研究者紹介


 

氏名

各務 秀明(かがみ ひであき)

職名

寄付研究部門教員 客員助教授

所属名

幹細胞組織医工学寄付研究部門

研究分野

組織工学、再生医学、口腔外科学

研究課題

唾液線、口腔組織を中心とした組織工学的手法による再生医療、細胞治療に関する研究。細胞培養の効率化、安全性に関する研究など。

著書・学術論文題目(2004年以降)

 

  

1.Ozeki M, Narita Y, Kagami H, Ohmiya N, Itoh A, Hirooka Y, Niwa Y, Ueda M, Goto H.
Evaluation of decellularized esophagus as a scaffold for cultured esophageal epithelial cells
J Biomed Mater Res A, 2006 in press.

2.Murase Y, Narita Y, Kagami H, Miyamoto K, Ueda Y, Ueda M, Murohara T.

Evaluation of Compliance and Stiffness of Decellularized Tissue as Scaffolds for Tissue-Engineered Small Caliber Vascular Grafts Using Intravascular Ultrasound.

ASAIO Journal 2006 in press.


3.Narita Y, Fukuhira Y, Kagami H, Kitazono E, Kaneko H, Sumi Y, Usui A, Ueda M, Ueda Y.

Development of a Novel Temporary Epicardial Pacing Wire with Biodegradable Film.

Ann Thorac Cardiovasc Surg 2006 in press.

 

4.Honda MJ, Shinohara Y, Sumita Y, Tonomura A, Kagami H, Ueda M. 

Shear stress facilitates tissue ?engineered odontogenesis . Bone 2006 in press.


5.Ohno K, Hattori T,  Kagami H*, and Ueda M

Effects of Preceding Sialadenitis on Development of Autoimmunity against Salivary Gland.
Oral Diseases in press.
 

6.Mase J, Mizuno H, Okada K, Sakai K, Mizuno D, Usami K, Kagami H, Ueda M.

Cryopreservation of cultured periosteum: Effect of different cryoprotectants and pre-incubation protocols on cell viability and osteogenic potential.

Cryobiology,52:182-192,2006. 


7.
Matsunuma H, Kagami H, Narita Y, Hata K, Ono Y, Oshima S, Ueda M. 

Constructing  a Tissue- Engineered Ureter Using a Decellularized Matrix with Cultuerd Uroepithelial Cells and Bone Marrow-Derived Mononuclear Cells.

Tissue Eng 12:509-518, 2006.

 

8.Sumita Y, Honda MJ, Ohara T, Tsuchiya S, Sagara H, Kagami H, Ueda M. 

Performance of collagen sponge as a 3-D scaffold for tooth-tissue engineering

Biomaterials27,3238-3248, 2006.

 
9.Honda MJ, Ohara T, Sumita Y, Ogaeri T, Kagami H, Ueda M.  
Preliminary study of tissue-engineered odontogenesis in the canine jaw
J Oral Maxillofac Surg ,2006,64(2):283-9.

 

2005

1.Tatebe M, Nakamura R, Kagami  H, Okada K, Ueda M.

Differentiation of transplanted mesenchymal stem cells in a large osteochondral defect in rabbit. Cyototherapy
2005 Dec;7(6):520-530
 
2.Ito A, Ino K. Hayashida M, Kobayashi T, Matsunuma H, Kagami H, Ueda M, Konda H.
Nove methodology for fabrication of tissue-engineered tubular constructs using magnetite nanoparticles and magnetic force.
Tissue Eng. 2005, 11(9-10):1553-1561
 
3.Kobayashi C, Kagami H, Kito K, Ishikawa K, Ebisawa K, Ueda M, Terasaki H.
Selective and Effecient Culturing of Retinal Pigment Epithelial Cells. Using a Feeder Layer
Cytotherapy 2005;7(5):427-437.
 
4.Michael A Hale, Kagami H, Ling Shi, Andrew M Holland, Hans-Peter Elsasser, PhD;
Robert E Hammer, Raymond J. MacDonald*. The homeodomain protein PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreas.
Dev Biol. 2005 286:225-237.
 
5.Honda MJ*, Sumita Y, Kgami H, Ueda M.
Histological and immunohistochemical studies of tissue engineered odontogenesis.
Arch Histol Cytol. 2005, 68(2):89-101
 
6.Ito A, Hibino E, Kobayashi C, Terasaki H, Kagami H, Ueda M, Kobayashi T, Honda H*
Construction and delibery of tissue-engineered human retinal pigment epithelial cell sheets, using magnetite nanoparticles and magnetic force.
Tissue Eng 11:489-496,2005.
 
7Kito K, Kagami H, Kobayashi C, Ueda M, Terasaki H*
Effects of cryopreservation on histology and viability of cultured corneal epithelial cell sheets in rabbit.
Cornea 24:735-741, 2005.
 
8.Seko K, Kagami H*, Senga K, Ozeki K, Mizutani H, Ueda M.
Effects of Ovariectomy and estrogen replacement on rat oral mucosa.
Maturitas 50(1): 44-51, 2005.
 

2004

1. Narita Y*, Hata K, Kagami H, Usui A, Ueda M, Ueda Y.

Novel Pulse Duplicating Bioreactor System for Tissue-Engineered Vascular Construct.

Tissue Engineering 10(7-8): 1224-1233, 2004.

 

2.Sugito T, Kagami H*, Hata K, Nishiguchi H, Ueda M

Transplantation of cultured salivary gland cells into an atrophic salivary gland.

Cell Transplantation 13: 691-699, 2004.

 
3. Miyata Y, Okada K, Fujimoto A, Hata K, Kagami H, Tomita Y*, Ueda M:

The effect of the long-term cultivation on telomere length and morphology of cultured epidermis,

Journal of Dermatological Science 34(3): 221-30, 2004.
 

4.Ito A, Hayashida M, Honda H, Hata K, Kagami H, Ueda M and Kobayashi T*.

Construction and harvest of multilayered keratinocyte sheets using magnetite nanoparticles and magnetic force.

Tissue Engineering 10(5-6): 873-80, 2004.

 

5.Ito A, Takizawa Y, Honda H, Hata K, Kagami H, Ueda M and Kobayashi T*.

Tissue engineering using magnetite nanoparticles and magnetic force: heterotypic layers of cocultured hepatocytes and endothelial cells.

Tissue Engineering 10(5-6): 833-840, 2004.

 

6.Ito A, Hibino E, Honda H, Hata K, Kagami H, Ueda M and Kobayashi T*.

A new methodology of mesenchymal stem cell expansion using magnetic nanoparticles.

Biochem Eng J. 20: 119-125, 2004

 

7.Maeda H., Kasuga T*, Nogami M, Kagami H, Hata K, Ueda M.

Preparation of bonelike apatite composite sponge.

Key Engineering Materials 254: 497-500, 2004.

 

8.Oda Y, Kagami H*, Ueda M

Accelerating effects of basic fibroblast growth factor on wound healing of rat palatal mucosa.

J Oral Maxillofac Surg 62(1): 73-80, 2004.

 

 

和文論文

1.大屋盛道,山田陽一,和田圭祐,渡邊和代,小澤亮太郎,岡崎恭宏,日比英晴,各務秀明,畠賢一郎,上田実 
間葉系幹細胞とPRP複合体を用いた上顎洞底挙上述における骨造成法の実験的研究
口外誌 50(10): 559-566, 2004

2.松沼寛,大島伸一,成田裕司,各務秀明,上田実
泌尿器科領域の再生医療:脱細胞化尿管と培養移行上皮細胞による尿管再生
西日本泌尿器科 66(3): 129-137, 2004



著書・総説等

1.山田陽一、各務秀明、上田 実
幹細胞を応用した歯周組織再生 「再生歯科のテクニックとサイエンス−歯周・審美・インプラント−」 第1編 歯周組織・再生 吉江弘正/宮本泰和編 
クインテッセンス出版株式会社、2005


2.各務秀明 
唾液による健康づくり−明日からの臨床に取り組む− Part 3 唾液のはたらき 12.唾液腺の再生医療は可能か? 
日本歯科評論 増刊2005 株式会社ヒョーロンパブリシャーズ 201-2082005


3.各務秀明,杉戸孝行,上田実 
増殖因子および培養細胞を用いた唾液腺の再生
口科誌 54(2): 211-215, 2005


4.本田雅規,小原孝之,住田吉慶,各務秀明,魚返拓利,上田実 
歯の再生−イヌ下顎骨への歯胚細胞移植 
「再生医療」 4(1)85-89, 2005


5.各務秀明,渡辺真紀,外村明子,安藤由典,本田雅規,上田実  
歯および歯胚由来細胞を用いた再生医療とその可能性
再生医療」 4(1):79-83, 2005


6.各務秀明,上田実  
再生医療の臨床応用と産業化
「小児外科」 36(11): 1383-1387, 2004


7.各務秀明,水野裕和,山田陽一,上田実  
細胞移植による歯周病の治療 
「治療学」 38(10):103-105, 2004


8.各務秀明,上田実  
ようこそ再生医療の世界へ−再生医療の将来と歯科- 
「歯科衛生士」 28(6):16-19, 2004


9.各務秀明,上田実  
ようこそ再生医療の世界へ−オリエンテーション− 
「歯科衛生士」 28(1):116-118, 2004


10.各務秀明,上田実  
再生医療の現状と展望 
「月刊新医療」 31(1):18-21, 2004