| メッセージ | 研究内容 | メンバー | 研究業績 | メンバー募集 | アクセス | アルバム |
Y. Kawaguchi. Us3, a Multi-Functional Protein kinase Encoded by Herpes Simplex Virus 1:How does it Function In Vivo? Cornea (in press)
V. L. Sage, M. Jung, J. D. Alter, E. G. Wills, S. M. Johnston, Y. Kawaguchi, J. D. Baines and B. W. Banfield. The Herpes Simplex Virus Type 2 UL21 Protein is Essential for Virus Propagation. J. Virol. (in press)
2012年
M. Tanaka, A. Kato, Y. Satoh, T. Ide, K. Sagou, K. Kimura, H. Hasegawa and Y. Kawaguchi. (2012) Herpes Simplex Virus 1 VP22 Regulates Translocation of Multiple Viral and Cellular Proteins and Promotes Neurovirulence. J. Virol. 86: 5264-5277.
2011年
A. Kato, Z. Liu, A. Minowa, T. Imai, M. Tanaka, K. Sugimoto, Y. Nishiyama, J. Arii, and Y. Kawaguchi. (2011) Herpes Simplex Virus 1 Protein Kinase Us3 and Major Tegument Protein UL47 Reciprocally Regulate Their Subcellular Localization in Infected Cells. J. Virol. 85: 9599-9613.
T. Imai, J. Arii, A. Minowa, A. Kakimoto, N. Koyanagi, A. Kato and Y. Kawaguchi. (2011) Role of the Herpes Simplex Virus 1 Us3 Kinase Phosphorylation Site and Endocytosis Motifs in Envelope Glycoprotein B in Its Intracellular Transport and Neurovirulence. J. Virol. 85: 5003-5015.
P. Gee, Y. Ando, H. Kitayama, S. Yamamoto, Y. Kanemura, H. Ebina, Y. Kawaguchi and Y. Koyanagi. APOBEC1-mediated editing and attenuation of HSV-1 DNA implicates an antiviral role in neurons during encephalitis. J. Virol. (in press)
T. W. Wisner, K. Sugimoto, P. Howard, Y. Kawaguchi and D. C. Johnson. (2011) Anterograde transport of herpes simplex virus capsids in neurons by Separate and Married mechanisms. J. Virol. 85: 5919-5928.
2010年
J. Arii, H. Goto, T. Suenaga, M. Oyama, H. Kozuka-Hata, T. Imai, A. Minowa, H. Akashi, H. Arase, Y. Kawaoka and Y. Kawaguchi. (2010) Non-muscle myosin IIA is a functional entry receptor for herpes simplex virus 1. Nature 467: 859-862.
J. Arii, J. Wang, T. Morimoto, T. Suenaga, H. Akashi, H. Arase, and Y. Kawaguchi. (2010) A Single Amino Acid Substitution in Herpes simplex virus 1 Envelope Glycoprotein B at a Site Required for Binding to the Paired Immunoglobulin-like Type 2 Receptor a (PILRa) Abrogates PILRa-dependent Viral Entry and Reduces Pathogenesis. J. Virol. 84: 10773-10783.
K. Sagou, M. Uema and Y. Kawaguchi. (2010) Nucleolin is required for efficient nuclear egress of herpes simplex virus 1 nucleocapsids. J. Virol. 84: 2110-2121.
T. Imai, K. Sagou, J. Arii and Y. Kawaguchi. (2010) Effects of Phosphorylation of Herpes Simplex Virus 1 Envelope Glycoprotein B by Us3 Kinase In Vivo and In Vitro. J. Virol. 84: 153-162.
T. Suenaga, T. Satoh, P. Somboonthum, Y. Kawaguchi, Y. Mori, and H. Arase. (2010) Myelin-associated glycoprotein mediates membrane fusion and entry of neurotropic herpesviruses. Proc. Natl. Acad. Sci. USA 107: 866-871.
K. Gotoh, Y. Tanaka, A. Nishikimi, R. Nakamura, H. Yamada, N. Maeda, T. Ishikawa, K. Hoshino, T. Uruno, Q. Cao, S. Higashi, Y. Kawaguchi, M. Enjoji, R. Takayanagi, T. Kaisho, Y. Yoshikai, and Y. Fukui. (2010) Selective control of type I IFN induction by the Rac activator DOCK2 during TLR–mediated plasmacytoid dendritic cell activation. J. Exp. Med. 207: 721-730.
W. Azab, K. Tsujimura, K. Kato, J. Arii, T. Morimoto, Y. Kawaguchi, Y. Tohya, T. Matsumura and H. Akashi. (2010) Characterization of a thymidine kinase-deficient mutant of equine herpesvirus 4 and in vitro susceptibility of the virus to antiviral agents. Antiviral Res. 85: 389-395.
2009年
T. Morimoto, J. Arii, M. Tanaka, T. Sata, H. Akashi, M. Yamada, Y. Nishiyama, M. Uema and Y. Kawaguchi. (2009) Differences in the Regulatory and Functional Effects of the Us3 Protein Kinase Activities of Herpes Simplex Virus 1 and 2. J. Virol. 83: 11624-11634.
K. Sagou, T. Imai, H. Sagara, M. Uema, and Y. Kawaguchi. (2009) Regulation of the Catalytic Activity of Herpes Simplex Virus 1 Protein Kinase Us3 by Auto-Phosphorylation and Its Role in Pathogenesis. J. Virol. 83: 5773-5783.
J. Arii, M. Uema, T. Morimoto, H. Sagara, H. Akashi, E. Ono, H. Arase, and Y. Kawaguchi. (2009) Entry of herpes simplex virus 1 and other alphaherpesviruses via the paired immunoglobulin-like type 2 receptor a. J. Virol. 83: 4520-4527.
A. Kato, J. Arii, I. Shiratori, H. Akashi, H. Arase and Y. Kawaguchi. (2009) Herpes simplex virus 1 protein kinase Us3 phosphorylates viral envelope glycoprotein B and regulates its expression on the cell surface. J. Virol. 83: 250-261.
R. Asai, A. Kato and Y. Kawaguchi. (2009) Epstein-Barr Virus Protein Kinase BGLF4 Interacts with Viral Transactivator BZLF1 and Regulates Its Transactivation Activity. J. Gen. Virol. 90: 1575-1581.
J. Wang, F. Fan, T. Satoh, J. Arii, L. L. Lanier, P. G. Spear, Y. Kawaguchi, H. Arase. (2009) Binding of herpes simplex virus glycoprotein B (gB) to PILRa depends on specific sialylated O-linked glycans on gB. J. Virol. 83: 13042-13045.
T. W. Wisner, C. C. Wright, A. Kato, Y. Kawaguchi, F. Mou, J. D. Baines, R. J. Roller, and D. C. Johnson. (2009) Herpesvirus gB-induced fusion between the virion envelope and outer nuclear membrane during virus egress is regulated by the viral US3 kinase. J. Virol. 83: 3115-3126.
T. Morimoto, J. Arii, H. Akashi and Y. Kawaguchi. (2009) Identification of multiple sites in herpes simplex virus genomes suitable for insertion of foreign genes. Microbiol. Immunol. 53: 155-161.
H. Konno, T. Yamamoto, K. Yamazaki, J. Gohda, T. Akiyama, K. Semba, H. Goto, A. Kato, T. Yujiri, T. Imai, Y. Kawaguchi, B. Su, O. Takeuchi, S. Akira, Y. Tsunetsugu-Yokota, and J. Inoue. (2009) TRAF6 establishes innate immune responses by activating NF-kB and IRF7 upon sensing cytosolic viral RNA and DNA. PLoS ONE 4: e5674.
J. Arii, K. Kato, Y. Kawaguchi, Y. Tohya, H. Akashi. (2009) Analysis of herpesvirus host specificity determinants using herpesvirus genomes as bacterial artificial chromosomes. Microbiol. Immunol. 53: 433-441.
T. Nojima, T. Oshiro-Ideue, H. Nakanoya, H. Kawamura, T. Morimoto, Y. Kawaguchi, N. Kataoka,, M. Hagiwara. (2009) Herpesvirus protein ICP27 switches PML isoform by altering mRNA splicing. Nucleic Acids Res. 37: 6515-6527.
2008年
A. Kato, M. Tanaka, M. Yamamoto, R. Asai, T. Sata, Y. Nishiyama and Y. Kawaguchi. (2008) Identification of a physiological phosphorylation site of the Herpes simplex virus 1-encoded protein kinase Us3 which regulates its optimal catalytic activity in vitro and influences its function in infected cells. J. Virol. 82: 6172-6189.
K. Sugimoto, M. Uema, H. Sagara, M. Tanaka, T. Sata, Y. Hashimoto, and Y. Kawaguchi. (2008) Simultaneous Tracking of Capsid, Tegument and Envelope Protein Localization in Living Cells Infected with Triple Fluorescent Herpes Simplex Virus 1. J. Virol. 82: 5198-5211.
T. Satoh, J. Arii, T. Suenaga, J. Wang, A. Kogure, J. Uehori, N. Arase, I. Shiratori, S. Tanaka, Y. Kawaguchi, P. G. Spear, L. L. Lanier and H. Arase. (2008) PILRa is a herpes simplex-1 entry co-receptor that associates with glycoprotein B. Cell 132: 1-10.
Y. Orihara, H. Hamamoto, H. Kasuga, T. Shimada, Y. Kawaguchi and K. Sekimizu. (2008) Evaluation of therapeutic effects of antiviral agents using a silkworm baculovirus infection model. J. Gen. Virol. 89: 188-194.
Y. Ando, H. Kitayama, Y. Kawaguchi and Y. Koyanagi. Primary target cells of herpes simplex virus type 1 in the hippocampus. Microbes and Infection 10: 1514-1523.
Kamakura, M., Nawa, A., Ushijima, Y., Goshima, F., Kawaguchi, Y., Kikkawa, F., Nishiyama, Y. (2008) Microarray analysis of transcriptional responses to infection by herpes simplex virus types 1 and 2 and their US3-deficient mutants. Microbes and Infection 10: 405-413.
M. Tanaka, T. Sata and Y. Kawaguchi. (2008) The product of UL7 gene of herpes simplex virus type 1 interacts with a mitochondria protein, adenine nucleotide translocator 2. Virology J. 5: 125-137.
2007年
S. Iwahori, N. Shirata, Y. Kawaguchi, S. K. Weller, Y. Sato, A. Kudoh, S. Nakayama, H. Isomura, and T. Tsurumi. (2007) Enhanced Phosphorylation of Transcription Factor Sp1 dependent on Ataxia Telangiectasia-Mutated (ATM) in response to Herpes Simplex Virus Type I Infection. J. Virol. 81: 9653-9664.
R. Asai, T. Ohno, A. Kato and Y. Kawaguchi. (2007) Identification of proteins directly phosphorylated by UL13 protein kinase from herpes simplex virus 1. Microbes and Infection 9: 1434-1438.
T. Koshizuka, Y. Kawaguchi, N. Nozawa, I. Mori, and Y. Nishiyama. (2007) Herpes simplex virus protein UL11 but not UL51 is associated with lipid rafts. Virus Genes 35: 571-575.
Y. F. Chiu, C. P. Tung, Y. H. Lee, W. H. Wang, C. Li, J. Y. Hung, C. Y. Wang, Y. Kawaguchi, and S. T. Liu. (2007) A comprehensive library of mutations of Epstein Barr virus. J. Gen. Virol. 88: 2463-2472.
J. Garibal, E. Hollville, A. I. Bell, G. L. Kelly, B. Renouf, Y. Kawaguchi, A. B. Rickinson, and J. Wiels. (2007) Truncated form of the Epstein-Barr virus protein EBNA-LP protects against caspase-dependent apoptosis by inhibiting protein phosphatase 2A. J. Virol. 81: 7598-7607.2006年
A. Kato, M. Yamamoto, T. Ohno, M. Tanaka, T. Sata, Y. Nishiyama, and Y. Kawaguchi. (2006) Herpes Simplex Virus 1-Encoded Protein Kinase UL13 Phosphorylates the Viral Us3 Protein Kinase and Regulates nuclear Localization of Viral Envelopment Factors UL34 and UL31. J. Virol. 80: 1476-1486.
R. Asai, A. Kato, K. Kato, M. Kanamori-Koyama, K. Sugimoto, T. Sairenji, Y. Nishiyama, and Y. Kawaguchi. (2006) Epstein-Barr Virus Protein Kinase BGLF4 Is a Virion Tegument Protein That Dissociate From Virions in a Phosphorylation Dependent Process and Phosphorylates the Viral Imediate-Early Protein BZLF1. J. Virol. 80: 5125-5134.
A. Kudoh, T. Daikoku, Y. Ishimi, Y. Kawaguchi, N. Shirata, S. Iwahori, H. Isomura, and T. Tsurumi. (2006) Phosphorylation of MCM4 at Sites Inactivating DNA Helicase Activity of the MCM4-6-7 Complex during Epstein-Barr Virus Productive Replication. J.Virol. 80: 10064-10072.
J. Arii, O. Hushur, K. Kato, Y. Kawaguchi, Y. Tohya and H. Akashi. Construction of an infectious clone of canine herpesvirus genome as a bacterial artificial chromosome. (2006) Microbes and Infection 8: 1054-1063.
2005年
A. Kato, M. Yamamoto, T. Ohno, H. Kodaira, Y. Nishiyama, and Y. Kawaguchi. (2005) Identification of proteins phosphorylated directly by the Us3 protein kinase encoded by herpes simplex virus 1. J. Virol. 79: 9325-9331.
M. Tanaka, Y. Nishiyama, T. Sata, and Y. Kawaguchi. (2005) The role of protein kinase activity expressed by the UL13 gene of herpes simplex virus 1: The activity is not essential for optimal expression of ICP0 and UL41. Virology 341: 301-312.
N. Nozawa, Y. Kawaguchi, M. Tanaka, A. Kato, A. Kato, H. Kimura, and Y. Nishiyama. (2005) Herpes Simplex Virus Type 1 UL51 Protein Is Involved in Maturation and Egress of Virus Particles. J. Virol. 79: 6947-6956.
T. Koshizuka, Y. Kawaguchi, and Y. Nishiyama. (2005) The HSV-2 membrane protein UL56 associates with the kinesin motor protein KIF1A. J. Gen. Virol. 86: 527-533.
A. Matsuzaki, Y. Yamauchi, A. Kato, F. Goshima, Y. Kawaguchi, T. Yoshikawa, and Y. Nishiyama. (2005) The Us3 protein kinase of herpes simplex virus type 2 is required for the stability of the UL46-encoded tegument protein and its association with virus particles. J. Gen. Virol. 86: 1979-1985.
F. Shaku, G. Matsuda, R. Furuya, C. Kamagata, M. Igarashi, M. Tanaka, M. Kanamori, Y. Nishiyama, N. Yamamoto, and Y. Kawaguchi (2005) Development of a Monoclonal Antibody against Epstein-Barr Virus Nuclear Antigen Leader Protein (EBNA-LP) that Can Detect EBNA-LP Expressed in P3HR1 Cells. Microbiol. Immunol. 49: 477-483.
2004年
M. Kanamori, S. Watanabe, R. Honma, M. Kuroda, S. Imai, K. Takada, N. Yamamoto, Y. Nishiyama, and Y. Kawaguchi. (2004) Epstein-Barr Virus Nuclear Antigen Leader Protein Induces Expression of Thymus and Activation-Regulated Chemokine in B Cells. J. Virol. 78: 3984-3993.
M. Tanaka, H. Kodaira, Y. Nishiyama, T. Sata and Y. Kawaguchi. (2004) Construction of recombinant herpes simplex virus type 1 expressing green fluorescence protein without loss of any viral genes. Microbes and Infection 6: 485-493.
L. Liang, M. Tanaka, Y. Kawaguchi, and J. D. Baines. (2004) Cell lines that support replication of a novel herpes simplex 1 UL31 deletion mutant can properly target UL34 protein to the nuclear rim in the absence of UL31. Virology 329: 68-76.
N. Nozawa, Y. Yamauchi, K. Ohtsuka, Y. Kawaguchi and Y. Nishiyama. (2004) Formation of aggresome-like structures in herpes simplex virus type 2-infected cells and a potential role in virus assembly. Exp. Cell Res. 299: 486-497.
2003年
Y. Kawaguchi, K. Kato, M. Tanaka, M. Kanamori, Y. Nishiyama, and Y. Yamanashi. (2003) Conserved Protein Kinases Encoded by Herpesviruses and a Cellular Protein Kinase Cdc2 Target the Same Phosphorylation Site In Eukaryotic Elongation Factor 1d. J. Virol. 77: 2359-2368.
M. Tanaka, H. Kagawa, Y. Yamanashi, T. Sata and Y. Kawaguchi. (2003) Construction of an Excisable Bacterial Artificial Chromosome Containing a Full-Length Infectious Clone of Herpes Simplex Virus Type 1: Viruses Reconstituted from the Clone Exhibits Wild-Type Properties In Vitro and In Vivo. J. Virol. 77: 1382-1391.
Y. Kawaguchi and K. Kato. (2003) Protein kinases conserved in herpesviruses potentially share a function mimicking the cellular protein kinase cdc2. Rev. Med. Virol. 13: 331-340.
K. Kato, A. Yokoyama, Y. Tohya, H. Akashi, Y. Nishiyama, and Y. Kawaguchi. (2003) Identification of protein kinases responsible for phosphorylation of Epstein-Barr virus nuclear antigen leader protein at serine 35 that regulates its coactivator function. J. Gen. Virol. 84: 3381-3392.
M. Igarashi, Y. Kawaguchi*, K. Hirai, and F. Mizuno. (2003) Physical interaction of Epstein-Barr Virus (EBV) nuclear antigen leader protein (EBNA-LP) with human estrogen-related receptor 1 (hERR1): hERR1 interacts with a conserved domain of EBNA-LP that is critical for EBV-induced B-cell immortalization. J. Gen. Virol. 84: 319-327.
*Corresponding author
G. Matsuda, K. Nakajima, Y. Kawaguchi*, Y. Yamanashi and K. Hirai. (2003) Epstein-Barr virus (EBV) nuclear antigen leader protein (EBNA-LP) forms complexes with a cellular anti-apoptosis protein bcl-2 or its EBV counterpart BHRF1 through HS1-associated protein X-1. Microbiol. Immunol. 47: 91-99.
*Corresponding author
2002年
M. Tanaka, A. Yokoyama, M. Igarashi, G. Matsuda, K. Kato, M. Kanamori, H. Yamada, K. Hirai, Y. Kawaguchi* and Yuji Yamanashi. (2002) The Conserved region CR2 of Epstein-Barr Virus Nuclear Antigen Leader Protein Is a Multifunctional Domain that mediates Self-Association As Well As Nuclear Localization and Nuclear Matrix Association. J. Virol. 76: 1025-1032.
*Corresponding author
K. Kato, Y. Izumiya, Y. Tohya, E. Takahashi, K. Hirai, and Y. Kawaguchi. (2002) Characterization of the regulatory function of the Marek’s disease virus serotype 1 ICP22 homologue. Vet. Microbiol. 85: 305-313.
R. Katsu, H. Onogi, K. Wada, Y. Kawaguchi, and M. Hagiwara. (2002) Novel SR-rich-related protein Clasp specifically interacts with inactivated Clk4 and induces the exon inclusion of Clk. J. Biol. Chem. 277: 44220-44228.
2001年
Y. Kawaguchi, M. Tanaka, A. Yokoyama, G. Matsuda, K. Kato, H. Kagawa, K. Hirai, and B. Roizman. (2001) Herpes Simplex Virus Type 1 a Regulatory Protein ICP0 Functionally Interacts with a Cellular Transcription Factor BMAL1. Proc. Natl. Acad. Sci. USA 98: 1877-1882 .
Yokoyama, M. Tanaka, G. Matsuda, K. Kato, M. Kanamori, H. Kawasaki, H. Hirano, I. Kitabayashi, M. Ohki, K. Hirai, and Y. Kawaguchi. (2001) Identification of major phosphorylation sites of Epstein-Barr virus nuclear antigen leader protein (EBNA-LP): The function of EBNA-LP to induce latent membrane protein 1 co-operatively with EBNA-2 is regulated by phosphorylation. J. Virol. 75: 5119-5128.
Yokoyama, Y. Kawaguchi*, I. Kitabayashi, M. Ohki, and K. Hirai. (2001) The Conserved Domain CR2 of Epstein-Barr Virus Nuclear Antigen Leader Protein is Responsible Not Only for Nuclear Matrix Association But Also for Nuclear Localization. Virology 279: 401-413.
*Corresponding author
K. Kato, Y. Kawaguchi*, M. Tanaka, Mie Igarashi, Akihiko Yokoyama, Go Matsuda, Mikiko Kanamori, Kaori Nakajima, Yorihiro Nishimura, Masayuki Shimojima, Hang T. T. Phung, Eiji Takahashi, and Kanji Hirai. (2001) Epstein-Barr Virus Encoded-Protein Kinase BGLF Mediates Hyper-phosphorylation of Cellular Elongation Factor1d (EF-1d): EF-1d Is Universally Modified by Conserved Protein Kinases of Herpesviruses. J. Gen. Virol. 82: 1457-1463.
*Corresponding author
2000年
Y. Kawaguchi, K. Nakajima, M. Igarashi, T. Morita, M. Tanaka, M. Suzuki, A. Yokoyama, G. Matsuda, K. Kato, M. Kanamori, and K. Hirai. (2000) Interaction of Epstein-Barr Virus Nulear Antigen Leader Protein (EBNA-LP) with HS1-associated protein X-1: Implication of cytoplasmic function of EBNA-LP. J. Virol. 74: 10104-10111.
K. Sonoda, M. Sakaguchi, H. Okamura, K. Yokogawa, E. Tokunaga, S. Tokiyoshi, Y. Kawaguchi, and K. Hirai. (2000). Development of effective polyvalent vaccine against both Marek's and Newcastle diseases based on recombinant Marek's disease virus type 1 in commercial chickens with maternal antibodies. J. Virol. 74: 3217-3226.
1999年以前
Y. Kawaguchi, T. Matsumuta, B. Roizman, and K. Hirai. (1999) The cellular elongation factor 1d is modified in cells infected with representative alpha-, beta, or gamma herpesviruses. J. Virol. 73: 4456-4460.
C. Van Sant, Y. Kawaguchi, and B. Roizman. (1999) A single amino acid substitution in the cyclin D binding domain of the infected cell protein No.0 abrogates the neuroinvasiveness of herpes simplex virus without affecting its ability to replicate. Proc. Natl. Acad. Sci. USA 96: 8184-8189.
Y. Kawaguchi, C. Van Sant, and B. Roizman. Eukaryotic elongation factor 1d is hyperphosphorylated by the protein kinase encoded by the UL13 gene of herpes simplex virus 1. (1998) J. Virol. 72: 1731-1736.
Y. Ikeda, Y. Inoshima, Y. Kawaguchi, K. Maeda, M. Kohmoto, T. Miyazawa, C. Kai, and T. Mikami. (1998) Protein-binding properties of the putative AP-1 and ATF sequence in the feline immunodeficiency virus long terminal repeat. J. Gen. Virol. 78: 95-99.
Y. Kawaguchi, R. Bruni, and B. Roizman. (1997) Interaction of herpes simplex virus 1 a regulatory protein ICP0 with elogation factor 1d: ICP0 affects translational machinery. J. Virol. 71: 1019-1024.
Y. Kawaguchi, C. Van Sant, and B. Roizman. (1997) Herpes simplex virus-1 a regulatory protein ICP0 interacts with and stabilizes cell cycle regulator cyclin D3. J. Virol. 71: 7328-7336.
K. Hirasawa, H. S. Jun, K. Maeda, Y. Kawaguchi, S. Itagaki, T. Mikami, H. S. Baek, K. Doi, and J. W. Yoon. (1997) Possible role of macrophage-derived soluble mediators in the pathogenesis of encephalomyocarditis virus-induced diabetes in mice. J. Virol. 71: 4024-4031.
Y. Tohya, N. Yokoyama, K. Maeda, Y. Kawaguchi and T. Mikami. (1997) Mapping of antigenic sites involved in neutralization on the capsid protein of feline calicivirus. J. Gen. Virol. 78: 303-305.
Y. Kawaguchi, K. Maeda, N. Yokoyama, K. Fujita, M. Ono, Y. Tohya, and T. Mikami. (1997) Expression of feline herpesvirus type 1 ICP4 gene is controlled by two alternative promoters. Arch Virol. 142: 239-253.
Y. Inoshima, M. Kohmoto, Y. Ikeda, H. Yamada, Y. Kawaguchi, K. Tomonaga, T. Miyazawa, T. Umemura, C. Kai and T. Mikami. (1996) Roles of the auxiliary genes and AP-1 binding sites in the long terminal repeat of feline immunodeficiency virus in early stage of infection in cats. J. Virol. 70: 8518-8526.
Y. Ikeda, K. Tomonaga, Y. Kawaguchi, M. Kohmoto, Y. Inoshima, Y. Tohya, C. Kai, T. Miyazawa, and T. Mikami. (1996) Cell-free feline immunodeficiency virus can infect a human cell line (MOLT-4 cells) but is a state of an absolute latency in the cells. J. Gen. Virol. 77: 1623-1630.
M. R. Pecoraro, K. Tomonaga, T. Miyazawa, Y. Kawaguchi, S. Sugita, Y. Tohya, C. Kai, M. E. Etcheverrigaray, and T. Mikami. (1996) Genetic diversity of Argentine isolates of feline immunodeficiency virus. J. Gen. Virol. 77: 2031-2035.
M. R. Pecoraro, Y. Kawaguchi, K. Maeda, Y. Inoshima, C. Kai, and T. Mikami. (1996) Molocular cloning of the feline CD8b chain. Immunology 89: 84-88.
N. Yokoyama, K. Maeda, Y. Tohya, 47. Y. Kawaguchi, K. Fujita, and T. Mikami. (1996) Recombinant feline herpesvirus type 1 expressing immunogenic proteins inducible vieus neutralizing antibody against feline calicivirus in cats. Vaccine. 14: 1657-1663.
Y. Kawaguchi, K. Maeda, M. Ono, N. Yokoyama, K. Fujita, Y. Tohya, C. Kai, and T. Mikami. (1996) Characterization of the feline herpesvirus type 1 immediate-early gene expression. J. Vet. Med. Sci. 58: 715-721.
Y. Kawaguchi, K. Tomonaga, K. Maeda, M. Ono, T. Miyazawa, M. Kohmoto, Y. Tohya, and T. Mikami. (1995) The C/EBP site in the feline immunodeficiency virus (FIV) long terminal repeat (LTR) is necessary for its efficient replication and is also involved in the inhibition of FIV LTR-directed gene expression by pseudorabies virus ICP4. Virology 208: 492-499.
K. Maeda, Y. Kawaguchi, M. Ono, T. Tajima and T. Mikami. (1995) Restriction endonuclease analysis of field isolates of feline herpes virus type 1 and identification of the heterogenous regions. J. Clin. Microbiol. 33: 217-221.
Y. Kawaguchi, K. Maeda, M. R. Pecoraro, Y. Inoshima, H.-K. Jang, M. Kohmoto, K. Iwatsuki, Y. Ikeda, M. Shimojima, Y. Tohya, C. Kai and T. Mikami. (1995) Feline herpesvirus type 1 ICP4 down-regulate feline immunodeficiency virus long terminal repeat (LTR)-directed gene expression via the C/EBP site in the LTR. J. Vet. Med. Sci. 57: 1129-1131.
Y. Kawaguchi and T. Mikami. (1995) Molecular interactions between retrocviruses and herpesviruses. J. Vet. Med. Sci. 57: 801-811.
Y. Kawaguchi, K. Maeda, T. Miyazawa, M. Ono, C. Kai, and T. Mikami. (1994) Nucleotide sequence and characterization of the feline herpesvirus type 1 immediate early gene. Virology 204: 430-435.
Y. Kawaguchi, K. Maeda, T. Miyazawa, M. Ono, K. Tsubota, K. Tomonaga, and T. Mikami (1994) Inhibition of feline immunodeficiency virus gene expression and replication by alphaherpesvirus ICP4 homologues. J. Gen. Virol. 75: 2783-2787.
M. R. Pecoraro, Y. Kawaguchi, T. Miyazawa, J. Norimine, K. Maeda, T. Toyosaki, Y. Tohya, C. Kai, and T. Mikami. (1994) Isolation, sequence and expression of a cDNA encoding the a-chain of the feline CD8. Immunology 81: 127-131.
M. Ono, Y. Kawaguchi, K. Maeda, N. Kamiya, Y. Tohya, C. Kai, and T. Mikami. (1994) Nucleotide sequence analysis of Marek's didease virus (MDV) serotype 2 homolog of MDV serotype 1 pp38, an antigen associated with transformed cells. Virology 201: 142-146.
K. Maeda, Y. Kawaguchi, M. Ono, Y. Inoshima, T. Miyazawa, Y. Tohya, C. Kai, and T. Mikami. (1994) A gD homologous gene of feline herpesvirus type 1 encodes a hemagglutinin (gp60). Virology 202: 1034-1038.
M. Kohmoto, T. Miyazawa, K. Tomonaga, Y. Kawaguchi, T. Mori, Y. Tohya, C. Kai, and T. Mikami (1994) Comparison of biological properties of feline immunodeficiency virus isolates using recombinant chimera viruses. J. Gen. Virol. 75: 1935-1942.
Y. Kawaguchi, Y. Tohya, T. Horimoto, K. Maeda, T. Miyazawa, and T. Mikami. (1994) Carrier-state infection of feline T-lymphoblastoid cells with feline calicivirus. Vet. Micobiol. 40: 379-386.
T. Miyazawa, M. Kohmoto, Y. Kawaguchi, K. Tomonaga, T. Toyosaki, K. Ikuta, A. Adachi, and T. Mikami. (1993) The AP-1 binding iste in the feline immunodeficiency virus long terminal repeat is not required for virus replication in feline T lymphocytes. J. Gen. Virol. 74: 1573-1580.
Y. Kawaguchi, J. Norimine, T. Miyazawa, C. Kai, and T. Mikami. (1992) Sequences within the feline immunodeficiency virus long terminal repeat that regulate gene expression and respond to activation by feline herpesvirus type 1. Virology 190: 465-468.
T. Miyazawa, Y. Kawaguchi, M. Kohmoto, J. Sakuragi, A. Adachi, M. Fukasawa, and T. Mikami. (1992) Production of feline immunodeficiency virus in feline and non-feline non-lymphoid cell lines by transfection of an infectious molecular clone. J. Gen. Virol. 73: 11543-1546.
K. Tomonaga, J. Norimine, Y. Shin, M. Fukasawa, T. Miyazawa, A. Adachi, T. Toyosaki, Y. Kawaguchi, C. Kai, and T. Mikami. (1992) Identification of a feline immunodeficiency virus gene which is essential for cell-free virus infectivity. J. Virol. 66: 6181-6185.
J. Norimine, T. Miyazawa, Y. Kawaguchi, Y. Tohya, C. Kai, and T. Mikami. (1992) A cDNA encoding feline CD4 has a unique repeat sequence downstream of the V-like region. Immunology 75: 74-79.
Y. Kawaguchi, K. Maeda, Y. Tohya, T. Furuya, T. Miyazawa, T. Horimoto, J. Norimine, C. Kai, and T. Mikami. (1992) Replicative difference in early-passage feline brain cells among feline immunodeficiency virus isolates. Arch. Virol. 125: 347-354.
Y. Kawaguchi, T. Miyazawa, T. Horimoto, S. Itagaki, M. Fukasawa, E. Takahashi, and T. Mikami. (1991) Activation of feline immunodeficiency virus long terminal repeat by feline herpesvirus type 1. Virology 184: 449-454.
Y. Kawaguchi, T. Miyazawa, Y. Tohya, E. Takahashi, and T. Mikami. (1990) Quantification of feline immunodeficiency virus in a newly established feline T-lymphoblastoid cell line (MYA-1 cells). Arch. Virol. 111: 269-273.
川口 寧 (2012) ヘルペスウイルスによるリン酸化を介した宿主機能制御 増刊「感染・共生・生体防御システム」 実験医学 30: 3202-3208.
川口 寧 (2012) マウスでもヒトの病態が再現できるウイルス〜単純ヘルペスウイルス〜
JSI Newsletter 21 (1): 13.
川口 寧 (2012) ヘルペスウイルスによる病態を科学し、制御する 化学療法の領域 28: 666-671.
川口 寧 (2012) ヘルペスウイルスの感染機構 生化学 84: 343-351.
加藤哲久、川口 寧 (2012) ヘルペスウイルスの新規薬剤標的 日本臨床 70: 699-694.
川口 寧 (2011) ヘルペスウイルスの新規受容体 Medical Science Digest 37: 390-392.
川口 寧 (2011) ヘルペスウイルス感染症 pp187-193 獣医微生物学第 ３版 見上 彪 監修 文英堂出版
川口 寧 (2011) 非筋肉ミオシンIIAは単純ヘルペスウイルスの機能的受容体である 細胞工学 30: 182-183.
川口 寧 (2011) ヘルペスウイルスの新規受容体を発見 科研費NEWS 2010年度 Vol. 4: 15
川口 寧 (2010) 単純ヘルペスウイルス ウイルス 60: 187-196.
川口 寧 (2010) ウイルスってみえないから敷居が高いんだよね1? JSI Newsletter 18 (2): 22.
川口 寧 (2010) 単純ヘルペスウイルスの潜伏感染 化学療法の領域 26: 1180-1187.
川口 寧 (2009) 生きた細胞におけるヘルペスウイルスのリアルタイムイメージング Virus Report 6: 94-105.
川口 寧 (2008) 生きた細胞におけるウイルスの可視化 ウイルス 58: 117-124.
川口 寧 (2008) ウイルス学における機能ゲノミクス ゲノム医学 8: 217-221.
川口 寧 (2008) ヘルペス群ウイルスの共通と多様性 pp77-82 EBウイルス改訂第2版 高田賢蔵監修 診断と治療社
川口 寧、杉本 研 (2007) 生きた感染細胞におけるウイルス粒子およびその成熟課程の可視化 感染・炎症・免疫 37; 311-319.
川口 寧 (2007) 生きた細胞内のウイルスを見る 未来材料 7 (12) : 2-5.
川口 寧 (2007) ヘルペスウイルスがコードするプロテインキナーゼーさまざまなウイルス感染現象を制御するウイルス特異酵素の役割 増刊「ウイルス研究の現在と展望」 蛋白質核酸酵素 52: 1175-1180.
川口 寧 (2006) 単純ヘルペスウイルスとユビキチン-プロテアソーム系 日本臨床 64, Suppl. 3: 140-144.
川口 寧 (2006) ヘルペスウイルスの増殖機構 日本臨床 64, Suppl. 3: 154-158.
川口 寧、西山幸廣 (2005) ヘルペスウイルスの増殖機構とヘルペスウイルスベクターの開発 Virus Report 1: 35-43
川口 寧 (2005) すべてのヘルペスウイルスで保存されているプロテインキナーゼの機能—宿主細胞プロテインキナーゼcdc2の模倣 細胞工学 24; 122-126.
川口 寧、田中道子 (2004) BACシステム：大腸菌遺伝学とウイルス学が融合した新しいヘルペスウイルス遺伝子改変法 ウイルス 54: 255-264.
川口 寧 (2004) Epstein-Barrウイルス潜伏関連因子によるB細胞の不死化機構 Journal of Veterinary Medicine 57: 588-590.
川口 寧 (2004) 単純ヘルペスウイルスを用いた’human therapy’ Mebio 21: 24-33.
西山幸廣、川口 寧 (2003) ヘルペスウイルスの医学的利用—遺伝子治療と癌治療への応用— ウイルス 53: 155-162.
川口 寧 (2003) ヘルペスウイルス感染症 pp203-208 獣医微生物学第２版 見上 彪 監修 文英堂出版
川口 寧 (2002) ヘルペスウイルス遺伝子発現制御因子の機能発現機構の解明 ウイルス 52: 207-216.
川口 寧 (2002) 新しいヘルペスウイルスベクターの開発 上原記念生命科学財団研究報告集 16: 328-331.
川口 寧 (2000) アルファヘルペスウイルス遺伝子関連事項：遺伝子発現制御機構 日本臨床 58: 779-786.
川口 寧 (1999) 酵母を用いたTwo-hybrid systemのウイルス学分野での利用法 ウイルス 49: 19-26.
田中道子、川口 寧、平井莞二 (1999) EBウイルス遺伝子の構造と機能 臨床と微生物 26: 461-469.
川口 寧 (1999) 単純ヘルペスウイルス感染における転写制御因子 増刊「転写研究1999」 実験医学 17: 405-411.
川口 寧 (1997) 単純ヘルペスウイルスの遺伝子発現制御因子-ウイルス制御因子の驚くべき多機能性と宿主因子との相互作用 増刊「ウイルス最前線」 実験医学 15: 2329-2335.