Looking at the insulin-like growth factor signaling through the zebrafish eyes

Dr. Duan is interested in genes that control the size of an animalor organ and the cellular and molecular mechanisms underlying their actions. His current research focuses on the insulin-like growth factor (IGF) signaling system, including the IGF ligands, IGF binding proteins, IGF receptors, and the downstream signal transduction mechanisms. A combination of molecular, biochemical, genetic, and genomic approaches are used to address physiological and cell biological questions. Both mammals and zebrafish are utilized as experimental models. This time he will present his recent works on IGFs and IGF bindingproteins.