Division of Animal Genetics

Genome engineering technologies achieve a "revolution" in life science and medical science. These techniques allow us to manipulate genes of interest for several purposes. Using those technologies, we have developed many useful strains in mice and rats. We are now focusing on generating "humanized animals" or "immunodeficient animals". These valuable animals can be used for xenotransplantation of human cells/tissues including human iPS cells. We are also developing therapeutic strategies such as cell therapy and gene therapy with genome editing tools.