The Institute of Medical Science, The University Of Tokyo

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Department of Cancer Biology

Chair:Yuji Yamanashi Organization/Researchers

Formation and developement of cancer are multi-step that involves alteration of structure adn function of various genes that are relevant to cell growth, differentiation, and to cell-cell communication, the genes include oncogenes, tumor suppressor genes, and their related genes. In the Department of Cancer Biology, we try to establish molecular mechaminsms of tumor formation and development basing on the function of these gene products.
Our goal is to understand
(1) how the cell growth and differentiation are regulated,
(2) molecular basis of angiogenesis,
(3) molecular meachanisms of invasion and metastasis of cancer,
(4) mechanisms of malignant transformation by tumor viruses,
and their pathogenic mechanisms of human cancer.

On going researches are as follows:

  1. Structure, expression, and function of cancer related genes including oncogenes and tumor suppressor genes
  2. Studies on signal transduction and gene expression involved in cell growth and differentiation
  3. Studies on inositol-phospholipid signaling
  4. Studies on cell-cell interaction, cell motility, and cytoskelton
  5. Molecular mechanisms of tumor angiogenesis, cancer cell invasion, and metastasis
  6. Molecular pathogenesis of malignant lymphomas, other solid tumors, and retrovirus-associated neoplasms

Division of Cellular and Molecular Biology

Head:Jun-ichiro Inoue | General Research Building 1F


 

Professor

Jun-ichiro Inoue

+81-3-5449-5275

Associate Professor Taishin Akiyama

+81-3-5449-5276

Assistant Professor Yuu Taguchi

+81-3-5449-5277

Assistant Professor Yuri Shibata

+81-3-5449-5278

Division of Cellular and Molecular Biology Website

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Division of Molecular Pathology

Head:Yoshinori Murakami


 

Professor

Yoshinori Murakami

Visiting Professor Naohiko Koshikawa  
Visiting Associate Professor Daisuke Matsubara  
Assistant Professor Takeharu Sakamoto  
Assistant Professor Takeshi Ito  

Division of Molecular Pathology Website

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Division of Genetics

Head:Yuji Yamanashi | Third Building 3F


 

Professor

Yuji Yamanashi

+81-3-6409-2115

Assistant Professor Tohru Tezuka

+81-3-6409-2118

Assistant Professor Ryo Ueta

+81-3-6409-2118

Assistant Professor Sumimasa Arimura

+81-3-6409-2117

Division of Genetics Website

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Division of Cancer Cell Biology

Head:Makoto Nakanishi


 

Professor

Makoto Nakanishi

+81-3-5449-5341

Division of Cancer Cell Biology Website

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