Division of Genetics

The major interest of this division is in molecular signals that regulate a variety of cellular activities. Our aim is to address how dysregulated cellular signals give rise to neoplastic, developmental, immune or neuromuscular disorders. Our goal is to understand the molecular bases of tumorigenesis and the development of other intractable diseases as a path toward uncovering therapeutic targets. Currently, we are investigating regulatory mechanisms in protein-tyrosine kinase-mediated signaling pathways, their pathophysiological roles and the potential for therapeutic intervention.