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The Institute of Medical Science, The University Of Tokyo

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Frontier Research Initiative


The Frontier Research Initiative is managed under the theme adopted by the University of Tokyo, "Promotion of Independence for Young Investigators" (representative: President Hiroshi Komiyama), funded by "Program for Improvement of Research Environment for Young Researchers" from the Ministry of Education, Culture, Sports, Science and Technology (MEXT). In cooperation with the university-wide program steering committee, the office of program supervision established within the Institute of Medical Science supports the research and training of mainly two Frontier Research Team Leaders and four Frontier Researchers. Various professors from within the Institute serve as mentors, offering guidance and advice on research and training matters.

Nakae Group

Our goals are to understand the molecular mechanism of development of allergic diseases such as asthma and dermatitis using gene-deficient mice.

Associate Professor (Project)

Susumu Nakae



Heissig Group

Stem cells can modulate tissue regeneration. The unique roles of the microenvironment, like stromal cells, chemokines, cytokines, adhesion molecules, and proteolytic enzymes, which regulate hematopoietic stem cells are currently being investigated. We seek to understand how hematopoietic cells are recruited and how they contribute to vessel formation (angiogenesis) of ischemic and malignant cancerous tissues.

Associate Professor (Project)

Beate Heissig


Heissig Group Website


Yamashita Group


Research Associate (Project)

Riu Yamashita



Yamamoto Group


Research Associate (Project) Katsuyoshi Yamamoto



Yokoyama Group


Research Associate (Project) Kazumasa Yokoyama