"Quantitative phase imaging with temporal kinetics predicts hematopoietic stem cell diversity "
Nature Communications Online 14 July 2025 doi:10.1038/s41467-025-61846-3
Assessing Blood Stem Cell Quality by Analyzing Cell Behavior in Real Time
Description
Published Article
Takao Yogo1, Yuichiro Iwamoto2, Hans Jiro Becker1, Takaharu Kimura1, Reiko Ishida1, Ayano Sugiyama-Finnis1, Tomomasa Yokomizo3, Toshio Suda4,5, Sadao Ota2, and Satoshi Yamazaki1,6,7
1Division of Cell Regulation, Center for Experimental Medicine and Systems Biology, The Institute of Medical Science, The University of Tokyo, Japan
2Research Center for Advanced Science and Technology, The University of Tokyo, Japan
3Department of Microscopic and Developmental Anatomy, Tokyo Women’s Medical University, Japan
4International Research Center for Medical Sciences, Kumamoto University, Japan
5Stem Cell Biology Institute of Hematology, Blood Diseases Hospital Chinese Academy of Medical Sciences & Peking Union Medical College, Japan
6Division of Cell Engineering, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Japan
7Laboratory for Stem Cell Therapy, Faculty of Medicine, Tsukuba University, Japan
2Research Center for Advanced Science and Technology, The University of Tokyo, Japan
3Department of Microscopic and Developmental Anatomy, Tokyo Women’s Medical University, Japan
4International Research Center for Medical Sciences, Kumamoto University, Japan
5Stem Cell Biology Institute of Hematology, Blood Diseases Hospital Chinese Academy of Medical Sciences & Peking Union Medical College, Japan
6Division of Cell Engineering, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Japan
7Laboratory for Stem Cell Therapy, Faculty of Medicine, Tsukuba University, Japan
