The Institute of Medical Science, The University Of Tokyo

  1. Home
  2. Scientific Papers/Award

Scientific Papers/Award

HLA-class II and other gene loci associated with susceptibility to EGFR-mutated lung adenocarcinoma

Nature Communications, 2016, on line publication. DOI: 10.1038 / NCOMMS12451
Shiraishi K, Okada Y, Takahashi A, Kamatani Y, Momozawa Y, Ashikawa K, Kunitoh H, Matsumoto S, Takano A, Shimizu K, Goto A, Tsuta K, Watanabe S, Ohe Y, Watanabe Y, Goto Y, Nokihara H, Furuta K, Yoshida A, Goto K, Hishida T, Tsuboi M, Tsuchihara K, Miyagi Y, Nakayama H, Yokose T, Tanaka K, Nagashima T, Ohtaki Y, Maeda D, Imai K, Minamiya Y, Sakamoto H, Saito A, ShimadaY, Sunami K, Saito M Inazawa J, Nakamura Y, Yoshida T, Yokota J, Matsuda F, Matsuo K, Daigo Y, Kubo M, Kohno T*
Yu Miyazaki, Xiaofei Du, Shin-ichi Muramatsu, Christopher M. Gomez
Ichikawa K1, Kubota Y2, Nakamura T2, Weng JS3, Tomida T4, Saito H5, Takekawa M6

A muscle-liver-fat signalling axis is essential for central control of adaptive adipose remodelling

Nature Communications 6, Article number: 6693 doi:10.1038/ncomms7693
Noriaki Shimizu, Takako Maruyama, Noritada Yoshikawa, Ryo Matsumiya, Yanxia Ma, Naoki Ito, Yuki Tasaka, Akiko Kuribara-Souta, Keishi Miyata, Yuichi Oike, Stefan Berger, Günther Schütz, Shin'ichi Takeda & Hirotoshi Tanaka
Joseph M. Reynolds1 Young-Hee Lee1 Yun Shi2 Xiaohu Wang3 Pornpimon Angkasekwinai4 Kalyan C. Nallaparaju2 Stephanie Flaherty1 Seon Hee Chang2 Hiroshi Watarai5,6 and Chen Dong3
1. Department of Microbiology and Immunology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA 2. Department of Immunology and Center for Inflammation and Cancer, MD Anderson Cancer Center, Houston, TX 77054, USA 3. Institute for Immunology, Tsinghua University, Beijing 100084, China 4. Department of Medical Technology, Faculty of Allied Health Sciences, Thammasat University, Pathumthani 12120, Thailand 5. Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan 6. Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency (JST), 7, Gobancho, Chiyoda-ku, Tokyo 102-0076, Japan
Kazuo Tatebayashi, Katsuyoshi Yamamoto, Miho Nagoya, Tomomi Takayama, Akiko Nishimura, Megumi Sakurai, Takashi Momma & Haruo Saito
Andrea Marzi, Peter Halfmann, Lindsay Hill-Batorski, Frederike Feldmann, W. Lesley Shupert, Gabriele Neumann, Heinz Feldmann and Yoshihiro Kawaoka

Targeting cell surface ​TLR7 for therapeutic intervention in autoimmune diseases

Nature Communications 6, Article number: 6119 doi:10.1038/ncomms7119
Atsuo Kanno, Natsuko Tanimura, Masayuki Ishizaki, Kentaro Ohko, Yuji Motoi, Masahiro Onji, Ryutaro Fukui, Takaichi Shimozato, Kazuhide Yamamoto, Takuma Shibata, Shigetoshi Sano, Akiko Sugahara-Tobinai, Toshiyuki Takai, Umeharu Ohto, Toshiyuki Shimizu, Shin-ichiroh Saitoh & Kensuke Miyake
Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minatoku, Tokyo 108 8639, Japan Laboratory of Innate Immunity, Center for Experimental Medicine and Systems Biology, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minatoku, Tokyo 108 8639, Japan Japan Society for the Promotion of Science, 5-3-1, Kojimachi, Chiyodaku, Tokyo 102 0083, Japan Daiichi Sankyo Shinagawa R&D center, Daiichi Sankyo Co. Ltd., 1-chome, Hiromachi, Tokyo 140 8710, Japan Department of Dermatology, Kochi Medical School, Kochi University, Kohasu, Okocho, Nankoku 783 8505, Japan Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700 8558, Japan CREST, Japan Science and Technology Agency, 4-1-8, Honcho, Kawaguchi-shi, Saitama 332 0012, Japan Department of Experimental Immunology, Institute of Development, Aging and Cancer, Tohoku University, Seiryo 4-1, Sendai 980 8575, Japan Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113 0033, Japan

DNase II-dependent DNA digestion is required for DNA sensing by TLR9

Nature Communications 6, 5853 doi:10.1038/ncomms6853
Mei Po Chan, Masahiro Onji, Ryutaro Fukui, Kohki Kawane, Takuma Shibata, Shin-ichiroh Saitoh, Umeharu Ohto, Toshiyuki Shimizu, Glen N. Barber, and Kensuke Miyake
Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minatoku, Tokyo 108-8639, Japan Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan Faculty of Life Sciences, Department of Molecular Biosciences, Kyoto Sangyo University, Kyoto 603-8555, Japan CREST, JST, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan Department of Cell Biology and Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
Akiyama N1, Shinzawa M1, Miyauchi M1, Yanai H1, Tateishi R1, Shimo Y1, Ohshima D1, Matsuo K2, Sasaki I3, Hoshino K4, Wu G5, Yagi S5, Inoue JI1, Kaisho T6, Akiyama T7
1Division of Cellular and Molecular Biology, Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan. 2Laboratory of Cell and Tissue Biology, Graduate School of Medicine, Keio University, Shinjuku-ku, Tokyo 160-8582, Japan. 3Laboratory for Immune Regulation, World Premier International Research Center Initiative, Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan. 4Laboratory for Immune Regulation, World Premier International Research Center Initiative, Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan Laboratory for Inflammatory Regulation, Research Center for Allergy and Immunology, RIKEN Center for Integrative Medical Sciences, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan Department of Immunology, Faculty of Medicine, Kagawa University, Kita-gun, Kagawa 761-0793, Japan. 5Laboratory of Cellular Biochemistry, Department of Animal Resource Sciences, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan. 6Laboratory for Immune Regulation, World Premier International Research Center Initiative, Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan Laboratory for Inflammatory Regulation, Research Center for Allergy and Immunology, RIKEN Center for Integrative Medical Sciences, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan 7Division of Cellular and Molecular Biology, Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan