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Jan 16, 2009
Dear All Users,

SEMINAR ON THE BIOLOGICAL INTERPRETATION OF
HIGH-THROUGHPUT EXPRESSION DATA USING "ExPlain"

Date: January 27 (Tuesday) 14:00-16:30

Place: Human Genome Center, 4F Conference Room 402

Lecturers: Edgar Wingender, Prof. Dr.
Dept. of Bioinformatics, Director
University of Goettingen
President and CSO of BIOBASE GmbH

Ruy Jauregui, Ph. D.
R & D, BIOBASE GmbH

Language: English

Target: All people who want to use "ExPlain"
in their own research

Contents:
A great amount of high-throughput expression data has become available, but the biological interpretation of the expression profiles still remains a challenge.

"ExPlain" is an expression data analysis platform provided by BIOBASE. By using "ExPlain" algorithms a researcher can make gene ontology and functional analysis on the gene expression profiles, and also identify possible upstream causes and/or regulators that explain the observed expression. "ExPlain" algorithms can easily help to generate hypothesis on master regulators of intracelluar gene regulation and signal transduction processes. This becomes relevant both in basic research and applied science; "ExPlain" can directly facilitate the identification of prospective drug targets, causal biomarkers, and elucidation of cell differentiation mechanisms. "ExPlain" analysis supports various types of high-throughput data such as transcriptomics, proteomics and phosphoproteomics data, Chip-chip and Chip-seq data, as well as data on protein-protein interactions.

By using a temporary password, a participant may get into the server and experience the analysis work flow and the extensive data library which includes the databases TRANSFAC (transcription factors and position weight matrices), TRANSPATH (signal transduction networks) and TRANSPRO (whole genome promoters).

Anyone who wants to attend the lecture should fill the following form and send it by E-mail or Fax by 17:00 P.M. Jan 23 (JST) . If you have any special requests for this lecture, please add them to this form.

e-mail: hgc-lect@hgc.jp
FAX: 03-5449-5133

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