東京大学医科学研究所

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学友会セミナー

学友会セミナー:2018年9月21日

開催日時: 2018年9月21日 15:00 ~ 16:00
開催場所: 2号館小講義室
講師: Ann Leen
所属: Associate professor, Center for Cell and Gene Therapy, Baylor College of Medicine
演題: T cell therapy for viruses and cancer
概要:

In recent years T cell therapy has emerged as a promising therapeutic for the treatment of both viral infections and cancer. Over the course of this lecture I will report on the outcomes of 75 patients infused with either donor-derived (n=21) or third party “off the shelf” (n=54) virus-specific T cells (VSTs) with activity against 5 common post-transplant viruses (EBV, CMV, Adv, BK, HHV6) that cause significant morbidity and mortality in immunocompromised hematopoietic stem cell transplant recipients. Furthermore, I will provide an update on our ongoing clinical trials using T cells targeting a wide spectrum of tumor-associated antigens [e.g. Survivin, MAGEA4, Synovial sarcoma X (SSX2), WT1, PRAME] expressed by hematological malignancies including Hodgkin and non-Hodgkin Lymphoma, multiple myeloma and leukemia.

世話人: 〇高橋 聡 (分子療法分野)
 四柳 宏 (感染症分野)