We are currently focusing on molecular mechanisms underlying TRAF6-mediated activation of signal transduction pathways and how TRAF6 is involved in osteoclastogenesis and self-tolerance. In addition, NF-kB is constitutively activated in various cancer cells and this activation is likely involved in the malignancy of tumors. Thus, we are also investigating the molecular mechanisms of the constitutive activation of NF-kB and how this activation leads to the malignancy of breast cancers and adult T cell leukemia (ATL). In addition, we are investigating novel molecular mechanisms how tumor microenvironments and inflammation are regulated.
Division of Cellular and Molecular Biology
Head | INOUE Jun-ichiro |
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Location | General Research Building 1F |
Website |
Division of Cellular and Molecular Biology website (Japanese only) |
Annual Report |