IMSUT Joint Research Project FY2012 Call for Proposals
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IMSUT Joint Research Project FY2012 Call for Proposals

IMSUT (Institute of Medical Sciences, the University of Tokyo) Call for Proposals "FY2012 IMSUT Joint Research Project" in the following three joint research areas.

(1) Joint Research Area: Development of Cutting Edge Medical Therapies

<Research topic>
  1. Bioinformatics based on genome-related data
  2. Clinical research applying genomic data
  3. Analysis of hematopoietic mechanisms and hematopoietic tumorigenesis, and development of novel treatments for hematopoietic malignancies
  4. Analysis of genes involved in solid cancers and development of novel treatments
  5. Development and manufacture of gene therapy vectors
  6. Treatment of infectious diseases, and coordinated analysis and treatment of their pathogenicity, and treatment-related technological development
  7. Fundamental research on molecular targeted therapy of immune diseases focusing on autoimmune disorders
  8. Elucidation of stem cell regulatory mechanisms using human stem cells (ES cells, iPS cells, hematopoietic stem cells, mesenchymal stem cells etc.) and investigation of related pathoetiology.
  9. Development of hematopoietic stem cell treatments with a view toward next-generation regenerative medicine
  10. Development of solid organ regeneration with a view toward next-generation regenerative medicine
(2) Joint Research Area: Disease Systems Biology

<Research topic>
  1. Mechanisms of stem cell and central nervous system differentiation
  2. Analysis of genes involved in bone metabolism
  3. Mechanisms of angiogenesis and lymphangiogenesis
  4. Regulation of germ cell generation, and models for this process
  5. Analysis of allergy and immune related genes
  6. Chromosome segregation abnormalities and cancer
  7. Tyrosine kinase-mediated signaling in cancer and other intractable diseases
  8. Transcriptional regulation and cancer development, Generation and maintenance of cancer stem cells
  9. Membrane-type matrix metalloproteinase and cancer
  10. Cancer and abnormalities in cell adhesion molecules
  11. Screening and application of small molecules that regulate protein interactions
  12. Antibody engineering for Systems Biology and Medicine
(3) Joint Research Area: Infectious Diseases and Immunology

<Research topic>
  1. Molecular, cellular and whole organism-level analysis of host factor/pathogen factor interactions involving influenza virus, Ebola virus, paramyxovirus, HIV, HTLV, herpes virus, HCV, HBV etc. or other emerging or re-emerging infectious diseases
  2. Host responses as these relate to the acquired immune system, pathogen sensors, etc. of the innate immune system as well as mucosal immunity of the gastrointestinal and respiratory tracts
  3. Technological development for reverse genetics, miRNA analysis or mucosal vaccines, etc.
  4. Research that requires use of the Amami Laboratory of Injurious Animals or Primate Laboratory

1. Program outline
The purpose of this program is to provide the opportunity for researchers outside IMSUT to conduct cooperative research activities with IMSUT scientists in the 3 research areas described above.
Successful applicants and project members may use IMSUT facilities by permission of the host scientist involved.

2. Eligibility of applicants
The applicant must be a researcher at a university or public research institute.

3. Duration of Joint Research
Support period: 1 year, lasting from 1 April 2012 until 31 March 2013.
Support period can be extended up to 3 years, however, application for extension is required for each fiscal year.
Regardless of the support period, the applicant is required to fill in the entire period of the Joint Research on the application form. Duration should be from 1 year up to 3 years.

4. Application Procedure
The applicant is required to submit Application Form "1" and "3" to IMSUT.
Before submitting the application, the applicant must contact closely with the prospective IMSUT host scientist. (
Application forms can be downloaded from the following website.
Form 1 (Application for Joint Research Project) PDF   MS WORD
Form 2 (Report: Progress Report is required from the applicant for extension) PDF   MS WORD
Form 3 (Letter of Consent and Acceptance Letter). Arbitrary format.
a. Letter of Consent by the head of the institution to which the applicant belongs.
b. Letter of Consent by any other project member, if he/she belongs to an institution other than the applicant's.
c. Acceptance Letter of the prospective host scientist in IMSUT.

5. Deadline
30 November, 2011
Applications submitted after the deadline will not be accepted regardless of the reason.

6. Submission of Applications
Research Cooperation Section
The Institute of Medical Science, The University of Tokyo
4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639
TelF03-5449-5751 FaxF03-5449-5402

7. Notification of selection results
Notification of the selection results will be made in writing by the middle of March 2012.

8. Research Funding
IMSUT will cover the expenses to conduct the approved Joint Research Project such as expendable supplies used in IMSUT, domestic travel expenses between IMSUT and the applicant's institution, etc, up to 1,000,000 yen per fiscal year.

9. Report Submission
Progress Report
-At the end of each fiscal year, a research-progress report should be submitted in the prescribed format.
Project-completion Report
-At the end of the research period or at the time a project ends if terminated midstream, a research-results report should be submitted in the prescribed format.