東京大学医科学研究所

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学友会セミナー

学友会セミナー:2017年6月19日

開催日時: 2017年6月19日 15:00 ~ 16:00
開催場所: 2号館小講義室
講師: Colleen Delaney
所属: Director, Program in Cord Blood Transplantation, Fred Hutchinson Cancer Research Center
Associate Professor, Pediatric Hematology/Oncology, University of Washington
Chief Medical Officer, Nohla Therapeutics
演題: Development of a Universal Donor Expanded Hematopoietic Stem and Progenitor Cell Product for Bridging Hematopoiesis
概要:

Dr. Delaney’s research interests focus on the role of the Notch signaling pathway in hematopoietic stem cell regulation and ex-vivo expansion of umbilical cord blood stem and progenitor cells for clinical applications. Her group has developed a novel and clinically feasible method for the ex vivo expansion of cord blood derived hematopoietic stem and progenitor cells in the presence of Notch ligands. This work was translated into a novel pilot study investigating the use of ex vivo expanded cord blood progenitors to augment conventional cord blood transplantation. She has since extended this work to investigate the potential of cryopreserved, non-HLA matched “off the shelf” ex vivo expanded cord blood progenitor cells to provide rapid but transient myeloid reconstitution in the setting of cord blood transplant and following dose-intensive chemotherapy.

世話人: 〇東條 有伸(分子療法分野)
  大津 真(幹細胞プロセシング分野)