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Metabolic changes in aging and disease

学友会セミナー

開催情報

開催日時 2023年10月30日(月)13:00~14:00
開催場所 1号館講堂
講師 Peter J Mullen, Ph.D.
所属・職名 Assistant Professor, Keck School of Medicine of University of Southern California 
演題 Metabolic changes in aging and disease
世話人
主たる世話人 中西 真(癌防御シグナル分野)
       山梨 裕司 (腫瘍抑制分野)
       
       

概要

Metabolites are used to make DNA, RNA, proteins, energy, hormones, and other molecules that are essential for health and healthy aging. My lab is focused on identifying how metabolism is dysregulated during cancer, viral infections, and aging. Here, I will present two unpublished stories: the first uses scRNA-seq to identify metabolic pathways that are changed specifically in the early stages of adenovirus infection, and shows that nutrient sensing to mTORC1 is impaired; and the second creates a metabolic atlas of aging in mice that will provide an invaluable resource to positively impact longevity research.