PUBLICATIONS (2000-2003)

Harada, Y., Miyatake, S., Arai, K., Watanabe, S., (2000) Cyclic AMP inhibits the activity of c-Jun N-terminal kinase 2 (JNK2) but not JNK1 and ERK2, in human helper T lymphocytes. Biochem. Biophys. Res. Comm. 266, 129-134

Liu, R., Liu, C.-B., Mohi, M.G., Arai, K., Watanabe, S. (2000) Signals for prevention of g irradiation-induced apoptosis by hGM-CSF. Oncogene 19, 571-579

Dahl, M. E., Arai, K., Watanabe, S. (2000) Association of Lyn tyrosine kinase to the GM-CSF and IL-3 receptor common bc subunit and role of Src tyrosie kinases in DNA synthesis and anti-apoptosis., Genes to Cells 5, 143-153

Liu, R., Arai, K., Watanabe, S. (2000) Antiapoptotic activity of the hGM-CSF receptor. J. Allergy Clin. Immunol. 106, 10-18

Watanabe, S., Aoki, Y., Nishijima, I., Xu, M.-J., Arai, K. (2000) Analysis of signals and functions of the chimeric hGM-CSF receptor in BA/F3 cells and transgenic mice. J. Immunol. 164, 3653-3644

Sato, T., Maekawa, T., Watanabe, S., Tsuji, K., Nakahata, T., (2000) Erythroid Progenitors Differentiate and Mature in Response to Endogenous Erythropoietin, J. Clinical Invest. 106, 263-270.

Okubo, T., Yanai, N., Watanabe, S., Arai K.-I. and Obinata M. (2000) Effect of human granulocyte-macrophage colony stimulating factor (hGM-CSF) on lymphoid and myeloid differentiation of sorted hematopoietic stem cells from hGM-CSF receptor gene transgenic mice. J. Biochem. 127, 591-596

Sakurai, Y., Arai, K., Watanabe, S. (2000) In vitro analysis of mechanism of STAT5 activation by granulocyte-macrophage colony-stimulating factor. Genes to Cells. 5, 937-947

Watanabe, S., Zeng, R., Aoki, Y., Itoh, T., Arai, K. (2001) Initiation of polyoma virus origin dependent DNA replication through STAT5 activation by human granulocyte-macrophage colony-stimulating factor (GM-CSF). Blood 97, 1266-1273

Takeda, M, Dohmae, N., Takio, K., Arai, K., Watanabe, S., (2001) Mad2 interacts with conserved box1/2 region of hGM-CSF receptor common bc in cell cycle dependent manner. J. Biol. Chem. 276, 41803-41809

Hisakawa, H., Sugiyama, D., Nishijima, I., Wu, H., Nakao, K., Watanabe, S., Katsuki, M., Asano, S., Arai, K., Nakahata, T., Tsuji, K. (2001) Human granulocyte-macrophage colony-stimulating factor (hGM-CSF) stimulates primitive and definitive erythropoiesis in mouse embryo expressing hGM-CSF receptors but not erythropoietin receptors. Blood, 98, 3618-3625

Nakamura, T., Ouchida, R., Kodama, T., Kawashima, T., Makino, Y., Yoshikawa, N., Watanabe, S., Morimoto, C., Kitamura, T., Tanaka, H. (2002) Cytokine receptor common beta subunit-mediated STAT5 activation confers NF-kB activation through IkB-independent mechanism in murine proB cell line Ba/F3 cells. J. Biol. Chem., 277, 6254-6265

Zeng, R., Aoki, Y., Yoshida, M., Arai, K., Watanabe, S. (2002) Stat5b shuttles between cytoplasm and nucleus in cytokine-dependent and -independent manner. J. Immunol. 168, 4567-4575

Watanabe, S., Murakami, T., Nakamura, T., Morimoto, C., Arai, K. (2002) Human GM-CSF induces HIV-1 LTR by multiple signalling pathways. Biochimie 84, 633-642

Akagawa, E., Muto, A., Arai, K., Watanabe, S. (2003) Analysis of the 5Õ promoters for human IL-3 and GM-CSF receptor a genes. Biochem. Biophys. Res. Comm., 300, 600-608

Kurita, R., Sagara, H., Aoki, Y., Link, B. A., Arai, K., Watanabe, S. (2003) Suppression of lens growth by aA-crystallin promoter-driven expression of diphtheria toxin results in disruption of retinal cell organization in zebrafish. Dev. Biol. 255, 113-127

Mitsui, T., Watanabe, S., Taniguchi, Y., Hanada, S., Ebihara, Y., Sato, T., Heike, T., Mitsuyama, M., Nakahata, T., Tsuji, K. (2003) Impaired neutrophil maturation in truncated murine G-CSF receptor-transgenic mice. Blood, 101, 2990-2995

Iwasaki-Arai, J., Iwasaki, H., Miyamoto, T., Watanabe, S., Akashi, K. (2003) Enforced GM-CSF signals do not support lymphopoiesis, but instruct lymphoid to myelomonocytic lineage conversion. J. Exp. Med. 197, 1311-1322

Iwasaki, H., Mizuno, S., Wells, R. A., Cantor, A. B., Watanabe, S., Akashi, K. (2003) GATA-1 converts lymphoid and myelomonocytic progenitors into the megakaryocyte/erythrocyte lineages. Immunity, 19, 451-462