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1.  Shimoyama, M., Seki, S., Nagai, M., Minato, K., Kitamura, T., Hoshino, H., Miwa, M., Tobinai, K., Nagoshi, H., Oosuga, T. and Sugimura, T. (1984) Clinical implication of anti-HTLV antibody titer, abnormal lymphocytes in HTLV carriers and HTLV genome negative adult T-cell leukemia-lymphoma.  Int. Symp. Princess Takamatsu Cancer Res. Fund. 15: 71-76.

 

2.  Kitamura, T., Takano, K., Hoshino, H., Shimotohno, K., Shimoyama, M., Miwa, M., Takaku, F. and Sugimura, T. (1985) Methylation pattern of human T-cell leukemia virus in vivo and in vitro: pX and LTR are hypomethylated in vivo. Int. J. Cancer 35: 629-635.

 

3.  Tamura, K., Unoki, T., Sagawa, K., Aratake, Y., Kitamura, T., Tachibana, N., Ohtaki, S., Yamaguchi, K. and Seita, M. (1985) Clinical features of OKT4+/OKT8+ adult T-cell leukemia. Leukemia Research 9: 1353-1359.

 

4.  Miwa, M., Shimotohno, K., Kitamura, T., Shima, H., Shimizu, N., Ootsuyama, Y., Tsujimoto, A., Watanabe, S., Shimoyama, M. and Sugimura, T. (1987) HTLV and ATL. Viruses and Human Cancer p131-140 (Alan R. Liss, Inc. New York).

 

5.  Fukamachi, H., Tojo, A., Saito, T., Kitamura, T., Nakata, M., Urabe, A. and Takaku, F. (1987) Internalization of radioiodinated erythropoietin and the ligand-induced modulation of its receptor in murine erythroleukemic cells. Int. J. Cell Cloning 5: 209-219.

 

6.  Fukamachi, H., Saito, T., Tojo, A., Kitamura, T., Urabe, A. and Takaku, F. (1987) Binding of erythropoietin to CFU-E derived from fetal mouse liver cells. Exp. Hematol. 15: 833-837.

 

7.  Kitamura, T., Tojo, A., Fukamachi, H., Akahane, K., Saito, T., Urabe, A. and Takaku, F. (1988) Characterization of the erythropoietin receptor on a Friend murine erythroleukemic cell clone, TSA8. Acta Haematol. Jpn. 51: 677-685.

8.  Tsao, C.-J., Tojo, A., Fukamachi, H., Kitamura, T., Saito, T., Urabe, A. and Takaku, F. (1988) Expression of functional erythropoietin receptors on interleukin 3-dependent murine cell lines. J. Immunol. 140: 89-93.

 

9.  Urabe, A., Kitamura, T., and Takaku, F. (1988) Clinical application of erythropoietin. Acta Haematol. Jpn. 51: 1355-1359.

 

10.  Akahane, K., Tojo, A., Fukamachi, H., Kitamura, T., Saito, T., Urabe, A. and Takaku, F. (1989) Binding of iodinated erythropoietin to rat bone marrow cells under normal and anemic conditions. Exp. Hematol. 17: 177-182.

 

11.  Kitamura, T., Tojo, A., Kuwaki, T., Chiba, S., Miyazono, K., Urabe, A. and Takaku, F. (1989) Identification and analysis of human erythropoietin receptors on a factor- dependent cell line, TF-1. Blood 73: 375-80.

 

12.  Kitamura, T., Tange, T., Terasawa, T., Chiba, S., Kuwaki, T., Miyagawa, K., Piao, Y.-F., Miyazono, K., Urabe, A. and Takaku, F. (1989) Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin. J. Cell. Physiol.  140: 323-334.

 

13.  Kuwaki, T., Kitamura, T., Tojo, A., Matsuki, S., Tamai, Y., Miyazono, K. and Takaku, F. (1989) Characterization of human interleukin-3 receptors on a multi-factor-dependent cell line. Biochem. Biophys. Res. Commun. 161: 16-22.

 

14.  Shibuya, K., Chiba, S., Hino, M., Kitamura, T., Miyazono, K. and Takaku, F. (1989) Effects of ubenimex on proliferation and differentiation of human bone marrow cells and leukemic cell lines, and the possible mechanisms of its action. Exp. Hematol. Today p81-87 (N. C. Gorin & L. Douay, eds).

 

15.  Fukamachi, H., Tojo, A., Saito, T., Kitamura, T., Urabe, A. and  Takaku, F. (1989) Tunicamycin modulates binding of 125I-erythropoietin to friend erythroleukemia cells. Acta Haematol. Jpn. 52: 1-6.

 

16.  Hayashi, Y., Tange, T., Chi, L.-C., Ishida, T., Kitamura, T., Kitamura, K. and  Urano, Y. (1989) An autopsy case of myelodysplastic syndrome (MDS) : Diagnostic problems between MDS and the other haematopoietic disorders including acute myelofibrosis. Acta Haematol. Jpn.  52: 49-54.

 

17.  Kitamura, T., Akahane, K., Yuo, A., Kobayashi, Y., Urabe, A. and  Takaku, F. (1990) Heterogeneity of responsiveness to recombinant human erythropoietin in patients with myelodysplastic syndromes. Acta Haematol. Jpn.  53: 866-872.

 

18.  Chiba, S., Tojo, A., Kitamura, T., Urabe, A., Miyazono, K. and Takaku, F. (1990) Characterization and molecular features of the cell surface receptor for human granulocyte-macrophage colony-stimulating colony-stimulating factor. Leukemia  4: 29-36.

 

19.  Gorman, D. M., Itoh, N., Kitamura, T., Schreuers, J., Yonehara, S., Yahara, I., Arai, K. and Miyajima, A. (1990) Cloning and expression of a gene encoding an interleukin 3 receptor-like protein:Identification of another member of the cytokine receptor gene family. Proc. Natl. Acad. Sci. U.S.A. 87: 5459-5463.

 

20.  Hayashida, K., Kitamura, T., Gorman, D. M., Arai, K., Yokota, T. and Miyajima, A. (1990) Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor. Proc. Natl. Acad. Sci. U.S.A. 87: 9655-9659.

 

21. Schreurs, J., Sugimoto, K., Wang, H.-M., Nishida, J., Heike, T., Miyatake, S., Abe, E., Ninomiya-Tsuji, J., Muramatsu, M., Itoh, N., Gorman, D., Maruyama, K., Xie, G., Kitamura, T., Hatake, K., Hayashida, K., de Waal Malefijt, R., Shlomai, J., Ito, N., Yokota, T., Arai, K., Miyajima, A. and Arai, N. (1990) Lymphokine receptor signal transduction and regulation of lymphokine genes. Molecular Aspects of Immune Response and Diseases p33-45 (H. Kiyono, E. Jirillo and C. DeSimone eds., Raven Press, Inc. , New York).

 

22. Arai, N., Tsuboi, A., Iwai, Y., Miyatake, S., Yokota, K., Malefijt, R., Muramatsu, M., Matsuda, I., Nishida, J., Baldwin, R., Koyano-Nakagawa, N., Hayashida, K., Kitamura, T., Gorman, D., Sato, N., Hara, T., Shlomai, J., Yokota, T., Miyajima, A. and Arai, K. (1990) Regulation of IL-3, IL-4, and GM-CSF  genes and signal transduction by their receptors. Lymphokine Research 9: 551-553.

 

23. Miyatake, S., Yokota, T., Miyajima, A., Kitamura, T., Arai, N. and Arai, K. (1991) Molecular biology of lymphokines.  In: Molecular Mechanisms of Immune Regulation p35-77 (R. Srivastava, B.P. Ram, P. Tyle, Eds., VHC Publishers, Inc.: New York).

 

24.  Shibuya, K., Chiba, S., Hino, M., Kitamura, T., Miyagawa, K., Takaku, F. and Miyazono, K. (1991) Enhancing effect of ubenimex (Bestatin) on proliferation and differentiation of hematopoietic progenitor cells, and the suppressive effect on proliferation of leukemic cell lines via peptidase regulation. Biomed. & Pharmacother. 45: 71-80.

 

25. Shibuya, K., Chiba, S., Miyagawa, K., Kitamura, T., Miyazono, K. and Takaku, F. (1991) Structural and functional analysis of glycosylation on the distinct molecules of human GM-CSF receptors. Eur. J. Biochem. 198: 659-666.

 

26. Kitamura, T., Takaku, F. and Miyajima, A. (1991) IL-1 upregulates the expression of cytokine receptors on a factor-dependent human hemopoietic cell line, TF-1. Int. Immunol. 3: 571-577.

 

27. Kitamura, T., Hayashida, K., Sakamaki, K., Yokota, T., Arai, K. and Miyajima, A. (1991) Reconstitution of functional human granulocyte/macrophage colony-stimulating factor (GM-CSF): evidence that AIC2B is a subunit of murine GM-CSF receptor. Proc. Natl. Acad. Sci. U.S.A. 88: 5082-5086.

 

28. Kitamura, T., Sato, N., Arai, K. and Miyajima, A. (1991) Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors. Cell 66: 1165-1174.

 

29. Takaki, S., Mita, S., Kitamura, T., Yonehara, S., Yamaguchi, N., Tominaga, A., Miyajima, A. and Takatsu, K. (1991) Identification of the second subunit of the murine interleukin-5 receptor: interleukin-3 receptor-like protein, AIC2B is a component of the high-affinity interleukin-5 receptor. EMBO J. 10: 2833-2838.

 

30. Shanafelt, A., Miyajima, A., Kitamura, T. and Kastelein, R.A. (1991) The amino-terminal helix of GM-CSF and IL-5 governs high affinity binding to their receptors. EMBO J. 10: 4105-4112.

31. Ward, J.C., Harris, K.W., Penny, L.A., Forget, B.G., Kitamura, T. and Winkelmann, J.C. (1992) A structurally abnormal erythropoietin receptor gene in a human erythroleukemia cell line. Exp. Hematol. 20: 371-373.

 

32. Miyajima, A., Kitamura, T., Harada, N., Yokota, T. and Arai, K. (1992) Cytokine receptor and signal transduction. Ann. Rev. Immunol. 10: 295-331.

 

33. Miyajima, A., Hayashida, K., Itoh, N., Schreurs, J., Gorman, D. M., Yonehara, S., Yahara, I., Takaki, S., Takatsu, K., Yokota, T., Arai, K. and Kitamura, T.  (1992) Molecular Structure of the Receptors for GM-CSF, IL-3 and IL-5. Molecular Biology of Hemopoiesis Vol 2 (Intercept Ltd, Hants, U.K.) pp119-130.

 

34. Kitamura, T. and Miyajima, A. (1992) Functional reconstitution of human interleukin-3 receptor. Blood 88:84-90.

 

35. Miyajima, A., Hara, T. and Kitamura, T. (1992) Common subunits of cytokine receptors and the functional redundancy of cytokines. Trends in Biochem. Sciences 17: 378-382.

 

36. Watanabe, Y., Kitamura, T., Hayashida, K. and Miyajima, A. (1992) Monoclonal antibody against the common b subunit (b c) of the human interleukin-3 (IL-3), IL-5, and granulocyte-macrophage colony-stimulating factor receptors shows upregulation of b c by IL-1 and tumor necrosis factor-a. Blood 80: 2215-2220.

 

37. Kawano, Y., Takaue, Y., Hirano, T., Watanabe, T., Abe, T., Shimizu, T., Sato, J., Saito, S.-I., Kitamura, T., Takaku, F. and Kuroda, Y. (1992) Production of interleukin 3 and granulocyte-colony-stimulating factor from stimulated blood mononuclear cells in patients with aplastic anemia. Exp. Hematol. 20: 1125-1128.

 

38. Sakamaki, K., Miyajima, I., Kitamura, T. and Miyajima, A. (1992) Critical cytoplasmic domains of the common b subunit of the human GM-CSF, IL-3, and IL-5 receptors for growth signal transduction and tyrosine phosphorylation. EMBO J. 11:3541-3549.

 

39. Wada, G.H., Indelicata, S.R., Meyer, L., Kitamura, T., Miyajima, A., Kirk, G., Muir, T. and Parce, J.W. (1993) GM-CSF triggers a rapid, glucose dependent extracellular acidification by TF-1 cells: evidence for sodium/proton antiporter and PKC mediated activation of acid production. J. Cell. Physiol. 154:129-138.

 

40. Stocking, C., Bergholz, U., Friel, J., Klingler, K., Starke, C., Kitamura, T., Miyajima, A. and Ostertag, W. (1993) Distinct classes of factor-dependent mutants can be isolated after retroviral mutagenesis of a human myeloid stem cell line. Growth Factor 8, 197-209.

 

41. Hoang, T., De Lean, A., Haman, A., Beauchemin, V., Kitamura, T. and Clark S.C. (1993) The structure and dynamics of the GM-CSF receptor defined by the ternary complex model. J. Biol. Chem. 268:11881-11887.

 

42. Takaki, S., Murata, Y., Kitamura, T., Miyajima, A., Tominaga, A. and Takatsu, K. (1993) Reconstitution of the functional receptors for murine and human interleukin 5. J. Exp. Med. 177, 1815-1820.

 

43. Lappi, D.A., Martineau, D., Sarmientos, P., Garofano, L., Arandra, A.P., Kitamura, T., Miyajima, A., and Baird, A. (1993) Characterization of a saporin mitotoxin specifically cytotoxic to cells bearing the granulocyte-macrophage colony-stimulating factor receptor. Growth Factor 9: 31-39.

 

44. Sakamaki, K., Wang, H.-M., Miyajima, I., Kitamura, T., Todokoro, K., Harada, N., and Miyajima, A. (1993) Ligand-dependent activation of  chimeric receptors with the cytoplasmic domain of the interleukin-3 receptor b subunit (bIL-3). J. Biol. Chem. 25: 15833-15839.

 

45. Sato, N., Caux, C., Kitamura, T., Watanabe, Y., Arai, K., Banchereau, J. and Miyajima, A. (1993) Expression and factor-dependent modulation of the IL-3 receptor subunits on human hemopoietic cells. Blood 82: 752-761.

 

46. Milatovich, A., Kitamura, T., Miyajima, A., and Francke, U. (1993) Gene for the alpha subunit of the human interleukin 3 receptor (IL3RA) localized to the X-Y pseudoautosomal region. Amer. J. Hum. Genet. 53: 1146-1153.

 

47. Kitamura, T., Ogorochi, T., and Miyajima, A. (1994) Multimeric cytokine receptors.  Trends in Endocrinology and Metabolism 5: 8-14.

 

48. Kitamura, T. and Miyajima, A. (1994) IL-3 receptor: Structure and signal transduction. in "Signal transduction through growth factor receptors", vol 3, 31-50, (Y. Kitagawa, Sasaki, R. eds. JAI Press Inc. Greenwich).

 

49. Rao, P., Kitamura, T., Miyajima, A., and Mufson, R. (1995) Human IL-3 receptor signaling: Rapid induction of phosphatidylcholine hydrolysis is dependent on tyrosine phosphorylation in transfected NIH3T3 cells. J. Immunol. 154: 1664-1674.

 

50. Kitamura, T., and Miyajima, A. (1995) Structure and function of the receptors for granulocyte/macrophage colony-stimulating factor. Leukocyte Typing V (Schlossman et al. eds.) 1868-1870.

 

51. Kitamura, T., Onishi, M., Kinoshita, S., Shibuya, A., Miyajima, A., and Nolan, G.P. (1995) Efficient screening of retroviral cDNA expression libraries.  Proc. Natl. Acad. Sci. U.S.A. 92: 9146-9150.

 

52. Wakao, H., Harada, N., Kitamura, T., Mui, A.L.F., and Miyajima, A. (1995) Interleukin-2 and erythropoietin activate STAT5/MGF via distinct pathways. EMBO J. 14, 2527-2535.

 

53. Onishi, M., Kinoshita, S., Morikawa, Y., Shibuya, A., Phillips, J., Lanier, L.L., Gorman., D.M., Nolan, G.P., Miyajima, A., and Kitamura, T. (1996) Applications of retrovirus-mediated expression cloning. Exp. Hematol. 24:324-329.

 

54. Onishi, M., Mui, A. L-F., Morikawa, Y., Cho, L., Kinoshita, S., Nolan, G.P., Miyajima, A., and Kitamura, T. (1996) Identification of an oncogenic form of the thrombopoietin receptor MPL using retrovirus-mediated gene transfer. Blood 88, 1399-1406.

 

55. Mui, A. L-F., Wakao, H., Kinoshita, T., Kitamura, T., and Miyajima, A. (1996) Dominant negative STAT5 inhibits interleukin-3-dependent proliferation. EMBO J. 15, 2245-2433.

 

56. Shibuya, A., Campbell, D., Hunnum, C., Yssel, H., Franz-Bacon, K., Kitamura, T., Nicholl, J., Sutherland, G.R., Lanier, L. L. and Phillips, J. H. (1996)  DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocyte. Immunity 4, 573-581.

 

57. Morikawa, Y., Tohya, T., Hara, T., Kitamura, T., and Miyajima, A.  (1996) Expression of the IL-3 receptor in testis. Biochem. Biophys. Res. Comm. 226, 107-112.

 

58. Nakamura, S., Stock, D.W., Wydner, K.L., Bollekens, J.A., Takeshita, K., Nagai, B.M., Chiba, S., Kitamura, T., Freeland, T.M., Zhao, Z., Minowada, J., Lawrence, J.B., Weiss, K.M., and Ruddle, F.H. (1996) Genomic analysis of a new mammalian distal-less gene: Dlx7. Genomics 38, 314-324.

 

59. Kawakami, Y., Miura, T., Bissonette, R., Hata, D., Khan, W.N., Kitamura, T., Maeda-Yamamoto, M., Hartman, S.E., Yao, L., Alt, F.W., and Kawakami, T. (1997)  Bruton's tyrosine kinase (Btk) regulates the JNK/SAPK kinase activity. Proc. Natl. Acad. Sci. U.S.A. 94, 3938-3942.

 

60. Ito, K., Ueda, Y., Kokubun, M., Urabe, M., Inaba, T., Mano, H., Hamada, H., Kitamura, T., Mizoguchi, H., Sakata, T., Hasegawa, M. and Ozawa, K. (1997) Development of a novel selective amplifier gene for controllable expansion of transduced hematopoietic cells. Blood 90, 3884-3892.

 

61. Onishi, M., Nosaka, T., and Kitamura, T. (1998) Cytokine receptors: Structures and signal transduction. Int. Rev. Immunol. 16:617-634.

 

62. Kitamura, T. (1998) New experimental approaches in retrovirus-mediated expression screening.  Int. J. Hematol. 67:351-359.

 

63. Hata, D., Kawakami, Y., Inagaki, N., Lantz, C.S., Kitamura, T., Khan, W.N., Tashiro, M., Maeda-Yamamoto, M., Miura, T., Han, W., Hartman, S.E., Yao, L., Nagai, H., Goldfeld, A.E., Alt, F.W., Galli, S.J., Witte, O.N., and Kawakami, T. (1998) Involvement of Brutonfs tyrosine kinase in FceRI-dependent mast cell degranulation and cytokine production.  J. Exp. Med. 187, 1235-1247.

 

64. Morikawa, Y., Nishida, H., Misawa, K., Nosaka, T., Miyajima, A., Senba, E. and Kitamura, T. (1998) Induction of synaptosomal-associated protein-23kd (SNAP-23) by various cytokines. Blood 92, 129-135.

 

65. Onishi, M., Nosaka, T., Misawa, K., Mui, A.L.-F., Gorman, D., McMahon, M., Miyajima, A., and Kitamura, T. (1998) Identification and characterization of a constitutive active STAT5 mutant that promotes cell proliferation. Mol. Cell. Biol. 18:3871-3879.

 

66. Jinno, A., Shimizu, N., Soda, Y., Haraguchi, Y., Kitamura, T, and Hoshino, H. (1998) Identification of the chemokine receptor TER1/CCR8 expressed in brain-derived cells and T-cells as a new coreceptor for HIV-1 infection. Biochem. Biophys. Res. Commun. 243:497-502.

 

67. Kawashima, T., Kawasaki, H., Kitamura, T., Nojima, Y., and Morimoto, C. (1998) Interleukin-12 induces tyrosine phosphorylation of an 85-kDa protein associated with the interleukin-12 receptor b1 subunit. Cell. Immunol. 186:39-44.

 

68. Kitamura, T., Onishi, M, Yahata, T., Kanakura, Y., and Asano, S. Activating mutations of the transmembrane domain of MPL in vitro and in vivo: Incorrect sequence of MPL-K, an alternative spliced form of MPL. (1998) Blood 92:2596-2597.

 

69. Dairaghi, D.J., Premack, B.A., Kitamura, T., Soo, K.S., Bacon, K.B., and Schall, T.J. (1998) RANTES-induced activation correlates with CD3 expression. J. Immunol. 168:426-433.

 

70. Duan, Y., Naruse, T., Yamaguchi, Y., Nakamura, M., Kawashiam, T., Morikawa, Y., Kitamura, T., and Suda, T. (1998) Expression and functional analysis of a hemopoietic progenitor antigen, NJ-1 (114/A10), in a megakaryocytic lineage.  Biochem. Biophys. Res. Commun. 253, 401-406.

 

71. Yang, Y-L., Lei, G., Xu, S., Holland, C.A., Kitamura, T., Hunter, K. and Cunningham, J.M. (1999) Receptors for polytropic and xenotropic murine leukemia viruses encoded by a single gene at Rmc1. Nature Genetics 21, 216-219.

 

72. Nosaka, T., Onishi, M., Kawashima, T., Yamada, K., Misawa, K., Ariyoshi, K., Towatari, K., Saito, H., Tani, K., Asano, S., Miyajima, A., and Kitamura, T. (1999) Identification and characterization of constitutively active STAT5. Molecular Biology of Hematopoiesis 6 (Abraham N.G. et al. eds. Kluwer Academic/Plenum Publishers, New York) pp277-287.

 

73. Mukasa, R., Homma, T., Ohtsuki, T., Hosono, O., Souta, A., Kitamura, T., Fukuda, M., Watanabe, S., and Morimoto, C. (1999) Core 2-containing O-glycans on CD43 are preferentially expressed in the memory subset of human CD4 T cells. Int. Immunol. 11, 259-268.

 

74. Matsumura, I., Kitamura, T., Wakao, H., Hashimoto, K., Albanese, C., Downward, J., Pestell, R.G., and Kanakura, Y. (1999) Involvement of cyclin D1 in STAT5-mediated cell growth. EMBO J. 18, 1367-1377.

 

75. Nieborowska-Skorska, M., Wasik, M.A., Slupianek, A., Salomoni, P., Kitamura, T., Calabretta, B., and Skorski, T. (1999) Signal transducer and activator of transcription (STAT) 5 activation by BCR/ABL is dependent on intact Src homology (SH) 3 and SH2 domains of BCR/ABL and is required for leukemogenesis. J. Exp. Med. 189, 1229-1242.

 

76. Kojima, T., and Kitamura, T. (1999) A signal sequence trap based on a constitutively active cytokine receptor. Nature Biotechnol. 17, 487-490.

 

77. Yagisawa, M., Saeki, K., Okuma, E., Kitamura, T., Kitagawa, S., Hirai, H., Yazaki, Y., Takaku, F., and Yuo, A. (1999) Signal transduction pathways in normal human moncytes stimulated by cytokines and mediators: comparative study with normal human neutrophils or transformed cells and the putative roles in functionality and cell biology. Exp. Hematol. 27, 1063-1076.

 

78. Shimizu, N., Soda, Y., Kanbe, K., Jinno, A., Kitamura, T., and Hoshino, H. (1999) An orphan G protein-coupled receptor, GPR1, act as a determinant co-receptor allowing replication of human immunodeficiency virus type 1 and type 2 in brain-derived cells. J. Virol. 258, 5231-5239.

 

79. Soda, Y., Shimizu, N., Jinno, A., Liu, H.Y., Kanbe, K., Kitamura, T., and Hoshino, H. (1999) Establishment of a new system for determination of coreceptor usages of HIV based on the human glioma NP-2 cell line. Biochem. Biophys. Res. Commun. 258, 313-321.

 

80. Nosaka, T., Kawashima, T., Misawa, K., Ikuta, K., Mui, A.L.F. and Kitamura, T. (1999) STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells. EMBO J. 18, 4754-4765.

 

81. Ye, S.K., Maki, K., Kitamura, T., Sunaga, S., Akashi, K., Domen, J., Weissman, I.L., Honjo, T. and Ikuta, K. (1999) Induction of germline transcription in the TCRg locus by Stat5: implications for accessibility control by the IL-7 receptor. Immunity 11:213-223.

 

82. Kubota, N., Terauchi, Y., Miki, H., Tamemoto, H., Yamauchi, T., Komeda, K., Satoh, S., Nakano, R., Ishii, C., Sugiyama, T., Eto, K., Tsubamoto, Y., Okuno, A., Murakami, K., Sekihara, Hi., Hasegawa, G., Naito, M., Toyashima, Y., Tanaka, S., Shiota, K., Kitamura, T., Fujita, T., Ezaki, O., Aizawa, S., Nagai, R., Tobe, K., Kimura, S., and Kadowaki, T. (1999) PPAR mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mollecular Cell 4: 597-609.

 

83. Tsukamoto, T., Huang, T., Guzman, R.C., Chen, X., Pascual, R.V., Kitamura, T., and Nandi, S. (1999) Isolation of oncogenes from rat mammary tumors by a highly efficient retrovirus expression cloning system. Biochem. Biophys. Res. Commun. 265, 7-12.

 

84. Yamada, K., Ariyoshi, K., Onishi, M., Miyajima, A., Hayakawa, F., Towatari, M., Saito, H., Oka, Y., Asano, S., Nosaka, T. and Kitamura, T. (2000) Constitutively active STAT5A and STAT5B in vitro and in vivo: mutation of STAT5 is not a frequent cause of leukemogenesis. Int. J. Hematol. 71, 46-54.

 

85. Kitamura, T. and Morikawa, Y. (2000) Isolation of cDNAs for T cell antigens by retrovirs-mediated expression cloning.  T Cell Protocols, Methods in Molecular Biology. (Kearse, K.P. ed. Humana Press, Totowa, New Jersey) pp 143-152.

 

86. Hayakawa, F., Towatari, M., Kiyoi, H., Tanimoto, M., Kitamura, T., Saito, H., and Naoe, T. (2000) Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3 dependent cell lines. Oncogene 19:624-631.

 

87. Zhao, M., Kiyoi, H., Yamamoto, Y., Ito, M., Towatari, M., Ohmura, S., Kitamura, T., Ueda, R., Saito, H., and Naoe, T. (2000) In vivo treatment of mutant FLT-3-transformed murine leukemia with a tyrosine kinase inhibitor. Leukemia 14: 374-378.

 

88. Machida, K., Matsuda, S., Yamaki, K., Senga, T., Thant, A.A., Kurata, H., Miyazaki, K., Hayashi, K., Okuda, T., Kitamura, T., Hayakawa, T., and Hamaguchi, M. (2000) v-Src suppresses SHPS-1 expression via the Ras-MAP kinase pathway to promote the oncogenic growth of the cells. Oncogene 19: 1710-1718.

 

89. Nosaka, T., and Kitamura, T. Jaks and STATs in hematopoietic cells. (2000) Int. J. Hematol. 71: 309-319.

 

90. Fujio, K., Nosaka, T., Kojima, T., Kawashima, T., Yahata, T., Copeland, N.G., Gilbert, D.J., Jenkins, N.A., Yamamoto, K, Nishimura, T. and Kitamura, T. (2000) Molecular cloning of a novel type I cytokine receptor similar to the common gamma chain. Blood 95:2204-2211.

 

91. Misawa, K., Nosaka, T., Kojima, T., Hirai, M. and Kitamura, T. (2000) Molecular cloning and characterization of a mouse homolog of human TNFSF14, a member of the TNF superfamily. Cytogenetics and Cell Genetics 89:89-91.

 

92. Misawa, K., Morita, S., Nosaka, T., Kaneko, A., Nakahata, T., Asano, S. and Kitamura, T. (2000) A method to identify cDNAs based on localization of green fluorescent protein fusion products. Proc. Natl. Acad. Sci. U.S.A. 97:3062-3066.

 

93. Morita, S., Kojima, T., and Kitamura, T. (2000) Plat-E: an efficient and stable system for transient packaging of retroviruses. Gene Therapy 7:1063-1066.

 

94. Tsuruga, H., Kumagai, H., Kojima, T., and Kitamura, T. (2000) Identification of novel membrane and secreted proteins upregulated during adipocyte differentiation. Biochem. Biophys. Res. Commun. 272:293-297.

 

95. Fujio, K., Misaki, Y., Setoguchi, K., Morita, S., Kawahata, K., Nosaka, T., Yamamoto, K., and Kitamura, T. (2000) Functional reconstitution of Class-II MHC-restricted T cell immunity mediated by retroviral transfer of the ƒΏƒΐTCR complex. J. Immunol.165: 528-533.

 

96. Kojima, T., Morikawa, Y., Copeland, N.G., Gilbert, D.J., Jenkins, N.A., Senba, E.  and Kitamura, T. (2000) Troy, a newly identified member of the tumor necrosis factor receptor superfamily, exhibits a homology with Edar and is expressed in embryonic skin and hair follicles. J. Biol. Chem. 275: 20742-20747.

 

97. Odajima, J., Matsumura, I., Sonoyama. J., Daino, H., Kawasaki, A., Tanaka, H., Inohara, N., Kitamura, T., Downward, J., Nakajima, K., Hirano, T., and Kanakura, Y. (2000) Full oncogenic activities of v-src are mediated by multiple signaling pathways; ras as an essential mediator for cell survival. J. Biol. Chem. 275, 24096-24105.

 

98. Furumoto, Y., Kawamoto, K., Masaki, S., Kitamura, T., Okumura, K., and Ra, C. (2000) Polymorphism in FceRI b chain do not affect IgE-mediated mast cell activation. Biochem. Biophys. Res. Commun. 273: 765-771.

 

99. Ariyoshi, K., Nosaka, T., Yamada, K., Onishi, M., Miyajima, A., and Kitamura, T. (2000) Constitutive activation of STAT5 by a point mutation in the SH2 domain. J. Biol. Chem. 275: 24407-24413.

 

100. Onai, N., Zhang, Y.-Y., Yoneyama, H., Kitamura, T., Ishikawa, S., and Matsushima, K. (2000) Impairment of lymphopoiesis and myelopoiesis in mice reconstituted with bone marrow-hematopoietic progenitor cells expressing dominant negative SDF-1, Intrakine. Blood 96, 2074-2080.

 

101. Kawashima, T., Hirose, K., Satoh, T., Ikeda, Y., Kaziro, Y., Nosaka, T. and Kitamura, T. (2000) MgcRacGAP is involved in the control of growth and differentiation of hematopoietic cells. Blood 96, 2116-2124.

 

102. Schwaller, J., Parganas, E., Wang, D., Cain, D., Aster, J.C., Williams, I.R., Lee, C-K., Gerthner, R., Kitamura, T., Frantsve, J., Anastasiadou, E., Loh, M.L., Levy, D.E., Ihle, J.N., and Gilliland, D.G. (2000) Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK. Molecular Cell 6, 693-704.

 

103. Setoguchi, K., Misaki, Y., Araki, Y., Fujio, K., Kawahata, K., Kitamura T. and Yamamoto K. (2000) Antigen-specific T cells transduced with interleukin-10 ameliorate experimentally induced arthritis without impairing the systemic immune response to the antigen. J. Immunol. 165:5980-5986.

 

104. Sakamoto, H., Kitamura, T., and Yoshimura, A. (2000) Mitogen-activated protein kinase plays an essential role in the erythropoietin-dependent proliferation of CTLL-2 cells. J. Biol. Chem. 275:35857-35862.

 

105. Sasaki, A., Yasukawa, H., Shouda, T., Kitamura, T., Dikic, I., and Yoshimura, A. (2000) CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2. J. Biol. Chem. 275, 29338-29347.

 

106. Sugiyama, T., Kumagai, H., Morikawa, Y., Wada, Y., Sugiyama, A., Yasuda, K., Yokoi, N., Kojima, T., Nosaka, T., Senba, E., Kimura, S., Kadowaki, T., Kodama, T., and Kitamura, T. (2000) A novel low-density lipoprotein receptor-related protein mediating cellular uptake of apolipoprotein E-enriched b-VLDL in vitro. Biochemistry 39, 15817-15825.

 

107. Kagami, S., Nakajima, H., Suto, A., Hirose, K., Suzuki, K., Morita, S., Kato, I., Saito, Y., Kitamura, T., and Iwamoto, I. (2001) Role of Stat5a in T Helper Cell Differentiation. Blood 97:2358-2365.

 

108. Hirose, K., Kawashima, T., Iwamoto, I., Nosaka, T., and Kitamura, T. (2001) MgcRacGAP is involved in cytokinesis through associating with mitotic spindle and midbody. J. Biol. Chem. 276:5821-5828.

 

109. Kamizono, S., Hanada, T., Yasukawa, H., Minoguchi, S., Kato, R., Minoguchi, M., Hattori, K., Morita, S., Kitamura, T., Kato, H., Nakayama, K., and Yoshimura, A. (2001) The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2. J. Biol. Chem. 276:12530-12538.

 

110. Kawashima, T., Murata, K., Akira, S., Tonozuka, Y., Minoshima, Y., Feng, S., Kumagai, H., Tsuruga, H., Ikeda, Y., Asano, S., Nosaka, T., and Kitamura, T. (2001) STAT5 induces macrophage differentiation of M1 leukemia cells through activation of IL-6 production mediated by NF-kB p65. J. Immunol. 167:3652-3660.

 

111. Tonozuka, Y., Fujio, K., Sugiyama, T., Nosaka, T., Hirai, M., and Kitamura, T. (2001) Molecular cloning of a human novel type I cytokine receptor related to Delta1. Cytogenetics and Cell Genetics 93:23-25.

 

112. Ishido, M., Yamamoto, A., Kitamura, T., Nagayama, K., and Ohashi, M. Cholesterol requirement for receptor transport from multivesicular late endosomes to the Golgi. (2001) J. Cell Science 114:1965-1976.

 

113. Tulin, E.E., Onoda, N., Maeda, M., Hasegawa, M., Nosaka, T., Nomura, H., Asano, S., and Kitamura, T. (2001) A novel secreted form of immune suppressor factor with high homology to vacuolar ATPase identified by forward genetic approach of functional screening based on cell proliferation. J. Biol. Chem. 276:27519-27526.

 

114. Kimura, M., Koseki, Y., Yamashita, M., Watanabe, N., Shimizu, C., Katsumoto, T., Kitamura, T., Taniguchi, M., Koseki, H., and Nakayama, K. (2001) Regulation of Th2 cell differentiation by mel-18, a mammalian polycomb group gene. Immunity, 15: 275-287.

 

115. Senga, T., Iwamoto, T., Kitamura, T., Miyake, Y., and Hamaguchi, M. (2001) JAK/Stat3 dependent activation of RalGDS/Ral pathway in M1 mouse myeloid leukemic cells. J. Biol. Chem. 276:32678-32681.

 

116. Frasor, J., Park, K.-S., Byers, M., Telleria, C., Kitamura, T., Yu-Lee, L., Djiane, J., Park-Sarge, O.-K., and Gibori, G. (2001) Differential roles for Stat5a and Stat5b in prolactin stimulation of estrogen receptor a and b transcription. Molecular Endcrinol. 15: 2172-2181.

 

117. Yamamoto, S., Yamamoto, N., Kitamura, T., Nakamura, K., and Nakafuku, M. (2001) Proleferation of parenchymal neural progenitors in response to injury in the adult rat spinal cord. Exp. Neurol., 172: 115-127.

 

118. Tokoro, Y., Shibuya, K., Osawa, M., Tahara-Hanaoka, S., Iwama, A., Kitamura, T., Nakauchi, H., and Shibuya, A. (2001) Molecular cloning and characterization of mouse tspan-3, a novel member of the tetraspanin superfamily, expressed on resting dendritic cells. Biochem. Biophys. Res. Commun. 288: 178-183.

 

119. Yamashita, Y., Kajigaya, S., Yoshida, K., Ueno, S., Ota, J., Ohmine, K., Ueda, M., Miyazato, A., Ohya, K., Kitamura, T., Ozawa, K., and Mano, H. (2001) Sak serine-threonine kinase acts as an effector of Tec tyrosine kinase. J. Biol. Chem. 276: 39012-39020.

 

120. Ueno, M., Igarashi, K., Kimura, N., Okita, K., Takizawa, M., Nobuhisa, I., Kojima, T., Kitamura, T., Morgan, S.M., Shiomura, T., Suda, T., Nakashima, K., and Taga, T. (2001) Identification of an embryonic dorsal aorta specific gene, endomucin, and its inhibitory activity on cell adhesion. Biochem. Biophys. Res. Commun. 287: 501-506.

 

121. Ye, S.K., Agata, Y., Lee, H.C., Kurooka, H., Kitamura, T., Shimizu, A., Honjo, T. and Ikuta, K. (2001) The IL-7 receptor controls the accessbility of the TCRg locus by Stat5 and histone acetylation. Immunity 15: 813-823.

 

122. Yamamoto, S., Nagao, M., Kitamura, T., Nakatomi, H., Sugimori, M., Kosako, H., Yamamoto, N., Takebayashi, H., Weinmaster, G., Nakamura, K., and Nakafuku, M. (2001) Transcription factor expression and Notch-dependent regulation of neural progenitors in the adult rat spinal cord. J. Neurosci. 21: 9814-9823.

 

123. Arakawa, M., Nakayama, Y., Hara, T., Shiozuka, M., Takeda, S., Kaga, K., Kondo, S., Morita, S., Kitamura, T., and Matsuda, R. (2001) Negamycin can restore dystrophin in mdx sskeletal muscle. Acta Myologica 20:154-158.

 

124. Kitamura, T., Kawashima, T., Minoshima, Y., Tonozuka, Y., Hirose, K., and Nosaka, T. (2001) Role of MgcRacGAP/CYK4 as a regulator of the small GTPase Rho family in cytokinesis and cell differentiation. Cell Structure and Function, 26:645-651.

 

125. Tulin, E. E., Onoda, N., Hasegawa, M., Nosaka, T., Nomura, H. and Kitamura, T. (2002) Genetic approach and phenotype-based complementation screening for identification of stromal cell-derived proteins involved in cell proliferation. Exp. Cell Res. 272:23-31.

 

126. Tulin, E. E., Onoda, N., Hasegawa, M., Nomura, H. and Kitamura, T. (2002) Inhibition of human endothelial cell proliferation by ShIF, a vacuolar H+-ATPAse-like protein. Oncogene 21:844-848.

 

127. Sai, X., Kawamura, Y., Kokame, K., Yamaguchi, H., Shiraishi, H., Suzuki, R., Suzuki, T., Kawaichi, M., Miyata, T., Kitamura, T., De Strooper, B., Yanagisawa, K., and Komano, H. Endoplasmic reticulum stress-inducible protein, Herp, enhances presenilin-mediated generation of amyloid beta-protein. (2002) J. Biol. Chem. 277:12915-12920.

 

128. Nosaka, T. and Kitamura, T. (2002) Pim-1 expression is sufficient to induce cytokine independence in murin hematopoietic cells, but is dispensable for BCR-ABL-mediated transformation. Exp. Hematol. 30:697-702.

 

129. Nakamura, T., Ouchida, R., Kodama, T., Kawashima, T., Watanabe, S., Morimoto, C., Kitamura, T., and Tanaka, H. (2002) Cytokine receptor common b subunit-mediated STAT5 activation confers NFkB activation in murine pro B cell line Ba/F3 cells. J. Biol. Chem. 277:6254-6265.

 

130. Perez, O.D., Kinoshita, S., Hitoshi, Y., Payan, D.G., Kitamura, T., Nolan, G.P. and Lorens, J. (2002) Acitivation of the PKB/AKT pathway by ICAM-2. Immunity 16:51-65.

 

131. Nagai, Y., Akashi, S., Nagafuku, M., Ogata, M., Iwakura, Y., Akira, S., Kitamura, T., Kosugi, A., Kimoto, M., and Miyake, K. (2002) Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat. Immunol. 3:667-672.

 

132. Gugasyan, R., Quilici, C., I, S.T., Grail, D., Verhagen, A.M., Roberts, A., Kitamura, T., Dunn, A.R., and Lock, P. (2002) Dok-related protein negatively regulates T cell development ts RasGTPase activating protein and Nck docking sites. J. Cell Biol. 158:115-125.

 

133. Stoeclin, G., Colombi, M., Raineri, I., Leuenberger, S., Mallaun, M., Schmidlin, M., Gross, B., Lu, M., Kitamura, T., and Moroni, C. (2002) Functional cloning of BRF-1, a regulator of ARE-dependent mRNA turnover. EMBO J. 21:4709-4718.

 

134. Komano, H., Kawamura, Y., Shiraishi, H., Sai, X., Suzuki, R., Kawaichi, M., Kitamura, T., and Yanagisawa, K. (2002) A new functional screening system for the identification of DNA encoding a regulator of g-cleavage. J. Biol. Chem. 277:39627-39633.

 

135. Ezoe, S., Matsumira, I., Ishihara, K., Minegishi, N., Takahashi, S., Machii, T., Kitamura, T., Yamamoto, M., Enver, T., and Kanakura, Y. (2002) GATA-2 affects cytokine-dependent growth of hematopoietic cells through accumulation of p21WAF1 and p27Kip1 proteins. Blood 100:3512-3520.

 

136. Yujiri, T., Nawata, R., Takahashi, T., Sato, Y., Tanizawa, Y., Kitamura, T., and Oka, Y. (2003) MEK kinase 1 interacts with focal adhesion kinase and regulates insulin receptor substrate-1 expression. J. Biol. Chem. 278:3846-3851.

 

137. Ozawa, T., Sako, Y., Sato, M., Kitamura, T., and Umezawa, Y. (2003) A genetic approach to identifying mitochondrial proteins. Nat. Biotechnol. 21:287-293.

 

138. Minoshima, Y., Kawashima, T., Hirose, K., Tonozuka, Y., Kawajiri, A., Bao, Y-C., Deng, X., Tatsuka, M., Narumiya, S., May, W.S. Jr., Nosaka, T., Semba, K., Inoue, T., Satoh, T., Inagaki, M., and Kitamura, T. (2003) Phosphorylation by Aurora B converts MgcRacGAP to a RhoGAP during cytokinesis. Dev. Cell 4:549-560.

 

139. Nosaka, T., Morita, S., Kitamura, H., Nakajima, H., Shibata, F., Morikawa, Y., Kataoka, Y., Ebihara, Y., Kawashima, T., Itoh, T., Ozaki, K., Senba, E., Tsuji, K., Makishima, F., Yoshida, N., and Kitamura, T. (2003) Mammalian twisted gastulation is essential for skeleto-lymphogenesis. Mol. Cell. Biol. 23: 2969-2980.

 

140. Kitamura, T., Koshino, Y., Shibata, F., Nakajima, H., Nosaka, T., and Kumagai, H. (2003) Retrovirus-mediated gene transfer and expression cloning, powerful tools in functional genomics. Exp. Hematol. 31: 1007-1014.

 

141. Bao, Y-C., Tsuruga, H., Hirai, M., Kitamura, T., and Kumagai, H. (2003) Identification of a human cDNA sequence which encodes a novel membrane-associated protein containing a zinc metalloprotease motif. DNA Research 10: 123-128.

 

142. Murata, K., Kumagai, H., Kawashima, T., Irie, M., Nakajima, H., Tamitsu, K., Nosaka, T., Asano, S., and Kitamura, T. (2003) A novel tyrosine kinase inhibitor GTP14564 specifically inhibits constitutively active fms-like tyrosine kinase 3 through inactivation of STAT5. J. Biol. Chem. 278: 32892-32898.

 

143. Ueno, H., Sakita-Ishikawa, M., Morikawa, Y., Nakano, T., Kitamura, T., and Saito, M. (2003) A stromal cell-derived membrane protein that supports hematopoietic stem cells. Nat. Immunol. 4:457-463.

 

144. Hisaoka, T., Morikawa, Y., Kitamura, T., and Semba, E. (2003) Expression of a member of tumor necrosis factor receptor superfamily, TROY, in the developing and the adult mouse brain. Brain Research, 143: 105-109.

 

145. Takizawa, M., Nobuhisa, I., Igarashi, K., Ueno, M., Nakashima, K., Kitamura, T., and Taga, T. (2003) Requirement of gp130 signaling for the AGM hematopoiesis. Exp. Hematol. 31: 283-289, 2003.

 

146. Tahara, H., Fujio, K., Araki, Y., Setoguchi, K., Misaki, Y., Kitamura, T., and Yamamoto, K. (2003) Reconstitution of CD8+ T cells by retroviral transfer of the T-cell receptor ab chain genes isolated from a clonally expanded P815 infiltrating lymphocytes. J. Immunol. 171:2154-2160.

 

147. Kumagai, H., Oki, T., Tamitsu, K., Feng, S-Z., Ono, M., Nakajima, H., Bao, Y-C., Kawakami, Y., Nagayoshi, K., Copeland, N.G., Gilbert, D.J., Jenkins, N.A., Kawakami, T., and Kitamura, T. (2003) Identification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells. Biochem. Biophys. Res. Commun. 307: 719-729.

 

148. Nishiyama, C., Nishiyama, M., Ito, T., Masaki, S., Masuoka, N., Yamane, H., Kitamura, T., Ogawa, H., and Okumura, K. (2004) Functional analysis of PU.1 domains in monocyte-specific gene regulation. FEBS letters 561: 63-68.

 

149. Nishiyama, C., Nishiyama, M., Ito, T., Masaki, S., Maeda, K., Masuoka, N., Yamane, H., Kitamura, T., Ogawa, H., and Okumura, K. (2004) Overproduction of PU.1 in mast cell progenitors: its effect on monocyte- and mast cell-specific gene expression. Biochem. Byophys. Res. Commun. 313: 516-521.

 

150. Chamoto, K., Tsuji, T., Funamoto, H., Kosaka, A., Matsuzaki, J., Sato, T., Abe, H., Fujio, K., Yamamoto, K., Kitamura, T., Takeshima, T., Togashi, Y., and Nishimura, T. (2004) Potentiation of tumor eradiction by adoptive immunotherapy with T-cell receptor gene-transduced T-helper type 1 cells. Cancer Res. 64:386-390.

 

151. Nakayama, Y., Nara, N., Kawakita, Y., Takeshima, Y., Arakawa, M., Katoh, M., Morita, S., Iwatsuki, K., Tanaka, K., Okamoto, S., Kitamura, T., Seki, N., Matsuda, R., Matsuo, M., Saito, K. and Hara, T. (2004) Cloning of cDNA encoding a regeneration-associated muscle protease whose expression is attenuated in cell lines derived from Duchenne muscle dystrophy patients. American J. Pathol. 164: 1773-1782.

 

152. Ohtsuka M., Arase, H., Takeuchi, A., Yamasaki, S., Shiina, R., Suenaga, T., Sakurai, D., Yokosuka, T., Arase, N., Iwashima, M., Kitamura, M., Kitamura, T., Moriya, H., and Saito, T. (2004) NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling. Proc. Natl. Acad. Sci. USA. 101: 8126-8131.

 

153. Ikeda, Y., Imai, Y., Kumagai, H., Nosaka, T., Morikawa, Y., Hisaoka, T., Manabe, I., Maemura, K., Nakaoka, T., Imamura, T., Miyazono, K., Komuro, I., Nagai, R. and Kitamura, T. (2004) Vasorin, a novel TGF-b binding protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo. Proc. Natl. Acad. Sci. USA.101:10732-10737.

 

154. Nishizawa, H., Matsuda, M., Yamada, Y., Kawai, K., Suzuki, E., Makishima, M., Kitamura, T., and Shimomura, I. (2004) Musculin, a novel skeletal muscle-derived secretary factor. J. Biol. Chem. 279:19391-19395.

 

155. Tonozuka, Y., Minoshima, Y., Bao, Y.C., Moon, Y., Nakajima, H., Nosaka, T., Kawashima, T. and Kitamura, T. (2004) A GTPase activating protein binds STAT3 and is required for IL-6-induced STAT3 activation and differentiation of a leukemic cell line. Blood 104: 3550-3557.

 

156. Fukuchi, Y., Nakajima, H., Sugiyama, D., Hirose, I., Kitamura, T., and Tsuji, K. (2004) Human placenta-derived cells have mesenchymal stem/progenitor cell potential. Stem Cell 22:649-658.

 

157. Sasanuma, H., Tatsuno, A., Tsuji, K., Hidano, S., Morita, S., Kitamura, T., Kubo, M., Kitamura, D., and Goitsuka, R. (2004) Transcriptional regulation of SLP-76 family hematopoietic cell adaptor MIST/Clnk by STAT5. Biochem. Byophys. Res. Commun. 321:145-153.

 

158.Ono, R., Nakajima, H., Ozaki, K., Kumagai, H., Kawashima, T., Taki, T., Kitamura, T., Hayashi, Y., and Nosaka, T. (2005) Two-step model of leukemogenesis in multiple lineages by dimerization of MLL fusion protein. J Clin. Invest. in press.

 

159. Oceguera-Yanez, F., Kimura, K., Yasuda, S., Higasida, T., Kitamura, T., Hiraoka, Y., Haraguchi, N., and Narumiya, S. (2005) Ect-2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis. J. Cell Biol. 168:221-232.

 

160. Koma, Y., Ito, A., Watabe, K., Hirata, T., Mizuki, M., Yokozaki, H., Kitamura, T., Kanakura, T., and Kitamura, Y. (2005) Distinct role for c-kit receptor tyrosine kinase and SgIGSF adhesion molecule in attachment of mast cells to fibroblasts. Lab. Invest. 85: 426-435.

 

161. Oishi, Y., Manabe, I., Tobe, K., Tsushima, K., Shindo, T., Fujiu, K., Nishimura, G., Maemura, K., Yamauchi, T., Kubota, N., Suzuki, R., Kitamura, T., Akira, S., Kadowaki, T., and Nagai, R. (2005) Kruppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation. Cell Metabolism, in press.

 

162. Urano, A., Endoh, M., Wada, T., Morikawa, Y., Itoh, M., Kataoka, Y., Taki, T., Akazawa, H., Nakajima, H., Komuro, I., Yoshida, N., Hayashi, Y., Handa, H., Kitamura, T., and Nosaka T. Infertility with defective spermiogenesis in mice lacking AF5q31, the target of chromosomal translocation in human infant leukemia. Mol. Cell. Biol. in press.

 

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