamaguchi, K. Sawai, Y. Nakamura, T. Takahashi, T. Abe, J. Inazawa: Analysis of numerical aberrations in specific chromosomes by fluorescent in situ hybridization as a diagnostic tool in breast cancer. Cancer, 77:2064-2069, 1996
  350. A. Matsumine, T. Senda, G-H. Baeg, B.C. Roy, Y. Nakamura, M. Noda, K. Toyoshima, and T. Akiyama: MCC, a cytoplasmic protein that blocks cell cycle progression from the G0/G1 to S phase. Journal of Biological Chemistry 271:10341-10346 ,1996
  351. Y. Nakamura, Application of DNA markers to clinical genetics. Jpn. J. Human Genetics 41:1-10,1996
  352. T. Watanabe, T.Fujiwara, F.Shimizu, S.Okuno, M.Suzuki, E.Takahashi, Y. Nakamura, Y.Hirai: Cloning, expression, and mapping of a putative human homologue of murine tctex-1 gene, to 6q. Cytogenetics Cell Genetics 73:153-156 ,1996
  353. S. Ikegawa , Y. Kumano,K. Okui, T. Fujiwara, E. Takahashi and Y. Nakamura: Isolation, characterization and chromosomal assignment of the human WNT7a gene. Cytogenetics Cell Genetics 74:149-156 ,1996
  354. Y. Miki, T. Katagiri, F. Kasumi, T. Yoshimoto and Y. Nakamura: Mutation analysis in the BRCA2 gene in primary breast cancers. Nature Genetics 13:245-247 ,1996
  355. H.-J. Han, Y. Yuan, J.-L. Ku, J.-H. Oh, Y.-J. Won, K.J. Kang, K.Y. Kim, S. Kim, C.Y. Kim, J.-P. Kim, N.G. Oh, K.H. Lee, K.J. Choe, Y. Nakamura, and J.-G. Park: Germline mutations of hMLH1 and hMSH2 genes in Korean Hereditary Nonpolyposis Colorectal Cancer. J. Natl. Cancer Inst., 88:1317-1319, 1996
  356. I. Ishikawa , M. Ozaki, Y. Tominaga, and Y. Nakamura: Cytogenetic abnormalities in renal cell carcinomas associated with uremic aquired renal cystic disease. J. Kanazawa Med. Univ. 21:76-81 ,1996
  357. K. Wakui, H. Ohashi, A. Yamagishi, S. Hamano, T. Nara, S. Ishikiriyama, Y. Nakamura, and Y. Fukushima: Interstitial Duplication 8q22-q24: Report of a case proven by FISH with mapped cosmid probes. American journal of Medical Genetics, 65:36-39, 1996
  358. M. Matsushima, J. Inazawa, E. Takahashi, K. Suzumori, and Y. Nakamura: Molecular cloning and mapping of a human cDNA encoding a protein homologous to fungal Sterol-C5-desaturase. Cytogenetics Cell Genetics 74:252-254 ,1996
  359. T. Katagiri, Y. Nakamura, and Y. Miki: Mutations in the BRCA2 gene in hepatocellular carcinomas. Cancer Research 56:4575-4578 ,1996
  360. T. Watanabe, F. Shimizu, M. Nagata, A. Takaichi, T. Fujiwara, Y. Nakamura, E. Takahashi, and Y.Hirai: Cloning, expression pattern and mapping to 12p13.2-p13.1 of CLAPS3, a gene encoding a novel clathrin-adaptor small chain. Cytogenetics Cell Genetics 73:214-217 ,1996
  361. T. Furuhata , T. Urano, T. Tokino, and Y. Nakamura: Isolation of a novel GPI-anchored gene specifically regulated by p53, and correlation between its expression and anti-cancer drug sensitivity. Oncogene 13:1965-1970 ,1996
  362. T. Toda , M. Miyake, K. Kobayashi, K. Mizuno, K. Saito, M. Osawa, Y. Nakamura, I. Kanazawa, Y. Nakagome, K. Tokunaga, and Y. Nakahori: Linkage disequilibrium mapping narrows the Fukuyama-type congenital muscular dystrophy (FCMD) candidate region to less than 100 kb. Am. J. Human Genetics 59:1313-1320 ,1996
  363. F. Shimizu , T.K. Watanabe, T. Fujiwara, E. Takahashi, Y. Nakamura, and H. Maekawa: Isolation and mapping of human glycoprotein M6 gene (GMP6A) to 4q33-q34. Cytogenetics Cell Genetics 74:138-139,1996
  364. T. Watanabe, A. Kawai, T. Fujiwara, H. Maekawa, Y.Hirai, Y. Nakamura, and E. Takahashi: Molecular cloning of UBE2G, encoding a human skeletal muscle-specific ubiquitin-conjugating enzyme homologous to UBC7 of C. elegans. Cytogenetics Cell Genetics 74:146-148 ,1996
  365. T. Watanabe, T. Fujiwara, Y. Nakamura, Y. Hirai, H. Maekawa, and E. Takahashi: Cloning, expression pattern and mapping to Xq of NAP1L3, a gene encoding a peptide homologous to human and yeast nucleosome assembly proteins. Cytogenetics Cell Genetics, 74:281-285, 1996
  366. S. Saito, S. Sirahama, M. Matsushima, M. Suzuki, S. Sagae, R. Kudo, J. Saito, K. Noda, and Y. Nakamura: Definition of a commonly-deleted region in ovarian cancers to a 300-kb segment of chromosome 6q27. Cancer Research 15:5586-5589 ,1996
  367. T. Watanabe, T. Katagiri, M. Suzuki, F. Shimizu, T. Fujiwara, N. Kanemoto, Y. Nakamura, Y. Hirai, H. Maekawa, and E. Takahashi: Cloning and characterization of two novel human cDNAs (NELL1 and NELL2) encoding proteins with six EGF-like repeats. Genomics 38:273-276 ,1996
  368. K. Chinen, M. Isomura, K. Izawa, Y. Fujiwara, H. Ohata, T. Iwamasa, and Y. Nakamura: Construction of a cosmid contig map and isolation of exon-like fragments from 8p21.3-p22, a region that is commonly deleted in hepatocellular, colorectal, and non-small cell lung carcinomas. Cytogenetics Cell Genetics 72:190-196 ,1996
  369. K. Tsukamoto , N. Ito, M. Yoshimoto, T. Iwase, T. Tada, F. Kasumi, Y. Nakamura, and M. Emi: Two distinct commonly deleted regions on chromosome 13q suggest involvement of BRCA2 and RB genes in sporadic breast cancers. Cancer 78:1929-1934 ,1996

    1997　　↑ページトップへ

  370. A. Iida, R. Isobe, M. Yoshimoto, T. Iwase, T. Tada, F. Kasumi, Y. Nakamura, and M. Emi: Localization of a breast cancer tumor suppressor gene to a 3-cM interval within chromosomal region 16q22. British Journal of Cancer 75:264-267 ,1997
  371. H. Saito , S. Nakatsuru, J. Inazawa, and Y. Nakamura: Frequent association of alternative splicing of NER, a nuclear hormone receptor gene, in cancer tissues. Oncogene 14:617-621 ,1997
  372. S. Ishikawa , M. Kai, Y. Takei, K. Kuwata, K. Okui, M. Suzuki, M. Ogawa, and Y. Nakamura: Isolation and mapping of a novel human zinc finger gene homologous to SRE-ZBP, a serum-response-element binding protein. Cytogenetics Cell Genetics 77:185-189 ,1997
  373. S. Ikegawa , K. Nakamura, A. Nagano, N. Haga, and Y. Nakamura: Mutations in the N-terminal globular domain of the type X collagen gene (COL10A1) In patients with Schmid metaphyseal chondrodysplasia. Human Mutation 9:131-135 ,1997
  374. S. Matsumoto , F. Kasumi, G. Sakamoto, M. Onda, Y. Nakamura, and M. Emi: detailed deletion mapping of chromosome arm 3p in breast cancers: A 2-cM region on 3p14.3-21.1 and a 5-cM region on 3p24.3-25.1 commonly deleted in tumors. Genes Chromosomes and Cancer 20:268-274 ,1997
  375. T. Tanaka, R. Nagai, H. Tomoike, S. Takada, K. Yano, K. Yabuta, N. Haneda, O. Nakano, A.Shibata, T.Sawayama, H. Kasai, Y. Yazaki, and Y. Nakamura: Mutational analysis of familial long QT syndrome: Implication of correlation between mutant gene and response to beta-adrenergic blocking agents. Circulation 95:565-567 ,1997
  376. K. Suzuki , Y. Daigo, S. Fukuda, T. Tokino, M. Isomura, K. Isono, B. Wainwright, and Y. Nakamura: No evidence of mutation in the human PTC gene, responsible for NBCC syndrome, in human primary squamous cell carcinomas of the esophagus and lung. Jpn. J. Cancer Research 88:225-228 ,1997
  377. S. Hayashi , T. Kuroki, K. Ozaki, H. Kohsaki, T. Yamori, T. Tsuruo, S. Nakamori, S. Imaoka, M. Endo, and Y. Nakamura: Isolation of murine and human homologues of the fission-yeast dis3+ gene encoding a mitotic-control protein and its overexpression in cancer cells with progressive phenotypes. Cancer Research 57:921-925 ,1997
  378. Y. Kimura , T. Furuhata, T. Urano, K. Hirata, Y. Nakamura, and T. Tokino: Genomic structure and chromosomal localization of GML (GPI-anchored molecule-like protein), a gene induced by p53. Genomics 41:477-480 ,1997
  379. S. Ishikawa , M. Kai, M. Tamari, Y. Takei, K Takeuchi, H. Bandou, Y. Yamane, M. Ogawa, and Y. Nakamura: Sequence analysis of a 685-kb genomic region on chromosome 3p22-p21.3 that is homozygously deleted in a lung carcinoma cell line. DNA Research 4:35-43 ,1997
  380. Y. Kimura , T. Furuhata, T. Shiratsuchi, H. Nishimori, K. Hirata, Y. Nakamura, and T. Tokino: GML sensitizes cancer cells to Taxol by induction of apoptosis, Oncogene 15:1369-1374 ,1997
  381. S. Ishikawa , T. Takahashi, M. Ogawa, and Y. Nakamura: Genomic structure of the human PLCd1 (phospholipase C delta 1) locus on 3p22-21.3. Cytogenetics Cell Genetics 78:58-60 ,1997
  382. S. Tamura , S. Nakamori, T. Kuroki, Y. Sasaki, S. Imaoka, H. Furukawa, O. Ishikawa, and Y. Nakamura: Association of cumulative allelic losses with tumor agressiveness in hepatocellular carcinoma. J. Hepatology 27:669-677 ,1997
  383. Y. Daigo, K. Suzuki, O. Maruyama, Y. Miyoshi, T. Yasuda, T. Kabuto, S. Imaoka, T. Fujiwara, E Takahashi, M. Fujino, and Y. Nakamura: Isolation, mapping, and mutation analysis of a human cDNA homologous to the doc-1 gene of Chinese hamster, a candidate tumor suppressor for oral cancer. Genes Chromosomes and Cancer 20:204-207 ,1997
  384. T. Kimura , Y. Arakawa, S. Inoue, Y. Fukushima, I. Kondo, K. Koyama, T. Hosoi, A. Orimo, M. Muramatsu, Y. Nakamura, T. Abe, and J. Inazawa: The brain finger protein gene (ZNF179), a member of the ring finger family, maps within the Smith-Magenis syndrome region at 17p11.2. Amercan Journal of Medical Genetics 69:320-324 ,1997
  385. Y. Nakamura, Cleaning up on β-catenin. (News & Views) Nature Medicine 3:499-500,1997
  386. Y. Miki, T. Katagiri, and Y. Nakamura: Infrequent Mutation of the H-cadherin Gene on Chromosome 16q24 in Human Breast Cancers. Jpn. J. Cancer Research 88:701-704 ,1997
  387. S. Takeda, T. Fujiwara, F. Shimizu, A. Kawai, K. Shinomiya, S. Okuno, K. Ozaki, T. Katagiri, Y. Shimada, M. Nagata, T. Watanabe, A. Takaichi, Y. Kuga, M. Shimizu, H. Hishigaki, E. Takahashi, S. Shin, Y. Nakamura, and Y. Hirai: Isolation and mapping of karyopherin alpha3 (KPNA3), a human gene that is highly homologous to genes encoding Xenopus importin, yeast SRP1 and human RCH1 Cytogenetics Cell Genetics 76:87-93 ,1997
  388. S. Fukuda , H. Kohsaki, S. Hayashi, K.Ozaki, T.Kuroki ,T. Yamori, T. Tsuruo, S. Nakamori, S. Imaoka and Y. Nakamura: Isolation of a novel gene showing a reduced expression in metastatic colorectal carcinoma cell lines and carcionmas. Jpn. J. Cancer Research 88:725-731 ,1997
  389. F. Shimizu , T.K. Watanabe, S. Okuno, Y. Omori, T. Fujiwara, E. Takahashi, and Y. Nakamura: Isolation of a novel human cDNA (rhoHP1) homologous to rho genes. Biochem. Biophy. Acta 1352:13-16 ,1997
  390. H. Chen , C. Rossier, Y. Nakamura, A. Lynn, A. Chakravarti, and S. Antonarakis: Cloning of a novel homeobox-containing gene, PKNOX1, and mapping to human chromosome 21q22.3. Genomics 41:193-200 ,1997
  391. T. Urano , H. Nishimori, H.-J. Han, T. Furuhata, Y. Kimura, Y. Nakamura and T. Tokino: Cloning of P2XM, a novel human P2X receptor gene regulated by p53. Cancer Research 57:3281-3287 ,1997
  392. H. Nishimori , T. Shiratsuchi, T. Urano, Y. Kimura, K. Kiyono, K. Tatsumi, S. Yoshida, M. Ono, M. Kuwano, Y. Nakamura, T. Tokino: A novel brain-specific p53-target gene, BAI1, containing thrombospondin type1 repeats inhibits experimental angiogenesis. Oncogene 15:2145-2150 ,1997
  393. S. Nakamori , M. Kameyama, H. Furukawa, O. Takeda, S. Sugai, S. Imaoka, and Y. Nakamura: Detection of colorectal cancer cells in circulation and lymph nodes. Diseases of Colon and Rectum 10:29-36 ,1997
  394. M. Nesbit , M. Hodges, L. Campbell, T. de Meulemeester, M. Alders, N. Rodrigues, K. Talbot, A. Theodosiou, M. Mannens, Y. Nakamura, P. Little, and K.E. Davies: Genomic organization and chromosomal localization of a member of the MAP kinase phosphatase gene family to human chromosome 11p15.5 and a pseudogene to 10q11.2. Genomics 42:284-294 ,1997
  395. F. Shimizu , T. Katagiri, M. Suzuki, T.K. Watanabe, S. Okuno, Y. Kuga, M. Nagata, T. Fujiwara, Y. Nakamura and E. Takahashi: Cloning and chromosome assignment to 1q32 of a human cDNA (RAB7L1) encoding a small GTP-binding protein, a member of the RAS superfamily. Cytogenetics Cell Genetics 77:261-267 ,1997
  396. H. Shibata, K. Toyama, H. Shioya, M. Ito, M. Hirota, S. Hasegawa, H. Matsumoto, H. Takano, T. Akiyama, K. Toyoshima, R. Kanamaru, Y. Kanegae, I. Saito, Y. Nakamura, K. Shiba, and T. Noda: Rapid colorectal adenoma formation initiated by conditional targeting of the APC gene. Science 278:120-123 ,1997
  397. S. Ikegawa , Y. Nakamura: Structure of the gene encoding human colligin-2 (CBP2). Gene 194:301-303 ,1997
  398. T. Yokota , S. Matsumoto, M. Yoshimoto, F. Kasumi, F. Akiyama, G. Sakamoto, Y. Nakamura, and M. Emi: Mapping of a breast cancer tumor supressor gene locus to a 4-cM interval on chromosome 18q21. Jpn. J. Cancer Research 88:959-964 ,1997
  399. M. Nakamoto , H. Takebayashi, A. Kakizuka, Y. Kawaguchi, S. Narumiya, M. Taniwaki, Y. Nakamura, K. Ishikawa, I. Akiguchi, and J. Kimura: A CAG/CTG expansion in the normal population. Nature Genetics 17:385-386 ,1997
  400. Y. Nakamura, T. Tokino, M. Isomura, J. Inazawa, T. Aoki, T. Mori, M. Shimada, K. Miura, and K. Suzuki: Multistep carcinogenesis of Esophageal CarcinomaMolecular Pathology of Gastroenterological Cancer :15-22 ,1997
  401. M. Emi, S. Matsumoto, A. Iida, K. Tsukamoto, T. Nakata, T. Yokota, F. Akiyama, G. Sakamoto, M. Yoshimoto, F. Kasumi, and Y. Nakamura: Correlation of allelic losses and clinicopathological factors in primary breast cancers. Breast Cancer 4:243-247,1997
  402. F. Shimizu, T.K. Watanabe, H. Shimomiya, Y. Nakamura, and T. Fujiwara: Isolation and expression of a cDNA for human brain fatty acid-binding protein (B-FABP). Biochem. Biophy. Acta, 1354:24-28, 1997
  403. F. Hosoda , Y. Arai, E. Kitamura, J. Inazawa, M. Fukushima, T. Tokino, Y. Nakamura, C. Jones, N. Kakazu, T. Abe, and M. Ohki: A complete NotI restriction map covering the entire long arm of human chromosome 11. Genes to Cells 2:345-357 ,1997
  404. Y. Takahashi , H.Fujita, Y. Nakamura, and H. Kurahashi: Dual-color FISH analysis of Robertsonian translocations, Jpn. J. Human Genetics 42:517-523 ,1997
  405. Y. Yamane , Y. Nakamura, and M. Isomura: Allelic frequencies of twelve dinucleotide repeat marker loci on chromosome 13 in normal Japanese population. Jpn. J. Human Genetics 42:533-537 ,1997
  406. Y. Takei , S. Sasaki, T. Fujiwara, E. Takahashi, T. Muto and Y. Nakamura: Molecular cloning of a novel gene homologous to myeloid antigen CD33 and its specific expression in placenta. Cytogenetics Cell Genetics 78:295-300 ,1997
  407. Y. Ohmori , H. Kyushiki, S. Takeda, M. Suzuki, A. Kawai, T. Fujiwara, E. Takahashi and Y. Nakamura : Cloning, expression, and mapping of a novel human zinc-finger gene TCF17 homologous to rodent Kid1. Cytogenetics Cell Genetics 78:285-288 ,1997
  408. K. Kagawa , T. Inoue, T. Tokino, Y. Nakamura, and T. Akiyama: Overexpression of GML promotes radiation-induced cell cycle arrest and apoptosis. Biochem. Biophy. Research Comm. 241:481-485 ,1997
  409. T.K. Watanabe, M. Suzuki, Y. Omori, H. Hishigaki, M. Horie, N. Kanemoto, T. Fujiwara, Y. Nakamura, and E. Takahashi: Cloning and characterization of a novel member of the human mad gene family. Genomics 42:446-451 ,1997

    1998　　↑ページトップへ

  410. T. Shiratsuchi, H. Nishimori, H. Ichise, Y. Nakamura, and T. Tokino: Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1). Cytogenetics Cell Genetics 79:103-108 ,1998
  411. S. Ishikawa , M. Kai, Y. Murata, M. Tamari, Y. Daigo, T. Murano, M. Ogawa, and Y. Nakamura: Genomic organization and mapping of the human activin receptor type IIB (hActR-IIB) gene, Journal of Human Genetics 43:132-134 ,1998
  412. H. Nagase , Y. Nakamura: Cleavage using Rnase to detect mutations. Mutation Detection :63-80 ,1998
  413. M. Itoh, S. Tsukada, T. Orita, J. Nishiu, H. Tomoike, and Y. Nakamura, and T. Tanaka: Identification by differential display of eight known genes induced during in vivo endothelial proliferation. Journal of Human Genetics 43:9-13,1998
  414. M. Matsushima, T. Fujiwara, E. Takahashi, T. Minaguchi, Y. Eguchi, Y. Tsujimoto, K. Suzumori, Y. Nakamura: Isolation and functional analysis of a novel human cDNA (BNIP3L) encoding a protein homologous to human Nip3. Genes Chromosomes and Cancer 21:230-235 ,1998
  415. T. Katagiri, F. Kasumi, M. Yoshimoto, K. Asaishi, R. Abe, A. Tsuchiya, M. Sugano, T. Nomizu, S. Takai, M. Yoneda, K. Nanba, M. Makita, H. Okazaki, K. Hirata, M. Okazaki, Y. Furutsuma, Y. Morishita, Y. Iino, T. Karino, T. Fukutomi, H. Ayabe, S. Hara, T. Kajiwara, S. Houga, T. Shimizu, M. Toda, Y. Yamasaki, T. Uchida, K. Kunitomo, H.Sonoo, J. Kurebayashi, K. Shimotuma, Y. Nakamura, and Y. Miki: High proportion of missense mutations of the BRCA1 and BRCA2 genes in Japanese breast cancer families. Journal of Human Genetics 43:42-48 ,1998
  416. A. Okawa, S. Ikegawa, I. Nakamura, S. Goto, H. Moriya, and Y. Nakamura: Mapping of a gene responsible for twy (tip-toe walking Yoshimura), a mouse model of ossification of the posterior longitudinal ligament of the spine (OPLL). Mammalian Genome 9:155-156 ,1998
  417. K. Ueda , M. Nishijima, H. Inui, M. Watatani, E. Yayoi, J. Okamura, M. Yasutomi, Y. Nakamura, and Y. Miyoshi: Infrequent mutations in the PTEN/MMAC1 gene among primary breast cancers. Jpn. J. Cancer Research 89:17-21 ,1998
  418. S. Shirahama , K. Ogura, H. Takami, K. Ito, T. Tohsen, A. Miyauchi, and Y. Nakamura: Mutational analysis of the RET proto-oncogene in 71 Japanese patients with medullary thyroid carcinoma. Journal of Human Genetics 43:101-106 ,1998
  419. K. Ozaki, M. Nagata, M. Suzuki, T. Fujiwara, Y. Miyoshi, O. Ishikawa, H. Ohigashi, S. Imaoka, E. Takahashi, and Y. Nakamura: Isolation and characterization of a novel human pancreas-specific gene, "pancpin", that is down-regulated in pancreatic cancer cells. Genes Chromosomes and Cancer 22:179-185 ,1998
  420. H. Nakagawa , K. Koyama, T. Tanaka, Y. Miyoshi, H. Ando, S. Baba, M. Watatani, M. Yasutomi, M. Monden, and Y. Nakamura: Localization of the gene responsible for Peutz-Jeghers syndrome within a 6-cM region of chromosome 19p13.3. Human Genetics 102:203-206,1998
  421. J. Nisiu , T. Tanaka, and Y. Nakamura: Isolation and chromosomal mapping of the humanhomolog of perilipin, a rat adipose tissue-specific gene by differential dsplay method. Genomics 48:254-257 ,1998
  422. K. Mori , K. Iwao, Y. Miyoshi, A. Nakagawara, K. Kofu, T. Akiyama, N. Arita, T. Hayakawa and Y. Nakamura: Identification of brain-specific splicing variants of the hDLG1 gene and altered splicing in neuroblastoma cell lines. Journal of Human Genetics 43:123-127 ,1998
  423. T. Itoh , T. Tanaka, R. Nagai, T. Kamiya, T. Sawayama, T. Nakayama, H. Tomoike, H. Sakurada, Y.Yazaki, and Y. Nakamura: Genomic organization and mutational analysis of HERG, a gene responsible for familial long QT syndrome. Human Genetics 102:435-439,1998
  424. M. Emi, M. Matsushima, T. Katagiri, T. Yokota, T. Nakata, F. Kasumi, Y. Miki, M.H. Skolnick and Y. Nakamura: Multiplex mutation screening of the BRCA1 gene in 1000 Japanese breast cancers: 2-3 % of Japanese breast cancer is attributable to BRCA1 mutations. Jpn. J. Cancer Research 89:12-16,1998
  425. A. Iida, K. Kurose, R. Isobe, F. Akiyama, G. Sakamoto, M. Yoshimoto, F. Kasumi, Y. Nakamura, and M. Emi: Mapping of a new target region of allelic loss to a 2-cM interval at 22q13.1 in primary breast cancer. Genes Chromosomes and Cancer 21:108-112 ,1998
  426. T. Nakata, M. Yoshimoto, F. Kasumi, F. Akiyama, G. Sakamoto, Y. Nakamura, and M. Emi: Identification of a new commonly deleted region within a 2-cM interval of 11p11 in breast cancers. Europian Journal of Cancer 34:417-421 ,1998
  427. K. Tsukamoto , N. Itoh, M. Yoshimoto, F. Kasumi, F. Akiyama, G. Sakamoto, Y. Nakamura, and M. Emi: Allelic loss on chromosome 1p is associated with progression and lymph node metastasis of primary breast carcinoma. Cancer 82:317-322 ,1998
  428. T. Katagiri, H. Saito, A. Shinohara, H. Ogawa, N. Kamada, Y. Nakamura, and Y. Miki : Multiple possible sites of BRCA2 interacting with DNA repair protein Rad51. Genes Chromosomes and Cancer 21:217-222 ,1998
  429. K. Iwao , S. Nakamori, M. Kameyama, S. Imaoka, M. Kinoshita, T. Fukui, S. Ishiguro, Y. Nakamura, and Y. Miyoshi: Activation of the β-catenin gene by interstitial deletions involving exon 3 in primary colorectal carcinomas without APC mutations. Cancer Research 58:1021-1026 ,1998
  430. S. Yamamoto , M. Okada, M. Tsujikawa, Y. Shimomura, K. Nishida, Y. Inoue, H. Watanabe, N. Maeda, H. Kurahashi, S. Kinoshita, Y. Nakamura, and Y. Tano: Kerato-epithelin mutation in Lattice corneal dystrophy type IIIA. Am. J. Human Genetics 62:719-722 ,1998
  431. N. Kanemoto , H. Hishigaki, A. Miyakita, K. Oga, S. Okuno, A. Tsuji, T. Takagi, E. Takahashi, Y. Nakamura, and T. K. Watanabe:Genetic dissection of "OLETF", a rat model for non-insulin dependent diabetes mellitus. Mammalian Genome 9:419-425 ,1998
  432. Y. Takei , S. Ishikawa, T. Tokino, T. Muto and Y. Nakamura: Isolation of a novel p53-target gene from a colon-cancer cell line carrying a highly-regulated wild-type p53 expression system. Genes Chromosomes and Cancer 23:1-9,1998
  433. H.-J. Han, T. Tokino and Y. Nakamura: CSR, a scavenger receptor-like gene with a protective role from cell death caused by UV irradiation and oxidative stress. Human Molecular Genetics 7:1039-1046 ,1998
  434. M. Fujimoto , P.N. Kantaputra, S. Ikegawa, Y. Fukushima, S. Sonta, M. Matsuno, T. Ishida, T. Matsumoto, S. Kondo, H. Tomita, H.-X. Deng, M. D'urso, M.M. Rinaldi, V. Ventroto, T. Takagi, Y. Nakamura, and N. Niikawa: The gene for mesomeric dysplasia Kantaputra type is mapped to chromosome 2q24-q32. Journal of Human Genetics 43:32-36 ,1998
  435. H. Kurahashi , M. Sakamoto, J. Ono, A. Honda, S. Okada, and Y. Nakamura: Molecular cloning of chromosomal breakpoint in the LIS1 gene in a balanced t(8;17) patient with an isolated lissencephaly. Human Genetics 103:189-192 ,1998
  436. T. Aihara , Y. Miyoshi, K. Koyama, M. Suzuki, E. Takahashi, M. Monden, and Y. Nakamura: Cloning and mapping of hSNF2h, a novel human homologue of Drosophila ISWI. Cytogenetics Cell Genetics 81:191-193 ,1998
  437. Y. Yamane , K. Kogawa, T. Tanaka, Y. Nakamura, and M. Isomura: Heterozygosities and allelic frequencies of 358 dinucleotide-repeat marker loci in the Japanese population. Journal of Human Genetics 43:165-168 ,1998
  438. S. Saito, M. Matsushima, S. Sirahama, T. Minaguchi, Y. Kanamori, M. Minami and Y. Nakamura: Complete genomic structure, DNA polymorphisms, and alternative splicing of the human AF-6 Gene. DNA Research 5:115-120 ,1998
  439. T. Shiratsuchi, M. Futamura, K. Oda, H. Nishimori, Y. Nakamura, and T. Tokino: Cloning and characterization of BAP1 (BAI-associated protein 1): a PDZ domain-containing protein that interacts with BAI1. Biochem. Biophy. Research Comm. 247:597-604 ,1998
  440. H. Nakagawa , K. Koyama, Y. Miyoshi, H. Ando, S. Baba, M. Watatani, M. Yasutomi, N. Matsuura, M. Monden, and Y. Nakamura: Nine Novel Germline Mutations of STK11 in Ten Families with Peutz-Jeghers Syndrome. Human Genetics 103:168-172 ,1998
  441. T. Itoh , T. Tanaka, R. Nagai, K, Kikuchi, S. Ogawa, S. Okada, S. Yamagata, K. Yano, Y. Yazaki, and Y. Nakamura: Genomic organization and mutational analysis of KVLQT1, a gene responsible for familial long QT syndrome. Human Genetics 103:290-294 ,1998
  442. Y. Miyoshi, K. Iwao, Y. Nagasawa, T. Aihara, Y. Sasaki, S. Imaoka, M. Murata, T. Shimano, and Y. Nakamura: Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3. Cancer Research 58:2524-2527 ,1998
  443. H.-J. Han, Y. Nakamura: Dinucleotide repeat polymorphism in the first intron of the CSR gene. Journal of Human Genetics 43:212-213 ,1998
  444. Y. Nakamura, K. Koyama, and M. Matsushima: VNTR (variable number of tandem repeat) sequences as transcriptional, translational, or functional regulators. Journal of Human Genetics 43:149-152 ,1998
  445. S. Matsuura , H. Tauchi, A. Nakamura, N. Kondo, S. Sakamoto, D. Smeets, C. Weemaes, B.H. Belohradsky, M Oshimura, M Isomura, Y. Nakamura and K. Komatsu: The gene for Nijmegen breakage syndrome, the ataxia-telangiectasia variant, encodes a novel protein without homology to ATM. Nature Genetics 19:179-181 ,1998
  446. K. Bando , S. Matsumoto, M. Onda, F. Akiyama, G. Sakamoto, M. Yoshimoto, F. Kasumi, Y. Nakamura, and M. Emi: Frequent allelic loss at 6q26-27 in breast carcinomas of the solid-tubular histologic type. Breast Cancer 5:127-130 ,1998
  447. T. Aihara , S. Noguchi, Y. Miyoshi, H. Nakano, Y. Sasaki, Y. Nakamura, and S. Imaoka: Allelic imbalance of insulin-like growth factor II gene expression in cancerous and precancerous lesions of the liver. Hepatology 28:86-89 ,1998
  448. O. Maruyama , H. Nishimori, T. Katagiri, Y. Miki, A. Ueno, and Y. Nakamura: Cloning of PPS encoding a novel human basic Helix-Loop-Helix motif protein that is specifically expressed in primary spermatocytes at the pachytene stage. Cytogenetics Cell Genetics 82:41-48 ,1998
  449. A. Okawa, I. Nakamura, S. Goto, H. Moriya, Y. Nakamura, and S. Ikegawa: Nonsense mutation of nucleotide pyrophosphatase in ttw (tip-toe walking), a mouse model of ossification of the posterior longitudinal ligament of the spine (OPLL). Nature Genetics 19:271-273 ,1998
  450. M.Tamari , Y. Daigo, S, Ishikawa, and Y. Nakamura: Genomic structure of a novel human gene on chromosome 3p22-21.3 encoding a xylulokinase-like protein. Cytogenetics Cell Genetics 82:101-104 ,1998
  451. T. Nakajima , T. Furukawa, T. Tanaka, Y. Katayama, R. Nagai, Y. Nakamura, and M. Hiraoka: A novel mechanism of HERG current suppression in LQT2: shift in voltage-dependent of HERG inactivation. Circulation Research 83:415-422 ,1998
  452. K. Ohgaki, A. Iida, F. Kasumi, G. Sakamoto, M. Akimoto, Y. Nakamura, and M. Emi: Mapping of a new target region of allelic loss to a 6-cM interval at 21q21 in primary breast cancers. Genes Chromosomes and Cancer 23:244-247 ,1998
  453. K. Kobayashi , Y. Nakahori, K. Mizuno, M. Miyake, Y. Nakamura, K. Tokunaga and T. Toda: Founder-haplotype analysis in Fukuyama-type congenital muscular dystrophy (FCMD). Human Genetics 108:323-327 ,1998
  454. T. Fujiwara , A. Saito, M. Suzuki, H. Shinomiya, T. Suzuki, E. Takahashi, A. Tanigami, A. Ichiyama, C. H. Chung, Y. Nakamura, and K. Tanaka: Identification and cromosomal assignment USP1, a novel gene encoding a human ubiquitin-specific protease. Genomics 54:155-158 ,1998
  455. K. Kurose, A. Iida, T. Araki, G. Sakamoto, F. Kasumi, Y. Nakamura, and M. Emi: Frequent alleleic loss at 7p14-15 associated with aggressive histologic types of breast cancer. Jpn. J. Cancer Research 89:533-538 ,1998
  456. K. Lu H. Nishimori, Y. Nakamura, K. Shima, M. Kuwajima: A missense mutation of mouse OCTN2, a sodium-dependent carnitine cotransporter, is the juvenile visceral steatosis mouse. Biochem. Biophy. Research Comm., 252:590-594, 1998
  457. K. Kobayashi , Y. Nakahori, M. Miyake, Y. Nomura, M. Yoshioka, K. Saito, M. Osawa, J. Goto, Y. Nakagome, I. Kanazawa, Y. Nakamura, K. Tokunaga, and T. Toda: Ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy (FCMD). Nature 394:388-392 ,1998
  458. K. Ozaki, T. Fujiwara, Y. Nakamura, and E. Takahashi: Isolation and mapping of a novel human kidney - and liver- specific gene homologous to the bacterial acetyltransferase. Journal of Human Genetics 43:255-258 ,1998
  459. S. Okamoto , M. Matsushima and Y. Nakamura: Identification, genomic organization, and alternative splicing of KNSL3, a novel human gene encoding a kinesin-like protein. Cytogenetics Cell Genetics 83:25-29 ,1998
  460. J. Nishiu , T. Tanaka, and Y. Nakamura; Identification of a novel gene (FECM) encoding a putative extracellular matrix protein expressed predominantly in adipose and female-specific tissues. Genomics 52:378-381 ,1998
  461. K. Ozaki, M. Nagata, M. Suzuki, T. Fujiwara, K. Ueda, Y. Miyoshi, E. Takahashi, and Y. Nakamura: Isolation and characterization of a novel human lung-specific gene homologous to lysosomal membrane glycoprotein-1 and -2; significantly increased expression in several types of human cancers. Cancer Research 58:3499-3503 ,1998
  462. Y. Ohmori , M. Suzuki, K. Ozaki, Y. Harada, Y. Nakamura, E. Takahashi, and T. Fujiwara: Expression and chromosomal localization of KIAA0369, a putative kinase structually related to Doublecortin. Journal of Human Genetics 43:169-177 ,1998
  463. Y. Ariyama , Y. Fukuda, Y. Okuno, M. Seto, K. Date, T. Abe, Y. Nakamura, and J. Inazawa: Amplification on double-minute chromosome and partial-tandem duplication of the MLL gene in leukemic cells of a patient with acute myelogenous leukemia. Genes Chromosomes and Cancer 23:267-272 ,1998
  464. T. Nishiwaki , Y. Daigo, M. Tamari, Y.Fujii, and Y. Nakamura: Molecular cloning, mapping, and characterization of two novel human genes, ORCTL3 and ORCTL4, bearing homology to organic-cation transporters. Cytogenetics Cell Genetics 83:251-255 ,1998
  465. M. Sakamoto , J. Ono, S. Okada, M. Masuno, Y. Nakamura, and H. Kurahashi: Alteration of the LIS1 gene in Japanese patients with isolated lissencephaly sequence or Miller-Dieker syndrome. Human Genetics 103:586-589 ,1998
  466. M. Tsujikawa , H. Kurahashi, T. Tanaka, M. Okada, S. Yamamoto, N. Maeda, H. Watanabe, Y. Inoue, A. Kiridoshi, K. Matsumoto, Y. Ohishi, S. Kinishita, Y. Shimomura, Y. Nakamura, and Y. Tano: Homozygosity mapping of a gene responsible for gelatinous drop-like corneal dystrophy (GDLD) to chromosome 1p. Am. J. Human Genetics 63:1073-1077 ,1998
  467. T. Minaguchi , Y. Kanamori, M. Matsushima, H. Yoshikawa, Y. Taketani, and Y. Nakamura: No evidence of correlation between polymorphism at codon 72 of p53 and risk of cervical cancer in Japanese patients with HPV16/18 infection. Cancer Research 58:4585-4586 ,1998
  468. S. Ikegawa , H. Ohashi, K. C. Kim, A. Sannohe, G. Nishimura, M. Kimizuka, Y. Fukushima, T. Nagai, Y. Nakamura: Recurrent and Novel Mutations of COMP (cartilage oligomeric matrix protein) in Pseudoachondroplasia and Multiple Epiphyseal Dysplasia. Human Genetics 103:633-638 ,1998
  469. H. Nakagawa , Y. Murata, K. Koyama, A. Fujiyama, Y. Miyoshi, M. Monden, T. Akiyama, and Y. Nakamura: Identification of a brain-specific APC homologue, APCL, and its interaction with β-catenin. Cancer Research 58:5176-5181 ,1998
  470. Y. Nakamura, J. Inazawa: Genetic diagnosis of cancer. (review) Int. J. Clin. Oncology, 3:265-270 ,1998
  471. Y. Nakamura, ATM: the p53 booster. Nature Medicine 4:231-1232 ,1998
  472. T. Shiratsuchi, K. Oda, H. Nishimori, M. Suzuki, E. Takahashi, T. Tokino, and Y. Nakamura: Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1. Biochem. Biophy. Research Comm. 251:158-165 ,1998
  473. Y. Miyoshi, K. Iwao, G. Nawa, H.Yoshikawa, T. Ochi, and Y. Nakamura: Frequent mutations in the -catenin gene in desmoid tumors from patients without familial adenomatous polyposis. Oncology Research 10:591-594 ,1998
  474. S. Ikegawa , G. Nishimura, T. Nagai, T. Hasegawa, H. Ohashi, Y. Nakamura: Mutation of the type X collagen gene (COL10A1) causes spondylometaphyseal dysplasia. Am. J. Human Genetics 63:1659-1662 ,1998
  475. G. Nawa, T. Urano, T. Tokino, T. Ochi, Y. Miyoshi: Cloning and characterization of the murine P2XM receptor gene. Journal of Human Genetics, 43:262-267, 1998

    1999　　↑ページトップへ

  476. K. Oda, T. Shiratsuchi, H. Nishimori, J. Inazawa, H. Yoshikawa, Y. Taketani, Y. Nakamura, T. Tokino: Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1. Cytogenetics Cell Genetics, 84:75-82, 1999
  477. H. Tauchi, S. Matsuura, M. Isomura, T. Kinjo, A. Nakamura, S. Sakamoto, N. Kondo, S. Endo, K. Komatsu, and Y. Nakamura: Sequence analysis of an 800-kb genomic DNA region on chromosome 8q21 that contains the Nijmegen breakage syndrome gene, NBS1. Genomics, 55:242-247, 1999
  478. T. Yokota, M. Yoshimoto, F. Akiyama, G. Sakamoto, F. Kasumi, Y. Nakamura, and M. Emi: Localization of a tumor suppressor gene associated with the progression of human breast carcinoma within a 1-cM interval of 8p22-p23.1. Cancer, 85:447-452, 1999
  479. T. Katagiri, M. Futamura, and Y. Nakamura: A Gln/Arg polymorphism at codon 349 of the hBUBR1 gene. Journal of Human Genetics, 44:131-132, 1999
  480. K. Iwao, Y. Miyoshi, G. Nawa, H. Yoshikawa, T. Ochi, and Y. Nakamura: Frequent beta-catenin abnormalities in bone and soft-tissue tumors. Jpn. J. Cancer Research, 90:205-209, 1999
  481. K. Kyo, M. Parkes, Y. Takei, H. Nishimori, H. Nagawa, S. Baba, T. Muto, G. M. Lathrop, Y. Nakamura: Association of ulcerative colitis with rare VNTR alleles of the human intestinal mucin gene, MUC3. Human Molecular Genetics, 8:307-311, 1999
  482. I. Smith, M.A. Narang, T. Evans, C. Heimann, Y. Nakamura, G. Chenevix-Trech, T. Pietsvh, C. Wicking, and B.J. Wainwright: Isolation and characterization of human Patched 2 (PTCH2), a putative tumor suppressor gene in basal cell carcinoma and medulloblastoma on chromosome 1p32. Human Molecular Genetics, 8:291-297, 1999
  483. M. Tamari, Y. Daigo, and Y. Nakamura: Isolation and characterization of a novel serine threonine kinase gene on chromosome 3p22-21.3. Journal of Human Genetics, 44:116-120, 1999
  484. G. Nawa, Y. Miyoshi, H. Yoshikawa, T. Ochi, and Y. Nakamura: Frequent loss of expression or aberrant alternative splicing of P2XM, a p53-inducible gene, in soft-tissue tumors. British Journal of Cancer, 80:1185-1189, 1999
  485. T. Watanabe, M.-T. Bihoreau, L. C. McCarthy, S. L. Kiguwa, H. Hishigaki, A. Tsuji, J. Browne, Y.Yamasaki, A, Mizoguchi-Miyakita, K. Oga, T. Ono, S. Okuno, N. Kanemoto, E. Takahashi, H. Hayashi, M. Adachi, C. Webber, M. Davis, S.Kiel, C. Knights, A. Smith, R. Critcher, J. R. Hudson, Jr., T. Day, Y. Irie, T. Takagi, Y. Nakamura, P. N. Goodfellow, G. M. Lathrop, A. Tanigami, and M. R. James: A radiation hybrid map of the rat genome containing 5,255 markers. Nature Genetics, 22:27-36, 1999
  486. I. Nakamura, A. Okawa, S. Ikegawa, K. Takaoka and Y. Nakamura: Genomic organization, mapping, and polymorphisms of the gene encoding human cartilage intermediate layer protein (CILP). Journal of Human Genetics, 44:203-205, 1999
  487. Y. Daigo, M. Isomura, T. Nishiwaki, M. Tamari, S. Ishikawa, M. Kai, Y. Murata, K. Takeuchi, Y. Yamane, R. Hayashi, M. Minami, M. A. Fujino, Y. Hojo, I. Uchiyama, T. Takagi, and Y. Nakamura: Characterization of a 1,200-kb genomic segment of chromosome 3p22-p21.3. DNA Research, 6:37-44, 1999
  488. T. Imazu, S. Shimizu, S. Tagami, M. Matsushima, Y. Nakamura, T. Miki, A. Okuyama, and Y. Tsujimoto: Bcl-2/E1B 19 kDa-interacting protein 3-like protein (Bnip3L) interacts with Bcl-2/Bcl-XL and induces apoptosis by altering mitochondrial membrane permiability. Oncogene, 18:4523-4529, 1999
  489. O. Watanabe, K. Natori, M. Tamari, Y.Shiomoto, S.Kubo, and Y. Nakamura: Significantly elevated expression of PF4 (platelet factor 4) and eotaxin in the NOA mouse, a model for atopic dermatitis. Journal of Human Genetics, 45:173-176, 1999
  490. S. Ikegawa, M. Isomura, Y. Koshizuka and Y. Nakamura: Cloning and characterization of ASH2L and Ash21, human and mouse homologs of the Drosophila ash2 gene. Cytogenetics Cell Genetics, 84:167-172, 1999
  491. M. Futamura, H. Nishimori, T. Shiratsuchi, S. Saji, Y. Nakamura, T. Tokino: Molecular cloning, mapping, and characterization of a novel human gene, MTA1-L1, showing homology to a metastasis-associated gene, MTA1. Journal of Human Genetics, 44:52-56, 1999
  492. M. Tsujikawa, H. Kurahashi, T. Tanaka, K. Nishida, Y. Shimomura, Y. Tano, and Y. Nakamura: Identification of the gene responsible for gelatinous drop-like corneal dystrophy. Nature Genetics, 21:420-423, 1999
  493. Y. Daigo, T. Nishiwaki, T. Kawasoe, M. Tamari, E. Tsuchiya, and Y. Nakamura: Molecular cloning of a candidate tumor suppressor gene, DLC1, from chromosome 3p21.3. Cancer Research, 59:1966-1972, 1999
  494. T. Nishiwaki, Y. Daigo, T. Kawasoe, Y. Nagasawa, H. Ishiguro, M. Fujita, Y. Furukawa and Y. Nakamura: Isolation and characterization of a human cDNA homologous to the Xenopus laevis XCAP-C gene belonging to the structural maintenance of chromosomes (SMC) family. Journal of Human Genetics, 44:197-202, 1999
  495. T. Sakabe, T. Shinomiya, T. Mori, Y. Ariyama, Y. Fukuda, T. Fujiwara, Y. Nakamura, and J. Inazawa: Identification of a novel gene, MASL1, within an amplicon at 8p23.1 detected in malignant fibrous histiocytomas by comparative genomic hybridization. Cancer Research, 59:511-515, 1999
  496. C. Sakakura, T. Mori, T. Sakabe, Y. Ariyama, T. Shinomiya, K. Date, A. Hagiwara, T. Yamaguchi, T. Takahashi, Y. Nakamura, T. Abe, and J. Inazawa: Gains, losses, and amplification of genomic materials in primary gastric cancers analyzed by comparative genomic hybridization. Genes Chromosomes and Cancer, 24:299-305, 1999
  497. T. Shinomiya, T. Mori, Y. Ariyama, T. Sakabe, Y. Fukuda, Y. Murakami, Y. Nakamura, and J. Inazawa: Comparative genomic hybridization of squamous cell carcinomas of the esophagus: the possible involvement of the DPI gene in the 13q34 amplicon. Genes Chromosomes and Cancer, 24:337-344, 1999
  498. K. Fukino, A. Iida, A. Teramoto, G. Sakamoto, F. Kasumi, Y. Nakamura and M. Emi: Frequent allelic loss at the TOC locus on 17q25.1 in promary breast cancers. Genes Chromosomes and Cancer, 24:345-350, 1999
  499. T. Minaguchi, M. Matsushima, S. Saito, Y. Kanamori, S. Shirahama, S. Okamoto, M. Minami, Y. Taketani, and Y. Nakamura: Complete DNA sequence and characterization of a 330-kb VNTR-rich region on chromosome 6q27 that is commonly deleted in ovarian cancer. DNA Research, 6:131-136, 1999
  500. T. Mori, Y. Fukuda, H. Kuroda, T. Matsumura, S. Ota, T. Sugimoto, Y. Nakamura, and J. Inazawa: Cloning and characterization of a novel rab-family gene, Rab36, within the region at 22q11.2 that is homozygously deleted in malignant rhabdois tumors. Biochem. Biophy. Research Comm., 254:594-600, 1999
  501. H. Nakagawa, K. Koyama, S. Nakamori, M. Kameyama, S. Imaoka, M. Monden, Y. Nakamura: Frameshift mutation of the STK11 gene in a sporadic gastrointestinal cancer with microsatellite instability. Jpn. J. Cancer Research, 90:633-637, 1999
  502. M. Emi, M. Yoshimoto, T. Sato, S. Matsumoto, T. Iwase, I. Ito, K. Minobe, T. Tada, T. Katagiri, K. Bando, F. Akiyama, Y. Harada, K. Fukino, G. Sakamoto, M. Matsushima, A. Iida, H. Saito, F. Kasumi and Y. Nakamura: Allelic losses at 1p34, 13q12, 17p13.3 and 17q21.1 correlates with poor postoperative prognosis in breast cancer. Genes Chromosomes and Cancer, 26:134-141, 1999
  503. K. Ueda, Y. Miyoshi, T. Tokino, M. Watatani, and Y. Nakamura: Induction of apoptosis in T98G glioblastoma cells by transfection of GML, a p53-target gene. Oncology Research, 11:125-132, 1999
  504. S. Ikegawa, M. Masuno, Y. Kumano, A. Okawa, M. Isomura, K. Koyama, K. Okui, K. Imaizumi, and Y. Nakamura: Cloning of translocation breakpoints associated with Shwachman syndrome and identification of a candidate gene. Clinical Genet., 55:466-472, 1999
  505. I. Nakamura, S. Ikegawa, A. Okawa, S. Okuda, Y. Koshizuka, H. Kawaguchi, K. Nakamura, T. Koyama, S. Goto, J. Toguchida, M. Matsushita, T. Ochi, K.Takaoka, and Y. Nakamura: Association of the human NPPS gene with ossification of the posterior longitudinal ligament of the spine (OPLL). Human Genetics, 104:492-497, 1999
  506. S. Ikegawa, M. Isomura, Y. Koshizuka, and Y. Nakamura: Cloning and characterization of a novel gene (C8orf2), a human representative of a novel gene family with homology to C. elegans C42.C1.9. Cytogenetics Cell Genetics, 85:227-231, 1999
  507. Y. Nagasawa, Y, Miyoshi, K, Iwao, Y. Shinomura, Y. Matsuzawa, and Y. Nakamura: Transformation and morphological changes of murine L cells by transfection with a mutated form of β-catenin. Cancer Research, 59:3539-3542, 1999
  508. Y. Onouchi, H. Kurahashi, H. Tajiri, S. Ida, S. Okada, and Y. Nakamura: Genetic alterations in the JAG1 gene in Japanese patients with Alagille syndrome. Journal of Human Genetics, 44:235-239, 1999
  509. M. Ui, M. Takada, T. Arai, K. Matsumoto, K. Yamada, T. Nakahata, T. Nishiwaki, Y. Furukawa, T. Tokino, Y. Nakamura, and H. Iba: Retrovirus vectors designed for efficient transduction of cytotoxic or cytostatic genes. Gene Therapy, 6:1670-1678, 1999
  510. S. Ikegawa, M. Isomura, Y. Koshizuka, and Y. Nakamura: Cloning and characterization of human and mouse PROSC (proline synthetase co-transcribed) genes. Journal of Human Genetics, 44:337-342, 1999
  511. C.-C. Ng, K. Koyama, S. Okamura, H. Kondoh, Y. Takei, and Y. Nakamura: Isolation and characterization of a novel p53-inducible gene, TP53TG3. Genes Chromosomes and Cancer, 26:329-335, 1999
  512. Y. Daigo, Y. Furukawa, T. Kawasoe, M. Fujita, H. Ishiguro, S. Sugai, S. Nakamori and Y. Nakamura: Absence of genetic alteration at codon 531 of the human c-src gene in 479 advanced colorectal cancers from Japanese and Caucasian patients. Cancer Research, 59:4222-4224, 1999
  513. M. Nishizaki, T. Fujiwara, T. Tanida, A. Hizuta, H. Nishimori, T. Tokino, Y. Nakamura, M. Bouvet, J.A. Roth, and N. Tanaka: Recombinant adenovirus expressing wild-type p53 is antiangiogenic: a proposed mechanism for bystander effect. Clinical Cancer Research, 5:1015-1023, 1999
  514. H. Nakagawa, K. Koyama, M. Monden, and Y. Nakamura: Analysis of APCL, a brain-specific APC homologue, for mutations and expression in brain tumors. Jpn. J. Cancer Research, 90:982-986, 1999
  515. Y. Kanamori, M. Matsushima, T. Minaguchi, K. Kobayashi, S. Sagae, R. Kudo, N. Terakawa, and Y. Nakamura: Correlation between expression of the matrix metalloprotease-1 (MMP-1) gene in ovarian cancers and an insertion/deletion polymorphism in its promoter region. Cancer Research, 59:4225-4227, 1999
  516. Y. Daigo, M. Isomura, T. Nishiwaki, K. Suzuki, O. Maruyama, K. Takeuchi, Y. Yamane, R. Hayashi, M. Minami, Y. Hojo, I. Uchiyama, T.Takagi, and Y. Nakamura: Significant differences in the frequency of transcriptional units, types and numbers of repetitive elements, GC content, and the number of CpG islands between a 1,010-kb G-band genomic segment on chromosome 9q31.3 and a 1,200-kb R-band genomic segment on chromosome 3p21.3. DNA Research, 6:227-233, 1999
  517. T. Tanaka, and Y. Nakamura: Mutational analysis of familial long QT syndrome in Japan. Potassium Ion Channels, 103-116, 1999
  518. T. Minaguchi, T. Mori, Y. Kanamori, M. Matsushima, H. Yoshikawa, Y. Taketani, and Y. Nakamura: Growth suppression of human ovarian cancer cells by adenovirus-mediated transfer of the PTEN gene. Cancer Research, 59:6063-6067, 1999
  519. T. Yokota, M. Yoshimoto, F. Akiyama, G. Sakamoto, F. Kasumi, Y. Nakamura, M. Emi: Frequent multiplication of chromosomal region 8q24.1 associated with aggressive histologic types of breast cancers. Cancer Letters, 139:7-13, 1999
  520. C. Sakakura, A. Hagiwara, H. Taniguchi, T. Yamaguchi, H. Yamagishi, K.Koyama, Y. Nakamura, T. Abe, and J. Inazawa: Chromosomal aberations in human hepatocellular carcinomas associated with hepatitis C virus infection detected by comparative genomic hybridization. British Journal of Cancer, 80:2034-2039, 1999
  521. T. Nakajima, T. Furukawa, Y. Hirano, T. Tanaka, H. Sakurada,T. Takahashi, R. Nagai, T. Itoh, Y. Katayama, Y. Nakamura, and M. Hiraoka: Voltage-shift of the current activation in HERG S4 mutation (R534C) in LQT2. Cardiovascular Research, 44:283-293, 1999
  522. E. Kondo-Iida, K. Kobayashi, M. Watanabe, J. Sasaki, T. Kumagai, H. Koide, K. Saito, M. Ozawa, Y. Nakamura, and T. Toda: Novel mutations and genotyoe-phenotype relationships in 107 families with Fukuyama-type congenital muscular dystrophy (FCMD). Human Molecular Genetics, 8:2303-2309, 1999
  523. K. Natori, M. Tamari, O. Watanabe, Y. Onouchi, Y. Shiomoto, S. Kubo and Y. Nakamura: Mapping of a gene responsible for dermatitis of NOA (Naruto Research Institute Otsuka Atrichia) mice, an animal model of allergic dermatitis. Journal of Human Genetics, 44:372-376, 1999
  524. M. Nishihara, M. Terada, J. Kamogawa, Y. Ohashi, S. Mori, S. Nakatsuru, Y. Nakamura, and M. Nose: Genetic basis of autoimmune siladenitis in MRL/lpr lupus-pronemice. Arthritis & Rheumatism, 42:2616-2623, 1999
  525. M. Isomura, S. Ikegawa, T. Kinjo, K. Takeuchi, Y. Yamane-Tanaka, K. Kitami, and Y. Nakamura: Sequence analysis of a total of three megabases of DNA in two regions of chromosome 8p. DNA Research, 6:387-400, 1999
  526. M. Suzuki, T. Watanabe, T. Fujiwara, Y. Nakamura, E. Takahashi, and A. Tanigami: Molecular cloning, expression, and mapping of a novel human cDNA, GRP17, highly homologous to human gadd45 and murine MyD118. Journal of Human Genetics, 44:300-303, 1999
  527. A. Saito, K. Ozaki, T. Fujiwara, Y. Nakamura, and A. Tanigami: Isolation and mapping of a human lung-specific gene, TSA1902, encoding a novel chitinase family member. Gene, 239:325-331, 1999
  528. S. Nakatsuru, M. Terada, M. Nishihara, J. Kamogawa, T. Miyazaki, W.-M. Qu, K. Morimoto, C. Yazawa, H. Ogasawara, Y. Abe, K. Fukui, G. Ichien, M. Ito, S. Mori, Y. Nakamura, and M. Nose: Genetics dissection of the complex pathological manifestations of collagen disease in MRL/lpr mice. Pathology International, 49:974-982, 1999
  529. K. Minobe, K. Bando, K. Fukino, S. Soma, F. Kasumi, G. Sakamoto, K. Furukawa, K. Higuchi, M. Onda, Y. Nakamura, and M. Emi: Somatic mutation of the PTEN/MMAC1 gene in breast cancers with microsatellite instability. Cancer Letters, 144:9-16, 1999
  530. K. Tsukamoto, M. Yoshimoto, F. Kasumi, F. Akiyama, G. Sakamoto, Y. Nakamura, and M. Emi: Frequent multiplication of chromosome 1q in non-invasive and papillotubular carcinoma of the breast. Cancer Letters, 141:21-28, 1999
  531. M. Emi, Y. Utada, M. Yoshimoto, T. Sato, S. Matsumoto, T. Iwase, I. Ito, K. Minobe, T. Tada, T. Katagiri, K. Bando, F. Akiyama, Y. Harada, K. Fukino, G. Sakamoto, M. Matsushima, A. Iida, H. Saito, F. Kasumi and Y. Nakamura: Correlation of allelic loss with poor postoperative survival in breast cancer. Breast Cancer, 6:351-356, 1999
  532. S. Kunishima, T. Kojima, T. Tanaka, T. Kamiya, K. Ozawa, Y. Nakamura, and H. Saito: mapping of a gene for May-Hegglin anomaly to chromosome 22q. Human Genetics, 105:379-383, 1999
  533. S. Okamura, C. Ng Ching, K. Koyama, Y. Takei, M. Monden, and Y. Nakamura: Identification of seven genes regulated by wild-type p53 in a colon-cancer cell line carrying a well-controled wild-type p53 expression system. Oncology Research, 11:281-285, 1999
  534. T. Mori, H. Arakawa, T. Tokino, K. Mineura, and Y. Nakamura: Significant increase of adenovirus infectivity in glioma cell lines by extracellular domain of hCAR. Oncology Research, 11:513-521, 1999
  535. H. Tomita, S. Nagamitsu, K. Wakui, Y. Fukushoma, K. Yamada, M. Sadamatsu, A. Masui, T. Konishi, T. Matsuishi, M. Aihara, K. Shimizu, K. Hashimoto, H. Mineta, M. Matsushima, T. Tsujita, M. Saito, H. Tanaka, S. Tsuji, T. Takagi, Y. Nakamura, S. Nanko, N. Kato, Y. Nakane, and N. Niikawa: Paroximal kinesigenic choreoathetosis locus maps to chromosome 16p11.2-q12.1. Am. J. Human Genetics, 65:1688-1697, 1999
  536. S. Okuno, T.K. Watanabe, T. Ono, Y. Yamasaki, Y. Goto, H. Miyao, T. Asai, N. Kanemoto, K. Ogawa, A. Mizoguchi-Miyatake, T. Takagi, E. Takahashi, Y. Nakamura, and A. Tanigami: Genetic determinants of plasma triglyceride levels in (OLETF x BN) x OLETF backcross rats. Genomics, 62:350-355, 1999
  537. T.K. Watanabe, S. Okuno, K. Oga, A. Mizoguchi-Miyakita, A. Tsuji, Y. Yamasaki, H. Hishigaki, N. Kanemoto, T. Takagi, E. Takahashi, Y. Irie, Y. Nakamura, A. Tanigami: Genetic dissection of "OLETF," a rat model for non-insulin-dependent diabetes mellitus: Quantitative trait locus analysis of (OLETF x BN) x OLETF. Genomics, 58:233-239, 1999
  538. N. Ide, Y. Hata, H. Nishioka, K. Hirao, I. Yao, M. Deguchi, A. Mizoguchi, H. Nishimori, T. Tokino, Y. Nakamura, and Y. Takai: Localization of membrane-associated guanylate kinase (MAGI)-1/BAI-associated protein (BAP) 1 at tight junctions of epithelial cells. Oncogene, 18:7810-7815, 1999
  539. Y. Harada, K. Ozaki, M. Suzuki, T. Fujiwara, E. Takahashi, Y. Nakamura, A. Tanigami: Complete cDNA sequence and genomic organization of a human pancreas-specific gene homologous to Caenorhabditis elegans sel-1. Journal of Human Genetics, 44:330-336, 1999
  540. Y. Ariyama, T. Mori, T. Shinomiya, T. Sakabe, Y. Fukuda, A. Kanamaru, Y. Yamada, M. Isobe, M. Seto, Y. Nakamura, J. Inazawa: Chromosomal imbalances in adult T-cell leukemia revealed by comparative genomic hybridization: gains at 14q32 and 2p16-22 in cell lines. Journal of Human Genetics, 44:357-363, 1999

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