Department of AIDS Vaccine Development

We are working on Microbiology and Immunology to elucidate the immune mechanism for viral control in vivo. For development of an effective AIDS vaccine, we established an AIDS model using groups of rhesus macaques sharing individual MHC-I haplotypes and are studying virus-host immune interaction. We are developing vaccines using Sendai virus vectors eliciting antibody and/or cytotoxic T lymphocyte responses. We are also studying how HIVs evolve in human populations.