Toward clinical practice from advanced stem cell biology.

Our major goals are to understand the mechanism of the intractable disease and establish the therapy of the disease through the several Stem Cells biology.

Current NewsMore News

2016/10/21

Research achievement, Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantarion" was published in "The NIKKEI SHINBUN".

2016/10/21

Research achievement, Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantarion" was published in "The ASAHI Shinbun".

2016/10/20

PRESS: Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantarion

Read more

2014/10/1

ARM lab was established.

Read more

PublicationsMore Publications

Yuki Taya, Yasunori Ota, Adam C Wilkinson, Ayano Kanazawa, Hiroshi Watarai, Masataka Kasai, Hiromitsu Nakauchi and Satoshi Yamazaki.
Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation. Science. Oct 20, 2016

Pre-transplantation blockade of TNF-α-mediated oxygen species accumulation protects hematopoietic stem cells.
Ishida T, Suzuki S, Lai CY, Yamazaki S, Kakuta S, Iwakura Y, Nojima M, Takeuchi Y, Higashihara M, Nakauchi H, Otsu M.
Stem Cells. 2016 Oct 18. doi: 10.1002/stem.2524.

Abstract on PubMed

Koide S, Oshima M, Takubo K, Yamazaki S, Nitta E, Saraya A, Aoyama K, Kato Y, Miyagi S, Nakajima-takagi Y, Chiba T, Matsui H, Arai F, Suzuki Y, Kimura H, Nakauchi H, Suda T, Shinkai Y, Iwama A. Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of non-hematopoietic genes. Blood. Jun 14 , 2016

Abstract on PubMed

Chen JY, Miyanishi M, Wang SK, Yamazaki S, Shnha R, Kao KS, Seita J, Sahoo D, Nakauchi H, Weissman IL. Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenyous perivascular niche. Nature. 530(7589):223-7, 2016.

Abstract on PubMed

Activity in the lab