Advanced Clinical Research Center
Division of Clinical Immunology
Professor Chikao Morimoto

Our long term goal is to define the molecular and structural basis for the mechanisms of the immune abnormalities observed in various immune-mediated disorders such as autoimmune disease as well as to cure patients suffering from the above immune-mediated disorders. To accomplish this goal, we have focused on defining the structure and function of cell surface and intracellular molecules expressed in human T cells and other cells and on understanding how the immune regulatory system works in normal and disease conditions. Moreover, we will establish the translational research to cure such diseases. Our study will provide new insights into understanding the precise molecular mechanisms that underlie immune abnormalities found in various autoimmune diseases as well as other immune-mediated disorders and will lead to the development of new rational therapy for the manipulation of the abnormalities found in such diseases.