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Publications List
 
 
 
  1. Noguchi R, Yamaguchi K, Ikenoue T, Terakado Y, Ohta Y, Yamashita N, Kainuma O, Yokoi S, Maru Y, Nagase H, Furukawa Y. Genetic alterations in Japanese extrahepatic biliary tract cancer. Oncology Letters, 2017 in press.

  2. Zhu C, Yamaguchi K, Osugi T, Terakado Y, Noguchi R, Ikenoue T, Furukawa Y. Identification of FERM domain-containing protein 5 (FRMD5) as a novel target of ƒÀ-catenin/TCF7L2 complex. Cancer Sci, 2017 in press.

  3. Hirata M, Nagai A, Kamatani Y, Ninomiya T, Tamakoshi A, Yamagata Z, Kubo M, Muto K, Kiyohara Y, Mushiroda T, Murakami Y, Yuji K, Furukawa Y, Zembutsu H, Tanaka T, Ohnishi Y, Nakamura Y; BioBank Japan Cooperative Hospital Group., Matsuda K. Overview of BioBank Japan Follow-up Data in 32 Diseases. J Epidemiol. 27(3S):S22-S28, 2017.

  4. Hirata M, Kamatani Y, Nagai A, Kiyohara Y, Ninomiya T, Tamakoshi A, Yamagata Z, Kubo M, Muto K, Mushiroda T, Murakami Y, Yuji K, Furukawa Y, Zembutsu H, Tanaka T, Ohnishi Y, Nakamura Y. BioBank Japan Cooperative Hospital Group., Matsuda K. Cross-sectional analysis of BioBank Japan Clinical Data: A Large Cohort of 200,000 Patients with 47 Common Diseases. J Epidemiol. 27(3S):S9-S21, 2017.

  5. Nagai A, Hirata M, Kamatani Y, Muto K, Matsuda K, Kiyohara Y, Ninomiya T, Tamakoshi A, Yamagata Z, Mushiroda T, Murakami Y, Yuji K, Furukawa Y, Zembutsu H, Tanaka T, Ohnishi Y, Nakamura Y; BioBank Japan Cooperative Hospital Group., Kubo M. Overview of the BioBank Japan Project: Study Design and Profile. J Epidemiol. 27(3S):S2-S8, 2017.

  6. Fujii T, Tsunesumi S, Sagara H, Munakata M, Hisaki Y, Sekiya T, Furukawa Y, Sakamoto K, Watanabe S. Smyd5 plays pivotal roles in both primitive and definitive hematopoiesis during zebrafish embryogenesis. Scientific Reports, 6:29157, 2016.

  7. Yamaguchi K, Nagayama S, Shimizu E, Komura M, Yamaguchi R, Shibuya T, Arai M, Hatakeyama S, Ikenoue T, Ueno M, Miyano S, Imoto S, Furukawa Y. Reduced expression of APC-1B but not APC-1A by the deletion of promoter 1B is responsible for familial adenomatous polyposis. Scientific Reports, 6:26011, 2016.

  8. Ikenoue T, Terakado Y, Nakagawa H, Hikiba Y, Fujii T, Matsubara D, Noguchi R, Zhu C, Yamamoto K, Kudo Y, Asaoka Y, Yamaguchi K, Ijichi H, Tateishi K, Fukushima N, Maeda S, Koike K, Furukawa Y. A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion. Scientific Reports, 6:23899, 2016.

  9. Amagai Y, Fujiyuki T, Yoneda M, Shoji K, Furukawa Y, Sato H, Kai C. Oncolytic Activity of a Recombinant Measles Virus, Blind to Signaling Lymphocyte Activation Molecule, Against Colorectal Cancer Cells. Sci Rep.6: 24572, 2016.

  10. Ingle JN, Xie F, Ellis MJ, Goss PE, Shepherd LE, Chapman J-A W, Chen BE, Kubo M, Furukawa Y, Momozawa Y, Stearns V, Pritchard KI, Barman P, Carlson EE, Goetz MP, Weinshilboum RM, Kalari KR, Wang L. Aromatase inhibitor efficacy pharmacogenomics and MIR2052HG long noncoding RNA polymorphisms Cancer Res, 76:7012-23, 2016.

  11. Hertz DL, Owzar K, Lessans S, Wing C, Jiang C, Kelly WK, Patel J, Halabi S, Furukawa Y, Wheeler HE, Sibley AB, Lassiter C, Weisman L, Watson D, Krens SD, Mulkey F, Renn CL, Small EJ, Febbo PG, Shterev I, Kroetz DL, Friedman PN, Mahoney JF, Carducci MA, Kelley MJ, Nakamura Y, Kubo M, Dorsey SG, Dolan ME, Morris MJ, Ratain MJ, McLeod HL. Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy. Clin Cancer Res, 22(19): 4890-4900, 2016..

  12. Yamaguchi K, Komura M, Yamaguchi R, Imoto S, Shimizu E, Kasuya S, Shibuya T, Hatakeyama S, Takahashi N, Ikenoue T, Hata K, Tsurita G, Shinozaki M, Suzuki Y, Sugano S, Miyano S, Furukawa Y. Detection of APC mosaicism by next-generation sequencing in an FAP patient. J Hum Genet, 60(5):227-31, 2015.

  13. Noguchi R, Yano H, Gohda Y, Suda R, Igari T, Ohta Y, Yamashita N, Yamaguchi K, Terakado Y, Ikenoue T, Furukawa Y. Molecular profiles of high grade and low grade pseudomyxoma peritonei. Cancer Medicine, 4(12):1809-16, 2015.

  14. Ikenoue T, Yamaguchi K, Komura M, Imoto S, Yamaguchi R, Shimizu E, Kasuya S, Shibuya T, Hatakeyama S, Miyano S, Furukawa Y. Attenuated familial adenomatous polyposis with desmoids by an APC mutation. Hum Genome Variation, 2:15011, 2015.

  15. Iwaizumi M, Tao H, Yamaguchi K, Yamada H, Shinmura K, Kahyo T, Yamanaka Y, Kurachi K, Sugimoto K, Furukawa Y. and Sugimura H. A novel APC mosaicism in a patient with familial adenomatous polyposis. Hum Genome Variation. 2:15057, 2015.

  16. Tanakaya K, Furukawa Y, Nakamura Y, Hirata K, Tomita N, Tamura K, Sugano K, Ishioka C, Yoshida T, Ishida H, Watanabe T, Sugihara K; HNPCC registry and genetic testing project of the Japanese Society for Cancer of the Colon and Rectum, Yamaguchi T, Ishikawa H, Matsubara N, Arai M, Moriya Y. Relationship between smoking and multiple colorectal cancers in patients with Japanese Lynch syndrome: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum. Jpn J Clin Oncol. 45(3):307-10, 2015.

  17. Takahashi N, Yamaguchi K, Ikenoue T, Fujii T, Furukawa Y. Identification of two Wnt-responsive elements in the intron of RING Finger Protein 43 (RNF43) gene. PLoS ONE, 9: e86582, 2014.

  18. Deng Z, Matsuda K, Tanikawa C, Lin J, Furukawa Y, Hamamoto R, Nakamura Y. Late Cornified Envelope Group I, a Novel Target of p53, Regulates PRMT5 Activity. Neoplasia. 16(8):656-64, 2014.

  19. Liu M, Goss PE, Ingle JN, Kubo M, Furukawa Y, Batzler A, Jenkins GD, Carlson EE, Nakamura Y, Schaid DJ, Chapman JA, Shepherd LE, Ellis MJ, Khosla S, Wang L, Weinshilboum RM. Mol Endocrinol. Aromatase Inhibitor-Associated Bone Fractures: A Case-Cohort GWAS and Functional Genomics. 28(10):1740-51, 2014.

  20. Yamaguchi K, Rui Yamaguchi R, Takahashi N, Ikenoue T, Fujii T, Shinozaki M, Tsurita G, Hata K, Niida A, Imoto S, Miyano S, Nakamura Y, Furukawa Y. Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer. PLoS ONE, 9: e85750, 2014.

  21. Hiramoto T, Ebihara Y, Mizoguchi Y, Nakamura K, Yamaguchi K, Ueno K, Michizuki S, Yamamoto S, Nagasaki M, Furukawa Y, Tani K, Nakauchi H, Kobayashi M, Tsuji K. Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia patient-derived pluripotent stem cells. Proc. Natl. Acad. Sci. USA, 110(8):3023-3028, 2013.

  22. Yamamoto S, Ebihara Y, Mochizuki S, Kawakita T, Kato S, Ooi J, Takahashi S, Tojo A, Yusa N, Furukawa Y, Oyaizu N, Watanabe J, Sato K, Kimura F, Tsuji K. Quantitative PCR detection of CEP110-FGFR1 fusion gene in a patient with 8p11 syndrome. Leuk Lymphoma. 54(9): 2068-9, 2013.

  23. 5. Shigeyasu K, Tanakaya K, Nagasaka T, Aoki H, Fujiwara T, Sugano K, Ishikawa H, Yoshida T, Moriya Y, Furukawa Y, Goel A, Takeuchi H. Early detection of metachronous bile duct cancer in Lynch syndrome: report of a case. Surg Today. Jul 31, 2013.

  24. Takahashi M, Furukawa Y, Shimodaira H, Sakayori M, Moriya T, Moriya Y, Nakamura Y, Ishioka C. Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome. Fam Cancer 11i4j:559-64, 2012.

  25. Tanikawa C, Nakagawa H, Furukawa Y, Nakamura Y, Matsuda K. CLCA2 as a p53-inducible senescence mediator. Neoplasia. 14(2):141-9, 2012.

  26. Yamaguchi K, Sakai M, Kim JH, Shin-ichiro Tsunesumi S, Fujii T, Ikenoue T, Yamada Y, Akiyama Y, Muto Y, Yamaguchi R, Miyano S, Nakamura Y, Furukawa Y. MRG-binding protein contributes to development of colorectal cancer. Cancer Science, 102(8):1486-92, 2011.

  27. Fujii T, Tsunesumi S, Yamaguchi K, Watanabe S, & Furukawa Y; Smyd3 is required for the development of cardiac and skeletal muscle in zebrafish. PLoS One 6(8): e23491, 2011.

  28. Yamamoto K, Ishida T, Nakano K, Yamagishi M, Yamochi T, Tanaka Y, Furukawa Y, Nakamura Y, Watanabe T. SMYD3 interacts with HTLV-1 Tax and regulates sub-cellular localization of Tax. Cancer Science 102: 260-266, 2011.

  29. Kaneko M, Nozawa H, Kitayama J, Sunami E, Akahane M, Yamauchi N, Furukawa Y, Nagawa H, A case of hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease) with multiple polyps arising in the cecum and appendix. Acta Gastroenterol Belg 74(2):352-354, 2011.

  30. Yamaguchi K, Sakai M, Shimokawa T, Yamada Y, Nakamura Y, Furukawa Y, C20orf20 (MRG-binding protein) as a potential therapeutic target for colorectal cancer. Br. J. Cancer 102:325-31, 2010

  31. Inoue M., Senju S., Hirata S., Ikuta Y., Hayashida Y., Irie A., Harao M., Imai K., Tomita Y., Tsunoda T., Furukawa Y., Ito T., Nakamura Y., Baba H., Nishimura Y. Identification of SPARC as a candidate target antigen for immunotherapy of various cancers. International Journal of Cancer. 127: 1393-1403, 2010.

  32. Stefanou N, Papanikolaou V, Furukawa Y, Nakamura Y, Tsezou A. Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase. BMC Cancer. 10(1):442, 2010.

  33. Nozawa H, Yamada Y, Muto Y, Endo J, Asakage M, Oka T, Furukawa Y, Arai M. Double primary adenocarcinomas of the jejunum and descending colon with lung metastases presenting rare immunohistochemical phenotypes: a case report.Eur J Gastroenterol Hepatol. 22:228-33, 2010.

  34. Moriwaki K, Noda K, Furukawa Y, Ohshima K, Uchiyama A, Nakagawa T, Taniguchi N, Daigo Y, Nakamura Y, Hayashi N, Miyoshi E. Deficiency of GMD leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling. Gastroenterology. 137: 188-198, 2009.

  35. Tanikawa C, Furukawa Y, Yoshida N, Arakawa H, Nakamura Y, Matsuda K, XEDAR as a putative colorectal tumor suppressor that mediates p53-regulated anoikis pathway. Oncogene. 28:3081-92, 2009.

  36. Naruse H, Ikawa N, Yamaguchi K, Nakamura Y, Arai M, Ishioka C, Sugano K, Tamura K, Tomita N, Matsubara N, Yoshida T, Moriya Y, Furukawa Y. Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay. Fam Cancer 8: 509-517, 2009.

  37. Silva FP, Hamamoto R, Kunizaki M, Tsuge M, Nakamura Y, Furukawa Y. Enhanced methyltransferase activity of SMYD3 by the cleavage of its N-terminal region in human cancer cells. Oncogene 27: 2686-2692, 2008.

  38. Kidokoro T, Tanikawa C, Furukawa Y, Katagiri T, Nakamura Y, Matsuda K. CDC20, a potential cancer therapeutic target, is negatively regulated by p53. Oncogene 27: 1562-1571. 2008.

  39. Obama K, Satoh S, Hamamoto R, Sakai Y, Nakamura Y, Furukawa Y. Enhanced expression of RAD51AP1 is involved in the growth of intrahepatic choloangiocarcinoma cells. Clinical Cancer Research, 14(5): 1333-1339, 2008.

  40. Kunizaki M, Hamamoto R, Silva FP, Yamaguchi K, Nagayasu T, Shibuya M, Nakamura Y, Furukawa Y. The lysine 831 of VEGFR1 a novel target of methylation by SMYD3. Cancer Research,67(22): 10759-10765, 2007.

  41. Ura K, Obama K, Satoh S, Sakai Y, Nakamura Y, Furukawa Y. Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma. Clinical Cancer Research, 12: 6611-6616, 2006

  42. Jinawath N, Chamgramol Y, Furukawa Y, Obama K, Tsunoda T, Sripa B, Pairojkul C, Nakamura Y. Comparison of gene expression profiles between opisthorchis viverrini and non-opisthorchis viverrini associated human intrahepatic cholangiocarcinoma. Hepatology 2006, 44: 1025-1038, 2006

  43. Shimokawa T, Matsushima S, Tsunoda T, Tahara H, Nakamura Y, Furukawa Y. Identifikation of TOMM34, which shows elevated expression in the mojority of human colon cancers, as a novel drug target. Internationarl Journal of Oncology, 29: 381-386, 2006

  44. Kobayashi T, Masaki T, Sugiyama M, Atomi Y, Furukawa Y, Nakamura Y. A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells. International Journal of Oncology 29:341-347 , 2006.

  45. Suda T, Tsunoda T, Uchida N, Watanabe T, Hasegawa S, Satoh S, Ohgi S, Furukawa Y, Nakamura Y, Tahara H. Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray. Cancer Science 97(5): 411-419, 2006.

  46. Silva FP, Hamamoto R, Furukawa Y, Nakamura Y. TIPUH1 encodes a novel KRAB zinc-finger protein highly expressed in human hepatocellular carcinomas. Oncogene 25: 5063-5070, 2006.

  47. Hamamoto R, Silva FP, Tsuge M, Nishidate T, Katagiri T, Nakamura Y, Furukawa Y. Enhanced SMYD3 expression is essential for the growth of breast cancer cells. Cancer Science 97(2): 113-118, 2006.

  48. Obama K, Kato T, Hasegawa S, Satoh S, Nakamura Y, Furukawa Y. Overexpression of peptidyl-prolyl isomerase-like1 is associated with the growth of colon cancer cells. Clinical Cancer Research 12 (1): 70-76, 2006.

  49. Sakai M, Shimokawa T, Kobayashi T, Matsushima S, Yamada Y, Nakamura Y, Furukawa Y. Elevated expression of C10orf3 (Chromosome 10 open reading frame 3) is involved in the growth of human colon tumor. Oncogene 25: 480-486, 2006.

  50. Takahashi, M., Nakamura, Y., Obama, K. Furukawa Y. Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer. International Journal of Oncology 27: 1483-1487, 2005.

  51. Sakai M, Shimokawa T, Kobayashi T, Matsushima S, Yamada Y, Nakamura Y, Furukawa Y. Elevated expression of C10orf3 (Chromosome 10 open reading frame 3) is involved in the growth of human colon tumor. Oncogene 19: 1-7, 2005.

  52. Tsuge M, Hamamoto R, Silva FP, Ohnishi Y, Chayama K, Kamatani N, Furukawa Y, Nakamura Y. VNTR Polymorphism of E2F-1 binding element in the 5Õ flanking region of SMYD3 is a risk factor for human cancers. Nature Genetics 37(10): 1104-1107, 2005.

  53. Watanabe T, Suda T, Tsunoda T, Uchida N, Ura K, Kato T, Hasegawa S, Satoh S, Ohgi S, Tahara H, Furukawa Y, Nakamura Y. Identification of Immunoglobulin superfamily 11 (IGSF11) as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas. Cancer Science 96(8): 498-506, 2005.

  54. Obama K, Ura K, Satoh S, Nakamura Y, Furukawa Y. Up-regulation of PSF2, a member of multiprotein complex GINS, involved in cholangiocarcinogenesis. Oncology Report 14: 701-706, 2005.

  55. Silva FP, Hamamoto R, Nakamura Y, Furukawa Y. WDRPUH, a novel WD-repeat containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation. Neoplasia 7(4): 348-355, 2005.

  56. Obama K, Ura K, Li M, Katagiri T, Tsunoda T, Nomura A, Satoh S, Nakamura Y, Furukawa Y. Genome-wide analysis of gene expression in human intrahepatic cholangiocarcinomas. Hepatology 41(6): 1339-1348, 2005.

  57. Yagyu R, Furukawa Y, Lin Y-M, Shimokawa T, Yamamura T, Nakamura Y. A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer. International Journal of Oncology 25(5): 1343-1348, 2004.

  58. Takahashi M, Lin Y-M, Nakamura Y, Furukawa Y. Isolation and characterization of a novel gene CLUAP1 whose expression is frequently upregulated in colon cancer. Oncogene 23(57): 9289-9294, 2004.

  59. Jinawath N, Furukawa Y, Hasegawa S, Li M, Tsunoda T, Satoh S, Yamaguchi T, Imamura H, Inoue M, Shiozaki H, Nakamura Y. Comparison of gene-expression profiles between diffuse- and intestinal-type gastric cancers using a genome-wide cDNA microarray. Oncogene 23(40): 6830-6844, 2004.

  60. Yuki D, Lin Y-M, Fujii Y, Nakamura Y, Furukawa Y. Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers. Oncology Report 12(2): 275-280, 2004.

  61. Hamamoto R, Furukawa Y, Morita M, Iimura Y, Silva FP, Li M, Yagyu R, Nakamura Y. SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells. Nature Cell Biology 6(8): 731-740, 2004.

  62. Jinawath N, Furukawa Y, Nakamura Y. Identification of NOL8, a nucleolar protein containing an RNA recognition motif (RRM), which was overexpressed in diffuse-type gastric cancer. Cancer Science 95(5): 430-435, 2004.

  63. Li M, Lin Y-M, Hasegawa S, Shimokawa T, Murata K, Kameyama M, Ishikawa O, Katagiri T, Tsunoda T, Nakamura Y, Furukawa Y. Genes associated with liver metastasis of colon cancer, identified by genome-wide cDNA microarray. International Journal of Oncology 24: 305-312, 2004.

  64. Okabe H, Furukawa Y, Kato T, Hasegawa S, Yamaoka Y, Nakamura Y. Isolation of DDEFL1 (Development and Differentiation Enhancing Factor Like 1) as a drug target for hepatocellular carcinomas. International Journal of Oncology 24: 43-48, 2004.

  65. Shimokawa T, Furukawa Y, Sakai M, Li M, Miwa N, Lin Y-M, Nakamura Y. Involvement of FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the ƒÀ-catenin/Tcf complex. Cancer Research 63: 6116-6120, 2003.

  66. Okabe H, Satoh S, Furukawa Y, Kato T, Hasegawa S, Nakajima Y, Yamaoka Y, Nakamura Y. Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1. Cancer Research 63: 3043-3048, 2003.

  67. Hasegawa S, Furukawa Y, Li M, Satoh S, Kato T, Watanabe T, Katagiri T, Tsunoda T, Yamaoka Y, Nakamura Y. Genome-wide analysis of gene expression in intestinal-type gastric cancers using a complementary DNA microarray representing 23,040 genes. Cancer Research 62: 7012-7017, 2002.

  68. Takahashi M, Fujita M, Furukawa Y, Hamamoto R, Shimokawa T, Miwa N, Ogawa M, Nakamura Y. Isolation of a novel human gene, APCDD1, as a direct target of the ƒÀ-catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis. Cancer Research 62: 5651-5656, 2002.

  69. Ishiguro H, Shimokawa T, Tsunoda T, Tanaka T, Fujii Y, Nakamura Y, Furukawa Y. Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas. Oncogene 21: 6387-6394, 2002.

  70. Takahashi M, Tsunoda T, Seiki M, Nakamura Y, Furukawa Y. Identification of membrane-type matrix metalloproteinase-1 as a target of the ƒÀ-catenin/Tcf4 complex in human colorectal cancers. Oncogene 21: 5861-5867, 2002.

  71. Lin Y-M, Furukawa Y, Tsunoda T, Yue C-T, Yang K-C, Nakamura Y. Molecular diagnosis of colorectal tumors by expression profiles of 50 genes expressed differentially in adenomas and carcinomas. Oncogene 21: 4120-4128, 2002.

  72. Yagyu R, Hamamoto R, Furukawa Y, Okabe H, Yamamura T, Nakamura Y. Isolation and characterization of a novel human gene, VANGL1, as a therapeutic target for hepatocellular carcinoma. International Journal of Oncology 20: 1173-1178, 2002.

  73. Iizaka M, Furukawa Y, Tsunoda T, Akashi H, Ogawa M, Nakamura Y. Expression profile analysis of colon cancer cells in response to sulindac or aspirin.@ Biochemical and Biophysical Research Communications 292: 498-512, 2002.

  74. Miwa N, Furuse M, Tsukita S, Niikawa N, Nakamura Y, Furukawa Y. Involvement of claudin-1 in the _-catenin/Tcf signaling pathway and its frequent up-regulation in human colorectal cancers. Oncology Research 12: 469-476, 2001.

  75. Fujita M, Furukawa Y, Tsunoda T, Tanaka T, Ogawa M, Nakamura Y. Up-regulation of the ENC1 (ectodermal-neural cortex 1) gene, a down-stream target of the _-catenin/Tcf complex, in colorectal carcinomas. Cancer Research 61: 7722-7726, 2001.

  76. Yanagawa R, Furukawa Y, Tsunoda T, Kitahara O, Murata K, Ishikawa O, Nakamura Y. Genome-wide screening of genes showing altered expression in liver metastases of human colorectal cancers by cDNA microarray. Neoplasia 3: 395-401, 2001.

  77. Ishiguro H, Furukawa Y, Tsunoda T, Tanaka T, Fujii Y, Nakamura Y. Identification of AXUD1, a novel human gene induced by AXIN1 and involved in human carcinogenesis of the lung, liver, colon and kidney. Oncogene 20: 5062-5066, 2001.

  78. Kihara C, Tsunoda T, Tanaka T, Yamana H, Furukawa Y, Ono K, Kitahara O, Zembutsu H, Yanagawa R, Hirata K, Takagi T, Nakamura Y. Prediction of sensitivity of esophageal tumors to adjuvant chemotherapy by cDNA microarray analysis of gene-expression profiles. Cancer Research 61: 6474-6479, 2001.

  79. Lin Y-M, Ono K, Satoh S, Ishiguro H, Fujita M, Miwa N, Tanaka T, Tsunoda T, Yang K-C, Nakamura Y, Furukawa Y. Identification of AF17 as a downstream gene of the ƒÀ-catenin/Tcf pathway, and its involvement in colorectal carcinogenesis. Cancer Research 61: 6345-6349, 2001.

  80. Furukawa Y, Kawasoe T, Daigo Y, Nishiwaki T, Ishiguro H, Takahashi M, Kitayama J, Nakamura Y. Isolation of a novel human gene, ARHGAP9, encoding a rho-GTPase activating protein. Biochemical and Biophysical Research Communications 284(3): 643-649, 2001.

  81. Kato T, Satoh S, Okabe H, Kitahara O, Ono K, Kihara C, Tanaka T, Tsunoda T, Yamaoka Y, Nakamura Y, Furukawa Y. Isolation of a novel human gene, MARKL1, homologous to MARK3 and its involvement in hepatocellular carcinogenesis. Neoplasia 3: 4-9, 2001.

  82. Kitahara O, Furukawa Y, Tanaka T, Kihara C, Ono K, Yanagawa R, Nita EM, Ogasawara H, Okutsu J, Zenbutsu H, Shiraishi N, Takagi T, Nakamura Y, Tsunoda T. Alterations of gene expression during colorectal carcinogenesis revealed by cDNA microarrays after laser-capture microdissection of tumor tissues and normal epithelia. Cancer Research 61: 3544-3549, 2001.

  83. Okabe H, Satoh S, Kato T, Kitahara O, Yanagawa R, Yamaoka Y, Tsunoda T, Furukawa Y, Nakamura Y. Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray ; Identification of genes involved in viral carcinogenesis and tumor progression. Cancer Research 61(5): 2129-2137, 2001.

  84. Fujita M, Furukawa Y, Nagasawa Y, Ogawa M, Nakamura Y. Down-regulation of monocyte chemotactic protein-3 (MCP-3) expression by activated ƒÀ-catenin. Cancer Research 60(23): 6683-6687, 2000.

  85. Lin Y-M, kato T, Satoh S, Nakamura Y, Furukawa Y. Identification of novel polymorphisms in the AXIN1 and CDX-2 genes. Journal of Human Genetics 45: 254-256, 2000.

  86. Kawasoe T, Furukawa Y, Daigo Y, Nishiwaki T, Ishiguro H, Fujita M, Satoh S, Miwa N, Nagasawa Y, Miyoshi Y, Ogawa M, Nakamura Y. Isolation and characterization of a novel human gene, DRCTNNB1A, whose expression is down-regulated by ƒÀ-catenin. Cancer Research 60(13): 3354-3358, 2000.

  87. shiguro H, Furukawa Y, Daigo Y, Miyoshi Y, Nagasawa Y, Nishiwaki T, Kawasoe T, Fujita M, Satoh S, Miwa N, Fujii Y, Nakamura Y. Isolation and characterization of human NBL4, a gene involved in the ƒÀ-catenin/Tcf signaling pathway. Japanese Journal of Cancer Research 91: 597-603, 2000.

  88. Akashi H, Han H-J, Iizaka M, Nakajima Y, Furukawa Y, Sugano S, Imai K, Nakamura Y. Isolation and characterization of a novel gene encoding a putative seven-span transmembrane protein, TM7SF3. Cytogenetics and Cell Genetics 88: 305-309, 2000.

  89. Iizaka M, Han H-J, Akashi H, Furukawa Y, Nakajima Y, Sugano S, Ogawa M, Nakamura Y. Isolation and chromosomal assignment of a novel human gene, CORO1C, homologous to coronin-like actin-binding proteins. Cytogenetics and Cell Genetics 88: 221-224, 2000.

  90. Kihara C, Seki T, Furukawa Y, Yamana H, Kimura Y, van Schaardenburgh P, Hirata K, Nakamura Y. Mutations in zinc-binding domains of p53 as a prognostic marker of esophageal cancer patients. Japanese Journal of Cancer Research 91: 190-198, 2000.

  91. Satoh S, Daigo Y, Furukawa Y, Kato T, Miwa N, Nishiwaki T, Kawasoe T, Ishiguro H, Fujita M, Tokino T, Sasaki Y, Imaoka S, Murata M, Shimano T, Yamaoka Y, Nakamura Y. AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Nature Genetics 24(3): 245-250, 2000.

  92. Akashi H, Han HJ, Iizaka M, Nakajima Y, Furukawa Y, Sugano S, Imai K, Nakamura Y. Isolation and characterization of a human cDNA encoding a protein homologous to the 7.2-kDa protein (subunit X) of bovine ubiquinol-cytochrome C reductase. Journal of Human Genetics 45(1): 43-46, 2000.

  93. Daigo Y, Furukawa Y, Kawasoe T, Ishiguro H, Fujita M, Sugai S, Nakamori S, Liefers GJ, Tollenaar RA, van de Velde CJ, Nakamura Y. Absence of genetic alteration at codon 531 of the human c-src gene in 479 advanced colorectal cancers from Japanese and Caucasian patients. Cancer Research 59(17): 4222-4224, 1999.

  94. Nishiwaki T, Daigo Y, Kawasoe T, Nagasawa Y, Ishiguro H, Fujita M, Furukawa Y, Nakamura Y. Isolation and characterization of a human cDNA homologous to the Xenopus laevis XCAP-C gene belonging to the structural maintenance of chromosomes (SMC) family. Journal of Human Genetics 44(3): 197-202, 1999.
 
 
 
 

 

 

 

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