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Department of Cancer Biology
Chair:Yuji Yamanashi | Organization/Researchers |
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- Division of Molecular Pathology
- Division of Cellular and Molecular Biology
- Division of Genetics
- Division of Cancer Cell Biology
Formation and developement of cancer are multi-step that involves alteration of structure adn function of various genes that are relevant to cell growth, differentiation, and to cell-cell communication, the genes include oncogenes, tumor suppressor genes, and their related genes. In the Department of Cancer Biology, we try to establish molecular mechaminsms of tumor formation and development basing on the function of these gene products.
Our goal is to understand
(1) how the cell growth and differentiation are regulated,
(2) molecular basis of angiogenesis,
(3) molecular meachanisms of invasion and metastasis of cancer,
(4) mechanisms of malignant transformation by tumor viruses,
and their pathogenic mechanisms of human cancer.
On going researches are as follows:
- Structure, expression, and function of cancer related genes including oncogenes and tumor suppressor genes
- Studies on signal transduction and gene expression involved in cell growth and differentiation
- Studies on inositol-phospholipid signaling
- Studies on cell-cell interaction, cell motility, and cytoskelton
- Molecular mechanisms of tumor angiogenesis, cancer cell invasion, and metastasis
- Molecular pathogenesis of malignant lymphomas, other solid tumors, and retrovirus-associated neoplasms
Division of Molecular Pathology
Head:Yoshinori Murakami | Fourth Building 4F
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Professor Yoshinori Murakami |
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Project Professor | Takayuki Morisaki | |
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Visiting Professor | Naohiko Koshikawa | |
Visiting Associate Professor | Daisuke Matsubara | |
Assistant Professor | Takeshi Ito |
Division of Cellular and Molecular Biology
Head:Jun-ichiro Inoue | General Research Building 1F
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Professor Jun-ichiro Inoue +81-3-5449-5275 |
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Associate Professor | Takeharu Sakamoto | |
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Assistant Professor | Yuu Taguchi | +81-3-5449-5277 |
Assistant Professor | Mizuki Yamamoto | +81-3-5449-5521 |
Division of Genetics
Head:Yuji Yamanashi | Third Building 3F
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Professor Yuji Yamanashi +81-3-6409-2115 |
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Assistant Professor | Ryo Ueta | +81-3-6409-2118 |
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Assistant Professor | Akane Yamauchi |
Division of Genetics Website
Division of Cancer Cell Biology
Head:Makoto Nakanishi | Fourth Building 2F
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Professor Makoto Nakanishi +81-3-5449-5341 |
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Associate Professor | Atsuya Nishiyama | |
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Assistant Professor | Yoshikazu Johmura |
Division of Cancer Cell Biology Website