| 1892: |
The Institute for Infectious Diseases, a private institute founded by Dr. Shibasaburo Kitasato. |
| 1899: |
The institute was transferred to the Ministry of Home Affairs. |
| 1906: |
The new Building of the institute was build at the Shiroganedai, Minatoku. |
| 1914: |
The institute was transferred to the Ministry of Education. |
| 1916: |
The institute was incorporated into the University of Tokyo. |
| 1947: |
The institute offered about half of its personnel, facilities, and space to establish a "National Institute of Health", under the control of the Ministry of Public Health and Welfere. |
| 1965: |
Laboratory Animal Research center |
| 1966: |
Amami Laboratory of Injurious Animals. |
| 1967: |
The name of the institute was changed to the Institute of Medical Science. Its primary aims and scope have been defined as basic and applied studies of diseases of medical importance. The Institute contained 18 research departments (Bacteriology, Bacterial Infection, lmmunology, Virology, Viral infection, Parasitology, Allergology, Reproductive and Developmental Biology, Oncology, Cancer Cell Research, Tumor Biology, Pathology, Fine Morphology, Molecular Neurobiology, Cell Chemistry, Molecular Biology, Internal Medicine, Surgery) and three facilities (Laboratory Animal Research Center, Amami Laboratory of Injurious Animals, Hospital) |
| 1968: |
Department of Tumor Virus Research. |
| 1969: |
Department of Molecular Oncology, Radiology (Hospital). |
| 1970: |
Department of Organ Transplantation. |
| 1970: |
Laboratory of Biological Products. |
| 1972: |
Internal Medicine and Surgery were renamed to, Infectious Diseases and Clinical Oncology respectively. |
| 1972: |
Laboratory of Culture Collection, Department of Transplantation Surgery (Hospital). |
| 1974: |
Department of Genetics. |
| 1974: |
Course of Tropical medicine has been held. |
| 1976: |
Department of Pathological Pharmacology. |
| 1976: |
Department of Laboratory Medicine (Hospital). |
| 1978: |
Medical Cyclotron Laboratory (Hospital). |
| 1979: |
Laboratory of Molecular Genetics. |
| 1980: |
Department of Biochemistry, Department of Infections Disease and Applied lmmunology (Hospital). |
| 1987: |
Department of Molecular and Developmental Biology. |
| 1989: |
Laboratory of Culture Collection was made to change to Laboratory of Molecular Medicine. |
| 1990: |
Department of Blood Transfusion (Hospital). |
| 1991: |
Human Genome Center (Laboratory of Genome Database), Surgical Center (Hospital). |
| 1992: |
The institute celebrated 100 anniversary of its establishment. Human Genome Center (Laboratory of Genome Structure Analysis) |
| 1993: |
Human Genome Center (Laboratory of DNA Information Analysis). |
| 1994: |
Medical Cyclotron Laboratory was abolished. Department of Clinical AIDS Research. |
| 1995: |
Donation Laboratories of Gene Regulation, Stem Cell Regulation (AMGEN) and Cell Processing (ASAHl CHEMICAL). |
| 1996: |
Laboratory of Molecular Medicine was remodeled into Human Genome center (Laboratory of Molecular Medicine and Laboratory of Genome Technology). Donation Laboratory of Hemopoietic Factors (CHUGAl). |
| 1997: |
Genome knowledge Discoverly System (HITACHI). Department of Advanced Medical Science (Hospital). |
| 1998: |
Molecular and Developmental Biology was renamed to the same DNA Biology and Embryo Engineering and Molecular Oncology were made to change to Center for Experimental Medicine Transplantation Surgery was renamed to Pediatric Hematology Oncology. |
| 1999: |
Welfare Building "Shirokane Hall" was renovated. Auditorium was renovated. Old Parasitology Building was renovated new "SNPs Building". |
| 2000: |
Old 19 departments were reorganized to 3 departments (Microbiology-lmmunology, Cancer Biology and Basic Medical Sciences). Clinical departments were reorganized to Advanced Clinical Research Center. Three divisions (Laboratory of Sequence Analysis, Laboratory of Functional Genomics, Laboratory of Functional in Silico) were added in Human Genome Center. Laboratory of Culture Collection was abrogated. Donation Division "Genetic Diagnosis (Otsuka)" was established. |
| 2001: |
The Research Hospital was reorganized. The Medical Science Museum was established. |
| 2003: |
The General Research Building and New Hospital Building were completed. |
| 2004: |
The University of Tokyo was reorganized as a national university corporation, according to the law (Heisei 15 law No.112). |
| 2005: |
The International Research Center for Infectious Diseases was established. |
| 2006: |
The IMSUT Research Center for Asian Infectious Diseases was established in Beijing. |
| 2007: |
The Frontier Research Initiative (for 5 years) was launched. |
| 2008: |
The Center for Stem Cell and Regenerative Medicine was established. The Todai Shirokane Himawari Day Nursery was established. |
| 2009: |
The Center for Experimental Medicine was reorganized into the Center for Experimental Medicine and Systems Biology. |
| 2011: |
The International Research and Development Center for Mucosal Vaccines was established. |
| 2014: |
The Center for Gene & Cell Therapy was established. |
| 2015: |
The Health Intelligence Center was established. |
| 2017: |
The institute celebrated 125th founding anniversary of its establishment and 50th reorganization anniversary. |
| 2018: |
The institute was officially recognized as an International Joint Usage/Research Center by the Minister of Education, Culture, Sports, Science and Technology. |
| 2020: |
The Health Intelligence Center was integrated into the Human Genome Center. |
| 2022: |
The International Research and Development Center for Mucosal Vaccines was reorganized into the International Vaccine Design Center. |
